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Functional topology in a network of protein interactions.

Przulj N, Wigle DA, Jurisica I,
Bioinformatics (2004) 20(3):340-8 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Our models provide a means for understanding the complex wiring underlying cellular function, and enable us to predict essentiality, genetic interaction, function, protein complexes and cellular pathways. ...
metabolism methods physiology 
Algorithms Signal Transduction Models, Biological Multienzyme Complexes Saccharomyces cerevisiae Proteins Saccharomyces cerevisiae Computer Simulation Cluster Analysis Protein Interaction Mapping 
205 (Last update: 03/16/2019 8:52:43pm)  
Bioinformatics. 2004 Feb 12;20(3):340-8.