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Molecular basis of Pirh2-mediated p53 ubiquitylation.

Sheng Y, Laister RC, Lemak A, Wu B, Tai E, Duan S, Lukin J, Sunnerhagen M, Srisailam S, Karra M, Benchimol S, Arrowsmith CH,
Nature Structural & Molecular Biology (2008) 15:1334-42 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Pirh2 (p53-induced RING-H2 domain protein; also known as Rchy1) is an E3 ubiquitin ligase involved in a negative-feedback loop with p53. ...
chemistry metabolism 
Models, Molecular Protein Interaction Domains and Motifs Ubiquitination Protein Structure, Tertiary Magnetic Resonance Spectroscopy Molecular Sequence Data Protein Conformation Sequence Alignment Protein Interaction Mapping Tumor Suppressor Protein p53 Amino Acid Sequence Protein Binding Ubiquitin-Protein Ligases 
19043414  
10.1038/nsmb.1521  
49 (Last update: 04/01/2017 12:01:11pm)  
structure