PSI Publications

View publication

PredUs: a web server for predicting protein interfaces using structural neighbors.
Authors:	Zhang QC, Deng L, Fisher M, Guan J, Honig B, Petrey D,
Journal:	Nucleic Acids Research (2011) 39:W283-7
Centers:	Northeast Structural Genomics Consortium
Abstract: (click to unfold)	We describe PredUs, an interactive web server for the prediction of protein-protein interfaces. ... Potential interfacial residues for a query protein are identified by 'mapping' contacts from known interfaces of the query protein's structural neighbors to surface residues of the query. We calculate a score for each residue to be interfacial with a support vector machine. Results can be visualized in a molecular viewer and a number of interactive features allow users to tailor a prediction to a particular hypothesis. The PredUs server is available at: http://wiki.c2b2.columbia.edu/honiglab_public/index.php/Software:PredUs.
Subheadings:	chemistry methods
Mesh Terms:	Binding Sites Algorithms Models, Molecular Protein Conformation Software Multiprotein Complexes Internet Protein Interaction Mapping Artificial Intelligence
Pubmed Id:	21609948
DOI:	10.1093/nar/gkr311
Times Cited:	44 (Last update: 10/13/2018 1:35:33pm)
Type:	method