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Loopy proteins appear conserved in evolution.

Liu J, Tan H, Rost B,
Journal of Molecular Biology (2002) 322:53-64 PublishedPSI:Phase 2  
Northeast Structural Genomics Consortium

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Over the last decade, structural biologists have unravelled many proteins that appear natively disordered. ...
analysis classification metabolism chemistry methods 
Computational Biology Models, Molecular Amino Acids Proteome Conserved Sequence Databases, Protein Structure-Activity Relationship Evolution, Molecular Transcription, Genetic Pliability Protein Folding Protein Structure, Secondary Proteins Protein Binding Hydrogen Bonding Solvents 
12215414  
10.1016/S0022-2836(02)00736-2  
140 (Last update: 05/27/2017 11:41:42am)  
method  
J Mol Biol. 2002 Sep 6;322(1):53-64.