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Structural basis for the sequence-specific recognition of human ISG15 by the NS1 protein of influenza B virus.

Guan R, Ma LC, Leonard PG, Amer BR, Sridharan H, Zhao C, Krug RM, Montelione GT,
Proceedings of the National Academy of Sciences of the United States of America (2011) 108:13468-73 PublishedPSI:Biology  
Northeast Structural Genomics Consortium

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Interferon-induced ISG15 conjugation plays an important antiviral role against several viruses, including influenza viruses. ...
chemistry pharmacology metabolism 
Crystallography, X-Ray Protein Interaction Domains and Motifs Humans Cytokines Binding Sites Interferons Viral Nonstructural Proteins Protein Binding Ubiquitins Influenza B virus 
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