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Crystal structure of RlmAI: implications for understanding the 23S rRNA G745/G748-methylation at the macrolide antibiotic-binding site.

Das K, Acton T, Chiang Y, Shih L, Arnold E, Montelione GT,
Proceedings of the National Academy of Sciences of the United States of America (2004) 101(12):4041-6 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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The RlmA class of enzymes (RlmA(I) and RlmA(II)) catalyzes N1-methylation of a guanine base (G745 in Gram-negative and G748 in Gram-positive bacteria) of hairpin 35 of 23S rRNA. ...
metabolism chemistry enzymology 
Binding Sites Crystallography, X-Ray Protein Structure, Tertiary Amino Acid Sequence Molecular Sequence Data Escherichia coli Zinc RNA, Ribosomal, 23S S-Adenosylmethionine Methyltransferases Macrolides 
26 (Last update: 03/16/2019 6:03:08pm)  
Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4041-6. Epub 2004 Mar 3.