View publication

The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53.

Kaustov L, Lukin J, Lemak A, Duan S, Ho M, Doherty R, Penn LZ, Arrowsmith CH,
Journal of Biological Chemistry (2007) 282(15):11300-7 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

(click to unfold)
Cul7 is a member of the Cullin Ring Ligase (CRL) family and is required for normal mouse development and cellular proliferation. ...
metabolism genetics 
Humans Protein Structure, Tertiary Amino Acid Motifs Conserved Sequence Models, Molecular Molecular Sequence Data Protein Binding Protein Structure, Quaternary Nuclear Magnetic Resonance, Biomolecular Carrier Proteins Cullin Proteins Tumor Suppressor Protein p53 
36 (Last update: 03/16/2019 7:37:27pm)  
J Biol Chem. 2007 Apr 13;282(15):11300-7. Epub 2007 Feb 12.