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PredUs: a web server for predicting protein interfaces using structural neighbors.
Authors:	Zhang QC, Deng L, Fisher M, Guan J, Honig B, Petrey D,
Journal:	Nucleic Acids Research (2011) 39:W283-7
Centers:	Northeast Structural Genomics Consortium
Abstract: (click to unfold)	We describe PredUs, an interactive web server for the prediction of protein-protein interfaces. ... Potential interfacial residues for a query protein are identified by 'mapping' contacts from known interfaces of the query protein's structural neighbors to surface residues of the query. We calculate a score for each residue to be interfacial with a support vector machine. Results can be visualized in a molecular viewer and a number of interactive features allow users to tailor a prediction to a particular hypothesis. The PredUs server is available at: http://wiki.c2b2.columbia.edu/honiglab_public/index.php/Software:PredUs.
Subheadings:	chemistry methods
Mesh Terms:	Internet Models, Molecular Protein Conformation Protein Interaction Mapping Binding Sites Multiprotein Complexes Software Algorithms Artificial Intelligence
Pubmed Id:	21609948
DOI:	10.1093/nar/gkr311
Times Cited:	32 (Last update: 09/16/2017 11:26:43am)
Type:	method