|Current Opinion in Chemical Biology (2003) 7:44-54|
|Northeast Structural Genomics Consortium|
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A principal aim of post-genomic biology is elucidating the structures, functions and biochemical properties of all gene products in a genome. ...
However, to adequately comprehend such a large amount of information we need new descriptions of proteins that scale to the genomic level. In short, we need a unified ontology for proteomics. Much progress has been made towards this end, including a variety of approaches to systematic structural and functional classification and initial work towards developing standardized, unified descriptions for protein properties. In relation to function, there is a particularly great diversity of approaches, involving placing a protein in structured hierarchies or more-generalized networks and a recent approach based on circumscribing a protein's function through systematic enumeration of molecular interactions.
|Computational Biology Information Management Databases, Protein Proteomics Genome Proteins Genes |
|38 (Last update: 03/25/2017 12:18:35pm)|
|Curr Opin Chem Biol. 2003 Feb;7(1):44-54.|