|Journal of Structural Biology (2003) 142(1):170-9|
|Structural Genomics of Pathogenic ProtozoaNortheast Structural Genomics Consortium|
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A method to rationally predict crystallization conditions for a previously uncrystallized macromolecule has not yet been developed. ...
One way around this problem is to determine initial crystallization conditions by casting a wide net, surveying a large number of chemical and physical conditions to locate crystallization leads. A facility that executes the rapid survey of crystallization lead conditions is described in detail. Results and guidelines for the initial screening of crystallization conditions, applicable to both manual and robotic setups, are discussed.
|methods isolation & purification instrumentation chemistry |
|Computers Crystallization Biopolymers Oils Software Automation |
|193 (Last update: 03/18/2017 12:16:44pm)|
High-throughput screening to identify initial crystallization conditions
|J Struct Biol. 2003 Apr;142(1):170-9.|