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Accurate protein structure modeling using sparse NMR data and homologous structure information.

Thompson JM, Sgourakis NG, Liu G, Rossi P, Tang Y, Mills JL, Szyperski T, Montelione GT, Baker D,
Proceedings of the National Academy of Sciences of the United States of America (2012) 109:9875-80 PublishedPSI:Biology  
Northeast Structural Genomics Consortium

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While information from homologous structures plays a central role in X-ray structure determination by molecular replacement, such information is rarely used in NMR structure determination because it can be incorrect, both locally and globally, when evolutionary relationships are inferred incorrectly or there has been considerable evolutionary structural divergence. ...
22665781  
PMC3382498  
10.1073/pnas.1202485109  
20 (Last update: 05/22/2017 6:34:50pm)  
CS-HM-Rosetta: Accurate protein structure modeling using sparse NMR data and homologous structure information
 
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