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NMR and X-ray crystallography, complementary tools in structural proteomics of small proteins.

Yee AA, Savchenko A, Ignachenko A, Lukin J, Xu X, Skarina T, Evdokimova E, Liu CS, Semesi A, Guido V, Edwards AM, Arrowsmith CH,
Journal of the American Chemical Society (2005) 127(47):16512-7 PublishedPSI:Phase 2  
Midwest Center for Structural GenomicsNortheast Structural Genomics Consortium

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NMR spectroscopy and X-ray crystallography, the two primary experimental methods for protein structure determination at high resolution, have different advantages and disadvantages in terms of sample preparation and data collection and analysis. ...
chemistry methods 
Crystallography, X-Ray Magnetic Resonance Spectroscopy Animals Proteomics Proteins 
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