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Bacterial addiction module toxin Doc inhibits translation elongation through its association with the 30S ribosomal subunit.

Liu M, Zhang Y, Inouye M, Woychik NA,
Proceedings of the National Academy of Sciences of the United States of America (2008) 105:5885-90 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Bacterial toxin-antitoxin (TA) systems (or "addiction modules") typically facilitate cell survival during intervals of stress by inducing a state of reversible growth arrest. ...
metabolism chemistry drug effects pharmacology 
Binding Sites Protein Binding Ribosomes Viral Proteins Protein Biosynthesis Bacteriophage P1 RNA Stability 
18398006  
10.1073/pnas.0711949105  
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