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Functional topology in a network of protein interactions.

Przulj N, Wigle DA, Jurisica I,
Bioinformatics (2004) 20(3):340-8 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Our models provide a means for understanding the complex wiring underlying cellular function, and enable us to predict essentiality, genetic interaction, function, protein complexes and cellular pathways. ...
physiology methods metabolism 
Models, Biological Signal Transduction Computer Simulation Saccharomyces cerevisiae Proteins Saccharomyces cerevisiae Cluster Analysis Multienzyme Complexes Protein Interaction Mapping Algorithms 
187 (Last update: 04/01/2017 12:07:04pm)  
Bioinformatics. 2004 Feb 12;20(3):340-8.