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Consensus sequences improve PSI-BLAST through mimicking profile-profile alignments.

Przybylski D, Rost B,
Nucleic Acids Research (2007) 35(7):2238-46 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Sequence alignments may be the most fundamental computational resource for molecular biology. ...
methods 
Amino Acid Substitution Sequence Alignment Base Sequence Amino Acid Sequence Consensus Sequence Software Sequence Analysis, Protein 
17369271  
10.1093/nar/gkm107  
8 (Last update: 04/01/2017 12:13:03pm)  
method  
Nucleic Acids Res. 2007;35(7):2238-46. Epub 2007 Mar 16.