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Natively unstructured loops differ from other loops.

Schlessinger A, Liu J, Rost B,
PLoS Computational Biology (2007) 3:e140 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Natively unstructured or disordered protein regions may increase the functional complexity of an organism; they are particularly abundant in eukaryotes and often evade structure determination. ...
analysis metabolism chemistry methods genetics 
Computer Simulation Caenorhabditis elegans Databases, Protein Neural Networks (Computer) Predictive Value of Tests Models, Chemical Protein Folding Protein Interaction Mapping Binding Sites Protein Structure, Secondary Amino Acid Sequence Artificial Intelligence Computational Biology Models, Molecular Proteome Structure-Activity Relationship Animals 
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