View publication

Bacterial toxin YafQ is an endoribonuclease that associates with the ribosome and blocks translation elongation through sequence-specific and frame-dependent mRNA cleavage.

Prysak MH, Mozdzierz CJ, Cook AM, Zhu L, Zhang Y, Inouye M, Woychik NA,
Molecular Microbiology (2009) 71:1071-87 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

(click to unfold)
Toxin-antitoxin (TA) systems on the chromosomes of free-living bacteria appear to facilitate cell survival during intervals of stress by inducing a state of reversible growth arrest. ...
metabolism genetics 
Escherichia coli Escherichia coli Proteins Substrate Specificity RNA, Bacterial RNA, Messenger Ribosomes Peptide Chain Elongation, Translational Endoribonucleases Bacterial Toxins RNA Stability Antitoxins 
19210620  
10.1111/j.1365-2958.2008.06572.x  
87 (Last update: 11/10/2018 5:14:22pm)  
method