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Bacterial addiction module toxin Doc inhibits translation elongation through its association with the 30S ribosomal subunit.

Liu M, Zhang Y, Inouye M, Woychik NA,
Proceedings of the National Academy of Sciences of the United States of America (2008) 105:5885-90 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Bacterial toxin-antitoxin (TA) systems (or "addiction modules") typically facilitate cell survival during intervals of stress by inducing a state of reversible growth arrest. ...
chemistry pharmacology drug effects metabolism 
Bacteriophage P1 Ribosomes Binding Sites Protein Binding RNA Stability Viral Proteins Protein Biosynthesis 
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