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Novel C-terminal Motif within Sec7 Domain of Guanine Nucleotide Exchange Factors Regulates ADP-ribosylation Factor (ARF) Binding and Activation.

Lowery J, Szul T, Seetharaman J, Jian X, Su M, Forouhar F, Xiao R, Acton TB, Montelione GT, Lin H, Wright JW, Lee E, Holloway ZG, Randazzo PA, Tong L, Sztul E,
Journal of Biological Chemistry (2011) 286:36898-906 PublishedPSI:Biology  
Northeast Structural Genomics Consortium

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ADP-ribosylation factors (ARFs) and their activating guanine nucleotide exchange factors (GEFs) play key roles in membrane traffic and signaling. ...
chemistry genetics metabolism 
Guanosine Triphosphate Protein Structure, Tertiary Amino Acid Substitution Humans GTPase-Activating Proteins HeLa Cells Amino Acid Motifs Catalysis Mutation, Missense ADP-Ribosylation Factors Guanine Nucleotide Exchange Factors Guanosine Diphosphate 
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