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Molecular insights into the biosynthesis of the F420 coenzyme.

Forouhar F, Abashidze M, Xu H, Grochowski LL, Seetharaman J, Hussain M, Kuzin A, Chen Y, Zhou W, Xiao R, Acton TB, Montelione GT, Galinier A, White RH, Tong L,
Journal of Biological Chemistry (2008) 283:11832-40 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Coenzyme F(420), a hydride carrier, is found in Archaea and some bacteria and has crucial roles in methanogenesis, antibiotic biosynthesis, DNA repair, and activation of antitubercular compounds. ...
physiology enzymology metabolism chemistry 
Methanosarcina DNA Repair Microscopy, Fluorescence Protein Structure, Tertiary Dimerization Molecular Sequence Data Models, Chemical Binding Sites NADH, NADPH Oxidoreductases Amino Acid Sequence Protein Binding Sequence Homology, Amino Acid Catalysis Gene Expression Regulation Molecular Conformation 
18252724  
10.1074/jbc.M710352200  
21 (Last update: 03/18/2017 12:19:50pm)  
3C3D
3C3E
3CGW  
structure