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Mass spectrometry guided in situ proteolysis to obtain crystals for X-ray structure determination.

Gheyi T, Rodgers L, Romero R, Sauder JM, Burley SK,
Journal of the American Society for Mass Spectrometry (2010) 21:1795-801 PublishedPSI:Phase 2  
New York Structural Genomics Research Consortium

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A strategy for increasing the efficiency of protein crystallization/structure determination with mass spectrometry has been developed. ...
metabolism chemistry methods 
Crystallography, X-Ray Proteins Escherichia coli Proteins Crystallization Mass Spectrometry Protein Conformation Peptide Hydrolases Peptide Fragments 
20685133  
10.1016/j.jasms.2010.06.015  
11 (Last update: 08/11/2018 5:59:28pm)  
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