View publication

The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53.

Kaustov L, Lukin J, Lemak A, Duan S, Ho M, Doherty R, Penn LZ, Arrowsmith CH,
Journal of Biological Chemistry (2007) 282(15):11300-7 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

(click to unfold)
Cul7 is a member of the Cullin Ring Ligase (CRL) family and is required for normal mouse development and cellular proliferation. ...
genetics metabolism 
Models, Molecular Protein Structure, Quaternary Protein Structure, Tertiary Conserved Sequence Humans Molecular Sequence Data Tumor Suppressor Protein p53 Cullin Proteins Carrier Proteins Nuclear Magnetic Resonance, Biomolecular Protein Binding Amino Acid Motifs 
34 (Last update: 07/22/2017 11:37:52am)  
J Biol Chem. 2007 Apr 13;282(15):11300-7. Epub 2007 Feb 12.