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Structural genomics is the largest contributor of novel structural leverage.

Nair R, Liu J, Soong TT, Acton TB, Everett JK, Kouranov A, Fiser A, Godzik A, Jaroszewski L, Orengo C, Montelione GT, Rost B,
Journal of Structural and Functional Genomics (2009) 10:181-91 PublishedPSI:Phase 2  
New York Consortium on Membrane Protein StructureJoint Center for Structural GenomicsMidwest Center for Structural GenomicsNortheast Structural Genomics ConsortiumNew York Structural Genomics Research Consortium

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The Protein Structural Initiative (PSI) at the US National Institutes of Health (NIH) is funding four large-scale centers for structural genomics (SG). ...
chemistry methods 
Computational Biology Databases, Protein Protein Conformation Proteomics Genomics Proteins Nuclear Magnetic Resonance, Biomolecular 
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