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Automated identification of complementarity determining regions (CDRs) reveals peculiar characteristics of CDRs and B cell epitopes.

Ofran Y, Schlessinger A, Rost B,
Journal of Immunology (2008) 181:6230-5 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Exact identification of complementarity determining regions (CDRs) is crucial for understanding and manipulating antigenic interactions. ...
metabolism chemistry methods immunology instrumentation 
Databases, Protein Protein Structure, Secondary Sequence Alignment Protein Folding Structure-Activity Relationship Amino Acids Binding Sites, Antibody Epitope Mapping Protein Interaction Domains and Motifs Antigen-Antibody Complex Complementarity Determining Regions Epitopes, B-Lymphocyte Immunoglobulin Heavy Chains Immunoglobulin Light Chains 
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