|Journal of Structural and Functional Genomics (2009) 10:227-32|
|Northeast Structural Genomics Consortium|
(click to unfold)
Clean absorption mode NMR data acquisition is presented based on mirrored time domain sampling and widely used time-proportional phase incrementation (TPPI) for quadrature detection. ...
The resulting NMR spectra are devoid of dispersive frequency domain peak components. Those peak components exacerbate peak identification and shift peak maxima, and thus impede automated spectral analysis. The new approach is also of unique value for obtaining clean absorption mode reduced-dimensionality projection NMR spectra, which can rapidly provide high-dimensional spectral information for high-throughput NMR structure determination.
|chemistry methods metabolism |
|Protein Conformation Proteins Nuclear Magnetic Resonance, Biomolecular |
|4 (Last update: 05/27/2017 12:04:06pm)|
Clean absorption mode NMR data acquisition based on time-proportional phase incrementation