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Automated identification of complementarity determining regions (CDRs) reveals peculiar characteristics of CDRs and B cell epitopes.

Ofran Y, Schlessinger A, Rost B,
Journal of Immunology (2008) 181:6230-5 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Exact identification of complementarity determining regions (CDRs) is crucial for understanding and manipulating antigenic interactions. ...
immunology metabolism instrumentation chemistry methods 
Amino Acids Protein Interaction Domains and Motifs Complementarity Determining Regions Antigen-Antibody Complex Binding Sites, Antibody Epitopes, B-Lymphocyte Databases, Protein Immunoglobulin Light Chains Structure-Activity Relationship Sequence Alignment Epitope Mapping Protein Folding Protein Structure, Secondary Immunoglobulin Heavy Chains 
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