View publication

Crystal structures of the BtuF periplasmic-binding protein for vitamin B12 suggest a functionally important reduction in protein mobility upon ligand binding.

Karpowich NK, Huang HH, Smith PC, Hunt JF,
Journal of Biological Chemistry (2003) 278(10):8429-34 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

(click to unfold)
BtuF is the periplasmic binding protein (PBP) for the vitamin B12 transporter BtuCD, a member of the ATP-binding cassette (ABC) transporter superfamily of transmembrane pumps. ...
metabolism chemistry 
Crystallography, X-Ray Amino Acid Sequence Models, Molecular Molecular Sequence Data Protein Binding Escherichia coli Proteins Protein Conformation Sequence Homology, Amino Acid Ligands Vitamin B 12 Periplasmic Binding Proteins 
113 (Last update: 03/16/2019 5:18:23pm)  
J Biol Chem. 2003 Mar 7;278(10):8429-34. Epub 2002 Dec 4.