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Novel anti-Prelog stereospecific carbonyl reductases from Candida parapsilosis for asymmetric reduction of prochiral ketones.

Nie Y, Xiao R, Xu Y, Montelione GT,
Organic & Biomolecular Chemistry (2011) 9:4070-8 PublishedPSI:Biology  
Northeast Structural Genomics Consortium

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The application of biocatalysis to the synthesis of chiral molecules is one of the greenest technologies for the replacement of chemical routes due to its environmentally benign reaction conditions and unparalleled chemo-, regio- and stereoselectivities. ...
chemistry genetics metabolism enzymology 
Ketones Models, Molecular Alcohol Oxidoreductases Molecular Structure Molecular Sequence Data Oxidation-Reduction Sequence Alignment Candida Stereoisomerism Biocatalysis Ethylene Glycols Substrate Specificity Amino Acid Sequence 
21505708  
10.1039/c0ob00938e  
47 (Last update: 04/01/2017 12:20:48pm)  
structure