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Crystal structures of the BtuF periplasmic-binding protein for vitamin B12 suggest a functionally important reduction in protein mobility upon ligand binding.

Karpowich NK, Huang HH, Smith PC, Hunt JF,
Journal of Biological Chemistry (2003) 278(10):8429-34 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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BtuF is the periplasmic binding protein (PBP) for the vitamin B12 transporter BtuCD, a member of the ATP-binding cassette (ABC) transporter superfamily of transmembrane pumps. ...
metabolism chemistry 
Crystallography, X-Ray Amino Acid Sequence Models, Molecular Molecular Sequence Data Protein Binding Escherichia coli Proteins Protein Conformation Sequence Homology, Amino Acid Ligands Vitamin B 12 Periplasmic Binding Proteins 
12468528  
10.1074/jbc.M212239200  
111 (Last update: 05/23/2018 8:33:37pm)  
1N4A
1N4D  
structure  
J Biol Chem. 2003 Mar 7;278(10):8429-34. Epub 2002 Dec 4.