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Natively unstructured loops differ from other loops.

Schlessinger A, Liu J, Rost B,
PLoS Computational Biology (2007) 3:e140 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Natively unstructured or disordered protein regions may increase the functional complexity of an organism; they are particularly abundant in eukaryotes and often evade structure determination. ...
analysis methods genetics metabolism chemistry 
Computer Simulation Proteome Caenorhabditis elegans Databases, Protein Structure-Activity Relationship Neural Networks (Computer) Predictive Value of Tests Models, Chemical Animals Protein Folding Protein Interaction Mapping Binding Sites Protein Structure, Secondary Amino Acid Sequence Artificial Intelligence Computational Biology Models, Molecular 
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