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Structure-based activity prediction for an enzyme of unknown function.

Hermann JC, Marti-Arbona R, Fedorov AA, Fedorov E, Almo SC, Shoichet BK, Raushel FM,
Nature (2007) 448(7155):775-9 PublishedPSI:Phase 2  
New York Structural Genomics Research Consortium

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With many genomes sequenced, a pressing challenge in biology is predicting the function of the proteins that the genes encode. ...
analogs & derivatives metabolism enzymology chemistry 
Crystallography, X-Ray Homocysteine Inosine S-Adenosylhomocysteine Enzymes Nucleoside Deaminases Structure-Activity Relationship Protein Conformation Thionucleosides Adenine Thermotoga maritima Substrate Specificity Deamination Catalysis Deoxyadenosines Models, Molecular 
169 (Last update: 03/25/2017 12:03:24pm)  
Nature. 2007 Aug 16;448(7155):775-9. Epub 2007 Jul 1.