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Enhancement of the solubility of proteins overexpressed in Escherichia coli by heat shock.

Chen J, Acton TB, Basu SK, Montelione GT, Inouye M,
Journal of Molecular Microbiology and Biotechnology (2002) 4(6):519-24 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Protein misfolding resulting in the formation of inclusion bodies is one of the major problems during protein overexpression in Escherichia coil. ...
metabolism chemistry methods genetics physiology 
Animals Escherichia coli Methyltransferases Solubility Caenorhabditis elegans Proteins Culture Media Biotechnology Heat-Shock Response 
32 (Last update: 03/16/2019 1:34:18pm)  
J Mol Microbiol Biotechnol. 2002 Nov;4(6):519-24.