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Crystal structures of the BtuF periplasmic-binding protein for vitamin B12 suggest a functionally important reduction in protein mobility upon ligand binding.

Karpowich NK, Huang HH, Smith PC, Hunt JF,
Journal of Biological Chemistry (2003) 278(10):8429-34 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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BtuF is the periplasmic binding protein (PBP) for the vitamin B12 transporter BtuCD, a member of the ATP-binding cassette (ABC) transporter superfamily of transmembrane pumps. ...
chemistry metabolism 
Crystallography, X-Ray Models, Molecular Molecular Sequence Data Periplasmic Binding Proteins Protein Conformation Ligands Vitamin B 12 Amino Acid Sequence Protein Binding Sequence Homology, Amino Acid Escherichia coli Proteins 
111 (Last update: 04/21/2018 3:06:01pm)  
J Biol Chem. 2003 Mar 7;278(10):8429-34. Epub 2002 Dec 4.