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Molecular insights into the biosynthesis of the F420 coenzyme.

Forouhar F, Abashidze M, Xu H, Grochowski LL, Seetharaman J, Hussain M, Kuzin A, Chen Y, Zhou W, Xiao R, Acton TB, Montelione GT, Galinier A, White RH, Tong L,
Journal of Biological Chemistry (2008) 283:11832-40 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Coenzyme F(420), a hydride carrier, is found in Archaea and some bacteria and has crucial roles in methanogenesis, antibiotic biosynthesis, DNA repair, and activation of antitubercular compounds. ...
metabolism chemistry enzymology physiology 
Binding Sites Protein Structure, Tertiary Amino Acid Sequence Molecular Sequence Data Protein Binding Models, Chemical Catalysis Molecular Conformation Sequence Homology, Amino Acid Dimerization DNA Repair Gene Expression Regulation Methanosarcina Microscopy, Fluorescence NADH, NADPH Oxidoreductases 
18252724  
10.1074/jbc.M710352200  
24 (Last update: 11/17/2018 2:25:04pm)  
3C3D
3C3E
3CGW  
structure