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Bacterial toxin YafQ is an endoribonuclease that associates with the ribosome and blocks translation elongation through sequence-specific and frame-dependent mRNA cleavage.

Prysak MH, Mozdzierz CJ, Cook AM, Zhu L, Zhang Y, Inouye M, Woychik NA,
Molecular Microbiology (2009) 71:1071-87 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Toxin-antitoxin (TA) systems on the chromosomes of free-living bacteria appear to facilitate cell survival during intervals of stress by inducing a state of reversible growth arrest. ...
metabolism genetics 
Antitoxins Bacterial Toxins Escherichia coli Ribosomes RNA, Messenger Endoribonucleases Substrate Specificity RNA, Bacterial Peptide Chain Elongation, Translational RNA Stability Escherichia coli Proteins 
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