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Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples.

Lange OF, Rossi P, Sgourakis NG, Song Y, Lee HW, Aramini JM, Ertekin A, Xiao R, Acton TB, Montelione GT, Baker D,
Proceedings of the National Academy of Sciences of the United States of America (2012) 109:10873-8 PublishedPSI:Biology  
Northeast Structural Genomics Consortium

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We have developed an approach for determining NMR structures of proteins over 20 kDa that utilizes sparse distance restraints obtained using transverse relaxation optimized spectroscopy experiments on perdeuterated samples to guide RASREC Rosetta NMR structure calculations. ...
22733734  
10.1073/pnas.1203013109  
74 (Last update: 05/27/2017 11:31:47am)  
Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples
 
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