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Novel anti-Prelog stereospecific carbonyl reductases from Candida parapsilosis for asymmetric reduction of prochiral ketones.

Nie Y, Xiao R, Xu Y, Montelione GT,
Organic & Biomolecular Chemistry (2011) 9:4070-8 PublishedPSI:Biology  
Northeast Structural Genomics Consortium

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The application of biocatalysis to the synthesis of chiral molecules is one of the greenest technologies for the replacement of chemical routes due to its environmentally benign reaction conditions and unparalleled chemo-, regio- and stereoselectivities. ...
metabolism chemistry genetics enzymology 
Amino Acid Sequence Models, Molecular Molecular Sequence Data Oxidation-Reduction Sequence Alignment Substrate Specificity Molecular Structure Stereoisomerism Alcohol Oxidoreductases Biocatalysis Candida Ethylene Glycols Ketones 
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