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Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery.

Khan JA, Forouhar F, Tao X, Tong L,
Expert opinion on therapeutic targets (2007) 11:695-705 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Nicotinamide adenine dinucleotide (NAD(+)) has crucial roles in many cellular processes, both as a coenzyme for redox reactions and as a substrate to donate ADP-ribose units. ...
metabolism physiology therapeutic use drug therapy drug effects antagonists & inhibitors pharmacology 
Humans Animals Signal Transduction Adenosine Diphosphate Ribose NAD Drug Design DNA Damage Mice Enzyme Inhibitors Tryptophan Neurodegenerative Diseases Acrylamides Aging Antineoplastic Agents Autoimmune Diseases Clinical Trials, Phase II as Topic Cyclic ADP-Ribose Kynurenine Neoplasms Neuroprotective Agents Piperidines Poly Adenosine Diphosphate Ribose Sirtuins 
17465726  
10.1517/14728222.11.5.695  
105 (Last update: 11/10/2018 3:09:21pm)  
2QL6
2QG6  
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