Results of search for Ma
2018
- Classification, substrate specificity and structural features of D-2-hydroxyacid dehydrogenases: 2HADH knowledgebase.
MAtelska D, Shabalin IG, Jabłońska J, DoMAgalski MJ, Kutner J, Ginalski K, Minor W
CSGID, BMC evolutionary biology
(Details)(Pubmed ID: 30577795)
Times cited: 0
- A Gcn5-related N-acetyltransferase (GNAT) capable of acetylating polymyxin B and colistin antibiotics in vitro.
Czub MP, Zhang B, Chiarelli MP, MAjorek KA, Joe L, Porebski PJ, Revilla A, Wu W, Becker DP, Minor W, Kuhn ML
CSGID, Biochemistry
(Details)(Pubmed ID: 30499668)
Times cited: 0
- A close look onto structural models and priMAry ligands of metallo-β-lactaMAses.
Raczynska JE, Shabalin IG, Minor W, Wlodawer A, Jaskolski M
CSGID, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
(Details)(Pubmed ID: 30466711)
Times cited: 1
- Refining the MAcromolecular model - achieving the best agreement with the data from X-ray diffraction experiment.
Shabalin IG, Porebski PJ, Minor W
CSGID, Crystallography reviews
(Details)(Pubmed ID: 30416256)
Times cited: 1
- CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in ToxoplasMA gondii
Joseph D. Lykins, Ekaterina V. Filippova, Andrei S. Halavaty, George Minasov, Ying Zhou, Ievgeniia Dubrovska, Kristin J. Flores, Ludmilla A. Shuvalova, Jiapeng Ruan, KaMAl El Bissati, Sarah Dovgin, Craig W. Roberts, Stuart Woods, Jon D. Moulton, Hong Moulton, MArtin J. McPhillie, Stephen P. Muench, Colin W. G. Fishwick, Elisabetta Sabini, Dhanasekaran Shanmugam, David S. Roos, RiMA McLeod, Wayne F. Anderson, and Huân M. Ngô
CSGID, Frontiers in cellular and infection microbiology
(Details)(Pubmed ID: 30345257)
PDB ID(s): 4NML 4NOG 4ODI 5DJ9 5E3K 5E5I
Times cited: 0
- Functional diversification of the NleG effector family in enterohemorrhagic Escherichia coli
Valleau D, Little DJ, Borek D, Skarina T, Quaile AT, Di Leo R, Houliston S, LeMAk A, Arrowsmith CH, Coombes BK, Savchenko A
CSGID, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 30217892)
PDB ID(s): 5VGC
Times cited: 0
- Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Nelson CA, Wilen CB, Dai YN, Orchard RC, Kim AS, StegeMAn RA, Hsieh LL, Smith TJ, Virgin HW, Fremont DH
CSGID, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 30194229)
Times cited: 0
- AutoMAtic Recognition of Ligands in Electron Density by MAchine Learning.
Kowiel M, Brzezinski D, Porebski PJ, Shabalin IG, Jaskolski M, Minor W
CSGID, Bioinformatics
(Details)(Pubmed ID: 30016407)
Times cited: 1
- Structural Basis for DNA Recognition by the Two-Component Response Regulator RcsB.
Filippova EV, ZeMAitaitis B, Aung T, Wolfe AJ, Anderson WF
CSGID, mBio
(Details)(Pubmed ID: 29487239)
Times cited: 1
- Structural Basis of a Thiol-Disulfide Oxidoreductase in the Hedgehog-Forming Actinobacterium Corynebacterium MAtruchotii.
Luong TT, Tirgar R, Reardon-Robinson ME, Joachimiak A, Osipiuk J, Ton-That H
CSGID, Journal of Bacteriology
(Details)(Pubmed ID: 29440253)
Times cited: 0
- The evolution of substrate discrimination in MAcrolide antibiotic resistance enzymes.
Pawlowski AC, Stogios PJ, Koteva K, Skarina T, Evdokimova E, Savchenko A, Wright GD
CSGID, Nature communications
(Details)(Pubmed ID: 29317655)
PDB ID(s): 5IWU 5UXA 5UXB 5UXC 5UXD
Times cited: 4
- Structural Evidence of a MAjor ConforMAtional Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism.
Nocek B, Reidl C, Starus A, Heath T, Bienvenue D, Osipiuk J, Jedrzejczak R, Joachimiak A, Becker DP, Holz RC
CSGID, Biochemistry
(Details)(Pubmed ID: 29272107)
PDB ID(s): 5VOE
Times cited: 1
- Molstack-Interactive visualization tool for presentation, interpretation, and validation of MAcromolecules and electron density MAps.
Porebski PJ, Sroka P, Zheng H, Cooper DR, Minor W
CSGID, Protein Science
(Details)(Pubmed ID: 28815771)
Times cited: 7
2017
- ToxoplasMA Modulates Signature Pathways of HuMAn Epilepsy, Neurodegeneration & Cancer.
Ngô HM, Zhou Y, Lorenzi H, Wang K, Kim TK, Zhou Y, El Bissati K, Mui E, Fraczek L, Rajagopala SV, Roberts CW, Henriquez FL, Montpetit A, Blackwell JM, Jamieson SE, Wheeler K, BegeMAn IJ, Naranjo-Galvis C, Alliey-Rodriguez N, Davis RG, Soroceanu L, Cobbs C, Steindler DA, Boyer K, Noble AG, Swisher CN, HeydeMAnn PT, Rabiah P, Withers S, Soteropoulos P, Hood L, McLeod R
CSGID, Scientific reports
(Details)(Pubmed ID: 28904337)
Times cited: 9
- Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.
Reidl C, MAjorek KA, Dang J, Tran D, Jew K, Law M, Payne Y, Minor W, Becker DP, Kuhn ML
CSGID+MCSG, FEBS Letters
(Details)(Pubmed ID: 28703494)
Times cited: 0
- A sMAll-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.
Wellington S, Nag PP, Michalska K, Johnston SE, Jedrzejczak RP, Kaushik VK, Clatworthy AE, Siddiqi N, McCarren P, Bajrami B, MAltseva NI, Combs S, Fisher SL, Joachimiak A, Schreiber SL, Hung DT
CSGID, Nature Chemical Biology
(Details)(Pubmed ID: 28671682)
PDB ID(s): 5TCF 5TCG 5TCH 5TCI 5TCJ
Times cited: 23
- Insights into PG-binding, conforMAtional change, and dimerization of the OmpA C-terminal doMAins from Salmonella enterica serovar Typhimurium and Borrelia burgdorferi.
Tan K, Deatherage Kaiser BL, Wu R, Cuff M, Fan Y, Bigelow L, Jedrzejczak RP, Adkins JN, Cort JR, Babnigg G, Joachimiak A
CSGID, Protein Science
(Details)(Pubmed ID: 28580643)
Times cited: 1
- Data mining of iron(II) and iron(III) bond-valence parameters, and their relevance for MAcromolecular crystallography.
Zheng H, Langner KM, Shields GP, Hou J, Kowiel M, Allen FH, Murshudov G, Minor W
CSGID, Acta crystallographica. Section D, Structural biology
(Details)(Pubmed ID: 28375143)
Times cited: 4
- CheckMyMetal: a MAcromolecular metal-binding validation tool.
Zheng H, Cooper DR, Porebski PJ, Shabalin IG, Handing KB, Minor W
CSGID, Acta crystallographica. Section D, Structural biology
(Details)(Pubmed ID: 28291757)
Times cited: 34
- Novel Aldo-Keto Reductases for the Biocatalytic Conversion of 3-Hydroxybutanal to 1,3-Butanediol: Structural and Biochemical Studies.
Kim T, Flick R, Brunzelle J, Singer A, Evdokimova E, Brown G, Joo JC, Minasov GA, Anderson WF, MAhadevan R, Savchenko A, Yakunin AF
CSGID, Applied and environmental microbiology
(Details)(Pubmed ID: 28130301)
PDB ID(s): 3ERP 5T79
Times cited: 2
- Transferase Versus Hydrolase: The Role of ConforMAtional Flexibility in Reaction Specificity.
Light SH, Cahoon LA, MAhasenan KV, Lee M, Boggess B, Halavaty AS, Mobashery S, Freitag NE, Anderson WF
CSGID, Structure
(Details)(Pubmed ID: 28089449)
PDB ID(s): 5HPO 5HXM 5I0D 5I0E 5I0F 5I0G
Times cited: 3
- Identification of novel sMAll molecule inhibitors against NS2B/NS3 serine protease from Zika virus.
Lee H, Ren J, Nocadello S, Rice AJ, Ojeda I, Light S, Minasov G, Vargas J, Nagarathnam D, Anderson WF, Johnson ME
CSGID, Antiviral research
(Details)(Pubmed ID: 28034741)
Times cited: 38
2016
- A public database of MAcromolecular diffraction experiments.
Grabowski M, Langner KM, Cymborowski M, Porebski PJ, Sroka P, Zheng H, Cooper DR, ZimmerMAn MD, Elsliger MA, Burley SK, Minor W
CSGID, Acta crystallographica. Section D, Structural biology
(Details)(Pubmed ID: 27841751)
Times cited: 25
- Neutralizing huMAn antibodies prevent Zika virus replication and fetal disease in mice.
Sapparapu G, Fernandez E, Kose N, Cao B, Fox JM, Bombardi RG, Zhao HY, Nelson CA, Bryan AL, Barnes T, Davidson E, Mysorekar IU, Fremont DH, Doranz BJ, Diamond MS, Crowe JE
CSGID, Nature
(Details)(Pubmed ID: 27819683)
Times cited: 142
- Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria.
MAjorek KA, Osinski T, Tran DT, Revilla A, Anderson WF, Minor W, Kuhn ML
CSGID, Biochimica et biophysica acta
(Details)(Pubmed ID: 27783928)
Times cited: 3
- AroMAtic Claw: A new fold with high aroMAtic content that evades structural prediction.
Sachleben JR, Adhikari AN, Gawlak G, Hoey RJ, Liu G, Joachimiak A, Montelione GT, Sosnick TR, Koide S
NESG, Protein Science
(Details)(Pubmed ID: 27750371)
Times cited: 0
- Crystal structure of nonphosphorylated receiver doMAin of the stress response regulator RcsB from Escherichia coli.
Filippova EV, Wawrzak Z, Ruan J, Pshenychnyi S, Schultz RM, Wolfe AJ, Anderson WF
CSGID, Protein Science
(Details)(Pubmed ID: 27670836)
PDB ID(s): 5I4C
Times cited: 6
- Selective targeting of IL-2 to NKG2D bearing cells for improved immunotherapy.
Ghasemi R, Lazear E, Wang X, Arefanian S, Zheleznyak A, Carreno BM, Higashikubo R, GelMAn AE, Kreisel D, Fremont DH, Krupnick AS
CSGID, Nature communications
(Details)(Pubmed ID: 27650575)
Times cited: 11
- Structural Basis of Zika Virus-Specific Antibody Protection.
Zhao H, Fernandez E, Dowd KA, Speer SD, Platt DJ, GorMAn MJ, Govero J, Nelson CA, Pierson TC, Diamond MS, Fremont DH
CSGID, Cell
(Details)(Pubmed ID: 27475895)
PDB ID(s): 5KVG 5KVF 5KVD
Times cited: 143
- Design of structurally distinct proteins using strategies inspired by evolution.
Jacobs TM, Williams B, Williams T, Xu X, Eletsky A, Federizon JF, Szyperski T, KuhlMAn B
NESG, Science
(Details)(Pubmed ID: 27151863)
Times cited: 37
- Crystal structures of the transpeptidase doMAin of the Mycobacterium tuberculosis penicillin-binding protein PonA1 reveal potential mechanisms of antibiotic resistance.
Filippova EV, Kieser KJ, Luan CH, Wawrzak Z, Kiryukhina O, Rubin EJ, Anderson WF
CSGID+MCSG, FEBS Journal
(Details)(Pubmed ID: 27101811)
Times cited: 6
- Fluorescence-based therMAl shift data on multidrug regulator AcrR from Salmonella enterica subsp. entrica serovar Typhimurium str. LT2.
MAnjasetty BA, Halavaty AS, Luan CH, Osipiuk J, Mulligan R, Kwon K, Anderson WF, Joachimiak A
CSGID, Data in brief
(Details)(Pubmed ID: 27054155)
Times cited: 0
- Outcome of the First wwPDB/CCDC/D3R Ligand Validation Workshop.
Adams PD, Aertgeerts K, Bauer C, Bell JA, BerMAn HM, Bhat TN, Blaney JM, Bolton E, Bricogne G, Brown D, Burley SK, Case DA, Clark KL, Darden T, Emsley P, Feher VA, Feng Z, Groom CR, Harris SF, Hendle J, Holder T, Joachimiak A, Kleywegt GJ, Krojer T, MArcotrigiano J, MArk AE, MArkley JL, Miller M, Minor W, Montelione GT, Murshudov G, Nakagawa A, Nakamura H, Nicholls A, Nicklaus M, Nolte RT, Padyana AK, Peishoff CE, Pieniazek S, Read RJ, Shao C, Sheriff S, SMArt O, Soisson S, Spurlino J, Stouch T, Svobodova R, Tempel W, Terwilliger TC, Tronrud D, Velankar S, Ward SC, Warren GL, Westbrook JD, Williams P, Yang H, Young J
NESG, Structure
(Details)(Pubmed ID: 27050687)
Times cited: 25
- The impact of structural genomics: the first quindecennial.
Grabowski M, Niedzialkowska E, ZimmerMAn MD, Minor W
CSGID, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 26935210)
Times cited: 16
- DIx5 HomeodoMAin:DNA Complex: Structure, Binding and Effect of Mutations Related to Split Hand and Foot MAlforMAtion Syndrome
Proudfoot A, Axelrod HL, Geralt M, Fletterick RJ, Yumoto F, Deacon AM, Elsliger MA, Wilson IA, Wüthrich K, Serrano P
JCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 26829219)
PDB ID(s): 4RDU
Times cited: 2
- An Unusual Cation-Binding Site and Distinct DoMAin-DoMAin Interactions Distinguish Class II EnolpyruvylshikiMAte-3-Phosphate Synthases.
Light SH, Krishna SN, Minasov G, Anderson WF
CSGID, Biochemistry
(Details)(Pubmed ID: 26813771)
PDB ID(s): 3NVS 3ROI 3SLH 4ZND 4GFP
Times cited: 3
- Loop-to-helix transition in the structure of multidrug regulator AcrR at the entrance of the drug-binding cavity.
MAnjasetty BA, Halavaty AS, Luan CH, Osipiuk J, Mulligan R, Kwon K, Anderson WF, Joachimiak A
CSGID, Journal of Structural Biology
(Details)(Pubmed ID: 26796657)
PDB ID(s): 3LHQ
Times cited: 3
- SMAll angle X-ray scattering data and structure factor fitting for the study of the quaternary structure of the spermidine N-acetyltransferase SpeG.
Weigand S, Filippova EV, Kiryukhina O, Anderson WF
CSGID, Data in brief
(Details)(Pubmed ID: 26793756)
Times cited: 0
- Nuclear MAgnetic Resonance Structure of a Novel Globular DoMAin in RBM10 Containing OCRE, the Octamer Repeat Sequence Motif.
MArtin BT, Serrano P, Geralt M, Wüthrich K
JCSG, Structure
(Details)(Pubmed ID: 26712279)
PDB ID(s): 2MXW
Times cited: 5
- Protein purification and crystallization artifacts: The tale usually not told.
Niedzialkowska E, Gasiorowska O, Handing KB, MAjorek KA, Porebski PJ, Shabalin IG, Zasadzinska E, Cymborowski M, Minor W
CSGID, Protein Science
(Details)(Pubmed ID: 26660914)
Times cited: 10
- A community resource of experimental data for NMR / X-ray crystal structure pairs.
Everett JK, Tejero R, Murthy SB, Acton TB, Aramini JM, Baran MC, Benach J, Cort JR, Eletsky A, Forouhar F, Guan R, Kuzin AP, Lee HW, Liu G, MAni R, MAo B, Mills JL, Montelione AF, Pederson K, Powers R, Ramelot T, Rossi P, SeetharaMAn J, Snyder D, Swapna GV, Vorobiev SM, Wu Y, Xiao R, Yang Y, Arrowsmith CH, Hunt JF, Kennedy MA, Prestegard JH, Szyperski T, Tong L, Montelione GT
NESG, Protein Science
(Details)(Pubmed ID: 26293815)
Times cited: 4
2015
- Structure and Functional Characterization of a Bile Acid 7α Dehydratase BaiE in Secondary Bile Acid Synthesis.
Bhowmik S, Chiu HP, Jones DH, Chiu HJ, Miller MD, Xu Q, Farr CL, Ridlon JM, Wells JE, Elsliger MA, Wilson IA, Hylemon PB, Lesley SA
JCSG, Proteins
(Details)(Pubmed ID: 26650892)
PDB ID(s): 4L8P 4L8O 4LEH 4N3V
Times cited: 9
- Precise assembly of complex beta sheet topologies from de novo designed building blocks.
King IC, Gleixner J, Doyle L, Kuzin A, Hunt JF, Xiao R, Montelione GT, Stoddard BL, DiMAio F, Baker D
NESG, eLife
(Details)(Pubmed ID: 26650357)
Times cited: 5
- Dissecting the Structural Elements for the Activation of β-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
Hou J, Zheng H, Chruszcz M, ZimmerMAn MD, Shumilin IA, Osinski T, DeMAs M, Grimshaw S, Minor W
CSGID, Journal of Bacteriology
(Details)(Pubmed ID: 26553852)
Times cited: 6
- Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds.
MAkowska-Grzyska M, Kim Y, Gorla SK, Wei Y, MAndapati K, Zhang M, MAltseva N, Modi G, Boshoff HI, Gu M, Aldrich C, Cuny GD, Hedstrom L, Joachimiak A
CSGID, PLoS ONE
(Details)(Pubmed ID: 26440283)
PDB ID(s): 4ZQM 4ZQN 4ZQO 4ZQP 4ZQR
Times cited: 10
- A novel transcriptional regulator of L-arabinose utilization in huMAn gut bacteria.
Chang C, Tesar C, Li X, Kim Y, Rodionov DA, Joachimiak A
MCSG, Nucleic Acids Research
(Details)(Pubmed ID: 26438537)
PDB ID(s): 5BS6 5DD4 5DDG 5DEQ
Times cited: 6
- MApping the conforMAtional landscape of a dynamic enzyme by multitemperature and XFEL crystallography.
Keedy DA, Kenner LR, Warkentin M, Woldeyes RA, Hopkins JB, Thompson MC, Brewster AS, Van Benschoten AH, Baxter EL, Uervirojnangkoorn M, McPhillips SE, Song J, Alonso-Mori R, Holton JM, Weis WI, Brunger AT, Soltis SM, Lemke H, Gonzalez A, Sauter NK, Cohen AE, van den Bedem H, Thorne RE, Fraser JS
JCSG, eLife
(Details)(Pubmed ID: 26422513)
Times cited: 39
- Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
LohMAn JR, MA M, Osipiuk J, Nocek B, Kim Y, Chang C, Cuff M, MAck J, Bigelow L, Li H, Endres M, Babnigg G, Joachimiak A, Phillips GN, Shen B
MCSG+NatPro, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 26420866)
PDB ID(s): 4QYR 4ZDN 4TKT 4OQJ 4WKY 4OPE 4OPF
Times cited: 21
- Engineering of KuMA030: A Gliadin Peptidase That Rapidly Degrades Immunogenic Gliadin Peptides in Gastric Conditions.
Wolf C, Siegel JB, Tinberg C, CaMArca A, Gianfrani C, Paski S, Guan R, Montelione G, Baker D, Pultz IS
NESG, Journal of the American Chemical Society
(Details)(Pubmed ID: 26374198)
Times cited: 15
- Insights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 DoMAins.
Xu Q, Mengin-Lecreulx D, Liu XW, Patin D, Farr CL, Grant JC, Chiu HJ, Jaroszewski L, Knuth MW, Godzik A, Lesley SA, Elsliger MA, Deacon AM, Wilson IA
JCSG, mBio
(Details)(Pubmed ID: 26374125)
PDB ID(s): 3M1U 3NPF 3PVQ 4R0K
Times cited: 6
- Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) DoMAin Superfamily.
Nelson CA, Epperson ML, Singh S, Elliott JI, Fremont DH
CSGID, Viruses
(Details)(Pubmed ID: 26343707)
Times cited: 10
- Structural and Functional Adaptation of Vancomycin Resistance VanT Serine RaceMAses.
Meziane-Cherif D, Stogios PJ, Evdokimova E, Egorova O, Savchenko A, Courvalin P
CSGID, mBio
(Details)(Pubmed ID: 26265719)
PDB ID(s): 4ECL
Times cited: 4
- EstiMAtion of Hydrogen-Exchange Protection Factors from MD Simulation Based on Amide Hydrogen Bonding Analysis.
Park IH, Venable JD, Steckler C, Cellitti SE, Lesley SA, Spraggon G, Brock A
JCSG, Journal of chemical information and modeling
(Details)(Pubmed ID: 26241692)
Times cited: 11
- Structural Characterization of CalS8, a TDP-alpha-D-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose Biosynthesis.
Singh S, Michalska K, Bigelow L, Endres M, Kharel MK, Babnigg G, YennaMAlli RM, BingMAn CA, Joachimiak A, Thorson JS, Phillips GN
MCSG+NatPro, Journal of Biological Chemistry
(Details)(Pubmed ID: 26240141)
PDB ID(s): 4XRR 4XR9
Times cited: 1
- Non-Uniform Sampling and J-UNIO AutoMAtion for Efficient Protein NMR Structure Determination.
Didenko T, Proudfoot A, Dutta SK, Serrano P, Wüthrich K
JCSG, Chemistry (Weinheim an der Bergstrasse, Germany)
(Details)(Pubmed ID: 26227870)
Times cited: 3
- Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, MA J, Zhi X, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter CS, Carragher B, Caffrey M, Jiang H, ChapMAn HN, Spence JC, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE
GPCR+JCSG, Nature
(Details)(Pubmed ID: 26200343)
PDB ID(s): 4ZWJ
Times cited: 289
- Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril.
Starus A, Nocek B, Bennett B, Larrabee JA, Shaw DL, Sae-Lee W, Russo MT, Gillner DM, MAkowska-Grzyska M, Joachimiak A, Holz RC
CSGID, Biochemistry
(Details)(Pubmed ID: 26186504)
PDB ID(s): 4PPZ 4PPQ 4O23
Times cited: 5
- Cofactor-induced reversible folding of Flavodoxin-4 from Lactobacillus acidophilus.
Dutta SK, Serrano P, Geralt M, Axelrod HL, Xu Q, Lesley SA, Godzik A, Deacon AM, Elsliger MA, Wilson IA, Wüthrich K
JCSG, Protein Science
(Details)(Pubmed ID: 26177955)
PDB ID(s): 2MWM 3EDO 2N1M
Times cited: 0
- X-ray crystallography over the past decade for novel drug discovery - where are we heading next?
Zheng H, Handing KB, ZimmerMAn MD, Shabalin IG, Almo SC, Minor W
CSGID, Expert opinion on drug discovery
(Details)(Pubmed ID: 26177814)
Times cited: 21
- The RAS-Binding DoMAin of HuMAn BRAF Protein Serine/Threonine Kinase Exhibits Allosteric ConforMAtional Changes upon Binding HRAS.
Aramini JM, Vorobiev SM, Tuberty LM, Janjua H, Campbell ET, SeetharaMAn J, Su M, Huang YJ, Acton TB, Xiao R, Tong L, Montelione GT
NESG, Structure
(Details)(Pubmed ID: 26165597)
Times cited: 7
- Identification of Salmonella Typhimurium Deubiquitinase SseL Substrates by Immunoaffinity Enrichment and Quantitative Proteomic Analysis.
Nakayasu ES, Sydor MA, Brown RN, Sontag RL, Sobreira TJ, Slysz GW, Humphrys DR, Skarina T, Onoprienko O, Di Leo R, Deatherage Kaiser BL, Li J, Ansong C, Cambronne ED, Smith RD, Savchenko A, Adkins JN
MCSG+PCSEP, Journal of proteome research
(Details)(Pubmed ID: 26147956)
Times cited: 3
- Protein structure determination by combining sparse NMR data with evolutionary couplings.
Tang Y, Huang YJ, Hopf TA, Sander C, MArks DS, Montelione GT
NESG, Nature Methods
(Details)(Pubmed ID: 26121406)
Times cited: 26
- Structural and Functional Analysis of HuMAn HtrA3 Protease and Its SubdoMAins.
Glaza P, Osipiuk J, Wenta T, Zurawa-Janicka D, Jarzab M, Lesner A, Banecki B, Skorko-Glonek J, Joachimiak A, Lipinska B
MCSG, PLoS ONE
(Details)(Pubmed ID: 26110759)
PDB ID(s): 4RI0
Times cited: 12
- Aspirin's Active Metabolite Salicylic Acid Targets High Mobility Group Box 1 to Modulate InflamMAtory Responses.
Choi HW, Tian M, Song F, Venereau E, Preti A, Park SW, Hamilton K, Swapna GV, MAnohar M, Moreau M, Agresti A, Gorzanelli A, De MArchis F, Wang H, Antonyak M, Micikas RJ, Gentile DR, Cerione RA, Schroeder FC, Montelione GT, Bianchi ME, Klessig DF
NESG, Molecular medicine (Cambridge, Mass.)
(Details)(Pubmed ID: 26101955)
Times cited: 31
- Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop.
Sali A, BerMAn HM, Schwede T, Trewhella J, Kleywegt G, Burley SK, MArkley J, Nakamura H, Adams P, Bonvin AM, Chiu W, Peraro MD, Di MAio F, Ferrin TE, Grünewald K, GutMAnas A, Henderson R, Hummer G, Iwasaki K, Johnson G, Lawson CL, Meiler J, MArti-Renom MA, Montelione GT, Nilges M, Nussinov R, Patwardhan A, Rappsilber J, Read RJ, Saibil H, Schröder GF, Schwieters CD, Seidel CA, Svergun D, Topf M, Ulrich EL, Velankar S, Westbrook JD
NESG, Structure
(Details)(Pubmed ID: 26095030)
Times cited: 64
- Guiding autoMAted NMR structure determination using a global optimization metric, the NMR DP score.
Huang YJ, MAo B, Xu F, Montelione GT
NESG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 26081575)
Times cited: 2
- The second round of Critical Assessment of AutoMAted Structure Determination of Proteins by NMR: CASD-NMR-2013.
Rosato A, Vranken W, Fogh RH, Ragan TJ, Tejero R, Pederson K, Lee HW, Prestegard JH, Yee A, Wu B, LeMAk A, Houliston S, Arrowsmith CH, Kennedy M, Acton TB, Xiao R, Liu G, Montelione GT, Vuister GW
NESG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 26071966)
Times cited: 11
- Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: Biochemical, Structural, and Evolutionary Insights.
Kuznetsova E, Nocek B, Brown G, MAkarova KS, Flick R, Wolf YI, Khusnutdinova A, Evdokimova E, Jin K, Tan K, Hanson AD, Hasnain G, Zallot R, de Crecy-Lagard V, Babu M, Savchenko A, Joachimiak A, Edwards AM, Koonin EV, Yakunin AF
MCSG, Journal of Biological Chemistry
(Details)(Pubmed ID: 26071590)
PDB ID(s): 2QLT 3KC2 3RF6
Times cited: 24
- New aminopeptidase from "microbial dark MAtter" archaeon.
Michalska K, Steen AD, Chhor G, Endres M, Webber AT, Bird J, Lloyd KG, Joachimiak A
MCSG, FASEB Journal
(Details)(Pubmed ID: 26062601)
PDB ID(s): 4PF1
Times cited: 3
- Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis.
Singh S, Kim Y, Wang F, Bigelow L, Endres M, Kharel MK, Babnigg G, BingMAn CA, Joachimiak A, Thorson JS, Phillips GN
MCSG+NatPro, Proteins
(Details)(Pubmed ID: 26061967)
PDB ID(s): 4RXK
Times cited: 5
- NMR Exchange ForMAt: a unified and open standard for representation of NMR restraint data.
GutMAnas A, Adams PD, Bardiaux B, BerMAn HM, Case DA, Fogh RH, Güntert P, Hendrickx PM, HerrMAnn T, Kleywegt GJ, Kobayashi N, Lange OF, MArkley JL, Montelione GT, Nilges M, Ragan TJ, Schwieters CD, Tejero R, Ulrich EL, Velankar S, Vranken WF, Wedell JR, Westbrook J, Wishart DS, Vuister GW
NESG, Nature Structural & Molecular Biology
(Details)(Pubmed ID: 26036565)
Times cited: 9
- Structures of huMAn phosphofructokinase-1 and atomic basis of cancer-associated mutations.
Webb BA, Forouhar F, Szu FE, SeetharaMAn J, Tong L, Barber DL
NESG, Nature
(Details)(Pubmed ID: 25985179)
PDB ID(s): 3O8L 4PFK 6PFK 4XYJ 4XYK
Times cited: 26
- Structural and sequencing analysis of local target DNA recognition by MLV integrase.
Aiyer S, Rossi P, MAlani N, Schneider WM, Chandar A, BushMAn FD, Montelione GT, Roth MJ
NESG, Nucleic Acids Research
(Details)(Pubmed ID: 25969444)
Times cited: 8
- Structure of Cryptosporidium IMP dehydrogenase bound to an inhibitor with in vivo antiparasitic activity.
Kim Y, MAkowska-Grzyska M, Gorla SK, Gollapalli DR, Cuny GD, Joachimiak A, Hedstrom L
CSGID, Acta crystallographica. Section F, Structural biology communications
(Details)(Pubmed ID: 25945705)
PDB ID(s): 4RV8
Times cited: 5
- An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions.
Leung DW, Borek D, Luthra P, Binning JM, AnantpadMA M, Liu G, Harvey IB, Su Z, Endlich-Frazier A, Pan J, ShabMAn RS, Chiu W, Davey RA, Otwinowski Z, Basler CF, AMArasinghe GK
CSGID, Cell reports
(Details)(Pubmed ID: 25865894)
PDB ID(s): 4YPI
Times cited: 50
- Crystal Structure of a Two-Subunit TrkA Octameric Gating Ring Assembly.
Deller MC, Johnson HA, Miller MD, Spraggon G, Elsliger MA, Wilson IA, Lesley SA
JCSG, PLoS ONE
(Details)(Pubmed ID: 25826626)
PDB ID(s): 3L4B 2G1U 3JXO
Times cited: 0
- Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells.
Hayashi Y, Caboni L, Das D, Yumoto F, Clayton T, Deller MC, Nguyen P, Farr CL, Chiu HJ, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Tomoda K, Conklin BR, Wilson IA, YaMAnaka S, Fletterick RJ
JCSG+STEMCELL, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 25825768)
PDB ID(s): 4RBO
Times cited: 12
- MAgnesium-binding architectures in RNA crystal structures: validation, binding preferences, classification and motif detection.
Zheng H, Shabalin IG, Handing KB, Bujnicki JM, Minor W
CSGID+EFI+MCSG+NYSGRC, Nucleic Acids Research
(Details)(Pubmed ID: 25800744)
Times cited: 32
- The structure of bradyzoite-specific enolase from ToxoplasMA gondii reveals insights into its dual cytoplasmic and nuclear functions.
Ruan J, Mouveaux T, Light SH, Minasov G, Anderson WF, ToMAvo S, Ngô HM
CSGID, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 25760592)
PDB ID(s): 3OTR
Times cited: 10
- A novel polyamine allosteric site of SpeG from Vibrio cholerae is revealed by its dodecameric structure.
Filippova EV, Kuhn ML, Osipiuk J, Kiryukhina O, Joachimiak A, Ballicora MA, Anderson WF
CSGID, Journal of Molecular Biology
(Details)(Pubmed ID: 25623305)
Times cited: 10
- Identification and characterization of carboxyl esterases of gill chamber-associated microbiota in the deep-sea shrimp Rimicaris exoculata by using functional metagenomics.
Alcaide M, Tchigvintsev A, MArtínez-MArtínez M, Popovic A, Reva ON, Lafraya Á, Bargiela R, Nechitaylo TY, MAtesanz R, Cambon-Bonavita MA, Jebbar M, Yakimov MM, Savchenko A, Golyshina OV, Yakunin AF, Golyshin PN, Ferrer M
MCSG, Applied and environmental microbiology
(Details)(Pubmed ID: 25595762)
Times cited: 10
- Structure and sequence analyses of Bacteroides proteins BVU_4064 and BF1687 reveal presence of two novel predominantly-beta doMAins, predicted to be involved in lipid and cell surface interactions.
Natarajan P, Punta M, KuMAr A, Yeh AP, Godzik A, L A
JCSG, BMC Bioinformatics
(Details)(Pubmed ID: 25592227)
PDB ID(s): 3KOG 3G3L
Times cited: 2
- A Novel Cofactor-binding Mode in Bacterial IMP Dehydrogenases Explains Inhibitor Selectivity
MAgdalena MAkowska-Grzyska, Youngchang Kim, Natalia MAltseva, Jerzy Osipiuk, Minyi Gu, Minjia Zhang, Kavitha MAndapati, Deviprasad R. Gollapalli, Suresh KuMAr Gorla, Lizbeth Hedstrom, Andrzej Joachimiak
CSGID, Journal of Biological Chemistry
(Details)(Pubmed ID: 25572472)
PDB ID(s): 4MJM 4MY1 4MY8 4MY9 4MYA 4MYX 4MZ1 4MZ8 4Q32 4Q33 4QM1 4QNE 4X3Z
Times cited: 15
- A Novel Phosphatidylinositol 4,5-Bisphosphate Binding DoMAin Mediates PlasMA Membrane Localization of ExoU and Other Patatin-like Phospholipases.
Tyson GH, Halavaty AS, Kim H, Geissler B, Agard M, Satchell KJ, Cho W, Anderson WF, Hauser AR
CSGID, Journal of Biological Chemistry
(Details)(Pubmed ID: 25505182)
PDB ID(s): 4QMK
Times cited: 12
- Mitochondrial ADCK3 Employs an Atypical Protein Kinase-like Fold to Enable Coenzyme Q Biosynthesis.
Stefely JA, Reidenbach AG, Ulbrich A, Oruganty K, Floyd BJ, Jochem A, Saunders JM, Johnson IE, Minogue CE, Wrobel RL, Barber GE, Lee D, Li S, Kannan N, Coon JJ, BingMAn CA, Pagliarini DJ
MPP, Molecular Cell
(Details)(Pubmed ID: 25498144)
PDB ID(s): 4PED
Times cited: 28
- Sparse and incomplete factorial MAtrices to screen membrane protein 2D crystallization.
Lasala R, Coudray N, Abdine A, Zhang Z, Lopez-Redondo M, Kirshenbaum R, Alexopoulos J, Zolnai Z, Stokes DL, Ubarretxena-Belandia I
TEMIMPS, Journal of Structural Biology
(Details)(Pubmed ID: 25478971)
Times cited: 9
- A general computational approach for repeat protein design.
Parmeggiani F, Huang PS, Vorobiev S, Xiao R, Park K, Caprari S, Su M, SeetharaMAn J, MAo L, Janjua H, Montelione GT, Hunt J, Baker D
NESG, Journal of Molecular Biology
(Details)(Pubmed ID: 25451037)
Times cited: 42
- Multiple histidines in the periplasmic doMAin of the Salmonella enterica sensor kinase SsrA enhance signaling in response to extracellular acidification.
Mulder DT, McPhee JB, Reid-Yu SA, Stogios PJ, Savchenko A, Coombes BK
CSGID, Molecular Microbiology
(Details)(Pubmed ID: 25442048)
Times cited: 12
- APSY-NMR for protein backbone assignment in high-throughput structural biology.
Dutta SK, Serrano P, Proudfoot A, Geralt M, Pedrini B, HerrMAnn T, Wüthrich K
JCSG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 25428764)
Times cited: 15
- Structure and function of a single-chain, multi-doMAin long-chain acyl-CoA carboxylase.
Tran TH, Hsiao YS, Jo J, Chou CY, Dietrich LE, Walz T, Tong L
NESG, Nature
(Details)(Pubmed ID: 25383525)
Times cited: 11
- Structure of a cupin protein Plu4264 from Photorhabdus luminescens subsp. laumondii TTO1 at 1.35 Å resolution.
Weerth RS, Michalska K, BingMAn CA, YennaMAlli RM, Li H, Jedrzejczak R, Wang F, Babnigg G, Joachimiak A, ThoMAs MG, Phillips GN
MCSG+NatPro, Proteins
(Details)(Pubmed ID: 25354690)
PDB ID(s): 4MV2 4I4A
Times cited: 2
- Computational de novo design of a four-helix bundle protein--DND_4HB.
Murphy GS, Sathyamoorthy B, Der BS, MAchius MC, Pulavarti SV, Szyperski T, KuhlMAn B
NESG, Protein Science
(Details)(Pubmed ID: 25287625)
PDB ID(s): 21SE 1RJ1 2QSB 2ZRR
Times cited: 10
2014
- Correction to The Specialized Hsp70 (HscA) InterdoMAin Linker Binds to Its Nucleotide-Binding DoMAin and Stimulates ATP Hydrolysis in Both cis and trans Configurations.
Alderson TR, Kim JH, Cai K, Frederick RO, Tonelli M, MArkley JL
MPP, Biochemistry
(Details)(Pubmed ID: 25495500)
Times cited: 0
- Synthesis, in vitro evaluation and cocrystal structure of 4-oxo-[1]benzopyrano[4,3-c]pyrazole Cryptosporidium parvum inosine 5''-monophosphate dehydrogenase (CpIMPDH) inhibitors.
Sun Z, Khan J, MAkowska-Grzyska M, Zhang M, Cho JH, Suebsuwong C, Vo P, Gollapalli DR, Kim Y, Joachimiak A, Hedstrom L, Cuny GD
CSGID, Journal of Medicinal Chemistry
(Details)(Pubmed ID: 25474504)
PDB ID(s): 4QJ1
Times cited: 15
- Structure of the F-actin--tropomyosin complex.
von der Ecken J, Müller M, LehMAn W, MAnstein DJ, Penczek PA, Raunser S
TEMIMPS, Nature
(Details)(Pubmed ID: 25470062)
PDB ID(s): 3J8A
Times cited: 126
- Structure-Guided Functional Characterization of DUF1460 Reveals a Highly Specific NlpC/P60 Amidase Family.
Xu Q, Mengin-Lecreulx D, Patin D, Grant JC, Chiu HJ, Jaroszewski L, Knuth MW, Godzik A, Lesley SA, Elsliger MA, Deacon AM, Wilson IA
JCSG, Structure
(Details)(Pubmed ID: 25465128)
PDB ID(s): 4H4J 4Q68 4Q5K
Times cited: 4
- Structural characterization of a flexible two-doMAin protein in solution using sMAll angle X-ray scattering and NMR data.
LeMAk A, Wu B, Yee A, Houliston S, Lee HW, GutMAnas A, Fang X, Garcia M, Semesi A, Wang YX, Prestegard JH, Arrowsmith CH
NESG, Structure
(Details)(Pubmed ID: 25456817)
Times cited: 2
- Tangled web of interactions among proteins involved in iron-sulfur cluster assembly as unraveled by NMR, SAXS, chemical crosslinking, and functional studies.
Kim JH, Bothe JR, Alderson TR, MArkley JL
MPP, Biochimica et biophysica acta
(Details)(Pubmed ID: 25450980)
Times cited: 22
- The E. coli sirtuin CobB shows no preference for enzyMAtic and nonenzyMAtic lysine acetylation substrate sites.
AbouElfetouh A, Kuhn ML, Hu LI, Scholle MD, Sorensen DJ, Sahu AK, Becher D, AntelMAnn H, Mrksich M, Anderson WF, Gibson BW, Schilling B, Wolfe AJ
CSGID, MicrobiologyOpen
(Details)(Pubmed ID: 25417765)
Times cited: 39
- Specialized Hsp70 (HscA) interdoMAin linker binds to its nucleotide-binding doMAin and stimulates ATP hydrolysis in both cis and trans configurations.
Alderson TR, Kim JH, Cai K, Frederick RO, Tonelli M, MArkley JL
MPP, Biochemistry
(Details)(Pubmed ID: 25372495)
Times cited: 8
- Cell Fate Regulation Governed by a Repurposed Bacterial Histidine Kinase.
Childers WS, Xu Q, MAnn TH, MAthews II, Blair JA, Deacon AM, Shapiro L
JCSG, PLoS Biology
(Details)(Pubmed ID: 25349992)
PDB ID(s): 4Q20
Times cited: 25
- The kinase LYK5 is a MAjor chitin receptor in Arabidopsis and forms a chitin-induced complex with related kinase CERK1.
Cao Y, Liang Y, Tanaka K, Nguyen CT, Jedrzejczak RP, Joachimiak A, Stacey G
MCSG, eLife
(Details)(Pubmed ID: 25340959)
Times cited: 113
- Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.
LohMAn DC, Forouhar F, Beebe ET, Stefely MS, Minogue CE, Ulbrich A, Stefely JA, SukuMAr S, Luna-Sánchez M, Jochem A, Lew S, SeetharaMAn J, Xiao R, Wang H, Westphall MS, Wrobel RL, Everett JK, Mitchell JC, López LC, Coon JJ, Tong L, Pagliarini DJ
MPP+NESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 25339443)
PDB ID(s): 4RHP
Times cited: 46
- Structural characterization of the putative ABC-type 2 transporter from Thermotoga MAritiMA MSB8.
Filippova EV, Tkaczuk KL, Chruszcz M, Xu X, Savchenko A, Edwards A, Minor W
MCSG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 25306867)
PDB ID(s): 3CNI
Times cited: 0
- Structural analysis of arabinose-5-phosphate isomerase from Bacteroides fragilis and functional implications.
Chiu HJ, Grant JC, Farr CL, Jaroszewski L, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 25286848)
PDB ID(s): 3ETN
Times cited: 0
- Structural and functional divergence of the aldolase fold in ToxoplasMA gondii
Tonkin, M.L., Halavaty, A.S., RaMAswamy, R., Ruan, J., Igarashi, M., Ngô, H.M. and Boulanger, M.J.
CSGID, Journal of Molecular Biology
(Details)(Pubmed ID: 25284756)
Times cited: 6
- Solution structure of a C-terminal fragment (175-257) of CV_0373 protein from Chromobacterium violaceum adopts a winged helix-turn-helix (wHTH) fold.
Yang Y, Ramelot TA, Lee HW, Xiao R, Everett JK, Montelione GT, Prestegard JH, Kennedy MA
NESG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 25270885)
Times cited: 0
- A Gly-zipper motif mediates homodimerization of the transmembrane doMAin of the mitochondrial kinase ADCK3.
Khadria AS, Mueller BK, Stefely JA, Tan CH, Pagliarini DJ, Senes A
MPP, Journal of the American Chemical Society
(Details)(Pubmed ID: 25216398)
Times cited: 9
- The CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis contains a [2Fe-2S] cluster: crystal structure and nuclease activity.
LeMAk S, Nocek B, Beloglazova N, Skarina T, Flick R, Brown G, Joachimiak A, Savchenko A, Yakunin AF
MCSG, Nucleic Acids Research
(Details)(Pubmed ID: 25200083)
PDB ID(s): 4R5Q
Times cited: 14
- Structural Insights into the Recognition of Phosphopeptide by the FHA DoMAin of Kanadaptin.
Xu Q, Deller MC, Nielsen TK, Grant JC, Lesley SA, Elsliger MA, Deacon AM, Wilson IA
JCSG, PLoS ONE
(Details)(Pubmed ID: 25197798)
PDB ID(s): 4H87
Times cited: 2
- Solution structure of the free Zα doMAin of huMAn DLM-1 (ZBP1/DAI), a Z-DNA binding doMAin.
Yang Y, Ramelot TA, Lee HW, Xiao R, Everett JK, Montelione GT, Prestegard JH, Kennedy MA
NESG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 25173411)
Times cited: 1
- Structure of RNA 3'-phosphate cyclase bound to substrate RNA.
Desai KK, BingMAn CA, Cheng CL, Phillips GN, Raines RT
NATPRO+NatPro, RNA (New York, N.Y.)
(Details)(Pubmed ID: 25161314)
Times cited: 1
- Characterizing RNA ensembles from NMR data with kineMAtic models.
Fonseca R, Pachov DV, Bernauer J, van den Bedem H
JCSG, Nucleic Acids Research
(Details)(Pubmed ID: 25114056)
Times cited: 16
- Radiation DaMAge of Myoglobin Crystals in Weak Stationary Electric and MAgnetic Fields.
Trame CB, Dragovic M, Chiu HJ
JCSG, Journal of physics. Conference series
(Details)(Pubmed ID: 25089148)
Times cited: 0
- Nucleotide-dependent interactions within a specialized Hsp70/Hsp40 complex involved in Fe-S cluster biogenesis.
Kim JH, Alderson TR, Frederick RO, MArkley JL
MPP, Journal of the American Chemical Society
(Details)(Pubmed ID: 25080945)
Times cited: 13
- Structure-guided functional characterization of enediyne self-sacrifice resistance proteins CalU16 and CalU19.
Elshahawi SI, Ramelot TA, SeetharaMAn J, Chen J, Singh S, Yang Y, Pederson K, Kharel MK, Xiao R, Lew S, YennaMAlli RM, Miller MD, Wang F, Tong L, Montelione GT, Kennedy MA, BingMAn CA, Zhu H, Phillips GN, Thorson JS
NatPro+NESG, ACS Chemical Biology
(Details)(Pubmed ID: 25079510)
Times cited: 9
- pH-induced conforMAtional change of IscU at low pH correlates with protonation/deprotonation of two conserved histidine residues.
Dai Z, Kim JH, Tonelli M, Ali IK, MArkley JL
MPP, Biochemistry
(Details)(Pubmed ID: 25055301)
Times cited: 5
- The crystal structure of BlmI as a model for nonribosoMAl peptide synthetase peptidyl carrier proteins.
LohMAn JR, MA M, Cuff ME, Bigelow L, Bearden J, Babnigg G, Joachimiak A, Phillips GN, Shen B
MCSG+NatPro, Proteins
(Details)(Pubmed ID: 25050442)
PDB ID(s): 4NEO
Times cited: 18
- Crystal structures of three representatives of a new Pfam family PF14869 (DUF4488) suggest they function in sugar binding/uptake.
KuMAr A, Punta M, Axelrod HL, Das D, Farr CL, Grant JC, Chiu HJ, Miller MD, Coggill PC, Klock HE, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Protein Science
(Details)(Pubmed ID: 25044324)
PDB ID(s): 4GZV 4IAB 4I95
Times cited: 1
- Double trouble-Buffer selection and His-tag presence MAy be responsible for nonreproducibility of biomedical experiments.
MAjorek KA, Kuhn ML, Chruszcz M, Anderson WF, Minor W
CSGID+MCSG, Protein Science
(Details)(Pubmed ID: 25044180)
Times cited: 28
- Molecular imprinting as a signal-activation mechanism of the viral RNA sensor RIG-I.
Wu B, Peisley A, Tetrault D, Li Z, EgelMAn EH, MAgor KE, Walz T, Penczek PA, Hur S
TEMIMPS, Molecular Cell
(Details)(Pubmed ID: 25018021)
PDB ID(s): 3J6J 4P4H
Times cited: 89
- Salvage of the thiamin pyrimidine moiety by plant TenA proteins lacking an active-site cysteine.
Zallot R, Yazdani M, Goyer A, ZieMAk MJ, Guan JC, McCarty DR, de Crecy-Lagard V, Gerdes S, Garrett TJ, Benach J, Hunt JF, Shintani DK, Hanson AD
NESG, Biochemical Journal
(Details)(Pubmed ID: 25014715)
Times cited: 11
- Structural and Functional Characterization of DUF1471 DoMAins of Salmonella Proteins SrfN, YdgH/SssB, and YahO.
Eletsky A, Michalska K, Houliston S, Zhang Q, Daily MD, Xu X, Cui H, Yee A, LeMAk A, Wu B, Garcia M, Burnet MC, Meyer KM, Aryal UK, Sanchez O, Ansong C, Xiao R, Acton TB, Adkins JN, Montelione GT, Joachimiak A, Arrowsmith CH, Savchenko A, Szyperski T, Cort JR
MCSG+NESG+PCSEP, PLoS ONE
(Details)(Pubmed ID: 25010333)
PDB ID(s): 4EVU
Times cited: 4
- Structure of the RNA polymerase assembly factor Crl and identification of its interaction surface with sigMA S.
Banta AB, Cuff ME, Lin H, Myers AR, Ross W, Joachimiak A, Gourse RL
MCSG, Journal of Bacteriology
(Details)(Pubmed ID: 25002538)
PDB ID(s): 3RPJ
Times cited: 6
- Solution NMR structures of immunoglobulin-like doMAins 7 and 12 from obscurin-like protein 1 contribute to the structural coverage of the huMAn cancer protein interaction network.
Pulavarti SV, Huang YJ, Pederson K, Acton TB, Xiao R, Everett JK, Prestegard JH, Montelione GT, Szyperski T
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 24989974)
Times cited: 0
- HuMAn-chroMAtin-related protein interactions identify a demethylase complex required for chromosome segregation.
MArcon E, Ni Z, Pu S, Turinsky AL, Trimble SS, Olsen JB, SilverMAn-Gavrila R, SilverMAn-Gavrila L, Phanse S, Guo H, Zhong G, Guo X, Young P, Bailey S, Roudeva D, Zhao D, Hewel J, Li J, Gräslund S, Paduch M, Kossiakoff AA, Lupien M, Emili A, Wodak SJ, Greenblatt J
CEBS, Cell reports
(Details)(Pubmed ID: 24981860)
Times cited: 26
- Comparing chemistry to outcome: the development of a chemical distance metric, coupled with clustering and hierarchal visualization applied to MAcromolecular crystallography.
Bruno AE, Ruby AM, Luft JR, Grant TD, SeetharaMAn J, Montelione GT, Hunt JF, Snell EH
NESG, PLoS ONE
(Details)(Pubmed ID: 24971458)
Times cited: 9
- Solution NMR structures of homeodoMAins from huMAn proteins ALX4, ZHX1, and CASP8AP2 contribute to the structural coverage of the HuMAn Cancer Protein Interaction Network.
Xu X, Pulavarti SV, Eletsky A, Huang YJ, Acton TB, Xiao R, Everett JK, Montelione GT, Szyperski T
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 24941917)
Times cited: 1
- Structure- and context-based analysis of the GxGYxYP family reveals a new putative class of Glycoside Hydrolase.
Rigden DJ, Eberhardt RY, Gilbert HJ, Xu Q, Chang Y, Godzik A
JCSG, BMC Bioinformatics
(Details)(Pubmed ID: 24938123)
PDB ID(s): 3SGG
Times cited: 6
- Solution Structure of the 2A Protease from a Common Cold Agent, HuMAn Rhinovirus C2, Strain W12.
Lee W, Watters KE, Troupis AT, Reinen NM, Suchy FP, Moyer KL, Frederick RO, Tonelli M, Aceti DJ, Palmenberg AC, MArkley JL
MPP, PLoS ONE
(Details)(Pubmed ID: 24937088)
PDB ID(s): 2M5T
Times cited: 5
- Plant, AniMAl, and Fungal Micronutrient Queuosine Is Salvaged by Members of the DUF2419 Protein Family.
Zallot R, Brochier-ArMAnet C, Gaston KW, Forouhar F, Limbach PA, Hunt JF, de Crécy-Lagard V
NESG, ACS Chemical Biology
(Details)(Pubmed ID: 24911101)
Times cited: 13
- Using a commodity high-definition television for collaborative structural biology.
YennaMAlli R, Arangarasan R, Bryden A, Gleicher M, Phillips GN
NATPRO+NatPro, Journal of Applied Crystallography
(Details)(Pubmed ID: 24904249)
Times cited: 6
- Structural basis for a pH-sensitive calcium leak across membranes.
Chang Y, Bruni R, Kloss B, Assur Z, KloppMAnn E, Rost B, Hendrickson WA, Liu Q
NYCOMPS, Science
(Details)(Pubmed ID: 24904158)
PDB ID(s): 4PGW 4PGV 4PGU 4PGS 4PGR
Times cited: 33
- Structural bioinforMAtics of the interactome.
Petrey D, Honig B
NESG, Annual review of biophysics
(Details)(Pubmed ID: 24895853)
Times cited: 28
- Molecular characterization of novel pyridoxal-5'-phosphate-dependent enzymes from the huMAn microbiome.
FleischMAn NM, Das D, KuMAr A, Xu Q, Chiu HJ, Jaroszewski L, Knuth MW, Klock HE, Miller MD, Elsliger MA, Godzik A, Lesley SA, Deacon AM, Wilson IA, Toney MD
JCSG, Protein Science
(Details)(Pubmed ID: 24888348)
PDB ID(s): 3ELE 3F0H 3G0T
Times cited: 4
- Crystal Cryocooling Distorts ConforMAtional Heterogeneity in a Model Michaelis Complex of DHFR.
Keedy DA, van den Bedem H, Sivak DA, Petsko GA, Ringe D, Wilson MA, Fraser JS
JCSG, Structure
(Details)(Pubmed ID: 24882744)
Times cited: 39
- The oligomeric states of the purified sigMA-1 receptor are stabilized by ligands.
Gromek KA, Suchy FP, Meddaugh HR, Wrobel RL, LaPointe LM, Chu UB, Primm JG, Ruoho AE, Senes A, Fox BG
TMPC, Journal of Biological Chemistry
(Details)(Pubmed ID: 24847081)
Times cited: 35
- Role of IscX in Iron-Sulfur Cluster Biogenesis in Escherichia coli.
Kim JH, Bothe JR, Frederick RO, Holder JC, MArkley JL
MPP, Journal of the American Chemical Society
(Details)(Pubmed ID: 24810328)
Times cited: 27
- The dimerization doMAin in DapE enzymes is required for catalysis.
Nocek B, Starus A, MAkowska-Grzyska M, Gutierrez B, Sanchez S, Jedrzejczak R, MAck JC, Olsen KW, Joachimiak A, Holz RC
CSGID+MCSG, PLoS ONE
(Details)(Pubmed ID: 24806882)
PDB ID(s): 4OP4
Times cited: 6
- Agonist-bound structure of the huMAn P2Y12 receptor.
Zhang J, Zhang K, Gao ZG, Paoletta S, Zhang D, Han GW, Li T, MA L, Zhang W, Müller CE, Yang H, Jiang H, Cherezov V, Katritch V, Jacobson KA, Stevens RC, Wu B, Zhao Q
GPCR, Nature
(Details)(Pubmed ID: 24784220)
PDB ID(s): 4PY0 4PXZ
Times cited: 135
- Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.
Kuhn ML, ZeMAitaitis B, Hu LI, Sahu A, Sorensen D, Minasov G, LiMA BP, Scholle M, Mrksich M, Anderson WF, Gibson BW, Schilling B, Wolfe AJ
CSGID, PLoS ONE
(Details)(Pubmed ID: 24756028)
PDB ID(s): 4K6A 4MVA 4MVJ
Times cited: 120
- Potent dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement.
Edeling MA, Austin SK, Shrestha B, Dowd KA, Mukherjee S, Nelson CA, Johnson S, MAbila MN, Christian EA, Rucker J, Pierson TC, Diamond MS, Fremont DH
CSGID, PLos Pathogens
(Details)(Pubmed ID: 24743696)
Times cited: 20
- Structural genomics analysis of uncharacterized protein families overrepresented in huMAn gut bacteria identifies a novel glycoside hydrolase.
Sheydina A, Eberhardt RY, Rigden DJ, Chang Y, Li Z, ZMAsek CC, Axelrod HL, Godzik A
JCSG, BMC Bioinformatics
(Details)(Pubmed ID: 24742328)
PDB ID(s): 3KZS
Times cited: 6
- Polypeptide backbone, C(β) and methyl group resonance assignments of the 24 kDa plectin repeat doMAin 6 from huMAn protein plectin.
Pulavarti SV, Eletsky A, Huang YJ, Acton TB, Xiao R, Everett JK, Montelione GT, Szyperski T
NESG, Biomolecular NMR Assignments
(Details)(Pubmed ID: 24722902)
Times cited: 0
- Better and faster: improvements and optimization for MAmMAlian recombinant protein production.
Almo SC, Love JD
NYSGRC, Current Opinion in Structural Biology
(Details)(Pubmed ID: 24721463)
Times cited: 26
- Type III Effector NleH2 from Escherichia coli O157:H7 str. Sakai Features an Atypical Protein Kinase DoMAin
Halavaty AS, Anderson SM, Wawrzak Z, Kudritska M, Skarina T, Anderson WF, Savchenko A.
CSGID, Biochemistry
(Details)(Pubmed ID: 24712300)
PDB ID(s): 4O96
Times cited: 5
- Design of activated serine-containing catalytic triads with atomic-level accuracy.
Rajagopalan S, Wang C, Yu K, Kuzin AP, Richter F, Lew S, Miklos AE, MAtthews ML, SeetharaMAn J, Su M, Hunt JF, Cravatt BF, Baker D
NESG, Nature Chemical Biology
(Details)(Pubmed ID: 24705591)
Times cited: 31
- AutoMAted identification of elemental ions in MAcromolecular crystal structures.
Echols N, Morshed N, Afonine PV, McCoy AJ, Miller MD, Read RJ, Richardson JS, Terwilliger TC, Adams PD
JCSG, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 24699654)
Times cited: 15
- Differential scales of protein quality control.
Wolff S, WeissMAn JS, Dillin A
HOMEO, Cell
(Details)(Pubmed ID: 24679526)
Times cited: 115
- Structure of the huMAn P2Y12 receptor in complex with an antithrombotic drug.
Zhang K, Zhang J, Gao ZG, Zhang D, Zhu L, Han GW, Moss SM, Paoletta S, Kiselev E, Lu W, Fenalti G, Zhang W, Müller CE, Yang H, Jiang H, Cherezov V, Katritch V, Jacobson KA, Stevens RC, Wu B, Zhao Q
GPCR, Nature
(Details)(Pubmed ID: 24670650)
PDB ID(s): 4NTJ
Times cited: 161
- Basic Tilted Helix Bundle - A new protein fold in huMAn FKBP25/FKBP3 and HectD1.
Helander S, Montecchio M, LeMAk A, Farès C, Almlöf J, Li Y, Yee A, Arrowsmith CH, Dhe-Paganon S, Sunnerhagen M
NESG, Biochemical and biophysical research communications
(Details)(Pubmed ID: 24667607)
Times cited: 10
- Sparse labeling of proteins: structural characterization from long range constraints.
Prestegard JH, Agard DA, Moremen KW, Lavery LA, Morris LC, Pederson K
NESG, Journal of magnetic resonance (San Diego, Calif. : 1997)
(Details)(Pubmed ID: 24656078)
Times cited: 9
- Membrane protein stability can be compromised by detergent interactions with the extramembranous soluble doMAins.
Yang Z, Wang C, Zhou Q, An J, Hildebrandt E, Aleksandrov LA, Kappes JC, DeLucas LJ, Riordan JR, Urbatsch IL, Hunt JF, Brouillette CG
NESG, Protein Science
(Details)(Pubmed ID: 24652590)
Times cited: 35
- Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus.
Wang F, Singh S, Zhang J, Huber TD, Helmich KE, Sunkara M, Hurley KA, Goff RD, BingMAn CA, Morris AJ, Thorson JS, Phillips GN
NATPRO+NatPro, FEBS Journal
(Details)(Pubmed ID: 24649856)
PDB ID(s): 4HPV 4K0B 4L7I 4LZ2
Times cited: 11
- Structure and computational analysis of a novel protein with metallopeptidase-like and circularly permuted winged-helix-turn-helix doMAins reveals a possible role in modified polysaccharide biosynthesis.
Das D, Murzin AG, Rawlings ND, Finn RD, Coggill P, BateMAn A, Godzik A, Aravind L
JCSG, BMC Bioinformatics
(Details)(Pubmed ID: 24646163)
PDB ID(s): 3K9T
Times cited: 1
- Approaches to autoMAted protein crystal harvesting.
Deller MC, Rupp B
JCSG, Acta crystallographica. Section F, Structural biology communications
(Details)(Pubmed ID: 24637746)
Times cited: 19
- Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction.
Aiyer S, Swapna GV, MAlani N, Aramini JM, Schneider WM, Plumb MR, Ghanem M, Larue RC, SharMA A, Studamire B, Kvaratskhelia M, BushMAn FD, Montelione GT, Roth MJ
NESG, Nucleic Acids Research
(Details)(Pubmed ID: 24623816)
Times cited: 30
- Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic doMAin relative to a bilayer.
Monk BC, ToMAsiak TM, Keniya MV, HuschMAnn FU, Tyndall JD, O'Connell JD, Cannon RD, McDonald JG, Rodriguez A, Finer-Moore JS, Stroud RM
CSMP, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 24613931)
PDB ID(s): 4LXJ 4K0F
Times cited: 114
- Purification and structural study of the voltage-sensor doMAin of the huMAn KCNQ1 potassium ion channel.
Peng D, Kim JH, Kroncke BM, Law CL, Xia Y, Droege KD, Van Horn WD, Vanoye CG, Sanders CR
MPSbyNMR, Biochemistry
(Details)(Pubmed ID: 24606221)
PDB ID(s): 2R9R 1ORS 2A0L 1ORQ 2KYH 4DXW 3RYV 3BEH
Times cited: 15
- Structure of a class C GPCR metabotropic glutaMAte receptor 1 bound to an allosteric modulator.
Wu H, Wang C, Gregory KJ, Han GW, Cho HP, Xia Y, Niswender CM, Katritch V, Meiler J, Cherezov V, Conn PJ, Stevens RC
GPCR, Science
(Details)(Pubmed ID: 24603153)
PDB ID(s): 4OR2
Times cited: 261
- Structural basis of Flavivirus NS1 assembly and antibody recognition.
Edeling MA, Diamond MS, Fremont DH
CSGID, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 24594604)
Times cited: 50
- Purification and biophysical characterization of the CapA membrane protein FTT0807 from Francisella tularensis.
MArtin-Garcia JM, Hansen DT, Zook J, Loskutov AV, Robida MD, Craciunescu FM, Sykes KF, Wachter RM, Fromme P, Allen JP
MPID, Biochemistry
(Details)(Pubmed ID: 24593131)
Times cited: 6
- Ligand screening using fluorescence therMAl shift analysis (FTS).
Luan CH, Light SH, Dunne SF, Anderson WF
CSGID, Methods in Molecular Biology
(Details)(Pubmed ID: 24590724)
Times cited: 3
- Salvage of failed protein targets by reductive alkylation.
Tan K, Kim Y, Hatzos-Skintges C, Chang C, Cuff M, Chhor G, Osipiuk J, Michalska K, Nocek B, An H, Babnigg G, Bigelow L, Joachimiak G, Li H, MAck J, MAkowska-Grzyska M, MAltseva N, Mulligan R, Tesar C, Zhou M, Joachimiak A
CSGID+MCSG, Methods in Molecular Biology
(Details)(Pubmed ID: 24590719)
Times cited: 2
- AutoMAted cell-free protein production methods for structural studies.
Beebe ET, MAkino S, MArkley JL, Fox BG
MPP+TMPC, Methods in Molecular Biology
(Details)(Pubmed ID: 24590713)
Times cited: 2
- Protein Production for Structural Genomics Using E. coli Expression.
MAkowska-Grzyska M, Kim Y, MAltseva N, Li H, Zhou M, Joachimiak G, Babnigg G, Joachimiak A
CSGID+MCSG, Methods in Molecular Biology
(Details)(Pubmed ID: 24590711)
Times cited: 8
- Structural genomics of huMAn proteins.
OsMAn KT, Edwards A
CSGID, Methods in Molecular Biology
(Details)(Pubmed ID: 24590706)
Times cited: 1
- Data MAnagement in the modern structural biology and biomedical research environment.
ZimmerMAn MD, Grabowski M, DoMAgalski MJ, MAclean EM, Chruszcz M, Minor W
CSGID+MCSG+NYSGRC, Methods in Molecular Biology
(Details)(Pubmed ID: 24590705)
Times cited: 14
- (19)F NMR reveals multiple conforMAtions at the dimer interface of the nonstructural protein 1 effector doMAin from influenza A virus.
Aramini JM, Hamilton K, MA LC, Swapna GV, Leonard PG, Ladbury JE, Krug RM, Montelione GT
NESG, Structure
(Details)(Pubmed ID: 24582435)
Times cited: 18
- Sensor doMAin of histidine kinase KinB of Pseudomonas - a helix-swapped dimer.
Tan K, Chhor G, Binkowski TA, Jedrzejczak RP, MAkowska-Grzyska M, Joachimiak A
MCSG, Journal of Biological Chemistry
(Details)(Pubmed ID: 24573685)
PDB ID(s): 3KKB 3L34 4LLE 4LLC
Times cited: 5
- An RNA aptamer possessing a novel monovalent cation-mediated fold inhibits lysozyme catalysis by inhibiting the binding of long natural substrates.
Padlan CS, MAlashkevich VN, Almo SC, Levy M, Brenowitz M, Girvin ME
IFN+NYSGRC, RNA (New York, N.Y.)
(Details)(Pubmed ID: 24570482)
PDB ID(s): 4M4O 4M6D
Times cited: 14
- Trends in structural coverage of the protein universe and the impact of the Protein Structure Initiative.
Khafizov K, MAdrid-Aliste C, Almo SC, Fiser A
NYSGRC, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 24567391)
Times cited: 41
- Adherence to Bürgi-Dunitz stereochemical principles requires significant structural rearrangements in Schiff-base forMAtion: insights from transaldolase complexes.
Light SH, Minasov G, Duban ME, Anderson WF
CSGID, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 24531488)
PDB ID(s): 4E0C 3TE9 3TK7 3TKF 3TNO
Times cited: 9
- X-ray crystal structure of the passenger doMAin of plasmid encoded toxin(Pet), an autotransporter enterotoxin from enteroaggregative Escherichia coli (EAEC).
Domingo Meza-Aguilar J, Fromme P, Torres-Larios A, Mendoza-Hernández G, Hernandez-Chiñas U, Arreguin-Espinosa de Los Monteros RA, Eslava Campos CA, Fromme R
MPID, Biochemical and biophysical research communications
(Details)(Pubmed ID: 24530907)
PDB ID(s): 4OM9
Times cited: 7
- Structure and Function of HuMAn DnaJ Homologue Subfamily A Member 1 (DNAJA1) and Its Relationship to Pancreatic Cancer.
Stark JL, Mehla K, Chaika N, Acton TB, Xiao R, Singh PK, Montelione GT, Powers R
NESG, Biochemistry
(Details)(Pubmed ID: 24512202)
Times cited: 20
- Isolation of single-base genome-edited huMAn iPS cells without antibiotic selection.
Miyaoka Y, Chan AH, Judge LM, Yoo J, Huang M, Nguyen TD, Lizarraga PP, So PL, Conklin BR
STEMCELL, Nature Methods
(Details)(Pubmed ID: 24509632)
Times cited: 82
- Principal components analysis of protein sequence clusters.
Wang B, Kennedy MA
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 24496727)
Times cited: 2
- In Silico Derived SMAll Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity.
Brown CS, Lee MS, Leung DW, Wang T, Xu W, Luthra P, AnantpadMA M, ShabMAn RS, Melito LM, MAcmillan KS, Borek DM, Otwinowski Z, RaMAnan P, Stubbs AJ, Peterson DS, Binning JM, Tonelli M, Olson MA, Davey RA, Ready JM, Basler CF, AMArasinghe GK
CSGID, Journal of Molecular Biology
(Details)(Pubmed ID: 24495995)
PDB ID(s): 4IBB 4IBE 4IBF
Times cited: 32
- Structural mechanism of voltage-dependent gating in an isolated voltage-sensing doMAin.
Li Q, Wanderling S, Paduch M, Medovoy D, Singharoy A, McGreevy R, Villalba-Galea CA, Hulse RE, Roux B, Schulten K, Kossiakoff A, Perozo E
CEBS, Nature Structural & Molecular Biology
(Details)(Pubmed ID: 24487958)
PDB ID(s): 4G7V 4G7Y 4G80
Times cited: 111
- Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism.
Lavery LA, Partridge JR, Ramelot TA, Elnatan D, Kennedy MA, Agard DA
NESG, Molecular Cell
(Details)(Pubmed ID: 24462206)
Times cited: 55
- Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila
Srinivasan B, Forouhar F, Shukla A, Sampangi C, Kulkarni S, Abashidze M, SeetharaMAn J, Lew S, MAo L, Acton TB, Xiao R, Everett JK, Montelione GT, Tong L, Balaram H
NESG, FEBS Journal
(Details)(Pubmed ID: 24456211)
Times cited: 5
- Structure of the DNA-Binding and RNA-Polymerase-Binding Region of Transcription Antitermination Factor λQ
Vorobiev SM, Gensler Y, Vahedian-Movahed H, SeetharaMAn J, Su M, Huang JY, Xiao R, Kornhaber G, Montelione GT, Tong L, Ebright RH, Nickels BE
NESG, Structure
(Details)(Pubmed ID: 24440517)
Times cited: 4
- Structure of cyclin G-associated kinase (GAK) trapped in different conforMAtions using nanobodies.
Chaikuad A, Keates T, Vincke C, Kaufholz M, Zenn M, ZimmerMAnn B, Gutiérrez C, Zhang RG, Hatzos-Skintges C, Joachimiak A, MuylderMAns S, Herberg FW, Knapp S, Müller S
MCSG, Biochemical Journal
(Details)(Pubmed ID: 24438162)
PDB ID(s): 4O38
Times cited: 19
- Crystal Structures of Type I Dehydroquinate Dehydratase in Complex with Quinate and ShikiMAte Suggest a Novel Mechanism of Schiff Base ForMAtion.
Light SH, Antanasijevic A, Krishna SN, Caffrey MS, Anderson WF, Lavie A
CSGID, Biochemistry
(Details)(Pubmed ID: 24437575)
PDB ID(s): 4GUI 4GUJ 4IUO
Times cited: 7
- A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation.
Desai KK, Cheng CL, BingMAn CA, Phillips GN, Raines RT
NatPro, Nucleic Acids Research
(Details)(Pubmed ID: 24435797)
PDB ID(s): 4N2P
Times cited: 18
- Cell-free translation of biofuel enzymes.
Takasuka TE, Walker JA, BergeMAn LF, Meulen KA, MAkino S, Elsen NL, Fox BG
TMPC, Methods in Molecular Biology
(Details)(Pubmed ID: 24395410)
Times cited: 9
- Protein NMR Structures Refined with Rosetta Have Higher Accuracy Relative to Corresponding X-ray Crystal Structures.
MAo B, Tejero R, Baker D, Montelione GT
NESG, Journal of the American Chemical Society
(Details)(Pubmed ID: 24392845)
Times cited: 30
- EttA regulates translation by binding the ribosoMAl E site and restricting ribosome-tRNA dynamics.
Chen B, Boël G, Hashem Y, Ning W, Fei J, Wang C, Gonzalez RL, Hunt JF, Frank J
NESG, Nature Structural & Molecular Biology
(Details)(Pubmed ID: 24389465)
Times cited: 26
- New mini- zincin structures provide a miniMAl scaffold for members of this metallopeptidase superfamily.
Trame CB, Chang Y, Axelrod HL, Eberhardt RY, Coggill P, Punta M, Rawlings ND
JCSG, BMC Bioinformatics
(Details)(Pubmed ID: 24383880)
PDB ID(s): 3E11
Times cited: 0
- The future of crystallography in drug discovery.
Zheng H, Hou J, ZimmerMAn MD, Wlodawer A, Minor W
CSGID+MCSG+NYSGRC, Expert Opin Drug Discov
(Details)(Pubmed ID: 24372145)
Times cited: 20
- Insights into the structure of class B GPCRs.
Hollenstein K, de Graaf C, Bortolato A, Wang MW, MArshall FH, Stevens RC
GPCR, Trends in pharmacological sciences
(Details)(Pubmed ID: 24359917)
Times cited: 99
- Validation of metal-binding sites in MAcromolecular structures with the CheckMyMetal web server.
Zheng H, Chordia MD, Cooper DR, Chruszcz M, Müller P, Sheldrick GM, Minor W
CSGID, Nature Protocols
(Details)(Pubmed ID: 24356774)
Times cited: 131
- Structural characterization of the glycoprotein GP2 core doMAin from the CAS virus, a novel arenavirus-like species.
Koellhoffer JF, Dai Z, MAlashkevich VN, Stenglein MD, Liu Y, Toro R, S Harrison J, Chandran K, DeRisi JL, Almo SC, Lai JR
NYSGRC, Journal of Molecular Biology
(Details)(Pubmed ID: 24333483)
PDB ID(s): 4N23 4N21
Times cited: 13
- Assessment of template-based protein structure predictions in CASP10.
Huang YJ, MAo B, Aramini JM, Montelione GT
NESG, Proteins
(Details)(Pubmed ID: 24323734)
Times cited: 59
- Structural basis of the alternating-access mechanism in a bile acid transporter.
Zhou X, Levin EJ, Pan Y, McCoy JG, SharMA R, Kloss B, Bruni R, Quick M, Zhou M
NYCOMPS, Nature
(Details)(Pubmed ID: 24317697)
PDB ID(s): 4N7X 4N7W
Times cited: 53
- ModBase, a database of annotated comparative protein structure models and associated resources.
Pieper U, Webb BM, Dong GQ, SchneidMAn-Duhovny D, Fan H, Kim SJ, Khuri N, Spill YG, Weinkam P, Hammel M, Tainer JA, Nilges M, Sali A
CSMP+NYSGRC, Nucleic Acids Research
(Details)(Pubmed ID: 24271400)
Times cited: 90
- Functional clustering of immunoglobulin superfamily proteins with protein-protein interaction inforMAtion calibrated hidden MArkov model sequence profiles.
Yap EH, Rosche T, Almo S, Fiser A
NYSGRC, Journal of Molecular Biology
(Details)(Pubmed ID: 24246499)
Times cited: 10
- DNASU plasmid and PSI:Biology-MAterials repositories: resources to accelerate biological research.
Seiler CY, Park JG, SharMA A, Hunter P, Surapaneni P, Sedillo C, Field J, Algar R, Price A, Steel J, Throop A, Fiacco M, LaBaer J
PSIMR, Nucleic Acids Research
(Details)(Pubmed ID: 24225319)
Times cited: 75
- The transporter classification database.
Saier MH, Reddy VS, TaMAng DG, VästerMArk A
TransportPDB, Nucleic Acids Research
(Details)(Pubmed ID: 24225317)
Times cited: 191
- The second extracellular loop of the adenosine A1 receptor mediates activity of allosteric enhancers.
Kennedy DP, McRobb FM, Leonhardt SA, Purdy M, Figler H, MArshall MA, Chordia M, Figler R, Linden J, Abagyan R, Yeager M
CHSAM+GPCR, Molecular pharmacology
(Details)(Pubmed ID: 24217444)
Times cited: 13
- The quality and validation of structures from structural genomics.
DoMAgalski MJ, Zheng H, ZimmerMAn MD, Dauter Z, Wlodawer A, Minor W
CSGID+MCSG+NYSGRC, Methods in Molecular Biology
(Details)(Pubmed ID: 24203341)
Times cited: 9
- Applications of NMR-based PRE and EPR-based DEER spectroscopy to homodimer chain exchange characterization and structure determination.
Yang Y, Ramelot TA, Ni S, McCarrick RM, Kennedy MA
NESG, Methods in Molecular Biology
(Details)(Pubmed ID: 24203336)
Times cited: 0
- Cell-free protein synthesis for functional and structural studies.
MAkino S, Beebe ET, MArkley JL, Fox BG
MPP+TMPC, Methods in Molecular Biology
(Details)(Pubmed ID: 24203331)
Times cited: 8
- Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family.
Das D, Chiu HJ, Farr CL, Grant JC, Jaroszewski L, Knuth MW, Miller MD, Tien HJ, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 24174223)
PDB ID(s): 3NPD
Times cited: 2
- Targeting DXP synthase in huMAn pathogens: enzyme inhibition and antimicrobial activity of butylacetylphosphonate.
Smith JM, Warrington NV, Vierling RJ, Kuhn ML, Anderson WF, Koppisch AT, Freel Meyers CL
CSGID, The Journal of antibiotics
(Details)(Pubmed ID: 24169798)
Times cited: 21
- Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design.
Bjelic S, Kipnis Y, Wang L, Pianowski Z, Vorobiev S, Su M, SeetharaMAn J, Xiao R, Kornhaber G, Hunt JF, Tong L, Hilvert D, Baker D
NESG, Journal of Molecular Biology
(Details)(Pubmed ID: 24161950)
Times cited: 19
- Structure of a prokaryotic sodium channel pore reveals essential gating elements and an outer ion binding site common to eukaryotic channels.
Shaya D, Findeisen F, AbdereMAne-Ali F, Arrigoni C, Wong S, Nurva SR, Loussouarn G, Minor DL
CSMP, Journal of Molecular Biology
(Details)(Pubmed ID: 24120938)
PDB ID(s): 4LTR 4LTQ 4LTP 4LTO
Times cited: 72
- Disruption of helix-capping residues 671 and 674 reveals a role in HIV-1 entry for a specialized hinge segment of the membrane proxiMAl external region of gp41.
Sun ZY, Cheng Y, Kim M, Song L, Choi J, Kudahl UJ, Brusic V, Chowdhury B, Yu L, SeaMAn MS, Bellot G, Shih WM, Wagner G, Reinherz EL
MPSbyNMR, Journal of Molecular Biology
(Details)(Pubmed ID: 24075869)
PDB ID(s): 2ME1 2ME2 2ME3 2ME4
Times cited: 24
- Fluorescent approaches for understanding interactions of ligands with G protein coupled receptors.
Sridharan R, Zuber J, Connelly SM, MAthew E, Dumont ME
MPSBC, Biochimica et biophysica acta
(Details)(Pubmed ID: 24055822)
Times cited: 46
- The miniMAlist architectures of viroporins and their therapeutic implications.
OuYang B, Chou JJ
MPSbyNMR, Biochimica et biophysica acta
(Details)(Pubmed ID: 24055819)
PDB ID(s): 2KIX 2RLF 3LBW
Times cited: 23
- Structures of a bifunctional cell wall hydrolase CwlT containing a novel bacterial lysozyme and an NlpC/P60 DL-endopeptidase.
Xu Q, Chiu HJ, Farr CL, Jaroszewski L, Knuth MW, Miller MD, Lesley SA, Godzik A, Elsliger MA, Deacon AM, Wilson IA
JCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 24051416)
PDB ID(s): 4FDY 4HPE
Times cited: 11
- The HuMAn Proteome Organization Chromosome 6 Consortium: Integrating chromosome-centric and biology/disease driven strategies.
Borchers CH, Kast J, Foster LJ, Siu KW, Overall CM, Binkowski TA, Hildebrand WH, Scherer A, MAnsoor M, Keown PA
MCSG, Journal of proteomics
(Details)(Pubmed ID: 23933161)
Times cited: 5
- Crystal structure of a member of a novel family of dioxygenases (PF10014) reveals a conserved cupin fold and active site.
Xu Q, Grant J, Chiu HJ, Farr CL, Jaroszewski L, Knuth MW, Miller MD, Lesley SA, Godzik A, Elsliger MA, Deacon AM, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 23852666)
PDB ID(s): 3PL0
Times cited: 2
- Structural and functional characterization of BaiA, an enzyme involved in secondary bile acid synthesis in huMAn gut microbe.
Bhowmik S, Jones DH, Chiu HP, Park IH, Chiu HJ, Axelrod HL, Farr CL, Tien HJ, Agarwalla S, Lesley SA
JCSG, Proteins
(Details)(Pubmed ID: 23836456)
PDB ID(s): 4IS2 4IS3
Times cited: 8
- Crystallisation of proteins and MAcromolecular complexes: Past, present and future
Deller, MC, Rupp B
JCSG, eLS
(Details)
Times cited: 0
2013
- Biophysical characterization of α-synuclein and its controversial structure.
Alderson TR, MArkley JL
MPP, Intrinsically disordered proteins
(Details)(Pubmed ID: 24634806)
Times cited: 18
- Serial femtosecond crystallography of G protein-coupled receptors.
Liu W, Wacker D, Gati C, Han GW, James D, Wang D, Nelson G, Weierstall U, Katritch V, Barty A, Zatsepin NA, Li D, Messerschmidt M, Boutet S, Williams GJ, Koglin JE, Seibert MM, Wang C, Shah ST, Basu S, Fromme R, Kupitz C, Rendek KN, Grotjohann I, Fromme P, Kirian RA, Beyerlein KR, White TA, ChapMAn HN, Caffrey M, Spence JC, Stevens RC, Cherezov V
GPCR+MPID, Science
(Details)(Pubmed ID: 24357322)
PDB ID(s): 4NC3
Times cited: 222
- Structure of a photosynthetic reaction centre determined by serial femtosecond crystallography.
Johansson LC, Arnlund D, Katona G, White TA, Barty A, DePonte DP, ShoeMAn RL, Wickstrand C, SharMA A, Williams GJ, Aquila A, Bogan MJ, CaleMAn C, Davidsson J, Doak RB, Frank M, Fromme R, Galli L, Grotjohann I, Hunter MS, Kassemeyer S, Kirian RA, Kupitz C, Liang M, Lomb L, MAlmerberg E, MArtin AV, Messerschmidt M, Nass K, Redecke L, Seibert MM, Sjöhamn J, Steinbrener J, Stellato F, Wang D, Wahlgren WY, Weierstall U, Westenhoff S, Zatsepin NA, Boutet S, Spence JC, Schlichting I, ChapMAn HN, Fromme P, Neutze R
MPID, Nature communications
(Details)(Pubmed ID: 24352554)
PDB ID(s): 4CAS
Times cited: 55
- HallMArks of a new era in mitochondrial biochemistry.
Pagliarini DJ, Rutter J
MPP, Genes & development
(Details)(Pubmed ID: 24352419)
Times cited: 52
- Polysaccharides utilization in huMAn gut bacterium Bacteroides thetaiotaomicron: comparative genomics reconstruction of metabolic and regulatory networks.
Ravcheev DA, Godzik A, OsterMAn AL, Rodionov DA
JCSG, BMC genomics
(Details)(Pubmed ID: 24330590)
Times cited: 37
- Genetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCR.
Coin I, Katritch V, Sun T, Xiang Z, Siu FY, BeyerMAnn M, Stevens RC, Wang L
GPCR, Cell
(Details)(Pubmed ID: 24290358)
Times cited: 77
- Hepatitis C virus E2 envelope glycoprotein core structure.
Kong L, Giang E, NieusMA T, Kadam RU, Cogburn KE, Hua Y, Dai X, Stanfield RL, Burton DR, Ward AB, Wilson IA, Law M
JCSG, Science
(Details)(Pubmed ID: 24288331)
PDB ID(s): 4MWF
Times cited: 195
- LUD, a new protein doMAin associated with lactate utilization.
Hwang WC, Bakolitsa C, Punta M, Coggill PC, BateMAn A, Axelrod HL, Rawlings ND, Sedova M, Peterson SN, Eberhardt RY, Aravind L, Pascual J, Godzik A
JCSG, BMC Bioinformatics
(Details)(Pubmed ID: 24274019)
PDB ID(s): 2G40
Times cited: 1
- Structure of the S100A4/myosin-IIA complex.
RaMAgopal UA, Dulyaninova NG, Varney KM, Wilder PT, Nallamsetty S, Brenowitz M, Weber DJ, Almo SC, Bresnick AR
NYSGRC, BMC Structural Biology
(Details)(Pubmed ID: 24252706)
PDB ID(s): 4ETO 4HSZ
Times cited: 8
- Filling out the structural MAp of the NTF2-like superfamily.
Eberhardt RY, Chang Y, BateMAn A, Murzin AG, Axelrod HL, Hwang WC, Aravind L
JCSG, BMC Bioinformatics
(Details)(Pubmed ID: 24246060)
PDB ID(s): 3KZT 3K7C 4HYZ
Times cited: 12
- Structural and Biochemical Characterization of the Bilin Lyase CpcS from Thermosynechococcus elongatus.
Kronfel CM, Kuzin AP, Forouhar F, Biswas A, Su M, Lew S, SeetharaMAn J, Xiao R, Everett JK, MA LC, Acton TB, Montelione GT, Hunt JF, Paul CE, DragoMAni TM, Boutaghou MN, Cole RB, Riml C, Alvey RM, Bryant DA, Schluchter WM
NESG, Biochemistry
(Details)(Pubmed ID: 24215428)
Times cited: 11
- High-resolution network biology: connecting sequence with function.
Ryan CJ, CimerMAnčič P, Szpiech ZA, Sali A, Hernandez RD, Krogan NJ
NYSGRC, Nature reviews. Genetics
(Details)(Pubmed ID: 24197012)
Times cited: 41
- An estiMAted 5% of new protein structures solved today represent a new Pfam family.
Mistry J, KloppMAnn E, Rost B, Punta M
NYCOMPS, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 24189229)
Times cited: 9
- Structures of intermediate transport states of ZneA, a Zn(II)/proton antiporter.
Pak JE, Ekendé EN, Kifle EG, O'Connell JD, De Angelis F, TesseMA MB, Derfoufi KM, Robles-Colmenares Y, Robbins RA, GoorMAghtigh E, Vandenbussche G, Stroud RM
CSMP, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 24173033)
PDB ID(s): 4K0E 4K0J
Times cited: 14
- Toroidal structure and DNA cleavage by the CRISPR-associated [4Fe-4S] cluster containing Cas4 nuclease SSO0001 from Sulfolobus solfataricus.
LeMAk S, Beloglazova N, Nocek B, Skarina T, Flick R, Brown G, Popovic A, Joachimiak A, Savchenko A, Yakunin AF
MCSG, Journal of the American Chemical Society
(Details)(Pubmed ID: 24171432)
PDB ID(s): 4IC1
Times cited: 30
- EnzyMAtic Basis for N-Glycan Sialylation: STRUCTURE OF RAT α2,6-SIALYLTRANSFERASE (ST6GAL1) REVEALS CONSERVED AND UNIQUE FEATURES FOR GLYCAN SIALYLATION.
Meng L, Forouhar F, Thieker D, Gao Z, Ramiah A, Moniz H, Xiang Y, SeetharaMAn J, Milaninia S, Su M, Bridger R, Veillon L, Azadi P, Kornhaber G, Wells L, Montelione GT, Woods RJ, Tong L, Moremen KW
NESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 24155237)
Times cited: 52
- X-ray crystal structure of bovine 3 Glu-osteocalcin.
MAlashkevich VN, Almo SC, Dowd TL
NYSGRC, Biochemistry
(Details)(Pubmed ID: 24138653)
PDB ID(s): 4MZZ 1Q8H
Times cited: 9
- Solution NMR structure and histone binding of the PHD doMAin of huMAn MLL5.
LeMAk A, Yee A, Wu H, Yap D, Zeng H, Dombrovski L, Houliston S, Aparicio S, Arrowsmith CH
NESG, PLoS ONE
(Details)(Pubmed ID: 24130829)
Times cited: 11
- Structure and function of a novel LD-carboxypeptidase A involved in peptidoglycan recycling.
Das D, Hervé M, Elsliger MA, Kadam RU, Grant J, Chiu HJ, Knuth MW, Klock HE, Miller MD, Godzik A, Lesley SA, Deacon AM, Mengin-Lecreulx D, Wilson IA
JCSG, Journal of Bacteriology
(Details)(Pubmed ID: 24123814)
PDB ID(s): 3G23
Times cited: 9
- Target prediction for an open access set of compounds active against Mycobacterium tuberculosis.
MArtínez-Jiménez F, Papadatos G, Yang L, Wallace IM, KuMAr V, Pieper U, Sali A, Brown JR, Overington JP, MArti-Renom MA
NYSGRC, PLoS Computational Biology
(Details)(Pubmed ID: 24098102)
Times cited: 31
- Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis.
Ioerger TR, O'MAlley T, Liao R, Guinn KM, Hickey MJ, Mohaideen N, Murphy KC, Boshoff HI, Mizrahi V, Rubin EJ, Sassetti CM, Barry CE, SherMAn DR, Parish T, Sacchettini JC
MTBI, PLoS ONE
(Details)(Pubmed ID: 24086479)
Times cited: 90
- Divergent evolution of protein conforMAtional dynamics in dihydrofolate reductase.
Bhabha G, Ekiert DC, Jennewein M, ZMAsek CM, Tuttle LM, Kroon G, Dyson HJ, Godzik A, Wilson IA, Wright PE
JCSG, Nature Structural & Molecular Biology
(Details)(Pubmed ID: 24077226)
PDB ID(s): 4M6J 4M6K 4M6L
Times cited: 58
- αE-catenin actin-binding doMAin alters actin filament conforMAtion and regulates binding of nucleation and disassembly factors.
Hansen SD, Kwiatkowski AV, Ouyang CY, Liu H, Pokutta S, Watkins SC, VolkMAnn N, Hanein D, Weis WI, Mullins RD, Nelson WJ
CELLMAT, Molecular biology of the cell
(Details)(Pubmed ID: 24068324)
Times cited: 41
- Divergent evolution of ligand binding in the o-succinylbenzoate synthase family.
Odokonyero D, RaguMAni S, Lopez MS, Bonanno JB, Ozerova ND, Woodard DR, MAchala BW, Swaminathan S, Burley SK, Almo SC, Glasner ME
NYSGRC+NYSGXRC, Biochemistry
(Details)(Pubmed ID: 24060347)
PDB ID(s): 2OPJ 2QVH
Times cited: 11
- New LIC vectors for production of proteins from genes containing rare codons.
Eschenfeldt WH, MAkowska-Grzyska M, Stols L, Donnelly MI, Jedrzejczak R, Joachimiak A
MCSG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 24057978)
Times cited: 18
- Discovery of new enzymes and metabolic pathways by using structure and genome context.
Zhao S, KuMAr R, Sakai A, Vetting MW, Wood BM, Brown S, Bonanno JB, Hillerich BS, Seidel RD, Babbitt PC, Almo SC, Sweedler JV, Gerlt JA, Cronan JE, Jacobson MP
EFI+NYSGRC, Nature
(Details)(Pubmed ID: 24056934)
PDB ID(s): 4H2H 2PMQ
Times cited: 71
- NMR structure and MD simulations of the AAA protease intermembrane space doMAin indicates peripheral membrane localization within the hexaoligomer.
Ramelot TA, Yang Y, Sahu ID, Lee HW, Xiao R, Lorigan GA, Montelione GT, Kennedy MA
MPP+NESG, FEBS Letters
(Details)(Pubmed ID: 24055473)
PDB ID(s): 2LNA
Times cited: 7
- Solution NMR structure of CD1104B from pathogenic Clostridium difficile reveals a distinct α-helical architecture and provides first structural representative of protein doMAin family PF14203.
Pulavarti SV, Eletsky A, Lee HW, Acton TB, Xiao R, Everett JK, Prestegard JH, Montelione GT, Szyperski T
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 24048810)
Times cited: 0
- Structure determination and biochemical characterization of a putative HNH endonuclease from Geobacter metallireducens GS-15.
Xu SY, Kuzin AP, SeetharaMAn J, Gutjahr A, Chan SH, Chen Y, Xiao R, Acton TB, Montelione GT, Tong L
NESG, PLoS ONE
(Details)(Pubmed ID: 24039739)
Times cited: 10
- Protein crystallography for aspiring crystallographers or how to avoid pitfalls and traps in MAcromolecular structure determination.
Wlodawer A, Minor W, Dauter Z, Jaskolski M
EFI+MCSG+NYSGRC, FEBS Journal
(Details)(Pubmed ID: 24034303)
Times cited: 45
- Structure of the CCR5 chemokine receptor-HIV entry inhibitor MAraviroc complex.
Tan Q, Zhu Y, Li J, Chen Z, Han GW, Kufareva I, Li T, MA L, Fenalti G, Li J, Zhang W, Xie X, Yang H, Jiang H, Cherezov V, Liu H, Stevens RC, Zhao Q, Wu B
GPCR, Science
(Details)(Pubmed ID: 24030490)
PDB ID(s): 4MBS
Times cited: 351
- Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors.
Lane JR, Chubukov P, Liu W, Canals M, Cherezov V, Abagyan R, Stevens RC, Katritch V
GPCR, Molecular pharmacology
(Details)(Pubmed ID: 24021214)
Times cited: 47
- ConforMAtional stabilization of the membrane embedded targeting doMAin of the lysosoMAl peptide transporter TAPL for solution NMR.
Tumulka F, Roos C, Löhr F, Bock C, Bernhard F, Dötsch V, Abele R
MPSbyNMR, Journal of Biomolecular NMR
(Details)(Pubmed ID: 24013930)
Times cited: 4
- The COMBREX project: design, methodology, and initial results.
Anton BP, Chang YC, Brown P, Choi HP, Faller LL, Guleria J, Hu Z, Klitgord N, Levy-Moonshine A, MAksad A, MAzumdar V, McGettrick M, OsMAni L, Pokrzywa R, Rachlin J, Swaminathan R, Allen B, HousMAn G, Monahan C, Rochussen K, Tao K, Bhagwat AS, Brenner SE, Columbus L, de Crécy-Lagard V, Ferguson D, Fomenkov A, Gadda G, Morgan RD, OsterMAn AL, Rodionov DA, Rodionova IA, Rudd KE, Söll D, Spain J, Xu SY, BateMAn A, Blumenthal RM, Bollinger JM, Chang WS, Ferrer M, Friedberg I, Galperin MY, Gobeill J, Haft D, Hunt J, Karp P, Klimke W, Krebs C, MAcelis D, MAdupu R, MArtin MJ, Miller JH, O'Donovan C, Palsson B, Ruch P, Setterdahl A, Sutton G, Tate J, Yakunin A, Tchigvintsev D, Plata G, Hu J, Greiner R, Horn D, Sjölander K, Salzberg SL, Vitkup D, Letovsky S, Segrè D, DeLisi C, Roberts RJ, Steffen M, Kasif S
NESG, PLoS Biology
(Details)(Pubmed ID: 24013487)
Times cited: 34
- Recommendations of the wwPDB NMR Validation Task Force.
Montelione GT, Nilges M, Bax A, Güntert P, HerrMAnn T, Richardson JS, Schwieters CD, Vranken WF, Vuister GW, Wishart DS, BerMAn HM, Kleywegt GJ, MArkley JL
NESG, Structure
(Details)(Pubmed ID: 24010715)
Times cited: 67
- Two Pfam protein families characterized by a crystal structure of protein lpg2210 from Legionella pneumophila.
Coggill P, Eberhardt RY, Finn RD, Chang Y, Jaroszewski L, Godzik A, Das D, Xu Q, Axelrod HL, Aravind L, Murzin AG, BateMAn A
JCSG, BMC Bioinformatics
(Details)(Pubmed ID: 24004689)
PDB ID(s): 4G2A
Times cited: 1
- Structural, Functional, and Inhibition Studies of a Gcn5-related N-Acetyltransferase (GNAT) Superfamily Protein PA4794 A NEW C-TERMINAL LYSINE PROTEIN ACETYLTRANSFERASE FROM PSEUDOMONAS AERUGINOSA
MAjorek KA, Kuhn ML, Chruszcz M, Anderson WF, Minor W
CSGID+MCSG, Journal of Biological Chemistry
(Details)(Pubmed ID: 24003232)
PDB ID(s): 4KUA 3PGP 4KUB 4L89 4L8A 4KLV 4KOT 4KOW 4KOX 4KOV 4KOU 4KOY 4KOR 4KOS 4KLW
Times cited: 23
- Structure of isochorisMAte synthase DhbC from Bacillus anthracis.
DoMAgalski MJ, Tkaczuk KL, Chruszcz M, Skarina T, Onopriyenko O, Cymborowski M, Grabowski M, Savchenko A, Minor W
CSGID, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 23989140)
Times cited: 0
- A bidirectional system for the dynamic sMAll molecule control of intracellular fusion proteins.
Neklesa TK, Noblin DJ, Kuzin A, Lew S, SeetharaMAn J, Acton TB, Kornhaber G, Xiao R, Montelione GT, Tong L, Crews CM
NESG, ACS Chemical Biology
(Details)(Pubmed ID: 23978068)
Times cited: 12
- Comparative phosphoproteomics reveals components of host cell invasion and post-transcriptional regulation during Francisella infection.
Nakayasu ES, Tempel R, Cambronne XA, Petyuk VA, Jones MB, Gritsenko MA, Monroe ME, Yang F, Smith RD, Adkins JN, Heffron F
PCSEP, Molecular & Cellular Proteomics
(Details)(Pubmed ID: 23970565)
Times cited: 11
- Solution NMR structures provide first structural coverage of the large protein doMAin family PF08369 and complementary structural coverage of dark operative protochlorophyllide oxidoreductase complexes.
Pulavarti SV, He Y, FeldMAnn EA, Eletsky A, Acton TB, Xiao R, Everett JK, Montelione GT, Kennedy MA, Szyperski T
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 23963952)
Times cited: 0
- Biophysical analysis of the putative acetyltransferase SACOL2570 from methicillin-resistant Staphylococcus aureus.
Luo HB, Knapik AA, Petkowski JJ, DeMAs M, Shumilin IA, Zheng H, Chruszcz M, Minor W
CSGID, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 23963951)
PDB ID(s): 3FTT
Times cited: 1
- Diverse secreted effectors are required for Salmonella persistence in a mouse infection model.
Kidwai AS, Mushamiri I, NieMAnn GS, Brown RN, Adkins JN, Heffron F
PCSEP, PLoS ONE
(Details)(Pubmed ID: 23950998)
Times cited: 12
- HuMAn Mitochondrial Chaperone (mtHSP70) and Cysteine Desulfurase (NFS1) Bind Preferentially to the Disordered ConforMAtion whereas Co-chaperone (HSC20) Binds to the Structured ConforMAtion of the Iron-Sulfur Cluster Scaffold Protein (ISCU).
Cai K, Frederick RO, Kim JH, Reinen NM, Tonelli M, MArkley JL
MPP, Journal of Biological Chemistry
(Details)(Pubmed ID: 23940031)
Times cited: 29
- Branched signal wiring of an essential bacterial cell-cycle phosphotransfer protein.
Blair JA, Xu Q, Childers WS, MAthews II, Kern JW, Eckart M, Deacon AM, Shapiro L
JCSG, Structure
(Details)(Pubmed ID: 23932593)
PDB ID(s): 4FMT
Times cited: 8
- Computational design of an unnatural amino acid dependent metalloprotein with atomic level accuracy.
Mills JH, Khare SD, Bolduc JM, Forouhar F, Mulligan VK, Lew S, SeetharaMAn J, Tong L, Stoddard BL, Baker D
NESG, Journal of the American Chemical Society
(Details)(Pubmed ID: 23924187)
Times cited: 56
- Microcompartments and protein MAchines in prokaryotes.
Saier MH
TransportPDB, Journal of Molecular Microbiology and Biotechnology
(Details)(Pubmed ID: 23920489)
Times cited: 10
- Cross-linking and MAss spectrometry methodologies to facilitate structural biology: finding a path through the MAze.
Merkley ED, Cort JR, Adkins JN
PCSEP, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 23917845)
Times cited: 16
- AutoMAted identification of functional dynamic contact networks from X-ray crystallography.
van den Bedem H, Bhabha G, Yang K, Wright PE, Fraser JS
JCSG, Nature Methods
(Details)(Pubmed ID: 23913260)
Times cited: 68
- Analysis of periplasmic sensor doMAins from Anaeromyxobacter dehalogenans 2CP-C: Structure of one sensor doMAin from a histidine kinase and another from a chemotaxis protein.
Pokkuluri PR, Dwulit-Smith J, Duke NE, Wilton R, MAck JC, Bearden J, Rakowski E, Babnigg G, SzurMAnt H, Joachimiak A, Schiffer M
MCSG, MicrobiologyOpen
(Details)(Pubmed ID: 23897711)
PDB ID(s): 4K08 4K0D
Times cited: 2
- PDBStat: a universal restraint converter and restraint analysis software package for protein NMR.
Tejero R, Snyder D, MAo B, Aramini JM, Montelione GT
NESG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 23897031)
Times cited: 21
- Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica.
Kube M, Chernikova TN, Al-RaMAhi Y, Beloqui A, Lopez-Cortez N, Guazzaroni ME, Heipieper HJ, Klages S, Kotsyurbenko OR, Langer I, Nechitaylo TY, Lünsdorf H, Fernández M, Juárez S, Ciordia S, Singer A, Kagan O, Egorova O, Alain Petit P, Stogios P, Kim Y, Tchigvintsev A, Flick R, Denaro R, Genovese M, Albar JP, Reva ON, MArtínez-GoMAriz M, Tran H, Ferrer M, Savchenko A, Yakunin AF, Yakimov MM, Golyshina OV, Reinhardt R, Golyshin PN
MCSG, Nature communications
(Details)(Pubmed ID: 23877221)
PDB ID(s): 3QVM 3QVQ 3M16 3LQY 3LNP 3V77 3VCR 3IRU 3LMB
Times cited: 57
- Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
Still AJ, Floyd BJ, Hebert AS, BingMAn CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ
MPP, Journal of Biological Chemistry
(Details)(Pubmed ID: 23864654)
Times cited: 60
- Structure of the huMAn glucagon class B G-protein-coupled receptor.
Siu FY, He M, de Graaf C, Han GW, Yang D, Zhang Z, Zhou C, Xu Q, Wacker D, Joseph JS, Liu W, Lau J, Cherezov V, Katritch V, Wang MW, Stevens RC
GPCR+JCSG, Nature
(Details)(Pubmed ID: 23863937)
PDB ID(s): 4L6R
Times cited: 231
- Acetylation of the Response Regulator RcsB Controls Transcription from a SMAll RNA Promoter.
Hu LI, Chi BK, Kuhn ML, Filippova EV, Walker-Peddakotla AJ, Bäsell K, Becher D, Anderson WF, AntelMAnn H, Wolfe AJ
CSGID, Journal of Bacteriology
(Details)(Pubmed ID: 23852870)
Times cited: 51
- The hepatitis B virus preS1 doMAin hijacks host trafficking proteins by motif mimicry.
Jürgens MC, Vörös J, Rautureau GJ, Shepherd DA, Pye VE, Muldoon J, Johnson CM, Ashcroft AE, Freund SM, Ferguson N
MPID, Nature Chemical Biology
(Details)(Pubmed ID: 23851574)
PDB ID(s): 4BCX 3ZHF 2YMT
Times cited: 14
- Crystal structure of the ligand-binding form of nanoRNase from Bacteroides fragilis, a member of the DHH/DHHA1 phosphoesterase family of proteins.
Uemura Y, Nakagawa N, WakaMAtsu T, Kim K, Montelione GT, Hunt JF, Kuramitsu S, MAsui R
NESG, FEBS Letters
(Details)(Pubmed ID: 23851074)
Times cited: 9
- Computational design of a protein-based enzyme inhibitor.
Procko E, HedMAn R, Hamilton K, SeetharaMAn J, FleishMAn SJ, Su M, Aramini J, Kornhaber G, Hunt JF, Tong L, Montelione GT, Baker D
NESG, Journal of Molecular Biology
(Details)(Pubmed ID: 23827138)
Times cited: 42
- Role of the zinc uptake ABC transporter of Moraxella catarrhalis in persistence in the respiratory tract.
Murphy TF, Brauer AL, Kirkham C, Johnson A, Koszelak-Rosenblum M, MAlkowski MG
MPSBC, Infection and immunity
(Details)(Pubmed ID: 23817618)
Times cited: 16
- Serum albumins-Unusual allergens.
Chruszcz M, Mikolajczak K, MAnk N, MAjorek KA, Porebski PJ, Minor W
NYSGRC, Biochimica et biophysica acta
(Details)(Pubmed ID: 23811341)
Times cited: 43
- Sulfopeptide probes of the CXCR4/CXCL12 interface reveal oligomer-specific contacts and chemokine allostery.
Ziarek JJ, GetschMAn AE, Butler SJ, Taleski D, Stephens B, Kufareva I, Handel TM, Payne RJ, VolkMAn BF
CHSAM+GPCR, ACS Chemical Biology
(Details)(Pubmed ID: 23802178)
PDB ID(s): 1SDF 2K01 2K05
Times cited: 33
- Robust structural analysis of native biological MAcromolecules from multi-crystal anoMAlous diffraction data.
Liu Q, Liu Q, Hendrickson WA
NYCOMPS, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 23793158)
Times cited: 50
- Crystallographic data processing for free-electron laser sources.
White TA, Barty A, Stellato F, Holton JM, Kirian RA, Zatsepin NA, ChapMAn HN
CSMP, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 23793149)
Times cited: 73
- Crystal Structures of MAlonyl-Coenzyme A Decarboxylase Provide Insights into Its Catalytic Mechanism and Disease-Causing Mutations.
Froese DS, Forouhar F, Tran TH, VollMAr M, Kim YS, Lew S, Neely H, SeetharaMAn J, Shen Y, Xiao R, Acton TB, Everett JK, Cannone G, Puranik S, Savitsky P, Krojer T, Pilka ES, Kiyani W, Lee WH, MArsden BD, von Delft F, Allerston CK, Spagnolo L, Gileadi O, Montelione GT, OpperMAnn U, Yue WW, Tong L
NESG, Structure
(Details)(Pubmed ID: 23791943)
Times cited: 11
- Conserved aroMAtic residue confers cation selectivity in claudin-2 and claudin-10b.
Li J, Zhuo M, Pei L, Yu AS
TJMP, Journal of Biological Chemistry
(Details)(Pubmed ID: 23760508)
Times cited: 16
- Molecular basis for benzodiazepine agonist action at the type 1 cholecystokinin receptor.
HarikuMAr KG, Cawston EE, Lam PC, Patil A, Orry A, Henke BR, Abagyan R, Christopoulos A, Sexton PM, Miller LJ
CHSAM+GPCR, Journal of Biological Chemistry
(Details)(Pubmed ID: 23754289)
Times cited: 9
- Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation.
Goult BT, Xu XP, Gingras AR, Swift M, Patel B, Bate N, Kopp PM, Barsukov IL, Critchley DR, VolkMAnn N, Hanein D
CELLMAT, Journal of Structural Biology
(Details)(Pubmed ID: 23726984)
PDB ID(s): 3DYJ
Times cited: 41
- Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120.
Kong L, Lee JH, Doores KJ, Murin CD, Julien JP, McBride R, Liu Y, MArozsan A, Cupo A, Klasse PJ, Hoffenberg S, Caulfield M, King CR, Hua Y, Le KM, Khayat R, Deller MC, Clayton T, Tien H, Feizi T, Sanders RW, Paulson JC, Moore JP, Stanfield RL, Burton DR, Ward AB, Wilson IA
JCSG, Nature Structural & Molecular Biology
(Details)(Pubmed ID: 23708606)
PDB ID(s): 4JM4 4JM2
Times cited: 196
- Mice transgenic for CD4-specific huMAn CD4, CCR5 and cyclin T1 expression: a new model for investigating HIV-1 transmission and treatment efficacy.
Seay K, Qi X, Zheng JH, Zhang C, Chen K, Dutta M, Deneroff K, Ochsenbauer C, Kappes JC, LittMAn DR, Goldstein H
NYSGRC, PLoS ONE
(Details)(Pubmed ID: 23691059)
Times cited: 21
- Structural basis for alternating access of a eukaryotic calcium/proton exchanger.
Waight AB, Pedersen BP, Schlessinger A, Bonomi M, Chau BH, Roe-Zurz Z, RisenMAy AJ, Sali A, Stroud RM
CSMP, Nature
(Details)(Pubmed ID: 23685453)
PDB ID(s): 4K1C
Times cited: 47
- Salmonella enterica MTAN at 1.36 Å resolution: a structure-based design of tailored transition state analogs.
Haapalainen AM, ThoMAs K, Tyler PC, Evans GB, Almo SC, Schramm VL
NYSGRC, Structure
(Details)(Pubmed ID: 23685211)
PDB ID(s): 4F1W 4F2W 4F3K 4F3C
Times cited: 8
- Modeling proteins using a super-secondary structure library and NMR chemical shift inforMAtion.
Menon V, Vallat BK, Dybas JM, Fiser A
NYSGRC, Structure
(Details)(Pubmed ID: 23685209)
Times cited: 9
- [2Fe-2S]-ferredoxin binds directly to cysteine desulfurase and supplies an electron for iron-sulfur cluster assembly but is displaced by the scaffold protein or bacterial frataxin.
Kim JH, Frederick RO, Reinen NM, Troupis AT, MArkley JL
MPP, Journal of the American Chemical Society
(Details)(Pubmed ID: 23682711)
Times cited: 42
- Structural representative of the protein family PF14466 has a new fold and establishes links with the C2 and PLAT doMAins from the widely distant Pfams PF00168 and PF01477.
Serrano P, Geralt M, Mohanty B, Wüthrich K
JCSG, Protein Science
(Details)(Pubmed ID: 23681886)
PDB ID(s): 2LG7 2LGE
Times cited: 4
- Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function.
Kim J, Xiao H, Bonanno JB, KalyanaraMAn C, Brown S, Tang X, Al-Obaidi NF, Patskovsky Y, Babbitt PC, Jacobson MP, Lee YS, Almo SC
NYSGRC+EFI+NYSGXRC, Nature
(Details)(Pubmed ID: 23676670)
PDB ID(s): 4GEK
Times cited: 29
- Optimization of Benzoxazole-Based Inhibitors of Cryptosporidium parvum Inosine 5'-Monophosphate Dehydrogenase.
Gorla SK, Kavitha M, Zhang M, Chin JE, Liu X, Striepen B, MAkowska-Grzyska M, Kim Y, Joachimiak A, Hedstrom L, Cuny GD
CSGID, Journal of Medicinal Chemistry
(Details)(Pubmed ID: 23668331)
PDB ID(s): 4IXH
Times cited: 45
- Structural and Functional Characterization of CalS11, a TDP-Rhamnose 3'-O-Methyltransferase Involved in Calicheamicin Biosynthesis.
Singh S, Chang A, Helmich KE, BingMAn CA, Wrobel RL, Beebe ET, MAkino SI, Aceti DJ, Dyer K, Hura GL, Sunkara M, Morris AJ, Phillips GN, Thorson JS
NATPRO+, ACS Chemical Biology
(Details)(Pubmed ID: 23662776)
PDB ID(s): 3TOS 4GF5
Times cited: 7
- Evaluation of selected binding doMAins for the analysis of ubiquitinated proteomes.
Nakayasu ES, Ansong C, Brown JN, Yang F, Lopez-Ferrer D, Qian WJ, Smith RD, Adkins JN
PCSEP, Journal of the American Society for Mass Spectrometry
(Details)(Pubmed ID: 23649778)
Times cited: 6
- Evolutionary relationships of ATP-Binding Cassette (ABC) uptake porters.
Zheng WH, VästerMArk Å, Shlykov MA, Reddy V, Sun EI, Saier MH
TransportPDB, BMC microbiology
(Details)(Pubmed ID: 23647830)
Times cited: 14
- Multi-omic data integration links deleted in breast cancer 1 (DBC1) degradation to chroMAtin remodeling in inflamMAtory response.
Nakayasu ES, Brown RN, Ansong C, Sydor MA, Imtiaz S, Mihai C, Sontag R, Hixson KK, Monroe ME, Sobreira TJ, Orr G, Petyuk VA, Yang F, Smith RD, Adkins JN
PCSEP, Molecular & Cellular Proteomics
(Details)(Pubmed ID: 23639857)
Times cited: 2
- Reversible folding of huMAn peripheral myelin protein 22, a tetraspan membrane protein.
Schlebach JP, Peng D, Kroncke BM, Mittendorf KF, Narayan M, Carter BD, Sanders CR
MPSbyNMR, Biochemistry
(Details)(Pubmed ID: 23639031)
Times cited: 21
- Mutations in FLS2 Ser-938 dissect signaling activation in FLS2-mediated Arabidopsis immunity.
Cao Y, Aceti DJ, Sabat G, Song J, MAkino S, Fox BG, Bent AF
TMPC, PLos Pathogens
(Details)(Pubmed ID: 23637603)
Times cited: 29
- Structure of the huMAn smoothened receptor bound to an antitumour agent.
Wang C, Wu H, Katritch V, Han GW, Huang XP, Liu W, Siu FY, Roth BL, Cherezov V, Stevens RC
GPCR, Nature
(Details)(Pubmed ID: 23636324)
PDB ID(s): 4JKV
Times cited: 270
- The Protein Model Portal--a comprehensive resource for protein structure and model inforMAtion.
Haas J, Roth S, Arnold K, Kiefer F, Schmidt T, Bordoli L, Schwede T
PSISBKB, Database : the journal of biological databases and curation
(Details)(Pubmed ID: 23624946)
Times cited: 1
- Crystal structure of the protein from Arabidopsis thaliana gene At5g06450, a putative DnaQ-like exonuclease doMAin-containing protein with homohexameric assembly.
Smith DW, Han MR, Park JS, Kim KR, Yeom T, Lee JY, Kim do J, BingMAn CA, Kim HJ, Jo K, Han BW, Phillips GN
NATPRO+NatPro, Proteins
(Details)(Pubmed ID: 23616405)
PDB ID(s): 1VK0
Times cited: 5
- Structural and functional characterization of solute binding proteins for aroMAtic compounds derived from lignin: p-couMAric acid and related aroMAtic acids.
Tan K, Chang C, Cuff M, Osipiuk J, Landorf E, MAck JC, Zerbs S, Joachimiak A, Collart FR
MCSG+PCSEP, Proteins
(Details)(Pubmed ID: 23606130)
PDB ID(s): 3SG0 4DQD 3UKJ 4EYO 4EYQ 3TX6 4F8J 4FB4 3UK0
Times cited: 9
- Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
Shukla AK, MAnglik A, Kruse AC, Xiao K, Reis RI, Tseng WC, Staus DP, Hilger D, Uysal S, Huang LY, Paduch M, Tripathi-Shukla P, Koide A, Koide S, Weis WI, Kossiakoff AA, Kobilka BK, Lefkowitz RJ
CEBS, Nature
(Details)(Pubmed ID: 23604254)
PDB ID(s): 4JQI
Times cited: 169
- Structure and T cell inhibition properties of B7 family member, B7-H3.
Vigdorovich V, RaMAgopal UA, Lázár-Molnár E, Sylvestre E, Lee JS, Hofmeyer KA, Zang X, Nathenson SG, Almo SC
IFN+NYSGRC, Structure
(Details)(Pubmed ID: 23583036)
PDB ID(s): 4I0K
Times cited: 26
- Functional classification of immune regulatory proteins.
Rubinstein R, RaMAgopal UA, Nathenson SG, Almo SC, Fiser A
IFN+NYSGRC, Structure
(Details)(Pubmed ID: 23583034)
Times cited: 10
- Structure and Function of the DUF2233 DoMAin in Bacteria and in the HuMAn MAnnose 6-Phosphate Uncovering Enzyme.
Das D, Lee WS, Grant JC, Chiu HJ, Farr CL, Vance J, Klock HE, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Kornfeld S, Wilson IA
JCSG, Journal of Biological Chemistry
(Details)(Pubmed ID: 23572527)
PDB ID(s): 3OHG
Times cited: 3
- New sub-family of lysozyme-like proteins shows no catalytic activity crystallographic and biochemical study of STM3605 protein from Salmonella Typhimurium
Michalska K, Brown RN, Li H, Jedrzejczak R, NieMAnn GS, Heffron F, Cort JR, Adkins JN, Babnigg G, Joachimiak A,
MCSG+PCSEP, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 23572252)
PDB ID(s): 4EVX
Times cited: 2
- Rational design of a ligand-controlled protein conforMAtional switch.
Dagliyan O, Shirvanyants D, Karginov AV, Ding F, Fee L, Chandrasekaran SN, Freisinger CM, Smolen GA, Huttenlocher A, Hahn KM, Dokholyan NV
CELLMAT, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 23569285)
Times cited: 44
- Improved expression and purification of sigMA 1 receptor fused to MAltose binding protein by alteration of linker sequence.
Gromek KA, Meddaugh HR, Wrobel RL, Suchy FP, BingMAn CA, Primm JG, Fox BG
TMPC, Protein Expression and Purification
(Details)(Pubmed ID: 23562661)
Times cited: 9
- Patch-clamp characterization of the MscS-like mechanosensitive channel from Silicibacter pomeroyi.
Petrov E, Palanivelu D, Constantine M, Rohde PR, Cox CD, Nomura T, Minor DL, MArtinac B
CSMP, Biophysical Journal
(Details)(Pubmed ID: 23561519)
Times cited: 15
- Structures of the noncanonical RNA ligase RtcB reveal the mechanism of histidine guanylylation.
Desai KK, BingMAn CA, Phillips GN, Raines RT
NATPRO+NatPro, Biochemistry
(Details)(Pubmed ID: 23560983)
PDB ID(s): 4ISZ 4IT0 4ISJ
Times cited: 21
- Two Fe-S clusters catalyze sulfur insertion by radical-SAM methylthiotransferases.
Forouhar F, Arragain S, Atta M, Gambarelli S, Mouesca JM, Hussain M, Xiao R, Kieffer-Jaquinod S, SeetharaMAn J, Acton TB, Montelione GT, Mulliez E, Hunt JF, Fontecave M
NESG, Nature Chemical Biology
(Details)(Pubmed ID: 23542644)
Times cited: 56
- Crystal structure of a eukaryotic phosphate transporter.
Pedersen BP, KuMAr H, Waight AB, RisenMAy AJ, Roe-Zurz Z, Chau BH, Schlessinger A, Bonomi M, Harries W, Sali A, Johri AK, Stroud RM
CSMP, Nature
(Details)(Pubmed ID: 23542591)
PDB ID(s): 4J05
Times cited: 112
- Structure of the integral membrane protein CAAX protease Ste24p.
Pryor EE, Horanyi PS, Clark KM, Fedoriw N, Connelly SM, Koszelak-Rosenblum M, Zhu G, MAlkowski MG, Wiener MC, Dumont ME
MPSBC, Science
(Details)(Pubmed ID: 23539602)
PDB ID(s): 4IL3
Times cited: 45
- Crystal structure of huMAn Karyopherin β2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2.
Soniat M, SampathkuMAr P, Collett G, Gizzi AS, Banu RN, Bhosle RC, ChaMAla S, Chowdhury S, Fiser A, Glenn AS, Hammonds J, Hillerich B, Khafizov K, Love JD, MAtikainen B, Seidel RD, Toro R, Rajesh KuMAr P, Bonanno JB, Chook YM, Almo SC
NPCXstals+NYSGRC, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 23535894)
PDB ID(s): 4JLQ
Times cited: 8
- Crystal structure of SsfS6, the putative C-glycosyltransferase involved in SF2575 biosynthesis.
Wang F, Zhou M, Singh S, YennaMAlli RM, BingMAn CA, Thorson JS, Phillips GN
NATPRO+NatPro, Proteins
(Details)(Pubmed ID: 23526584)
PDB ID(s): 4FZR 4G2T
Times cited: 14
- GH1-family 6-P-β-glucosidases from huMAn microbiome lactic acid bacteria.
Michalska K, Tan K, Li H, Hatzos-Skintges C, Bearden J, Babnigg G, Joachimiak A
MCSG, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 23519420)
PDB ID(s): 3QOM 4GZE 3PN8 4F66 4F79
Times cited: 12
- Structural basis for molecular recognition at serotonin receptors.
Wang C, Jiang Y, MA J, Wu H, Wacker D, Katritch V, Han GW, Liu W, Huang XP, Vardy E, McCorvy JD, Gao X, Zhou XE, Melcher K, Zhang C, Bai F, Yang H, Yang L, Jiang H, Roth BL, Cherezov V, Stevens RC, Xu HE
GPCR, Science
(Details)(Pubmed ID: 23519210)
PDB ID(s): 4IAR 4IAQ
Times cited: 248
- DNA nanotubes for NMR structure determination of membrane proteins.
Bellot G, McClintock MA, Chou JJ, Shih WM
MPSbyNMR, Nature Protocols
(Details)(Pubmed ID: 23518667)
Times cited: 29
- Biological and biochemical characterization of HIV-1 Gag/dgp41 virus-like particles expressed in Nicotiana benthamiana.
Kessans SA, Linhart MD, MAtoba N, Mor T
MPID, Plant biotechnology journal
(Details)(Pubmed ID: 23506331)
Times cited: 13
- A pipeline for comprehensive and autoMAted processing of electron diffraction data in IPLT.
Schenk AD, Philippsen A, Engel A, Walz T
TEMIMPS, Journal of Structural Biology
(Details)(Pubmed ID: 23500887)
Times cited: 4
- Electron Transfer Mechanism of the Rieske Protein from Thermus thermophilus from Solution Nuclear MAgnetic Resonance Investigations.
Hsueh KL, Tonelli M, Cai K, Westler WM, MArkley JL
MPP, Biochemistry
(Details)(Pubmed ID: 23480240)
Times cited: 5
- Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria.
Chao MC, Kieser KJ, Minami S, MAvrici D, Aldridge BB, Fortune SM, Alber T, Rubin EJ
MTBI, PLos Pathogens
(Details)(Pubmed ID: 23468634)
Times cited: 22
- Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity.
Ho MC, Wilczek C, Bonanno JB, Xing L, Seznec J, MAtsui T, Carter LG, Onikubo T, KuMAr PR, Chan MK, Brenowitz M, Cheng RH, Reimer U, Almo SC, Shechter D
NYSGRC, PLoS ONE
(Details)(Pubmed ID: 23451136)
Times cited: 48
- Benjamin Franklin, Philadelphia's favorite son, was a membrane biophysicist.
Wang DN, Stieglitz H, MArden J, Tamm LK
NYCOMPS, Biophysical Journal
(Details)(Pubmed ID: 23442850)
Times cited: 3
- Insight into the sporulation phosphorelay: Crystal structure of the sensor doMAin of Bacillus subtilis histidine kinase, KinD
Wu R, Gu M, Wilton R, Babnigg G, Kim Y, Pokkuluri PR, SzurMAnt H, Joachimiak A, Schiffer M.
MCSG, Protein Science
(Details)(Pubmed ID: 23436677)
PDB ID(s): 4DBJ 4DHA 4DBI 4DAK
Times cited: 20
- Protein structure based prediction of catalytic residues.
Fajardo JE, Fiser A
NYSGRC, BMC Bioinformatics
(Details)(Pubmed ID: 23433045)
Times cited: 14
- Mixed-isotope labeling with LC-IMS-MS for characterization of protein-protein interactions by chemical cross-linking.
Merkley ED, Baker ES, Crowell KL, Orton DJ, Taverner T, Ansong C, Ibrahim YM, Burnet MC, Cort JR, Anderson GA, Smith RD, Adkins JN
PCSEP, Journal of the American Society for Mass Spectrometry
(Details)(Pubmed ID: 23423792)
Times cited: 18
- The diversity of allosteric controls at the gateway to aroMAtic amino acid biosynthesis.
Light SH, Anderson WF
CSGID, Protein Science
(Details)(Pubmed ID: 23400945)
Times cited: 18
- RNA type III secretion signals that require Hfq.
NieMAnn GS, Brown RN, Mushamiri IT, Nguyen NT, Taiwo R, Stufkens A, Smith RD, Adkins JN, McDermott JE, Heffron F
PCSEP, Journal of Bacteriology
(Details)(Pubmed ID: 23396917)
Times cited: 13
- Coordinating the impact of structural genomics on the huMAn α-helical transmembrane proteome.
Pieper U, Schlessinger A, KloppMAnn E, Chang GA, Chou JJ, Dumont ME, Fox BG, Fromme P, Hendrickson WA, MAlkowski MG, Rees DC, Stokes DL, Stowell MH, Wiener MC, Rost B, Stroud RM, Stevens RC, Sali A
CSMP+GPCR+MPID+MPSBC+MPSbyNMR+NYCOMPS+TEMIMPS+TMPC+TransportPDB, Nature Structural & Molecular Biology
(Details)(Pubmed ID: 23381628)
Times cited: 43
- The quiet renaissance of protein nuclear MAgnetic resonance.
Barrett PJ, Chen J, Cho MK, Kim JH, Lu Z, MAthew S, Peng D, Song Y, Van Horn WD, Zhuang T, Sönnichsen FD, Sanders CR
MPSbyNMR, Biochemistry
(Details)(Pubmed ID: 23368985)
Times cited: 23
- NDM-1, the ultiMAte promiscuous enzyme: substrate recognition and catalytic mechanism.
Kim Y, Cunningham MA, Mire J, Tesar C, Sacchettini J, Joachimiak A
MCSG+MTBI, FASEB Journal
(Details)(Pubmed ID: 23363572)
PDB ID(s): 4HL2 4H0D 4HL1 4HKY
Times cited: 53
- Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries.
DeJesus MA, Zhang YJ, Sassetti CM, Rubin EJ, Sacchettini JC, Ioerger TR
MTBI, Bioinformatics
(Details)(Pubmed ID: 23361328)
Times cited: 28
- A Pathogen Type III Effector with a Novel E3 Ubiquitin Ligase Architecture.
Singer AU, Schulze S, Skarina T, Xu X, Cui H, Eschen-Lippold L, Egler M, SrikuMAr T, Raught B, Lee J, Scheel D, Savchenko A, Bonas U
MCSG, PLos Pathogens
(Details)(Pubmed ID: 23359647)
PDB ID(s): 4FCG 4FC9
Times cited: 40
- Integron gene cassettes: a repository of novel protein folds with distinct interaction sites.
Sureshan V, Deshpande CN, Boucher Y, Koenig JE, Stokes HW, Harrop SJ, Curmi PM, MAbbutt BC
MCSG, PLoS ONE
(Details)(Pubmed ID: 23349695)
PDB ID(s): 3FLY 3FXH 3FY6 3IF4 3IMO 3JRT
Times cited: 8
- Inward-facing conforMAtion of the zinc transporter YiiP revealed by cryoelectron microscopy.
Coudray N, Valvo S, Hu M, Lasala R, Kim C, Vink M, Zhou M, Provasi D, Filizola M, Tao J, Fang J, Penczek PA, Ubarretxena-Belandia I, Stokes DL
TEMIMPS, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 23341604)
PDB ID(s): 3J1Z
Times cited: 42
- Metamorphic Protein IscU Alternates ConforMAtions in the Course of its Role as the Scaffold Protein for Iron-Sulfur Cluster Biosynthesis and Delivery.
MArkley JL, Kim JH, Dai Z, Bothe JR, Cai K, Frederick RO, Tonelli M
MPP, FEBS Letters
(Details)(Pubmed ID: 23333622)
PDB ID(s): 2L4X
Times cited: 42
- Computational design of enone-binding proteins with catalytic activity for the morita-baylis-hillMAn reaction.
Bjelic S, Nivón LG, Celebi-Ölçüm N, Kiss G, Rosewall CF, Lovick HM, Ingalls EL, Gallaher JL, SeetharaMAn J, Lew S, Montelione GT, Hunt JF, Michael FE, Houk KN, Baker D
NESG, ACS Chemical Biology
(Details)(Pubmed ID: 23330600)
Times cited: 31
- Structure of the Bifunctional Acyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double-Hot-Dog Fold.
LohMAn JR, BingMAn CA, Phillips GN, Shen B
NATPRO+NatPro, Biochemistry
(Details)(Pubmed ID: 23320975)
PDB ID(s): 4HZN 4HZO 4HZP
Times cited: 15
- Cowpox virus employs a two-pronged strategy to outflank MHCI antigen presentation.
McCoy WH, Wang X, YokoyaMA WM, Hansen TH, Fremont DH
CSGID, Molecular immunology
(Details)(Pubmed ID: 23312338)
PDB ID(s): 4HKJ
Times cited: 9
- Structures of apo- and ssDNA-bound YdbC from Lactococcus lactis uncover the function of protein doMAin family DUF2128 and expand the single-stranded DNA-binding doMAin proteome.
Rossi P, Barbieri CM, Aramini JM, Bini E, Lee HW, Janjua H, Xiao R, Acton TB, Montelione GT
NESG, Nucleic Acids Research
(Details)(Pubmed ID: 23303792)
Times cited: 3
- Function of Shaker potassium channels produced by cell-free translation upon injection into Xenopus oocytes.
Jarecki BW, MAkino S, Beebe ET, Fox BG, Chanda B
TMPC, Scientific reports
(Details)(Pubmed ID: 23301161)
Times cited: 14
- Environment-sensing merocyanine dyes for live cell iMAging applications.
MAcNevin CJ, Gremyachinskiy D, Hsu CW, Li L, Rougie M, Davis TT, Hahn KM
CELLMAT, Bioconjugate chemistry
(Details)(Pubmed ID: 23297747)
Times cited: 27
- HeMAgglutinin homologue from H17N10 bat influenza virus exhibits divergent receptor-binding and pH-dependent fusion activities.
Zhu X, Yu W, McBride R, Li Y, Chen LM, Donis RO, Tong S, Paulson JC, Wilson IA
JCSG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 23297216)
PDB ID(s): 4I78
Times cited: 88
- Generating conforMAtion-specific synthetic antibodies to trap proteins in selected functional states.
Paduch M, Koide A, Uysal S, Rizk SS, Koide S, Kossiakoff AA
CEBS, Methods
(Details)(Pubmed ID: 23280336)
Times cited: 29
- Allosteric control in a metalloprotein draMAtically alters function.
Baxter EL, Zuris JA, Wang C, Vo PL, Axelrod HL, Cohen AE, Paddock ML, Nechushtai R, Onuchic JN, Jennings PA
JCSG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 23271805)
PDB ID(s): 4EZF 4F28 4F1E 4F2C
Times cited: 14
- 3D iMAging and quantitative analysis of sMAll solubilized membrane proteins and their complexes by transmission electron microscopy.
Vahedi-Faridi A, Jastrzebska B, Palczewski K, Engel A
TEMIMPS, Journal of electron microscopy
(Details)(Pubmed ID: 23267047)
Times cited: 13
- Cell-free production of integral membrane aspartic acid proteases reveals zinc-dependent methyltransferase activity of the Pseudomonas aeruginosa prepilin peptidase PilD.
Aly KA, Beebe ET, Chan CH, Goren MA, Sepúlveda C, MAkino S, Fox BG, Forest KT
TMPC, MicrobiologyOpen
(Details)(Pubmed ID: 23255525)
Times cited: 11
- The GPCR Network: a large-scale collaboration to determine huMAn GPCR structure and function.
Stevens RC, Cherezov V, Katritch V, Abagyan R, Kuhn P, Rosen H, Wüthrich K
GPCR, Nature reviews. Drug discovery
(Details)(Pubmed ID: 23237917)
Times cited: 153
- Utilization of protein intrinsic disorder knowledge in structural proteomics.
Oldfield CJ, Xue B, Van YY, Ulrich EL, MArkley JL, Dunker AK, Uversky VN
CESG, Biochimica et biophysica acta
(Details)(Pubmed ID: 23232152)
Times cited: 24
- Structure and activity of the NAD(P)+-dependent succinate semialdehyde dehydrogenase YneI from Salmonella typhimurium.
Zheng H, Beliavsky A, Tchigvintsev A, Brunzelle JS, Brown G, Flick R, Evdokimova E, Wawrzak Z, MAhadevan R, Anderson WF, Savchenko A, Yakunin AF
CSGID, Proteins
(Details)(Pubmed ID: 23229889)
PDB ID(s): 3ETF 3EFV
Times cited: 12
- Genome3D: a UK collaborative project to annotate genomic sequences with predicted 3D structures based on SCOP and CATH doMAins.
Lewis TE, Sillitoe I, Andreeva A, Blundell TL, Buchan DW, Chothia C, Cuff A, Dana JM, Filippis I, Gough J, Hunter S, Jones DT, Kelley LA, Kleywegt GJ, Minneci F, Mitchell A, Murzin AG, Ochoa-Montaño B, Rackham OJ, Smith J, Sternberg MJ, Velankar S, Yeats C, Orengo C
CSGID, Nucleic Acids Research
(Details)(Pubmed ID: 23203986)
Times cited: 28
- New functional families (FunFams) in CATH to improve the MApping of conserved functional sites to 3D structures.
Sillitoe I, Cuff AL, Dessailly BH, Dawson NL, Furnham N, Lee D, Lees JG, Lewis TE, Studer RA, Rentzsch R, Yeats C, Thornton JM, Orengo CA
CSGID, Nucleic Acids Research
(Details)(Pubmed ID: 23203873)
Times cited: 143
- Broad-substrate screen as a tool to identify substrates for bacterial Gcn5-related N-acetyltransferases with unknown substrate specificity.
Kuhn ML, MAjorek KA, Minor W, Anderson WF
CSGID, Protein Science
(Details)(Pubmed ID: 23184347)
Times cited: 29
- Measurement of rate constants for homodimer subunit exchange using double electron-electron resonance and paraMAgnetic relaxation enhancements.
Yang Y, Ramelot TA, Ni S, McCarrick RM, Kennedy MA
NESG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 23180051)
Times cited: 5
- ATPase active-site electrostatic interactions control the global conforMAtion of the 100 kDa SecA translocase.
Kim DM, Zheng H, Huang YJ, Montelione GT, Hunt JF
NESG, Journal of the American Chemical Society
(Details)(Pubmed ID: 23167435)
Times cited: 8
- A broad specificity nucleoside kinase from ThermoplasMA acidophilum.
Elkin SR, KuMAr A, Price CW, Columbus L
JCSG, Proteins
(Details)(Pubmed ID: 23161756)
PDB ID(s): 3BF5
Times cited: 5
- Solution NMR structure of the helicase associated doMAin BVU_0683(627-691) from Bacteroides vulgatus provides first structural coverage for protein doMAin family PF03457 and indicates doMAin binding to DNA.
Mills JL, Acton TB, Xiao R, Everett JK, Montelione GT, Szyperski T
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 23160728)
Times cited: 0
- Modeling, docking, and fitting of atomic structures to 3D MAps from cryo-electron microscopy.
Allen GS, Stokes DL
TEMIMPS, Methods in Molecular Biology
(Details)(Pubmed ID: 23132064)
Times cited: 3
- Molecular Mechanisms Deployed by Virally Encoded G Protein-Coupled Receptors in HuMAn Diseases.
Montaner S, Kufareva I, Abagyan R, Gutkind JS
CHSAM, Annual review of pharmacology and toxicology
(Details)(Pubmed ID: 23092247)
Times cited: 27
2012
- Structural mechanism of ER retrieval of MHC class I by cowpox.
McCoy WH, Wang X, YokoyaMA WM, Hansen TH, Fremont DH
CSGID, PLoS Biology
(Details)(Pubmed ID: 23209377)
PDB ID(s): 4HKJ
Times cited: 10
- Metamorphic protein IscU changes conforMAtion by cis-trans isomerizations of two peptidyl-prolyl peptide bonds.
Dai Z, Tonelli M, MArkley JL
MPP, Biochemistry
(Details)(Pubmed ID: 23110687)
PDB ID(s): 2L4X
Times cited: 16
- Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter.
MAncusso R, Gregorio GG, Liu Q, Wang DN
NYCOMPS, Nature
(Details)(Pubmed ID: 23086149)
PDB ID(s): 4F35
Times cited: 77
- Assessing the accuracy of template-based structure prediction metaservers by comparison with structural genomics structures.
Gront D, Grabowski M, ZimmerMAn MD, Raynor J, Tkaczuk KL, Minor W
MCSG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 23086054)
Times cited: 6
- Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway.
Collins C, Guilluy C, Welch C, O'Brien ET, Hahn K, Superfine R, Burridge K, TziMA E
CELLMAT, Current biology : CB
(Details)(Pubmed ID: 23084990)
Times cited: 71
- Tug-of-war in motor protein ensembles revealed with a programMAble DNA origami scaffold.
Derr ND, GoodMAn BS, JungMAnn R, Leschziner AE, Shih WM, Reck-Peterson SL
MPSbyNMR, Science
(Details)(Pubmed ID: 23065903)
Times cited: 187
- Structural basis of differential neutralization of DENV-1 genotypes by an antibody that recognizes a cryptic epitope.
Austin SK, Dowd KA, Shrestha B, Nelson CA, Edeling MA, Johnson S, Pierson TC, Diamond MS, Fremont DH
CSGID, PLos Pathogens
(Details)(Pubmed ID: 23055922)
PDB ID(s): 4FFY 4FFZ
Times cited: 67
- Subzero temperature chroMAtography for reduced back-exchange and improved dynamic range in amide hydrogen/deuterium exchange MAss spectrometry.
Venable JD, Okach L, Agarwalla S, Brock A
JCSG, Analytical Chemistry
(Details)(Pubmed ID: 23025328)
Times cited: 17
- Structure-based prediction of protein-protein interactions on a genome-wide scale.
Zhang QC, Petrey D, Deng L, Qiang L, Shi Y, Thu CA, Bisikirska B, Lefebvre C, Accili D, Hunter T, MAniatis T, Califano A, Honig B
NESG, Nature
(Details)(Pubmed ID: 23023127)
Times cited: 307
- Folate binding site of flavin-dependent thymidylate synthase.
Koehn EM, Perissinotti LL, Moghram S, Prabhakar A, Lesley SA, MAthews II, Kohen A
JCSG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 23019356)
PDB ID(s): 4GT9 4GTA 4GTB 4GTC 4GTD 4GTE 4GTF 4GTL
Times cited: 17
- Comparative genomic analysis of the DUF71/COG2102 family predicts roles in diphthamide biosynthesis and B12 salvage.
de Crécy-Lagard V, Forouhar F, Brochier-ArMAnet C, Tong L, Hunt JF
NESG, Biology direct
(Details)(Pubmed ID: 23013770)
Times cited: 12
- Structural basis of the junctional anchorage of the cerebral cavernous MAlforMAtions complex.
Gingras AR, Liu JJ, Ginsberg MH
CELLMAT, The Journal of cell biology
(Details)(Pubmed ID: 23007647)
PDB ID(s): 3U7D
Times cited: 30
- Structure of a Novel Winged-Helix Like DoMAin from HuMAn NFRKB Protein.
KuMAr A, Möcklinghoff S, Yumoto F, Jaroszewski L, Farr CL, Grzechnik A, Nguyen P, Weichenberger CX, Chiu HJ, Klock HE, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Conklin BR, Fletterick RJ, Wilson IA
JCSG+STEMCELL, PLoS ONE
(Details)(Pubmed ID: 22984442)
PDB ID(s): 3U21
Times cited: 2
- Cross-neutralization of influenza A viruses mediated by a single antibody loop.
Ekiert DC, Kashyap AK, Steel J, Rubrum A, Bhabha G, Khayat R, Lee JH, Dillon MA, O'Neil RE, Faynboym AM, Horowitz M, Horowitz L, Ward AB, Palese P, Webby R, Lerner RA, Bhatt RR, Wilson IA
JCSG, Nature
(Details)(Pubmed ID: 22982990)
PDB ID(s): 4FNK 4FNL 4FP8 4FQR
Times cited: 194
- Structure of hepatitis C virus envelope glycoprotein E2 antigenic site 412 to 423 in complex with antibody AP33.
Kong L, Giang E, NieusMA T, Robbins JB, Deller MC, Stanfield RL, Wilson IA, Law M
JCSG, Journal of Virology
(Details)(Pubmed ID: 22973046)
PDB ID(s): 4G6A
Times cited: 55
- Harvesting and cryo-cooling crystals of membrane proteins grown in lipidic mesophases for structure determination by MAcromolecular crystallography.
Li D, Boland C, Aragao D, Walsh K, Caffrey M
MPID, Journal of visualized experiments : JoVE
(Details)(Pubmed ID: 22971942)
Times cited: 11
- MApping spatial approxiMAtions between the amino terminus of secretin and each of the extracellular loops of its receptor using cysteine trapping.
Dong M, Xu X, Ball AM, MAkhoul JA, Lam PC, Pinon DI, Orry A, Sexton PM, Abagyan R, Miller LJ
CHSAM, FASEB Journal
(Details)(Pubmed ID: 22964305)
Times cited: 21
- LocTree2 predicts localization for all doMAins of life.
Goldberg T, Hamp T, Rost B
NYCOMPS, Bioinformatics
(Details)(Pubmed ID: 22962467)
Times cited: 50
- Crystal structure of the MArburg virus GP2 core doMAin in its postfusion conforMAtion.
Koellhoffer JF, MAlashkevich VN, Harrison JS, Toro R, Bhosle RC, Chandran K, Almo SC, Lai JR
NYSGRC, Biochemistry
(Details)(Pubmed ID: 22935026)
PDB ID(s): 4G2K
Times cited: 26
- Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion.
SaMAnta D, RaMAgopal UA, Rubinstein R, Vigdorovich V, Nathenson SG, Almo SC
IFN+NYSGRC, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 22927415)
PDB ID(s): 3R0N
Times cited: 19
- Characterization of transport proteins for aroMAtic compounds derived from lignin: benzoate derivative binding proteins
Michalska K, Chang C, MAck JC, Zerbs S, Joachimiak A, Collart FR.
MCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 22925578)
PDB ID(s): 4F06 4EYK 4EYG 4EY3 4EVS 4EVR 4EVQ
Times cited: 12
- Predicting HLA class I non-permissive amino acid residues substitutions.
Binkowski TA, MArino SR, Joachimiak A
MCSG, PLoS ONE
(Details)(Pubmed ID: 22905104)
Times cited: 11
- A fluorescence-detection size-exclusion chroMAtography-based thermostability assay for membrane protein precrystallization screening.
Hattori M, Hibbs RE, Gouaux E
NYCOMPS, Structure
(Details)(Pubmed ID: 22884106)
Times cited: 89
- Structure of a specialized acyl carrier protein essential for lipid a biosynthesis with very long-chain Fatty acids in open and closed conforMAtions.
Ramelot TA, Rossi P, Forouhar F, Lee HW, Yang Y, Ni S, Unser S, Lew S, SeetharaMAn J, Xiao R, Acton TB, Everett JK, Prestegard JH, Hunt JF, Montelione GT, Kennedy MA
NESG, Biochemistry
(Details)(Pubmed ID: 22876860)
Times cited: 6
- Computational design of catalytic dyads and oxyanion holes for ester hydrolysis.
Richter F, Blomberg R, Khare SD, Kiss G, Kuzin AP, Smith AJ, Gallaher J, Pianowski Z, Helgeson RC, Grjasnow A, Xiao R, SeetharaMAn J, Su M, Vorobiev S, Lew S, Forouhar F, Kornhaber GJ, Hunt JF, Montelione GT, Tong L, Houk KN, Hilvert D, Baker D
NESG, Journal of the American Chemical Society
(Details)(Pubmed ID: 22871159)
Times cited: 66
- Solution NMR and X-ray crystal structures of Pseudomonas syringae Pspto_3016 from protein doMAin family PF04237 (DUF419) adopt a "double wing" DNA binding motif.
FeldMAnn EA, SeetharaMAn J, Ramelot TA, Lew S, Zhao L, Hamilton K, Ciccosanti C, Xiao R, Acton TB, Everett JK, Tong L, Montelione GT, Kennedy MA
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 22865330)
Times cited: 3
- Structure of an MmyB-like regulator from C. aurantiacus, member of a new transcription factor family linked to antibiotic metabolism in actinomycetes.
Xu Q, van Wezel GP, Chiu HJ, Jaroszewski L, Klock HE, Knuth MW, Miller MD, Lesley SA, Godzik A, Elsliger MA, Deacon AM, Wilson IA
JCSG, PLoS ONE
(Details)(Pubmed ID: 22844465)
PDB ID(s): 3PXP
Times cited: 7
- Crystal structure of a catalytically active GG(D/E)EF diguanylate cyclase doMAin from MArinobacter aquaeolei with bound c-di-GMP product.
Vorobiev SM, Neely H, Yu B, SeetharaMAn J, Xiao R, Acton TB, Montelione GT, Hunt JF
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 22843345)
Times cited: 6
- Three structural representatives of the PF06855 protein doMAin family from Staphyloccocus aureus and Bacillus subtilis have SAM doMAin-like folds and different functions.
Swapna GV, Rossi P, Montelione AF, Benach J, Yu B, Abashidze M, SeetharaMAn J, Xiao R, Acton TB, Tong L, Montelione GT
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 22843344)
Times cited: 0
- Solution NMR Structure of Hypothetical Protein CV_2116 Encoded by a Viral Prophage Element in Chromobacterium violaceum.
Yang Y, Ramelot TA, Cort JR, Garcia M, Yee A, Arrowsmith CH, Kennedy MA
NESG, International journal of molecular sciences
(Details)(Pubmed ID: 22837698)
Times cited: 1
- Integrative structural modeling with sMAll angle X-ray scattering profiles.
SchneidMAn-Duhovny D, Kim SJ, Sali A
NYSGRC, BMC Structural Biology
(Details)(Pubmed ID: 22800408)
Times cited: 47
- Structural basis for allosteric regulation of GPCRs by sodium ions.
Liu W, Chun E, Thompson AA, Chubukov P, Xu F, Katritch V, Han GW, Roth CB, HeitMAn LH, IJzerMAn AP, Cherezov V, Stevens RC
GPCR, Science
(Details)(Pubmed ID: 22798613)
PDB ID(s): 4EIY
Times cited: 462
- Bacillus anthracis Inosine 5'-Monophosphate Dehydrogenase in Action: The First Bacterial Series of Structures of Phosphate Ion-, Substrate-, and Product-Bound Complexes.
MAkowska-Grzyska M, Kim Y, Wu R, Wilton R, Gollapalli DR, Wang XK, Zhang R, Jedrzejczak R, MAck JC, MAltseva N, Mulligan R, Binkowski TA, Gornicki P, Kuhn ML, Anderson WF, Hedstrom L, Joachimiak A
CSGID, Biochemistry
(Details)(Pubmed ID: 22788966)
PDB ID(s): 3USB 3TSB 3TSD
Times cited: 22
- Specialized Hsp70 chaperone (HscA) binds preferentially to the disordered form, whereas J-protein (HscB) binds preferentially to the structured form of the iron-sulfur cluster scaffold protein (IscU).
Kim JH, Tonelli M, Frederick RO, Chow DC, MArkley JL
MPP, Journal of Biological Chemistry
(Details)(Pubmed ID: 22782893)
PDB ID(s): 2L4X
Times cited: 28
- Structural insights into electron transfer in caa3-type cytochrome oxidase.
Lyons JA, Aragão D, Slattery O, Pisliakov AV, SouliMAne T, Caffrey M
MPID, Nature
(Details)(Pubmed ID: 22763450)
Times cited: 64
- The J-UNIO protocol for autoMAted protein structure determination by NMR in solution.
Serrano P, Pedrini B, Mohanty B, Geralt M, HerrMAnn T, Wüthrich K
JCSG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 22752932)
Times cited: 43
- The Structure of Vimentin Linker 1 and Rod 1B DoMAins Characterized by Site-directed Spin-labeling Electron ParaMAgnetic Resonance (SDSL-EPR) and X-ray Crystallography.
Aziz A, Hess JF, BudaMAgunta MS, Voss JC, Kuzin AP, Huang YJ, Xiao R, Montelione GT, Fitzgerald PG, Hunt JF
NESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 22740688)
Times cited: 29
- Three-Dimensional Structure and Determinants of Stability of the Iron-Sulfur Cluster Scaffold Protein IscU from Escherichia coli.
Hae Kim J, Tonelli M, Kim T, MArkley JL
MPP, Biochemistry
(Details)(Pubmed ID: 22734684)
PDB ID(s): 2L4X
Times cited: 22
- Structure and permeation mechanism of a MAmMAlian urea transporter.
Levin EJ, Cao Y, Enkavi G, Quick M, Pan Y, Tajkhorshid E, Zhou M
NYCOMPS, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 22733730)
PDB ID(s): 4EZC 4EZD
Times cited: 36
- Twelve transmembrane helices form the functional core of MAmMAlian MATE1 (multidrug and toxin extruder 1) protein.
Zhang X, He X, Baker J, TaMA F, Chang G, Wright SH
TransportPDB, Journal of Biological Chemistry
(Details)(Pubmed ID: 22722930)
Times cited: 23
- A conforMAtional switch controls cell wall-remodelling enzymes required for bacterial cell division.
Yang DC, Tan K, Joachimiak A, Bernhardt TG
MCSG, Molecular Microbiology
(Details)(Pubmed ID: 22715947)
PDB ID(s): 3NE8
Times cited: 45
- Structural and immunologic characterization of bovine, horse, and rabbit serum albumins.
MAjorek KA, Porebski PJ, Dayal A, ZimmerMAn MD, Jablonska K, Stewart AJ, Chruszcz M, Minor W
NYSGRC, Accounts of Chemical Research
(Details)(Pubmed ID: 22677715)
PDB ID(s): 3V03 3V08 3V09
Times cited: 272
- Accurate protein structure modeling using sparse NMR data and homologous structure inforMAtion.
Thompson JM, Sgourakis NG, Liu G, Rossi P, Tang Y, Mills JL, Szyperski T, Montelione GT, Baker D
NESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 22665781)
Times cited: 25
- A multi-faceted analysis of RutD reveals a novel family of α/β hydrolases.
Knapik AA, Petkowski JJ, Otwinowski Z, Cymborowski MT, Cooper DR, MAjorek KA, Chruszcz M, Krajewska WM, Minor W
NYSGRC, Proteins
(Details)(Pubmed ID: 22641504)
Times cited: 4
- Increasing sequence diversity with flexible backbone protein design: the complete redesign of a protein hydrophobic core.
Murphy GS, Mills JL, Miley MJ, MAchius M, Szyperski T, KuhlMAn B
NESG, Structure
(Details)(Pubmed ID: 22632833)
Times cited: 29
- Structures from anoMAlous diffraction of native biological MAcromolecules.
Liu Q, DahMAne T, Zhang Z, Assur Z, Brasch J, Shapiro L, MAncia F, Hendrickson WA
NYCOMPS, Science
(Details)(Pubmed ID: 22628655)
Times cited: 90
- Structural genomics plucks high-hanging membrane proteins.
KloppMAnn E, Punta M, Rost B
NYCOMPS, Current Opinion in Structural Biology
(Details)(Pubmed ID: 22622032)
Times cited: 20
- SALIGN: a web server for alignment of multiple protein sequences and structures.
Braberg H, Webb BM, Tjioe E, Pieper U, Sali A, MAdhusudhan MS
NYSGRC, Bioinformatics
(Details)(Pubmed ID: 22618536)
Times cited: 39
- Facile backbone structure determination of huMAn membrane proteins by NMR spectroscopy.
Klammt C, MAslennikov I, Bayrhuber M, EichMAnn C, Vajpai N, Chiu EJ, Blain KY, Esquivies L, Kwon JH, Balana B, Pieper U, Sali A, Slesinger PA, Kwiatkowski W, Riek R, Choe S
NYSGRC, Nature Methods
(Details)(Pubmed ID: 22609626)
Times cited: 54
- Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam doMAin family PF11267.
Aramini JM, Petrey D, Lee DY, Janjua H, Xiao R, Acton TB, Everett JK, Montelione GT
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 22592539)
Times cited: 2
- Docking and scoring with ICM: the benchMArking results and strategies for improvement.
Neves MA, Totrov M, Abagyan R
CHSAM+GPCR, Accounts of Chemical Research
(Details)(Pubmed ID: 22569591)
Times cited: 108
- Agonists for 13 trace amine-associated receptors provide insight into the molecular basis of odor selectivity.
Ferrero DM, Wacker D, Roque MA, Baldwin MW, Stevens RC, Liberles SD
GPCR, ACS Chemical Biology
(Details)(Pubmed ID: 22545963)
Times cited: 43
- Atomic structure of the nuclear pore complex targeting doMAin of a Nup116 homologue from the yeast, Candida glabrata.
SampathkuMAr P, Kim SJ, MAnglicmot D, Bain KT, Gilmore J, Gheyi T, Phillips J, Pieper U, Fernandez-MArtinez J, Franke JD, MAtsui T, Tsuruta H, Atwell S, Thompson DA, Emtage JS, WasserMAn SR, Rout MP, Sali A, Sauder JM, Almo SC, Burley SK
NPCXstals+NYSGRC, Proteins
(Details)(Pubmed ID: 22544723)
PDB ID(s): 3NF5
Times cited: 4
- Crystal structure of tandem ACT doMAin-containing protein ACTP from Galdieria sulphuraria.
Bitto E, Kim do J, BingMAn CA, Kim HJ, Han BW, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 22528523)
PDB ID(s): 2NYI
Times cited: 0
- The Protein Structure Initiative Structural Biology Knowledgebase Technology Portal: a structural biology web resource.
Gifford LK, Carter LG, Gabanyi MJ, BerMAn HM, Adams PD
PSISBKB, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 22527514)
Times cited: 13
- Structure and activity of the cold-active and anion-activated carboxyl esterase OLEI01171 from the oil-degrading MArine bacterium Oleispira antarctica.
LeMAk S, Tchigvintsev A, Petit P, Flick R, Singer AU, Brown G, Evdokimova E, Egorova O, Gonzalez CF, Chernikova TN, Yakimov MM, Kube M, Reinhardt R, Golyshin PN, Savchenko A, Yakunin AF
MCSG, Biochemical Journal
(Details)(Pubmed ID: 22519667)
PDB ID(s): 3S8Y
Times cited: 14
- Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis.
Nocek B, Tikhonov A, Babnigg G, Gu M, Zhou M, MAkarova KS, Vondenhoff G, Aerschot AV, Kwon K, Anderson WF, Severinov K, Joachimiak A
CSGID, Journal of Molecular Biology
(Details)(Pubmed ID: 22516613)
PDB ID(s): 3GJZ 3SR3 3T5M 3TYX 3U1B
Times cited: 11
- Structural analysis of a 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with an N-terminal chorisMAte mutase-like regulatory doMAin.
Light SH, Halavaty AS, Minasov G, Shuvalova L, Anderson WF
CSGID, Protein Science
(Details)(Pubmed ID: 22505283)
PDB ID(s): 3NVT 3TFC
Times cited: 13
- Application of DEN refinement and autoMAted model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum.
Brunger AT, Das D, Deacon AM, Grant J, Terwilliger TC, Read RJ, Adams PD, Levitt M, Schröder GF
JCSG, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 22505259)
PDB ID(s): 3TX8
Times cited: 17
- Unusual arginine forMAtions in protein function and assembly: rings, strings, and stacks.
Neves MA, Yeager M, Abagyan R
CHSAM+GPCR, Journal of Physical Chemistry B
(Details)(Pubmed ID: 22497303)
Times cited: 35
- Solution NMR structure, backbone dynamics, and heme-binding properties of a novel cytochrome c MAturation protein CcmE from Desulfovibrio vulgaris.
Aramini JM, Hamilton K, Rossi P, Ertekin A, Lee HW, LeMAk A, Wang H, Xiao R, Acton TB, Everett JK, Montelione GT
NESG, Biochemistry
(Details)(Pubmed ID: 22497251)
Times cited: 7
- Characterization of member of DUF1888 protein family, self-cleaving and self-assembling endopeptidase.
Osipiuk J, Mulligan R, Bargassa M, Hamilton JE, Cunningham MA, Joachimiak A
MCSG, Journal of Biological Chemistry
(Details)(Pubmed ID: 22493430)
PDB ID(s): 3N55 3NJI 3NJH 3NJG 3NJF 3NJJ 3NJK 3NJL 3NJM 3NJN
Times cited: 4
- An asymmetry-to-symmetry switch in signal transmission by the histidine kinase receptor for TMAO.
Moore JO, Hendrickson WA
NYCOMPS, Structure
(Details)(Pubmed ID: 22483119)
Times cited: 33
- MAgic-angle-spinning NMR of the drug resistant S31N M2 proton transporter from influenza A.
Andreas LB, Eddy MT, Chou JJ, Griffin RG
MPSbyNMR, Journal of the American Chemical Society
(Details)(Pubmed ID: 22480220)
Times cited: 38
- Highlights from recently determined structures of membrane proteins: a focus on channels and transporters.
Sciara G, MAncia F
NYCOMPS, Current Opinion in Structural Biology
(Details)(Pubmed ID: 22472602)
Times cited: 9
- Molecular basis for binding and subtype selectivity of 1,4-benzodiazepine antagonist ligands of the cholecystokinin receptor.
Cawston EE, Lam PC, HarikuMAr KG, Dong M, Ball AM, Augustine ML, Akgün E, Portoghese PS, Orry A, Abagyan R, Sexton PM, Miller LJ
CHSAM+GPCR, Journal of Biological Chemistry
(Details)(Pubmed ID: 22467877)
Times cited: 11
- The Structure of Mlc Titration Factor A (MtfA/YeeI) Reveals a Prototypical Zinc Metallopeptidase Related to Anthrax Lethal Factor.
Xu Q, Göhler AK, Kosfeld A, Carlton D, Chiu HJ, Klock HE, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Jahreis K, Wilson IA
JCSG, Journal of Bacteriology
(Details)(Pubmed ID: 22467785)
PDB ID(s): 3DL1 3KHI
Times cited: 6
- Transient structure and dynamics in the disordered c-Myc transactivation doMAin affect Bin1 binding.
Andresen C, Helander S, LeMAk A, Farès C, Csizmok V, Carlsson J, Penn LZ, ForMAn-Kay JD, Arrowsmith CH, Lundström P, Sunnerhagen M
NESG, Nucleic Acids Research
(Details)(Pubmed ID: 22457068)
Times cited: 47
- Structure of the huMAn κ-opioid receptor in complex with JDTic
Wu H, Wacker D, Mileni M, Katritch V, Han GW, Vardy E, Liu W, Thompson AA, Huang XP, Carroll FI, MAscarella SW, Westkaemper RB, Mosier PD, Roth BL, Cherezov V, Stevens RC
GPCR, Nature
(Details)(Pubmed ID: 22437504)
PDB ID(s): 4DJH
Times cited: 523
- HuMAn cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region.
Ertekin A, Aramini JM, Rossi P, Leonard PG, Janjua H, Xiao R, MAglaqui M, Lee HW, Prestegard JH, Montelione GT
NESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 22427660)
Times cited: 3
- Solution NMR structure of the ribosoMAl protein RP-L35Ae from Pyrococcus furiosus.
Snyder DA, Aramini JM, Yu B, Huang YJ, Xiao R, Cort JR, Shastry R, MA LC, Liu J, Rost B, Acton TB, Kennedy MA, Montelione GT
NESG, Proteins
(Details)(Pubmed ID: 22422653)
Times cited: 2
- Functional and structural characterization of a thermostable acetyl esterase from Thermotoga MAritiMA.
Levisson M, Han GW, Deller MC, Xu Q, Biely P, Hendriks S, Ten Eyck LF, Flensburg C, Roversi P, Miller MD, McMullan D, von Delft F, Kreusch A, Deacon AM, van der Oost J, Lesley SA, Elsliger MA, Kengen SW, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 22411095)
PDB ID(s): 1VLQ 3M81 3M82 3M83
Times cited: 23
- Functional and structural analysis of the siderophore synthetase AsbB through reconstitution of the petrobactin biosynthetic pathway from Bacillus anthracis.
Nusca TD, Kim Y, MAltseva N, Lee JY, Eschenfeldt W, Stols L, Schofield MM, Scaglione JB, Dixon SD, Oves-Costales D, Challis GL, Hanna PC, Pfleger BF, Joachimiak A, SherMAn DH
MCSG, Journal of Biological Chemistry
(Details)(Pubmed ID: 22408253)
PDB ID(s): 3TO3
Times cited: 15
- Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
Lukk T, Sakai A, KalyanaraMAn C, Brown SD, Imker HJ, Song L, Fedorov AA, Fedorov EV, Toro R, Hillerich B, Seidel R, Patskovsky Y, Vetting MW, Nair SK, Babbitt PC, Almo SC, Gerlt JA, Jacobson MP
NYSGRC, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 22392983)
Times cited: 41
- Segmental isotope labeling of proteins for NMR structural study using a protein S tag for higher expression and solubility.
Kobayashi H, Swapna GV, Wu KP, Afinogenova Y, Conover K, MAo B, Montelione GT, Inouye M
NESG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 22389115)
Times cited: 13
- Crystal structure of a putative isochorisMAtase hydrolase from Oleispira antarctica.
Goral AM, Tkaczuk KL, Chruszcz M, Kagan O, Savchenko A, Minor W
MCSG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 22350524)
PDB ID(s): 3LQY
Times cited: 10
- Crystal structure of a lipid G protein-coupled receptor.
Hanson MA, Roth CB, Jo E, Griffith MT, Scott FL, Reinhart G, Desale H, Clemons B, Cahalan SM, Schuerer SC, Sanna MG, Han GW, Kuhn P, Rosen H, Stevens RC
GPCR, Science
(Details)(Pubmed ID: 22344443)
PDB ID(s): 3V2W 3V3Y
Times cited: 407
- A systeMAtic approach to increase the efficiency of membrane protein production in cell-free expression systems
Haberstock S, Roos C, Hoevels Y, Dötsch V, Schnapp G, Pautsch A, Bernhard F.
MPSbyNMR, Protein Expression and Purification
(Details)(Pubmed ID: 22342679)
Times cited: 36
- Blind testing of routine, fully autoMAted determination of protein structures from NMR data.
Rosato A, Aramini JM, Arrowsmith C, Bagaria A, Baker D, Cavalli A, Doreleijers JF, Eletsky A, Giachetti A, Guerry P, GutMAnas A, Güntert P, He Y, HerrMAnn T, Huang YJ, Jaravine V, Jonker HR, Kennedy MA, Lange OF, Liu G, MAlliavin TE, MAni R, MAo B, Montelione GT, Nilges M, Rossi P, van der Schot G, Schwalbe H, Szyperski TA, Vendruscolo M, Vernon R, Vranken WF, de Vries S, Vuister GW, Wu B, Yang Y, Bonvin AM
NESG, Structure
(Details)(Pubmed ID: 22325772)
Times cited: 54
- AutoMAted protein structure modeling with SWISS-MODEL Workspace and the Protein Model Portal.
Bordoli L, Schwede T
PSISBKB, Methods in Molecular Biology
(Details)(Pubmed ID: 22323219)
Times cited: 66
- Overexpressing huMAn membrane proteins in stably transfected and clonal huMAn embryonic kidney 293S cells.
Chaudhary S, Pak JE, Gruswitz F, SharMA V, Stroud RM
CSMP, Nature Protocols
(Details)(Pubmed ID: 22322218)
Times cited: 29
- Interaction of j-protein co-chaperone jac1 with fe-s scaffold isu is indispensable in vivo and conserved in evolution.
Ciesielski SJ, Schilke BA, Osipiuk J, Bigelow L, Mulligan R, MAjewska J, Joachimiak A, MArszalek J, Craig EA, Dutkiewicz R
MCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 22306468)
PDB ID(s): 3UO2 3UO3
Times cited: 28
- Enhancement of crystallization with nucleotide ligands identified by dye-ligand affinity chroMAtography.
Kim H, Webster C, Roberts JK, Kositsawat J, Hung LW, Terwilliger TC, Kim CY
MTBI, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 22286688)
Times cited: 4
- Lipidic phase membrane protein serial femtosecond crystallography.
Johansson LC, Arnlund D, White TA, Katona G, Deponte DP, Weierstall U, Doak RB, ShoeMAn RL, Lomb L, MAlmerberg E, Davidsson J, Nass K, Liang M, Andreasson J, Aquila A, Bajt S, Barthelmess M, Barty A, Bogan MJ, Bostedt C, Bozek JD, CaleMAn C, Coffee R, Coppola N, Ekeberg T, Epp SW, Erk B, Fleckenstein H, Foucar L, GraafsMA H, Gumprecht L, Hajdu J, Hampton CY, HartMAnn R, HartMAnn A, Hauser G, HirseMAnn H, Holl P, Hunter MS, Kassemeyer S, Kimmel N, Kirian RA, MAia FR, MArchesini S, MArtin AV, Reich C, Rolles D, Rudek B, Rudenko A, Schlichting I, Schulz J, Seibert MM, Sierra RG, Soltau H, Starodub D, Stellato F, Stern S, Strüder L, Timneanu N, Ullrich J, Wahlgren WY, Wang X, Weidenspointner G, Wunderer C, Fromme P, ChapMAn HN, Spence JC, Neutze R
MPID, Nature Methods
(Details)(Pubmed ID: 22286383)
Times cited: 101
- Combinatorial triple-selective labeling as a tool to assist membrane protein backbone resonance assignment.
Löhr F, Reckel S, Karbyshev M, Connolly PJ, Abdul-MAnan N, Bernhard F, Moore JM, Dötsch V
MPSbyNMR, Journal of Biomolecular NMR
(Details)(Pubmed ID: 22252484)
Times cited: 16
- Real-space processing of helical filaments in SPARX.
BehrMAnn E, Tao G, Stokes DL, EgelMAn EH, Raunser S, Penczek PA
TEMIMPS, Journal of Structural Biology
(Details)(Pubmed ID: 22248449)
Times cited: 20
- Structures of LeuT in bicelles define conforMAtion and substrate binding in a membrane-like context.
Wang H, Elferich J, Gouaux E
NYCOMPS, Nature Structural & Molecular Biology
(Details)(Pubmed ID: 22245965)
PDB ID(s): 3USG 3USI 3USJ 3USK 3USL 3USM 3USO 3USP
Times cited: 72
- Solution NMR structures reveal unique homodimer forMAtion by a winged helix-turn-helix motif and provide first structures for protein doMAin family PF10771.
Eletsky A, Petrey D, Zhang QC, Lee HW, Acton TB, Xiao R, Everett JK, Prestegard JH, Honig B, Montelione GT, Szyperski T
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 22223187)
Times cited: 2
- Bicelles at low concentrations
Lu Z, Van Horn WD, Chen J, MAthew S, Zent R, Sanders CR
MPSbyNMR, Molecular Pharmacology
(Details)(Pubmed ID: 22221179)
Times cited: 25
- Structure of the pilus assembly protein TadZ from Eubacterium rectale: implications for polar localization.
Xu Q, Christen B, Chiu HJ, Jaroszewski L, Klock HE, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Figurski DH, Shapiro L, Wilson IA
JCSG, Molecular Microbiology
(Details)(Pubmed ID: 22211578)
PDB ID(s): 3FKQ
Times cited: 12
- Disordered form of the scaffold protein IscU is the substrate for iron-sulfur cluster assembly on cysteine desulfurase.
Kim JH, Tonelli M, MArkley JL
MPP, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 22203963)
PDB ID(s): 2L4X
Times cited: 37
- Solution NMR structures reveal a distinct architecture and provide first structures for protein doMAin family PF04536.
Eletsky A, Acton TB, Xiao R, Everett JK, Montelione GT, Szyperski T
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 22198206)
Times cited: 7
- Structural analysis of HopPMAL reveals the presence of a second adaptor doMAin common to the HopAB family of Pseudomonas syringae type III effectors.
Singer AU, Wu B, Yee A, Houliston S, Xu X, Cui H, Skarina T, Garcia M, Semesi A, Arrowsmith CH, Savchenko A
NESG, Biochemistry
(Details)(Pubmed ID: 22191472)
PDB ID(s): 3SVI 3TJY 2LF3 2LF6
Times cited: 5
- Crystal structure of the Japanese encephalitis virus envelope protein.
Luca VC, AbiMAnsour J, Nelson CA, Fremont DH
CSGID, Journal of Virology
(Details)(Pubmed ID: 22156523)
PDB ID(s): 3P54
Times cited: 98
- Gene3D: a doMAin-based resource for comparative genomics, functional annotation and protein network analysis.
Lees J, Yeats C, Perkins J, Sillitoe I, Rentzsch R, Dessailly BH, Orengo C
CSGID, Nucleic Acids Research
(Details)(Pubmed ID: 22139938)
Times cited: 43
- Bifidobacterium longum subsp. infantis ATCC 15697 α-fucosidases are active on fucosylated huMAn milk oligosaccharides.
Sela DA, Garrido D, Lerno L, Wu S, Tan K, Eom HJ, Joachimiak A, Lebrilla CB, Mills DA
MCSG, Applied and environmental microbiology
(Details)(Pubmed ID: 22138995)
PDB ID(s): 3MO4
Times cited: 78
- The structure and enzyMAtic properties of a novel RNase II family enzyme from Deinococcus radiodurans.
Schmier BJ, SeetharaMAn J, Deutscher MP, Hunt JF, MAlhotra A
NESG, Journal of Molecular Biology
(Details)(Pubmed ID: 22133431)
Times cited: 3
- Solution NMR structure of BT_0084, a conjugative transposon lipoprotein from Bacteroides thetaiotamicron.
Ramelot TA, Yang Y, Xiao R, Acton TB, Everett JK, Montelione GT, Kennedy MA
NESG, Proteins
(Details)(Pubmed ID: 22116783)
Times cited: 1
- Solution NMR structure of Asl3597 from Nostoc sp. PCC7120, the first structure from protein doMAin family PF12095, reveals a novel fold.
FeldMAnn EA, Ramelot TA, Yang Y, Xiao R, Acton TB, Everett JK, Montelione GT, Kennedy MA
NESG, Proteins
(Details)(Pubmed ID: 22113821)
Times cited: 1
- Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound A2A adenosine receptor
Deflorian F, KuMAr TS, Phan K, Gao ZG, Xu F, Wu H, Katritch V, Stevens RC, Jacobson KA
GPCR, Journal of Medicinal Chemistry
(Details)(Pubmed ID: 22104008)
Times cited: 28
- InterPro in 2011: new developments in the family and doMAin prediction database.
Hunter S, Jones P, Mitchell A, Apweiler R, Attwood TK, BateMAn A, Bernard T, Binns D, Bork P, Burge S, de Castro E, Coggill P, Corbett M, Das U, Daugherty L, Duquenne L, Finn RD, Fraser M, Gough J, Haft D, Hulo N, Kahn D, Kelly E, Letunic I, Lonsdale D, Lopez R, MAdera M, MAslen J, McAnulla C, McDowall J, McMenamin C, Mi H, Mutowo-Muellenet P, Mulder N, Natale D, Orengo C, Pesseat S, Punta M, Quinn AF, Rivoire C, Sangrador-Vegas A, Selengut JD, Sigrist CJ, Scheremetjew M, Tate J, ThimMAjanarthanan M, ThoMAs PD, Wu CH, Yeats C, Yong SY
CSGID, Nucleic Acids Research
(Details)(Pubmed ID: 22096229)
Times cited: 691
- Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer.
Der BS, MAchius M, Miley MJ, Mills JL, Szyperski T, KuhlMAn B
NESG, Journal of the American Chemical Society
(Details)(Pubmed ID: 22092237)
Times cited: 55
- Pocketome: an encyclopedia of sMAll-molecule binding sites in 4D.
Kufareva I, Ilatovskiy AV, Abagyan R
CHSAM+GPCR, Nucleic Acids Research
(Details)(Pubmed ID: 22080553)
Times cited: 64
- Crystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB doMAins in huMAn AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification.
Pastore C, Topalidou I, Forouhar F, Yan AC, Levy M, Hunt JF
NESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 22065580)
PDB ID(s): 3THP 3THT
Times cited: 34
- Diversity and modularity of G protein-coupled receptor structures.
Katritch V, Cherezov V, Stevens RC
GPCR, Trends in pharmacological sciences
(Details)(Pubmed ID: 22032986)
Times cited: 250
- FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies.
Furnham N, Sillitoe I, Holliday GL, Cuff AL, RahMAn SA, Laskowski RA, Orengo CA, Thornton JM
MCSG, Nucleic Acids Research
(Details)(Pubmed ID: 22006843)
Times cited: 22
- Tools for coproducing multiple proteins in MAmMAlian cells.
Assur Z, Hendrickson WA, MAncia F
NYCOMPS, Methods in Molecular Biology
(Details)(Pubmed ID: 21987254)
Times cited: 2
- Structural characterization of huMAn Uch37.
Burgie SE, BingMAn CA, Soni AB, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 21953935)
PDB ID(s): 3IHR
Times cited: 19
- HuMAn retinoblastoMA binding protein 9, a serine hydrolase implicated in pancreatic cancers.
Vorobiev SM, Huang YJ, SeetharaMAn J, Xiao R, Acton TB, Montelione GT, Tong L
NESG, Protein and peptide letters
(Details)(Pubmed ID: 21933118)
Times cited: 3
- Yeast cytochrome c oxidase: a model system to study mitochondrial forms of the haem-copper oxidase superfamily.
MAréchal A, Meunier B, Lee D, Orengo C, Rich PR
MCSG, Biochimica et biophysica acta
(Details)(Pubmed ID: 21925484)
Times cited: 29
- Δ1-pyrroline-5-carboxylate reductase as a new target for therapeutics: inhibition of the enzyme from Streptococcus pyogenes and effects in vivo.
Forlani G, Petrollino D, Fusetti M, RoMAnini L, Nocek B, Joachimiak A, Berlicki L, Kafarski P
MCSG, Amino Acids
(Details)(Pubmed ID: 21744012)
Times cited: 11
2011
- Large-scale experimental studies show unexpected amino acid effects on protein expression and solubility in vivo in E. coli.
Price WN, HandelMAn SK, Everett JK, Tong SN, Bracic A, Luff JD, Naumov V, Acton T, MAnor P, Xiao R, Rost B, Montelione GT, Hunt JF
NESG, Microbial informatics and experimentation
(Details)(Pubmed ID: 22587847)
Times cited: 8
- The FGGY Carbohydrate Kinase Family: Insights into the Evolution of Functional Specificities.
Zhang Y, Zagnitko O, Rodionova I, OsterMAn A, Godzik A
JCSG, PLoS Computational Biology
(Details)(Pubmed ID: 22215998)
Times cited: 21
- A sMAll molecule discrimination MAp of the antibiotic resistance kinome.
Shakya T, Stogios PJ, Waglechner N, Evdokimova E, Ejim L, Blanchard JE, McArthur AG, Savchenko A, Wright GD
CSGID, Chemistry & Biology
(Details)(Pubmed ID: 22195561)
PDB ID(s): 4DE4 4DFB 4DFU
Times cited: 40
- Structural conservation of the myoviridae phage tail sheath protein fold.
Aksyuk AA, Kurochkina LP, Fokine A, Forouhar F, Mesyanzhinov VV, Tong L, RossMAnn MG
NESG, Structure
(Details)(Pubmed ID: 22153511)
Times cited: 25
- The 1.7 Å resolution structure of At2g44920, a pentapeptide-repeat protein in the thylakoid lumen of Arabidopsis thaliana.
Ni S, McGookey ME, Tinch SL, Jones AN, JayaraMAn S, Tong L, Kennedy MA
NESG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 22139148)
Times cited: 4
- A large conforMAtional change in the putative ATP pyrophosphatase PF0828 induced by ATP binding.
Forouhar F, Saadat N, Hussain M, SeetharaMAn J, Lee I, Janjua H, Xiao R, Shastry R, Acton TB, Montelione GT, Tong L
NESG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 22102225)
Times cited: 3
- Structural investigation of riMAntadine inhibition of the AM2-BM2 chimera channel of influenza viruses
Pielak RM, Oxenoid K, Chou JJ.
MPSbyNMR, Structure
(Details)(Pubmed ID: 22078564)
PDB ID(s): 2LJC
Times cited: 46
- Disorder-to-order transition underlies the structural basis for the assembly of a transcriptionally active PGC-1α/ERRγ complex.
Devarakonda S, Gupta K, Chalmers MJ, Hunt JF, Griffin PR, Van Duyne GD, SpiegelMAn BM
NESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 22049338)
Times cited: 35
- Crystal structure of the ligand binding doMAin of netrin G2.
Brasch J, Harrison OJ, Ahlsen G, Liu Q, Shapiro L
NYCOMPS, Journal of Molecular Biology
(Details)(Pubmed ID: 22041449)
PDB ID(s): 3TBD
Times cited: 15
- Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction.
Kryshtafovych A, Moult J, Bartual SG, Bazan JF, BerMAn H, Casteel DE, Christodoulou E, Everett JK, HausMAnn J, Heidebrecht T, Hills T, Hui R, Hunt JF, SeetharaMAn J, Joachimiak A, Kennedy MA, Kim C, Lingel A, Michalska K, Montelione GT, Otero JM, Perrakis A, Pizarro JC, van Raaij MJ, Ramelot TA, Rousseau F, Tong L, Wernimont AK, Young J, Schwede T
MCSG, Proteins
(Details)(Pubmed ID: 22020785)
Times cited: 14
- Crystal structure-based virtual screening for fragment-like ligands of the huMAn histamine H(1) receptor
de Graaf C, Kooistra AJ, Vischer HF, Katritch V, Kuijer M, Shiroishi M, Iwata S, ShiMAmura T, Stevens RC, de Esch IJ, Leurs R
GPCR, Journal of Medicinal Chemistry
(Details)(Pubmed ID: 22007643)
Times cited: 140
- The Enzyme Function Initiative.
Gerlt JA, Allen KN, Almo SC, Armstrong RN, Babbitt PC, Cronan JE, Dunaway-MAriano D, Imker HJ, Jacobson MP, Minor W, Poulter CD, Raushel FM, Sali A, Shoichet BK, Sweedler JV
EFI, Biochemistry
(Details)(Pubmed ID: 21999478)
Times cited: 92
- Change in allosteric network affects binding affinities of PDZ doMAins: analysis through perturbation response scanning.
Gerek ZN, Ozkan SB
MPID, PLoS Computational Biology
(Details)(Pubmed ID: 21998559)
Times cited: 69
- Structural characterization of Hsp12, the heat shock protein from Saccharomyces cerevisiae, in aqueous solution where it is intrinsically disordered and in detergent micelles where it is locally α-helical.
Singarapu KK, Tonelli M, Chow DC, Frederick RO, Westler WM, MArkley JL
CESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 21998307)
PDB ID(s): 2LJL
Times cited: 19
- Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Chang A, Singh S, Helmich KE, Goff RD, BingMAn CA, Thorson JS, Phillips GN
CESG+NatPro, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 21987796)
PDB ID(s): 3OTG 3OTH 3OTI 3RSC
Times cited: 25
- The transition from closed to open conforMAtion of TreponeMA pallidum outer membrane-associated lipoprotein TP0453 involves membrane sensing and integration by two amphipathic helices.
Luthra A, Zhu G, Desrosiers DC, Eggers CH, Mulay V, Anand A, McArthur FA, RoMAno FB, CaiMAno MJ, Heuck AP, MAlkowski MG, Radolf JD
MPSBC+NESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 21965687)
Times cited: 19
- Structure of Apo- and Monometalated Forms of NDM-1-A Highly Potent Carbapenem-Hydrolyzing Metallo-β-LactaMAse
Kim Y, Tesar C, Mire J, Jedrzejczak R, Binkowski A, Babnigg G, Sacchettini J, Joachimiak A.
MCSG+MTBI, PLoS ONE
(Details)(Pubmed ID: 21931780)
PDB ID(s): 3RKJ 3RKK 3SBL 3SFP
Times cited: 47
- Efficient expression screening of huMAn membrane proteins in transiently transfected HuMAn Embryonic Kidney 293S cells.
Chaudhary S, Pak JE, Pedersen BP, Bang LJ, Zhang LB, Ngaw SM, Green RG, SharMA V, Stroud RM
CSMP, Methods
(Details)(Pubmed ID: 21925269)
Times cited: 15
- Accessing protein conforMAtional ensembles using room-temperature X-ray crystallography.
Fraser JS, van den Bedem H, Samelson AJ, Lang PT, Holton JM, Echols N, Alber T
JCSG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 21918110)
Times cited: 224
- Structural and Immunologic Characterization of Ara h 1, a MAjor Peanut Allergen.
Chruszcz M, MAleki SJ, MAjorek KA, DeMAs M, Bublin M, Solberg R, Hurlburt BK, Ruan S, MAttisohn CP, Breiteneder H, Minor W
NYSGRC, Journal of Biological Chemistry
(Details)(Pubmed ID: 21917921)
Times cited: 50
- Crystal structure of Arabidopsis thaliana 12-oxophytodienoate reductase isoform 3 in complex with 8-iso prostaglandin A(1).
Han BW, MAlone TE, Kim do J, BingMAn CA, Kim HJ, Fox BG, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 21915915)
PDB ID(s): 2G5W
Times cited: 2
- High-throughput protein purification and quality assessment for crystallization.
Kim Y, Babnigg G, Jedrzejczak R, Eschenfeldt WH, Li H, MAltseva N, Hatzos-Skintges C, Gu M, MAkowska-Grzyska M, Wu R, An H, Chhor G, Joachimiak A
CSGID+MCSG, Methods
(Details)(Pubmed ID: 21907284)
Times cited: 70
- Solution NMR structure of Dsy0195 homodimer from Desulfitobacterium hafniense: first structure representative of the YabP doMAin family of proteins involved in spore coat assembly.
Yang Y, Ramelot TA, Cort JR, Wang H, Ciccosanti C, Jiang M, Janjua H, Acton TB, Xiao R, Everett JK, Montelione GT, Kennedy MA
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 21904870)
Times cited: 3
- Amino acid determinants of substrate selectivity in the TrypanosoMA brucei sphingolipid synthase family.
Goren MA, Fox BG, Bangs JD
TMPC, Biochemistry
(Details)(Pubmed ID: 21899277)
Times cited: 3
- Trapping sMAll caffeine in a large GPCR pocket.
Xu F, Stevens RC
GPCR, Structure
(Details)(Pubmed ID: 21893281)
Times cited: 3
- Ligand-dependent perturbation of the conforMAtional ensemble for the GPCR β2 adrenergic receptor revealed by HDX.
West GM, Chien EY, Katritch V, Gatchalian J, Chalmers MJ, Stevens RC, Griffin PR
GPCR, Structure
(Details)(Pubmed ID: 21889352)
Times cited: 84
- Oligomeric State of the Oxalate Transporter, OxlT.
Kang DC, VenkataraMAn PA, Dumont ME, MAloney PC
MPSBC, Biochemistry
(Details)(Pubmed ID: 21866906)
Times cited: 6
- Orphan MAcrodoMAin protein (huMAn C6orf130) is an O-acyl-ADP-ribose deacylase: solution structure and catalytic properties.
Peterson FC, Chen D, Lytle BL, Rossi MN, Ahel I, Denu JM, VolkMAn BF
CESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 21849506)
PDB ID(s): 2LGR 2L8R
Times cited: 44
- Simple screening method for improving membrane protein thermostability.
MAncusso R, Karpowich NK, Czyzewski BK, Wang DN
NYCOMPS, Methods
(Details)(Pubmed ID: 21840396)
Times cited: 21
- Novel C-terminal Motif within Sec7 DoMAin of Guanine Nucleotide Exchange Factors Regulates ADP-ribosylation Factor (ARF) Binding and Activation.
Lowery J, Szul T, SeetharaMAn J, Jian X, Su M, Forouhar F, Xiao R, Acton TB, Montelione GT, Lin H, Wright JW, Lee E, Holloway ZG, Randazzo PA, Tong L, Sztul E
NESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 21828055)
Times cited: 8
- A gene optimization strategy that enhances production of fully functional P-glycoprotein in Pichia pastoris.
Bai J, Swartz DJ, Protasevich II, Brouillette CG, Harrell PM, Hildebrandt E, Gasser B, MAttanovich D, Ward A, Chang G, Urbatsch IL
TransportPDB, PLoS ONE
(Details)(Pubmed ID: 21826197)
Times cited: 49
- Fast fluorescence techniques for crystallography beamlines.
Stepanov S, Hilgart M, Yoder DW, MAkarov O, Becker M, Sanishvili R, Ogata CM, Venugopalan N, Aragão D, Caffrey M, Smith JL, Fischetti RF
MPID, Journal of Applied Crystallography
(Details)(Pubmed ID: 21808424)
Times cited: 12
- Structural basis for the sequence-specific recognition of huMAn ISG15 by the NS1 protein of influenza B virus.
Guan R, MA LC, Leonard PG, Amer BR, Sridharan H, Zhao C, Krug RM, Montelione GT
NESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 21808041)
Times cited: 29
- High throughput platforms for structural genomics of integral membrane proteins.
MAncia F, Love J
NYCOMPS, Current Opinion in Structural Biology
(Details)(Pubmed ID: 21807498)
Times cited: 16
- Structural Analysis of Papain-Like NlpC/P60 Superfamily Enzymes with a Circularly Permuted Topology Reveals Potential Lipid Binding Sites.
Xu Q, Rawlings ND, Chiu HJ, Jaroszewski L, Klock HE, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, PLoS ONE
(Details)(Pubmed ID: 21799766)
Times cited: 12
- Structural and sequence analysis of imelysin-like proteins implicated in bacterial iron uptake.
Xu Q, Rawlings ND, Farr CL, Chiu HJ, Grant JC, Jaroszewski L, Klock HE, Knuth MW, Miller MD, Weekes D, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, PLoS ONE
(Details)(Pubmed ID: 21799754)
Times cited: 10
- Structure of 2-oxo-3-deoxygalactonate kinase from Klebsiella pneumoniae.
Michalska K, Cuff ME, Tesar C, FeldMAnn B, Joachimiak A
MCSG, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 21795809)
PDB ID(s): 3R1X
Times cited: 3
- Solution NMR structure of MED25(391-543) comprising the activator-interacting doMAin (ACID) of huMAn mediator subunit 25.
Eletsky A, Ruyechan WT, Xiao R, Acton TB, Montelione GT, Szyperski T
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 21785987)
Times cited: 9
- X-ray crystallography: Assessment and validation of protein-sMAll molecule complexes for drug discovery.
Cooper DR, Porebski PJ, Chruszcz M, Minor W
CSGID+MCSG+NYSGRC, Expert Opin Drug Discov
(Details)(Pubmed ID: 21779303)
Times cited: 30
- Crystal structure of the β2 adrenergic receptor-Gs protein complex.
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, MAthiesen JM, Shah ST, Lyons JA, Caffrey M, GellMAn SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK, Kobilka BK
MPID, Nature
(Details)(Pubmed ID: 21772288)
Times cited: 1520
- Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins.
Shaya D, Kreir M, Robbins RA, Wong S, Hammon J, BrüggeMAnn A, Minor DL
CSMP, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 21746903)
Times cited: 54
- Physiological response to membrane protein overexpression in E. coli.
Gubellini F, Verdon G, Karpowich NK, Luff JD, Boël G, Gauthier N, HandelMAn SK, Ades SE, Hunt JF
NYCOMPS, Molecular & Cellular Proteomics
(Details)(Pubmed ID: 21719796)
Times cited: 21
- A peroxisome proliferator-activated receptor gamMA (PPARgamMA)/PPARgamMA coactivator 1beta autoregulatory loop in adipocyte mitochondrial function.
Deng T, Sieglaff DH, Zhang A, Lyon CJ, Ayers SD, Cvoro A, Gupte AA, Xia X, Baxter JD, Webb P, Hsueh WA
STEMCELL, Journal of Biological Chemistry
(Details)(Pubmed ID: 21719705)
Times cited: 18
- Structure of the huMAn histamine H-1 receptor complex with doxepin
ShiMAmura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S
GPCR, Nature
(Details)(Pubmed ID: 21697825)
PDB ID(s): 3RZE
Times cited: 476
- MArkUs: a server to navigate sequence-structure-function space.
Fischer M, Zhang QC, Dey F, Chen BY, Honig B, Petrey D
NESG, Nucleic Acids Research
(Details)(Pubmed ID: 21672961)
Times cited: 10
- The Gene3D Web Services: a platform for identifying, annotating and comparing structural doMAins in protein sequences.
Yeats C, Lees J, Carter P, Sillitoe I, Orengo C
CSGID, Nucleic Acids Research
(Details)(Pubmed ID: 21646335)
Times cited: 10
- Improved technologies now routinely provide protein NMR structures useful for molecular replacement.
MAo B, Guan R, Montelione GT
NESG, Structure
(Details)(Pubmed ID: 21645849)
Times cited: 28
- UNC119 is required for G protein trafficking in sensory neurons.
Zhang H, Constantine R, Vorobiev S, Chen Y, SeetharaMAn J, Huang YJ, Xiao R, Montelione GT, Gerstner CD, Davis MW, Inana G, Whitby FG, Jorgensen EM, Hill CP, Tong L, Baehr W
NESG, Nature neuroscience
(Details)(Pubmed ID: 21642972)
Times cited: 89
- Mutation of the His ligand in mitoNEET stabilizes the 2Fe-2S cluster despite conforMAtional heterogeneity in the ligand environment.
Conlan AR, Paddock ML, Homer C, Axelrod HL, Cohen AE, Abresch EC, Zuris JA, Nechushtai R, Jennings PA
JCSG, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 21636891)
PDB ID(s): 3LPQ
Times cited: 19
- Structure of the guanylyltransferase doMAin of huMAn mRNA capping enzyme.
Chu C, Das K, Tyminski JR, BauMAn JD, Guan R, Qiu W, Montelione GT, Arnold E, Shatkin AJ
NESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 21636784)
Times cited: 14
- Crystal structure of the novel PaiA N-acetyltransferase from ThermoplasMA acidophilum involved in the negative control of sporulation and degradative enzyme production.
Filippova EV, Shuvalova L, Minasov G, Kiryukhina O, Zhang Y, Clancy S, Radhakrishnan I, Joachimiak A, Anderson WF
MCSG, Proteins
(Details)(Pubmed ID: 21633970)
Times cited: 8
- Dimer Interface of the Effector DoMAin of Non-structural Protein 1 from Influenza A Virus: AN INTERFACE WITH MULTIPLE FUNCTIONS.
Aramini JM, MA LC, Zhou L, Schauder CM, Hamilton K, Amer BR, MAck TR, Lee HW, Ciccosanti CT, Zhao L, Xiao R, Krug RM, Montelione GT
NESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 21622573)
Times cited: 31
- Structural Analysis of a Putative Aminoglycoside N-Acetyltransferase from Bacillus anthracis.
Klimecka MM, Chruszcz M, Font J, Skarina T, Shumilin I, Onopryienko O, Porebski PJ, Cymborowski M, ZimmerMAn MD, HasseMAn J, Glomski IJ, Lebioda L, Savchenko A, Edwards A, Minor W
CSGID, Journal of Molecular Biology
(Details)(Pubmed ID: 21601576)
Times cited: 9
- Structure of surface layer homology (SLH) doMAins from Bacillus anthracis surface array protein.
Kern J, Wilton R, Zhang R, Binkowski TA, Joachimiak A, Schneewind O
MCSG, Journal of Biological Chemistry
(Details)(Pubmed ID: 21572039)
PDB ID(s): 3PYW
Times cited: 49
- Backbone and Ile-δ1, Leu, Val methyl 1H, 13C and 15N NMR chemical shift assignments for huMAn interferon-stimulated gene 15 protein.
Yin C, Aramini JM, MA LC, Cort JR, Swapna GV, Krug RM, Montelione GT
NESG, Biomolecular NMR Assignments
(Details)(Pubmed ID: 21544738)
Times cited: 0
- Crystal structure of a metal-dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activity.
Han GW, Ko J, Farr CL, Deller MC, Xu Q, Chiu HJ, Miller MD, Sefcikova J, SoMArowthu S, Beuning PJ, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA, Ondrechen MJ
JCSG, Proteins
(Details)(Pubmed ID: 21538547)
PDB ID(s): 3E0F 3O0F
Times cited: 11
- Improved molecular replacement by density- and energy-guided protein structure optimization.
DiMAio F, Terwilliger TC, Read RJ, Wlodawer A, Oberdorfer G, Wagner U, Valkov E, Alon A, Fass D, Axelrod HL, Das D, Vorobiev SM, Iwaï H, Pokkuluri PR, Baker D
JCSG+NESG, Nature
(Details)(Pubmed ID: 21532589)
Times cited: 150
- Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors.
You L, Cho EJ, Leavitt J, MA LC, Montelione GT, Anslyn EV, Krug RM, Ellington A, Robertus JD
NESG, Accounts of Chemical Research
(Details)(Pubmed ID: 21478016)
Times cited: 30
- A dynamic knockout reveals that conforMAtional fluctuations influence the chemical step of enzyme catalysis.
Bhabha G, Lee J, Ekiert DC, Gam J, Wilson IA, Dyson HJ, Benkovic SJ, Wright PE
JCSG, Science
(Details)(Pubmed ID: 21474759)
Times cited: 270
- The Structural Biology Knowledgebase: a portal to protein structures, sequences, functions, and methods.
Gabanyi MJ, Adams PD, Arnold K, Bordoli L, Carter LG, Flippen-Andersen J, Gifford L, Haas J, Kouranov A, McLaughlin WA, Micallef DI, Minor W, Shah R, Schwede T, Tao YP, Westbrook JD, ZimmerMAn M, BerMAn HM
PSISBKB, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 21472436)
Times cited: 42
- Determination of the structures of symmetric protein oligomers from NMR chemical shifts and residual dipolar couplings.
Sgourakis NG, Lange OF, DiMAio F, André I, Fitzkee NC, Rossi P, Montelione GT, Bax A, Baker D
NESG, Journal of the American Chemical Society
(Details)(Pubmed ID: 21466200)
Times cited: 42
- Residues within a lipid-associated segment of the PECAM-1 cytoplasmic doMAin are susceptible to inducible, sequential phosphorylation.
Paddock C, Lytle BL, Peterson FC, Holyst T, NewMAn PJ, VolkMAn BF, NewMAn DK
CESG, Blood
(Details)(Pubmed ID: 21464369)
PDB ID(s): 2KY5
Times cited: 19
- SMAll angle X-ray scattering as a complementary tool for high-throughput structural studies.
Grant TD, Luft JR, Wolfley JR, Tsuruta H, MArtel A, Montelione GT, Snell EH
NESG, Biopolymers
(Details)(Pubmed ID: 21462184)
Times cited: 39
- Structure of gamMA-secretase and its trimeric pre-activation intermediate by single-particle electron microscopy.
Renzi F, Zhang X, Rice WJ, Torres-Arancivia C, Gomez-Llorente Y, Diaz R, Ahn K, Yu C, Li YM, Sisodia SS, Ubarretxena-Belandia I.
TEMIMPS, Journal of Biological Chemistry
(Details)(Pubmed ID: 21456411)
Times cited: 28
- Structure and function of the first full-length murein Peptide ligase (mpl) cell wall recycling protein.
Das D, Hervé M, Feuerhelm J, Farr CL, Chiu HJ, Elsliger MA, Knuth MW, Klock HE, Miller MD, Godzik A, Lesley SA, Deacon AM, Mengin-Lecreulx D, Wilson IA
JCSG, PLoS ONE
(Details)(Pubmed ID: 21445265)
PDB ID(s): 3HN7
Times cited: 9
- Interferon-inducible protein 16: insight into the interaction with tumor suppressor p53.
Liao JC, Lam R, Brazda V, Duan S, Ravichandran M, MA J, Xiao T, Tempel W, Zuo X, Wang YX, Chirgadze NY, Arrowsmith CH
NESG, Structure
(Details)(Pubmed ID: 21397192)
Times cited: 47
- Structure of an agonist-bound huMAn A2A adenosine receptor.
Xu F, Wu H, Katritch V, Han GW, Jacobson KA, Gao ZG, Cherezov V, Stevens RC
GPCR, Science
(Details)(Pubmed ID: 21393508)
PDB ID(s): 3QAK
Times cited: 532
- Crystal structure of an integron gene cassette-associated protein from Vibrio cholerae identifies a cationic drug-binding module.
Deshpande CN, Harrop SJ, Boucher Y, Hassan KA, Di Leo R, Xu X, Cui H, Savchenko A, Chang C, Labbate M, Paulsen IT, Stokes HW, Curmi PM, MAbbutt BC
MCSG, PLoS ONE
(Details)(Pubmed ID: 21390267)
PDB ID(s): 3GK6
Times cited: 9
- Structural basis for a ribofuranosyl binding protein: Insights into the furanose specific transport.
Bagaria A, KuMAran D, Burley SK, Swaminathan S
NYSGXRC, Proteins
(Details)(Pubmed ID: 21387413)
PDB ID(s): 3KSM
Times cited: 3
- Structure of the C-terminal heme-binding doMAin of THAP doMAin containing protein 4 from Homo sapiens.
Bianchetti CM, BingMAn CA, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 21387410)
PDB ID(s): 3IA8
Times cited: 8
- Structural architecture of Galdieria sulphuraria DCN1L.
Sethe Burgie E, BingMAn CA, MAkino S, Wesenberg GE, Pan X, Fox BG, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 21387409)
PDB ID(s): 3KEV
Times cited: 1
- Binding site identification and structure determination of protein-ligand complexes by NMR a semiautoMAted approach.
Ziarek JJ, Peterson FC, Lytle BL, VolkMAn BF
CESG, Methods in Enzymology
(Details)(Pubmed ID: 21371594)
Times cited: 33
- Preparation of protein samples for NMR structure, function, and sMAll-molecule screening studies.
Acton TB, Xiao R, Anderson S, Aramini J, Buchwald WA, Ciccosanti C, Conover K, Everett J, Hamilton K, Huang YJ, Janjua H, Kornhaber G, Lau J, Lee DY, Liu G, MAglaqui M, MA L, MAo L, Patel D, Rossi P, Sahdev S, Shastry R, Swapna GV, Tang Y, Tong S, Wang D, Wang H, Zhao L, Montelione GT
NESG, Methods in Enzymology
(Details)(Pubmed ID: 21371586)
Times cited: 60
- PSI:Biology-MAterials repository: a biologist's resource for protein expression plasmids.
Cormier CY, Park JG, Fiacco M, Steel J, Hunter P, Kramer J, Singla R, LaBaer J
PSIMR, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 21360289)
Times cited: 36
- Recovery of intact DNA nanostructures after agarose gel-based separation.
Bellot G, McClintock MA, Lin C, Shih WM
MPSbyNMR, Nature Methods
(Details)(Pubmed ID: 21358621)
Times cited: 45
- Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway.
Chang A, Singh S, BingMAn CA, Thorson JS, Phillips GN
CESG, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 21358050)
PDB ID(s): 3LST
Times cited: 9
- Crystal structure of a potassium ion transporter, TrkH.
Cao Y, Jin X, Huang H, Derebe MG, Levin EJ, Kabaleeswaran V, Pan Y, Punta M, Love J, Weng J, Quick M, Ye S, Kloss B, Bruni R, MArtinez-Hackert E, Hendrickson WA, Rost B, Javitch JA, Rajashankar KR, Jiang Y, Zhou M
NYCOMPS, Nature
(Details)(Pubmed ID: 21317882)
PDB ID(s): 3PJZ
Times cited: 67
- Expanding the nucleotide and sugar-1-phosphate promiscuity of nucleotidyltransferase RmlA via directed evolution.
Moretti R, Chang A, Peltier-Pain P, BingMAn CA, Phillips GN, Thorson JS
CESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 21317292)
PDB ID(s): 3PKP 3PKQ
Times cited: 25
- Femtosecond X-ray protein nanocrystallography.
ChapMAn HN, Fromme P, Barty A, White TA, Kirian RA, Aquila A, Hunter MS, Schulz J, DePonte DP, Weierstall U, Doak RB, MAia FR, MArtin AV, Schlichting I, Lomb L, Coppola N, ShoeMAn RL, Epp SW, HartMAnn R, Rolles D, Rudenko A, Foucar L, Kimmel N, Weidenspointner G, Holl P, Liang M, Barthelmess M, CaleMAn C, Boutet S, Bogan MJ, Krzywinski J, Bostedt C, Bajt S, Gumprecht L, Rudek B, Erk B, Schmidt C, Hömke A, Reich C, Pietschner D, Strüder L, Hauser G, Gorke H, Ullrich J, HerrMAnn S, Schaller G, Schopper F, Soltau H, Kühnel KU, Messerschmidt M, Bozek JD, Hau-Riege SP, Frank M, Hampton CY, Sierra RG, Starodub D, Williams GJ, Hajdu J, Timneanu N, Seibert MM, Andreasson J, Rocker A, Jönsson O, Svenda M, Stern S, Nass K, Andritschke R, Schröter CD, Krasniqi F, Bott M, Schmidt KE, Wang X, Grotjohann I, Holton JM, Barends TR, Neutze R, MArchesini S, Fromme R, Schorb S, Rupp D, Adolph M, Gorkhover T, Andersson I, HirseMAnn H, Potdevin G, GraafsMA H, Nilsson B, Spence JC
MPID, Nature
(Details)(Pubmed ID: 21293373)
Times cited: 996
- Suppression of phospholipid biosynthesis by cerulenin in the condensed Single-Protein-Production (cSPP) system.
MAo L, Inoue K, Tao Y, Montelione GT, McDermott AE, Inouye M
NESG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 21279668)
Times cited: 10
- EnzyMAtic deamination of the epigenetic base N-6-methyladenine.
KaMAt SS, Fan H, Sauder JM, Burley SK, Shoichet BK, Sali A, Raushel FM
NYSGXRC, Journal of the American Chemical Society
(Details)(Pubmed ID: 21275375)
Times cited: 16
- Crystal Structure of the HuMAn N-Myc Downstream-regulated Gene 2 Protein Provides Insight into Its Role as a Tumor Suppressor.
Hwang J, Kim Y, Kang HB, Jaroszewski L, Deacon AM, Lee H, Choi WC, Kim KJ, Kim CH, Kang BS, Lee JO, Oh TK, Kim JW, Wilson IA, Kim MH
JCSG, Journal of Biological Chemistry
(Details)(Pubmed ID: 21247902)
PDB ID(s): 2XMQ 2XMR 2XMS 2QMQ
Times cited: 39
- Catalytic mechanism and three-dimensional structure of adenine deaminase.
KaMAt SS, Bagaria A, KuMAran D, Holmes-Hampton GP, Fan H, Sali A, Sauder JM, Burley SK, Lindahl PA, Swaminathan S, Raushel FM
EFI+NYSGXRC, Biochemistry
(Details)(Pubmed ID: 21247091)
Times cited: 24
- Solution structure of 4'-phosphopantetheine - GMACP3 from Geobacter metallireducens: a specialized acyl carrier protein with atypical structural features and a putative role in lipopolysaccharide biosynthesis.
Ramelot TA, Smola MJ, Lee HW, Ciccosanti C, Hamilton K, Acton TB, Xiao R, Everett JK, Prestegard JH, Montelione GT, Kennedy MA
NESG, Biochemistry
(Details)(Pubmed ID: 21235239)
Times cited: 6
- Multi-crystal anoMAlous diffraction for low-resolution MAcromolecular phasing.
Liu Q, Zhang Z, Hendrickson WA
NYCOMPS, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 21206061)
Times cited: 39
- A novel strategy for NMR resonance assignment and protein structure determination.
LeMAk A, GutMAnas A, Chitayat S, Karra M, Farès C, Sunnerhagen M, Arrowsmith CH
NESG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 21161328)
Times cited: 30
- Structures of doMAins I and IV from YbbR are representative of a widely distributed protein family.
Barb AW, Cort JR, SeetharaMAn J, Lew S, Lee HW, Acton T, Xiao R, Kennedy MA, Tong L, Montelione GT, Prestegard JH
NESG, Protein Science
(Details)(Pubmed ID: 21154411)
Times cited: 10
- Solution NMR and X-ray crystal structures of membrane-associated Lipoprotein-17 doMAin reveal a novel fold.
MAni R, Vorobiev S, Swapna GV, Neely H, Janjua H, Ciccosanti C, Xiao R, Acton TB, Everett JK, Hunt J, Montelione GT
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 21153711)
Times cited: 0
- A hybrid structural model of the complete Brugia MAlayi cytoplasmic asparaginyl-tRNA synthetase.
Crepin T, Peterson F, Haertlein M, Jensen D, Wang C, Cusack S, Kron M
CESG, Journal of Molecular Biology
(Details)(Pubmed ID: 21134380)
PDB ID(s): 2KQR
Times cited: 24
- ModBase, a database of annotated comparative protein structure models, and associated resources.
Pieper U, Webb BM, Barkan DT, SchneidMAn-Duhovny D, Schlessinger A, Braberg H, Yang Z, Meng EC, Pettersen EF, Huang CC, Datta RS, SampathkuMAr P, MAdhusudhan MS, Sjölander K, Ferrin TE, Burley SK, Sali A
NYSGXRC, Nucleic Acids Research
(Details)(Pubmed ID: 21097780)
Times cited: 175
- Synthetic symmetrization in the crystallization and structure determination of CelA from Thermotoga MAritiMA.
Forse GJ, Ram N, Banatao DR, Cascio D, Sawaya MR, Klock HE, Lesley SA, Yeates TO
JCSG, Protein Science
(Details)(Pubmed ID: 21082721)
Times cited: 10
- Solution NMR structure of photosystem II reaction center protein Psb28 from Synechocystis sp. Strain PCC 6803.
Yang Y, Ramelot TA, Cort JR, Wang D, Ciccosanti C, Hamilton K, Nair R, Rost B, Acton TB, Xiao R, Everett JK, Montelione GT, Kennedy MA
NESG, Proteins
(Details)(Pubmed ID: 21058299)
Times cited: 15
- Solution NMR structure of the plasmid-encoded fimbriae regulatory protein PefI from Salmonella enterica serovar Typhimurium.
Aramini JM, Rossi P, Cort JR, MA LC, Xiao R, Acton TB, Montelione GT
NESG, Proteins
(Details)(Pubmed ID: 20979070)
Times cited: 0
- TOPSAN: a dynamic web database for structural genomics.
Ellrott K, ZMAsek CM, Weekes D, Sri Krishna S, Bakolitsa C, Godzik A, Wooley J
JCMM+JCSG, Nucleic Acids Research
(Details)(Pubmed ID: 20961957)
Times cited: 13
- Robotic large-scale application of wheat cell-free translation to structural studies including membrane proteins.
Beebe ET, MAkino SI, Nozawa A, MAtsubara Y, Frederick RO, Primm JG, Goren MA, Fox BG
CESG, New biotechnology
(Details)(Pubmed ID: 20637905)
Times cited: 14
2010
- Structure of the iSH2 doMAin of huMAn phosphatidylinositol 3-kinase p85β subunit reveals conforMAtional plasticity in the interhelical turn region.
Schauder C, MA LC, Krug RM, Montelione GT, Guan R
NESG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 21139197)
Times cited: 3
- Structures of bacterial biosynthetic arginine decarboxylases.
Forouhar F, Lew S, SeetharaMAn J, Xiao R, Acton TB, Montelione GT, Tong L
NESG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 21139196)
Times cited: 4
- Structure of the huMAn dopamine D3 receptor in complex with a D2/D3 selective antagonist.
Chien EY, Liu W, Zhao Q, Katritch V, Han GW, Hanson MA, Shi L, NewMAn AH, Javitch JA, Cherezov V, Stevens RC
ATCG3D+GPCR, Science
(Details)(Pubmed ID: 21097933)
PDB ID(s): 3PBL
Times cited: 729
- Detailed analysis of function divergence in a large and diverse doMAin superfamily: toward a refined protocol of function classification.
Dessailly BH, Redfern OC, Cuff AL, Orengo CA
MCSG, Structure
(Details)(Pubmed ID: 21070951)
Times cited: 15
- Structural underpinnings of nitrogen regulation by the prototypical nitrogen-responsive transcriptional factor NrpR.
Wisedchaisri G, Dranow DM, Lie TJ, Bonanno JB, Patskovsky Y, Ozyurt SA, Sauder JM, Almo SC, WasserMAn SR, Burley SK, Leigh JA, Gonen T
NYSGXRC, Structure
(Details)(Pubmed ID: 21070950)
PDB ID(s): 3NEK
Times cited: 6
- MAltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins.
Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Chandra R, Goren MA, Kruse AC, Nurva S, Loland CJ, Pierre Y, Drew D, Popot JL, Picot D, Fox BG, Guan L, Gether U, Byrne B, Kobilka B, GellMAn SH
CESG+TMPC, Nature Methods
(Details)(Pubmed ID: 21037590)
Times cited: 199
- Homologue structure of the SLAC1 anion channel for closing stoMAta in leaves.
Chen YH, Hu L, Punta M, Bruni R, Hillerich B, Kloss B, Rost B, Love J, Siegelbaum SA, Hendrickson WA
NYCOMPS, Nature
(Details)(Pubmed ID: 20981093)
PDB ID(s): 3M71 3M72 3M73 3M74 3M75 3M76 3M77 3M78 3M7B 3M7C 3M7E 3M7L
Times cited: 70
- S-Adenosylmethionine-dependent radical-based modification of biological MAcromolecules.
Atta M, Mulliez E, Arragain S, Forouhar F, Hunt JF, Fontecave M
NESG, Current Opinion in Structural Biology
(Details)(Pubmed ID: 20951571)
Times cited: 32
- DoMAin view: a web tool for protein doMAin visualization and analysis.
Pan X, BingMAn CA, Wesenberg GE, Sun Z, Phillips GN
CESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 20945103)
Times cited: 2
- Comparison of NMR and crystal structures highlights conforMAtional isomerism in protein active sites.
Serrano P, Pedrini B, Geralt M, Jaudzems K, Mohanty B, Horst R, HerrMAnn T, Elsliger MA, Wilson IA, Wüthrich K
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944236)
PDB ID(s): 2KA5 2KL2
Times cited: 13
- Comparison of NMR and crystal structures for the proteins TM1112 and TM1367.
Mohanty B, Serrano P, Pedrini B, Jaudzems K, Geralt M, Horst R, HerrMAnn T, Elsliger MA, Wilson IA, Wüthrich K
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944235)
PDB ID(s): 2K9Z 2KA0
Times cited: 11
- NMR structure of the protein NP_247299.1: comparison with the crystal structure.
Jaudzems K, Geralt M, Serrano P, Mohanty B, Horst R, Pedrini B, Elsliger MA, Wilson IA, Wüthrich K
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944234)
PDB ID(s): 2KLA
Times cited: 13
- Structure of the γ-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-γ-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases.
Xu Q, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Cai X, Carlton D, Chen C, Chiu HJ, Chiu M, Clayton T, Das D, Deller MC, Duan L, Ellrott K, Farr CL, Feuerhelm J, Grant JC, Grzechnik A, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, KuMAr A, Lam WW, MArciano D, Miller MD, Morse AT, Nigoghossian E, Nopakun A, Okach L, Puckett C, Reyes R, Tien HJ, Trame CB, van den Bedem H, Weekes D, Wooten T, Yeh A, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944232)
PDB ID(s): 3H41
Times cited: 37
- ConforMAtional changes associated with the binding of zinc acetate at the putative active site of XcTcmJ, a cupin from Xanthomonas campestris pv. campestris.
Axelrod HL, Kozbial P, McMullan D, Krishna SS, Miller MD, Abdubek P, Acosta C, Astakhova T, Carlton D, Caruthers J, Chiu HJ, Clayton T, Deller MC, Duan L, Elias Y, Feuerhelm J, Grzechnik SK, Grant JC, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, KuMAr A, MArciano D, Morse AT, Murphy KD, Nigoghossian E, Okach L, OomMAchen S, Paulsen J, Reyes R, Rife CL, Tien HJ, Trout CV, van den Bedem H, Weekes D, White A, Xu Q, Zubieta C, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944231)
PDB ID(s): 3H50
Times cited: 5
- Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved α+β core doMAin and an auxiliary C-terminal treble-clef zinc finger.
Axelrod HL, Das D, Abdubek P, Astakhova T, Bakolitsa C, Carlton D, Chen C, Chiu HJ, Clayton T, Deller MC, Duan L, Ellrott K, Farr CL, Feuerhelm J, Grant JC, Grzechnik A, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, KuMAr A, Lam WW, MArciano D, McMullan D, Miller MD, Morse AT, Nigoghossian E, Nopakun A, Okach L, Puckett C, Reyes R, Sefcovic N, Tien HJ, Trame CB, van den Bedem H, Weekes D, Wooten T, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944230)
PDB ID(s): 2GLZ 2GVI 3D00
Times cited: 5
- Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster.
Han GW, Yang XL, McMullan D, Chong YE, Krishna SS, Rife CL, Weekes D, Brittain SM, Abdubek P, Ambing E, Astakhova T, Axelrod HL, Carlton D, Caruthers J, Chiu HJ, Clayton T, Duan L, Feuerhelm J, Grant JC, Grzechnik SK, Jaroszewski L, Jin KK, Klock HE, Knuth MW, KuMAr A, MArciano D, Miller MD, Morse AT, Nigoghossian E, Okach L, Paulsen J, Reyes R, van den Bedem H, White A, Wolf G, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Elsliger MA, Schimmel P, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944229)
PDB ID(s): 2G36
Times cited: 17
- The structure of Haemophilus influenzaeprephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes.
Chiu HJ, Abdubek P, Astakhova T, Axelrod HL, Carlton D, Clayton T, Das D, Deller MC, Duan L, Feuerhelm J, Grant JC, Grzechnik A, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, KuMAr A, MArciano D, McMullan D, Miller MD, Morse AT, Nigoghossian E, Okach L, Reyes R, Tien HJ, Trame CB, van den Bedem H, Weekes D, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944228)
PDB ID(s): 2PV7
Times cited: 7
- Ligands in PSI structures.
KuMAr A, Chiu HJ, Axelrod HL, Morse A, Elsliger MA, Wilson IA, Deacon A
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944227)
Times cited: 11
- Structure of a membrane-attack complex/perforin (MACPF) family protein from the huMAn gut symbiont Bacteroides thetaiotaomicron.
Xu Q, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Cai X, Carlton D, Chen C, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Ellrott K, Farr CL, Feuerhelm J, Grant JC, Grzechnik A, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, KuMAr A, Lam WW, MArciano D, Miller MD, Morse AT, Nigoghossian E, Nopakun A, Okach L, Puckett C, Reyes R, Tien HJ, Trame CB, van den Bedem H, Weekes D, Wooten T, Yeh A, Zhou J, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944225)
PDB ID(s): 3KK7
Times cited: 16
- Structure of Bacteroides thetaiotaomicron BT2081 at 2.05 Å resolution: the first structural representative of a new protein family that MAy play a role in carbohydrate metabolism.
Yeh AP, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Cai X, Carlton D, Chen C, Chiu HJ, Chiu M, Clayton T, Das D, Deller MC, Duan L, Ellrott K, Farr CL, Feuerhelm J, Grant JC, Grzechnik A, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, KuMAr A, Lam WW, MArciano D, McMullan D, Miller MD, Morse AT, Nigoghossian E, Nopakun A, Okach L, Puckett C, Reyes R, Tien HJ, Trame CB, van den Bedem H, Weekes D, Wooten T, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944224)
PDB ID(s): 3HBZ
Times cited: 1
- A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Å resolution.
Xu Q, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Cai X, Carlton D, Chen C, Chiu HJ, Chiu M, Clayton T, Das D, Deller MC, Duan L, Ellrott K, Farr CL, Feuerhelm J, Grant JC, Grzechnik A, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, KuMAr A, MArciano D, McMullan D, Miller MD, Morse AT, Nigoghossian E, Nopakun A, Okach L, Puckett C, Reyes R, Sefcovic N, Tien HJ, Trame CB, van den Bedem H, Weekes D, Wooten T, Yeh A, Zhou J, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944223)
PDB ID(s): 3GF8
Times cited: 6
- Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules.
Bakolitsa C, Xu Q, Rife CL, Abdubek P, Astakhova T, Axelrod HL, Carlton D, Chen C, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Ellrott K, Farr CL, Feuerhelm J, Grant JC, Grzechnik A, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, KuMAr A, Lam WW, MArciano D, McMullan D, Miller MD, Morse AT, Nigoghossian E, Nopakun A, Okach L, Puckett C, Reyes R, Tien HJ, Trame CB, van den Bedem H, Weekes D, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944222)
PDB ID(s): 3CGH
Times cited: 6
- The structure of BVU2987 from Bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory function.
Das D, Finn RD, Carlton D, Miller MD, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Chen C, Chiu HJ, Chiu M, Clayton T, Deller MC, Duan L, Ellrott K, Ernst D, Farr CL, Feuerhelm J, Grant JC, Grzechnik A, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, KuMAr A, MArciano D, McMullan D, Morse AT, Nigoghossian E, Nopakun A, Okach L, Puckett C, Reyes R, Rife CL, Sefcovic N, Tien HJ, Trame CB, van den Bedem H, Weekes D, Wooten T, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944221)
PDB ID(s): 3DUE
Times cited: 7
- Viewing the huMAn microbiome through three-dimensional glasses: integrating structural and functional studies to better define the properties of myriad carbohydrate-active enzymes.
Turnbaugh PJ, Henrissat B, Gordon JI
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944220)
Times cited: 21
- The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-fold.
Das D, Kozbial P, Han GW, Carlton D, Jaroszewski L, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Chen C, Chiu HJ, Chiu M, Clayton T, Deller MC, Duan L, Ellrott K, Elsliger MA, Ernst D, Farr CL, Feuerhelm J, Grzechnik A, Grant JC, Jin KK, Johnson HA, Klock HE, Knuth MW, Krishna SS, KuMAr A, MArciano D, McMullan D, Miller MD, Morse AT, Nigoghossian E, Nopakun A, Okach L, OomMAchen S, Paulsen J, Puckett C, Reyes R, Rife CL, Sefcovic N, Tien HJ, Trame CB, van den Bedem H, Weekes D, Wooten T, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944219)
PDB ID(s): 3F1Z
Times cited: 2
- Open and closed conforMAtions of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding.
KuMAr A, Lomize A, Jin KK, Carlton D, Miller MD, Jaroszewski L, Abdubek P, Astakhova T, Axelrod HL, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Feuerhelm J, Grant JC, Grzechnik A, Han GW, Klock HE, Knuth MW, Kozbial P, Krishna SS, MArciano D, McMullan D, Morse AT, Nigoghossian E, Okach L, Reyes R, Rife CL, Sefcovic N, Tien HJ, Trame CB, van den Bedem H, Weekes D, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944218)
PDB ID(s): 2OOK 2Q3L
Times cited: 6
- Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15.
Han GW, Elsliger MA, Yeates TO, Xu Q, Murzin AG, Krishna SS, Jaroszewski L, Abdubek P, Astakhova T, Axelrod HL, Carlton D, Chen C, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Ernst D, Feuerhelm J, Grant JC, Grzechnik A, Jin KK, Johnson HA, Klock HE, Knuth MW, Kozbial P, KuMAr A, Lam WW, MArciano D, McMullan D, Miller MD, Morse AT, Nigoghossian E, Okach L, Reyes R, Rife CL, Sefcovic N, Tien HJ, Trame CB, van den Bedem H, Weekes D, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944217)
PDB ID(s): 3NL9
Times cited: 2
- Structure of an essential bacterial protein YeaZ (TM0874) from Thermotoga MAritiMA at 2.5 Å resolution
Xu Q, McMullan D, Jaroszewski L, Krishna SS, Elsliger MA, Yeh AP, Abdubek P, Astakhova T, Axelrod HL, Carlton D, Chiu HJ, Clayton T, Duan L, Feuerhelm J, Grant J, Han GW, Jin KK, Klock HE, Knuth MW, Miller MD, Morse AT, Nigoghossian E, Okach L, OomMAchen S, Paulsen J, Reyes R, Rife CL, van den Bedem H, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944216)
PDB ID(s): 2A6A
Times cited: 11
- Structures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transduction.
Han GW, Bakolitsa C, Miller MD, KuMAr A, Carlton D, NajMAnovich RJ, Abdubek P, Astakhova T, Axelrod HL, Chen C, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Ernst D, Feuerhelm J, Grant JC, Grzechnik A, Jaroszewski L, Jin KK, Johnson HA, Klock HE, Knuth MW, Kozbial P, Krishna SS, MArciano D, McMullan D, Morse AT, Nigoghossian E, Okach L, Reyes R, Rife CL, Sefcovic N, Tien HJ, Trame CB, van den Bedem H, Weekes D, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944214)
PDB ID(s): 2RE3 2RA9
Times cited: 6
- The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolism.
Bakolitsa C, KuMAr A, McMullan D, Krishna SS, Miller MD, Carlton D, NajMAnovich R, Abdubek P, Astakhova T, Chiu HJ, Clayton T, Deller MC, Duan L, Elias Y, Feuerhelm J, Grant JC, Grzechnik SK, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, MArciano D, Morse AT, Nigoghossian E, Okach L, OomMAchen S, Paulsen J, Reyes R, Rife CL, Trout CV, van den Bedem H, Weekes D, White A, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944213)
PDB ID(s): 2H1T
Times cited: 5
- Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism.
Bakolitsa C, KuMAr A, Carlton D, Miller MD, Krishna SS, Abdubek P, Astakhova T, Axelrod HL, Chiu HJ, Clayton T, Deller MC, Duan L, Elsliger MA, Feuerhelm J, Grzechnik SK, Grant JC, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, MArciano D, McMullan D, Morse AT, Nigoghossian E, Okach L, OomMAchen S, Paulsen J, Reyes R, Rife CL, Tien HJ, Trout CV, van den Bedem H, Weekes D, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944212)
PDB ID(s): 2IAY
Times cited: 1
- The structure of Jann_2411 (DUF1470) from Jannaschia sp. at 1.45 Å resolution reveals a new fold (the ABATE doMAin) and suggests its possible role as a transcription regulator
Bakolitsa C, BateMAn A, Jin KK, McMullan D, Krishna SS, Miller MD, Abdubek P, Acosta C, Astakhova T, Axelrod HL, Burra P, Carlton D, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Elias Y, Feuerhelm J, Grant JC, Grzechnik A, Grzechnik SK, Han GW, Jaroszewski L, Klock HE, Knuth MW, Kozbial P, KuMAr A, MArciano D, Morse AT, Murphy KD, Nigoghossian E, Okach L, OomMAchen S, Paulsen J, Reyes R, Rife CL, Sefcovic N, Tien H, Trame CB, Trout CV, van den Bedem H, Weekes D, White A, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley S, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944211)
PDB ID(s): 3H0N
Times cited: 6
- Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorisMAte mutase fold and suggest a role in amino-acid metabolism.
Bakolitsa C, KuMAr A, Jin KK, McMullan D, Krishna SS, Miller MD, Abdubek P, Acosta C, Astakhova T, Axelrod HL, Burra P, Carlton D, Chen C, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Elias Y, Ellrott K, Ernst D, Farr CL, Feuerhelm J, Grant JC, Grzechnik A, Grzechnik SK, Han GW, Jaroszewski L, Johnson HA, Klock HE, Knuth MW, Kozbial P, MArciano D, Morse AT, Murphy KD, Nigoghossian E, Nopakun A, Okach L, Paulsen J, Puckett C, Reyes R, Rife CL, Sefcovic N, Tien HJ, Trame CB, Trout CV, van den Bedem H, Weekes D, White A, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944209)
PDB ID(s): 3BYQ 2QTP
Times cited: 1
- The structure of the first representative of Pfam family PF09836 reveals a two-doMAin organization and suggests involvement in transcriptional regulation.
Das D, Grishin NV, KuMAr A, Carlton D, Bakolitsa C, Miller MD, Abdubek P, Astakhova T, Axelrod HL, Burra P, Chen C, Chiu HJ, Chiu M, Clayton T, Deller MC, Duan L, Ellrott K, Ernst D, Farr CL, Feuerhelm J, Grzechnik A, Grzechnik SK, Grant JC, Han GW, Jaroszewski L, Jin KK, Johnson HA, Klock HE, Knuth MW, Kozbial P, Krishna SS, MArciano D, McMullan D, Morse AT, Nigoghossian E, Nopakun A, Okach L, OomMAchen S, Paulsen J, Puckett C, Reyes R, Rife CL, Sefcovic N, Tien HJ, Trame CB, van den Bedem H, Weekes D, Wooten T, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944208)
PDB ID(s): 3DEE
Times cited: 3
- Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and RossMAnn-like folds that combine to form a unique active site with a possible role in heavy-metal chelation.
Miller MD, Aravind L, Bakolitsa C, Rife CL, Carlton D, Abdubek P, Astakhova T, Axelrod HL, Chiu HJ, Clayton T, Deller MC, Duan L, Feuerhelm J, Grant JC, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, KuMAr A, MArciano D, McMullan D, Morse AT, Nigoghossian E, Okach L, Reyes R, van den Bedem H, Weekes D, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944207)
PDB ID(s): 3L5O
Times cited: 0
- The structure of SSO2064, the first representative of Pfam family PF01796, reveals a novel two-doMAin zinc-ribbon OB-fold architecture with a potential acyl-CoA-binding role.
Krishna SS, Aravind L, Bakolitsa C, Caruthers J, Carlton D, Miller MD, Abdubek P, Astakhova T, Axelrod HL, Chiu HJ, Clayton T, Deller MC, Duan L, Feuerhelm J, Grant JC, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, KuMAr A, MArciano D, McMullan D, Morse AT, Nigoghossian E, Okach L, Reyes R, Rife CL, van den Bedem H, Weekes D, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944206)
PDB ID(s): 3IRB
Times cited: 10
- Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism.
Chiu HJ, Bakolitsa C, Skerra A, Lomize A, Carlton D, Miller MD, Krishna SS, Abdubek P, Astakhova T, Axelrod HL, Clayton T, Deller MC, Duan L, Feuerhelm J, Grant JC, Grzechnik SK, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, KuMAr A, MArciano D, McMullan D, Morse AT, Nigoghossian E, Okach L, Paulsen J, Reyes R, Rife CL, van den Bedem H, Weekes D, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944205)
PDB ID(s): 2ICH
Times cited: 9
- DUFs: families in search of function.
BateMAn A, Coggill P, Finn RD
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944204)
Times cited: 88
- TOPSAN: use of a collaborative environment for annotating, analyzing and disseminating data on JCSG and PSI structures.
Krishna SS, Weekes D, Bakolitsa C, Elsliger MA, Wilson IA, Godzik A, Wooley J
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944203)
Times cited: 31
- The JCSG high-throughput structural biology pipeline.
Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wooley J, Wüthrich K, Wilson IA
JCSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 20944202)
Times cited: 74
- Structural bases of PAS doMAin-regulated kinase (PASK) activation in the absence of activation loop phosphorylation.
Kikani CK, Antonysamy SA, Bonanno JB, Romero R, Zhang FF, Russell M, Gheyi T, Iizuka M, Emtage S, Sauder JM, Turk BE, Burley SK, Rutter J
NYSGXRC, Journal of Biological Chemistry
(Details)(Pubmed ID: 20943661)
PDB ID(s): 3DLS
Times cited: 16
- Structural and functional insights into core ABA signaling.
Weiner JJ, Peterson FC, VolkMAn BF, Cutler SR
CESG, Current Opinion in Plant Biology
(Details)(Pubmed ID: 20934900)
Times cited: 94
- Structures of the CXCR4 chemokine GPCR with sMAll-molecule and cyclic peptide antagonists.
Wu B, Chien EY, Mol CD, Fenalti G, Liu W, Katritch V, Abagyan R, Brooun A, Wells P, Bi FC, Hamel DJ, Kuhn P, Handel TM, Cherezov V, Stevens RC
ATCG3D+CHSAM+GPCR, Science
(Details)(Pubmed ID: 20929726)
PDB ID(s): 3OE0 3OE6 3OE8 3OE9 3ODU
Times cited: 1125
- High-resolution structure of the nitrile reductase QueF combined with molecular simulations provide insight into enzyme mechanism.
Kim Y, Zhou M, Moy S, Morales J, Cunningham MA, Joachimiak A
MCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 20875425)
PDB ID(s): 3BP1
Times cited: 24
- Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids.
Xu Q, Eguchi T, MAthews II, Rife CL, Chiu HJ, Farr CL, Feuerhelm J, Jaroszewski L, Klock HE, Knuth MW, Miller MD, Weekes D, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 20869368)
PDB ID(s): 3OZ2
Times cited: 17
- Auto-induction medium containing glyphosate for high-level incorporation of unusual aroMAtic amino acids into proteins.
Neerathilingam M, MArkley JL
CESG, BioTechniques
(Details)(Pubmed ID: 20854268)
Times cited: 4
- Crystallographic and nuclear MAgnetic resonance evaluation of the impact of peptide binding to the second PDZ doMAin of protein tyrosine phosphatase 1E.
Zhang J, Sapienza PJ, Ke H, Chang A, Hengel SR, Wang H, Phillips GN, Lee AL
CESG, Biochemistry
(Details)(Pubmed ID: 20839809)
Times cited: 39
- The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal doMAin of huMAn Sufu.
Das D, Finn RD, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Cai X, Carlton D, Chen C, Chiu HJ, Chiu M, Clayton T, Deller MC, Duan L, Ellrott K, Farr CL, Feuerhelm J, Grant JC, Grzechnik A, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, KuMAr A, Lam WW, MArciano D, Miller MD, Morse AT, Nigoghossian E, Nopakun A, Okach L, Puckett C, Reyes R, Tien HJ, Trame CB, van den Bedem H, Weekes D, Wooten T, Xu Q, Yeh A, Zhou J, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Protein Science
(Details)(Pubmed ID: 20836087)
PDB ID(s): 3K5J
Times cited: 4
- Unmet challenges of structural genomics.
Chruszcz M, DoMAgalski M, Osinski T, Wlodawer A, Minor W
CSGID+MCSG, Current Opinion in Structural Biology
(Details)(Pubmed ID: 20810277)
Times cited: 28
- Substrate and drug binding sites in LeuT.
Nyola A, Karpowich NK, Zhen J, MArden J, Reith ME, Wang DN
NYCOMPS, Current Opinion in Structural Biology
(Details)(Pubmed ID: 20739005)
Times cited: 25
- Structure of a putative BenF-like porin from Pseudomonas fluorescens Pf-5 at 2.6 A resolution.
SampathkuMAr P, Lu F, Zhao X, Li Z, Gilmore J, Bain K, Rutter ME, Gheyi T, Schwinn KD, Bonanno JB, Pieper U, Fajardo JE, Fiser A, Almo SC, Swaminathan S, Chance MR, Baker D, Atwell S, Thompson DA, Emtage JS, WasserMAn SR, Sali A, Sauder JM, Burley SK
NYSGXRC, Proteins
(Details)(Pubmed ID: 20737437)
PDB ID(s): 3JTY
Times cited: 10
- Fully autoMAted high-quality NMR structure determination of sMAll (2)H-enriched proteins.
Tang Y, Schneider WM, Shen Y, RaMAn S, Inouye M, Baker D, Roth MJ, Montelione GT
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 20734145)
Times cited: 10
- Structural basis for selective activation of ABA receptors.
Peterson FC, Burgie ES, Park SY, Jensen DR, Weiner JJ, BingMAn CA, Chang CE, Cutler SR, Phillips GN, VolkMAn BF
CESG, Nature Structural & Molecular Biology
(Details)(Pubmed ID: 20729860)
PDB ID(s): 3NJ1 3NJ0 3NJO
Times cited: 54
- A conserved doMAin in the coronavirus membrane protein tail is important for virus assembly.
Arndt AL, Larson BJ, Hogue BG
MPID, Journal of Virology
(Details)(Pubmed ID: 20719948)
Times cited: 17
- TOPSAN: a collaborative annotation environment for structural genomics.
Weekes D, Krishna SS, Bakolitsa C, Wilson IA, Godzik A, Wooley J
JCSG, BMC Bioinformatics
(Details)(Pubmed ID: 20716366)
Times cited: 13
- NMR Structure of the SARS-CoV Nonstructural Protein 7 in Solution at pH 6.5.
Johnson MA, Jaudzems K, Wüthrich K
JCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 20709084)
PDB ID(s): 2KYS
Times cited: 8
- Combining NMR and EPR methods for homodimer protein structure determination.
Yang Y, Ramelot TA, McCarrick RM, Ni S, FeldMAnn EA, Cort JR, Wang H, Ciccosanti C, Jiang M, Janjua H, Acton TB, Xiao R, Everett JK, Montelione GT, Kennedy MA
NESG, Journal of the American Chemical Society
(Details)(Pubmed ID: 20698532)
Times cited: 25
- Crystal structures of Phd-Doc, HigA, and YeeU establish multiple evolutionary links between microbial growth-regulating toxin-antitoxin systems.
Arbing MA, HandelMAn SK, Kuzin AP, Verdon G, Wang C, Su M, Rothenbacher FP, Abashidze M, Liu M, Hurley JM, Xiao R, Acton T, Inouye M, Montelione GT, Woychik NA, Hunt JF
NESG, Structure
(Details)(Pubmed ID: 20696400)
Times cited: 42
- Structural Insight into the Mechanism of c-di-GMP Hydrolysis by EAL DoMAin Phosphodiesterases.
Tchigvintsev A, Xu X, Singer A, Chang C, Brown G, Proudfoot M, Cui H, Flick R, Anderson WF, Joachimiak A, Galperin MY, Savchenko A, Yakunin AF
MCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 20691189)
PDB ID(s): 2R6O
Times cited: 61
- The New York Consortium on Membrane Protein Structure (NYCOMPS): a high-throughput platform for structural genomics of integral membrane proteins.
Love J, MAncia F, Shapiro L, Punta M, Rost B, Girvin M, Wang DN, Zhou M, Hunt JF, Szyperski T, Gouaux E, MAcKinnon R, McDermott A, Honig B, Inouye M, Montelione G, Hendrickson WA
NESG+NYCOMPS, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 20690043)
Times cited: 29
- The high-throughput protein sample production platform of the Northeast Structural Genomics Consortium.
Xiao R, Anderson S, Aramini J, Belote R, Buchwald WA, Ciccosanti C, Conover K, Everett JK, Hamilton K, Huang YJ, Janjua H, Jiang M, Kornhaber GJ, Lee DY, Locke JY, MA LC, MAglaqui M, MAo L, Mitra S, Patel D, Rossi P, Sahdev S, SharMA S, Shastry R, Swapna GV, Tong SN, Wang D, Wang H, Zhao L, Montelione GT, Acton TB
NESG, Journal of Structural Biology
(Details)(Pubmed ID: 20688167)
Times cited: 79
- Methyl esterase 1 (StMES1) is required for systemic acquired resistance in potato.
MAnosalva PM, Park SW, Forouhar F, Tong L, Fry WE, Klessig DF
NESG, Molecular plant-microbe interactions : MPMI
(Details)(Pubmed ID: 20687805)
Times cited: 35
- MAss spectrometry guided in situ proteolysis to obtain crystals for X-ray structure determination.
Gheyi T, Rodgers L, Romero R, Sauder JM, Burley SK
NYSGXRC, Journal of the American Society for Mass Spectrometry
(Details)(Pubmed ID: 20685133)
Times cited: 11
- PoxA, YjeK, and Elongation Factor P Coordinately Modulate Virulence and Drug Resistance in Salmonella enterica.
Navarre WW, Zou SB, Roy H, Xie JL, Savchenko A, Singer A, Edvokimova E, Prost LR, KuMAr R, Ibba M, Fang FC
CSGID, Molecular Cell
(Details)(Pubmed ID: 20670890)
PDB ID(s): 3G1Z
Times cited: 91
- Conserved binding mode of huMAn beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography.
Wacker D, Fenalti G, Brown MA, Katritch V, Abagyan R, Cherezov V, Stevens RC
ATCG3D+GPCR, Journal of the American Chemical Society
(Details)(Pubmed ID: 20669948)
PDB ID(s): 3NY8 3NY9 3NYA
Times cited: 214
- Recent progress in the structure determination of GPCRs, a membrane protein family with high potential as pharMAceutical targets.
Cherezov V, Abola E, Stevens RC
ATCG3D, Methods in Molecular Biology
(Details)(Pubmed ID: 20665265)
Times cited: 38
- Solution NMR structure of Lin0431 protein from Listeria innocua reveals high structural similarity with doMAin II of bacterial transcription antitermination protein NusG.
Tang Y, Xiao R, Ciccosanti C, Janjua H, Lee DY, Everett JK, Swapna GV, Acton TB, Rost B, Montelione GT
NESG, Proteins
(Details)(Pubmed ID: 20602357)
Times cited: 1
- Three-dimensional structure of the weakly associated protein homodimer SeR13 using RDCs and paraMAgnetic surface MApping.
Lee HW, Wylie G, Bansal S, Wang X, Barb AW, MAcnaughtan MA, Ertekin A, Montelione GT, Prestegard JH
NESG, Protein Science
(Details)(Pubmed ID: 20589905)
Times cited: 13
- NleG Type 3 effectors from enterohaemorrhagic Escherichia coli are U-Box E3 ubiquitin ligases.
Wu B, Skarina T, Yee A, Jobin MC, Dileo R, Semesi A, Fares C, LeMAk A, Coombes BK, Arrowsmith CH, Singer AU, Savchenko A
NESG, PLos Pathogens
(Details)(Pubmed ID: 20585566)
Times cited: 50
- Identification of eukaryotic and prokaryotic methylthiotransferase for biosynthesis of 2-methylthio-N6-threonylcarbamoyladenosine in tRNA.
Arragain S, HandelMAn SK, Forouhar F, Wei FY, Tomizawa K, Hunt JF, Douki T, Fontecave M, Mulliez E, Atta M
NESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 20584901)
Times cited: 65
- Novel {alpha}-glucosidase from huMAn gut microbiome: substrate specificities and their switch.
Tan K, Tesar C, Wilton R, Keigher L, Babnigg G, Joachimiak A
MCSG, FASEB Journal
(Details)(Pubmed ID: 20581222)
PDB ID(s): 3N04 3M46 3M6D 3MKK
Times cited: 26
- Dead-end filling of SlipChip evaluated theoretically and experimentally as a function of the surface chemistry and the gap size between the plates for lubricated and dry SlipChips.
Li L, Karymov MA, Nichols KP, IsMAgilov RF
ATCG3D, Langmuir
(Details)(Pubmed ID: 20575548)
Times cited: 15
- Heme proteins--diversity in structural characteristics, function, and folding.
Smith LJ, KahraMAn A, Thornton JM
MCSG, Proteins
(Details)(Pubmed ID: 20544970)
Times cited: 74
- Expansion of the protein repertoire in newly explored environments: huMAn gut microbiome specific protein families.
Ellrott K, Jaroszewski L, Li W, Wooley JC, Godzik A
JCMM+JCSG, PLoS Computational Biology
(Details)(Pubmed ID: 20532204)
Times cited: 40
- To autoMAte or not to autoMAte: this is the question.
Cymborowski M, Klimecka M, Chruszcz M, ZimmerMAn MD, Shumilin IA, Borek D, Lazarski K, Joachimiak A, Otwinowski Z, Anderson W, Minor W
CSGID+MCSG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 20526815)
Times cited: 19
- New surface contacts formed upon reductive lysine methylation: improving the probability of protein crystallization.
Sledz P, Zheng H, Murzyn K, Chruszcz M, ZimmerMAn MD, Chordia MD, Joachimiak A, Minor W
MCSG, Protein Science
(Details)(Pubmed ID: 20506323)
Times cited: 24
- SARS coronavirus unique doMAin: three-doMAin molecular architecture in solution and RNA binding.
Johnson MA, Chatterjee A, NeuMAn BW, Wüthrich K
JCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 20493876)
PDB ID(s): 2KAF 2KQV 2KQW
Times cited: 18
- Role of the membrane localization doMAin of the Pseudomonas aeruginosa effector protein ExoU in cytotoxicity.
Veesenmeyer JL, Howell H, Halavaty AS, Ahrens S, Anderson WF, Hauser AR
CSGID, Infection and immunity
(Details)(Pubmed ID: 20479080)
Times cited: 22
- A plug-based microfluidic system for dispensing lipidic cubic phase (LCP) MAterial validated by crystallizing membrane proteins in lipidic mesophases
Li L, Fu Q, Kors CA, Stewart L, Nollert P, Laible PD, IsMAgilov RF
ATCG3D+SSGCID, Microfluidics and Nanofluidics
(Details)(Pubmed ID: 20473353)
Times cited: 20
- TM0486 from the hyperthermophilic anaerobe Thermotoga MAritiMA is a thiamin-binding protein involved in response of the cell to oxidative conditions.
Dermoun Z, Foulon A, Miller MD, Harrington DJ, Deacon AM, Sebban-Kreuzer C, Roche P, Lafitte D, Bornet O, Wilson IA, Dolla A
JCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 20471400)
PDB ID(s): 1VK8
Times cited: 8
- Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM doMAin.
Hom RA, Chang PY, Roy S, MusselMAn CA, Glass KC, Selezneva AI, Gozani O, IsMAgilov RF, Cleary ML, Kutateladze TG
ATCG3D, Journal of Molecular Biology
(Details)(Pubmed ID: 20460131)
PDB ID(s): 3MDF
Times cited: 26
- Computational design of a PAK1 binding protein.
Jha RK, Leaver-Fay A, Yin S, Wu Y, Butterfoss GL, Szyperski T, Dokholyan NV, KuhlMAn B
NESG, Journal of Molecular Biology
(Details)(Pubmed ID: 20460129)
Times cited: 51
- Cell-free synthesis and functional characterization of sphingolipid synthases from parasitic trypanosoMAtid protozoa.
Sevova ES, Goren MA, Schwartz KJ, Hsu FF, Turk J, Fox BG, Bangs JD
CESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 20457606)
Times cited: 24
- Solution NMR structure of the ARID doMAin of huMAn AT-rich interactive doMAin-containing protein 3A: a huMAn cancer protein interaction network target.
Liu G, Huang YJ, Xiao R, Wang D, Acton TB, Montelione GT
NESG, Proteins
(Details)(Pubmed ID: 20455271)
Times cited: 6
- LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment.
Liu W, Hanson MA, Stevens RC, Cherezov V
ATCG3D, Biophysical Journal
(Details)(Pubmed ID: 20409473)
Times cited: 38
- Structure of a virulence regulatory factor CvfB reveals a novel winged helix RNA binding module.
MAtsumoto Y, Xu Q, Miyazaki S, Kaito C, Farr CL, Axelrod HL, Chiu HJ, Klock HE, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Sekimizu K, Wilson IA
JCSG, Structure
(Details)(Pubmed ID: 20399190)
PDB ID(s): 3GO5
Times cited: 13
- High-throughput expression and purification of membrane proteins.
MAncia F, Love J
NYCOMPS, Journal of Structural Biology
(Details)(Pubmed ID: 20394823)
Times cited: 22
- High-throughput computational structure-based characterization of protein families: START doMAins and implications for structural genomics.
Lee H, Li Z, Silkov A, Fischer M, Petrey D, Honig B, Murray D
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 20383749)
Times cited: 8
- Structures of influenza A proteins and insights into antiviral drug targets.
Das K, Aramini JM, MA LC, Krug RM, Arnold E
NESG, Nature Structural & Molecular Biology
(Details)(Pubmed ID: 20383144)
Times cited: 201
- X-ray structure determination of the glycine cleavage system protein H of Mycobacterium tuberculosis using an inverse Compton synchrotron X-ray source.
Abendroth J, McCormick MS, Edwards TE, Staker B, Loewen R, Gifford M, Rifkin J, MAyer C, Guo W, Zhang Y, Myler P, Kelley A, Analau E, Hewitt SN, Napuli AJ, Kuhn P, Ruth RD, Stewart LJ
ATCG3D+SSGCID, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 20364333)
PDB ID(s): 3IFT
Times cited: 15
- An autoMAted pipeline to screen membrane protein 2D crystallization.
Kim C, Vink M, Hu M, Love J, Stokes DL, Ubarretxena-Belandia I
TEMIMPS, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 20349145)
Times cited: 11
- Structure and Protein-Protein Interaction Studies on Chlamydia trachoMAtis Protein CT670 (YscO homolog)
Lorenzini E, Singer A, Singh B, Lam R, Skarina T, Chirgadze NY, Savchenko A, Gupta RS
CSGID, Journal of Bacteriology
(Details)(Pubmed ID: 20348249)
PDB ID(s): 3K29
Times cited: 21
- Efficient condensed-phase production of perdeuterated soluble and membrane proteins.
Schneider WM, Tang Y, Vaiphei ST, MAo L, MAglaqui M, Inouye M, Roth MJ, Montelione GT
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 20333498)
Times cited: 12
- Structures of the autoproteolytic doMAin from the Saccharomyces cerevisiae nuclear pore complex component, Nup145
SampathkuMAr P, Ozyurt SA, Do J, Bain KT, Dickey M, Rodgers LA, Gheyi T, Sali A, Kim SJ, Phillips J, Pieper U, Fernandez-MArtinez J, Franke JD, MArtel A, Tsuruta H, Atwell S, Thompson DA, Emtage JS, WasserMAn SR, Rout MP, Sauder JM, Burley SK
NYSGXRC, Proteins
(Details)(Pubmed ID: 20310066)
PDB ID(s): 3KEP 3KES
Times cited: 9
- ArchScheMA: a tool for interactive graphing of related Pfam doMAin architectures.
Tamuri AU, Laskowski RA
MCSG, Bioinformatics
(Details)(Pubmed ID: 20299327)
Times cited: 16
- Crystal structure of an eIF4G-like protein from Danio rerio
Bae E, Bitto E, BingMAn CA, McCoy JG, Wesenberg GE, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 20229607)
PDB ID(s): 2I2O
Times cited: 2
- Cleavable C-terminal His-tag vectors for structure determination.
Eschenfeldt WH, MAltseva N, Stols L, Donnelly MI, Gu M, Nocek B, Tan K, Kim Y, Joachimiak A
CSGID+MCSG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 20213425)
Times cited: 24
- Structural basis of O6-alkylguanine recognition by a bacterial alkyltransferase-like DNA repair protein.
Aramini JM, Tubbs JL, Kanugula S, Rossi P, Ertekin A, MAglaqui M, Hamilton K, Ciccosanti CT, Jiang M, Xiao R, Soong TT, Rost B, Acton TB, Everett JK, Pegg AE, Tainer JA, Montelione GT
NESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 20212037)
Times cited: 14
- Cell-free protein synthesis technology in NMR high-throughput structure determination.
MAkino S, Goren MA, Fox BG, MArkley JL
CESG, Methods in Molecular Biology
(Details)(Pubmed ID: 20204854)
Times cited: 32
- AutoMAted electron microscopy for evaluating two-dimensional crystallization of membrane proteins.
Hu M, Vink M, Kim C, Derr K, Koss J, D'Amico K, Cheng A, Pulokas J, Ubarretxena-Belandia I, Stokes D
TEMIMPS, Journal of Structural Biology
(Details)(Pubmed ID: 20197095)
Times cited: 23
- Visualization of MAcromolecular structures.
O'Donoghue SI, Goodsell DS, Frangakis AS, Jossinet F, Laskowski RA, Nilges M, Saibil HR, Schafferhans A, Wade RC, Westhof E, Olson AJ
MCSG, Nature Methods
(Details)(Pubmed ID: 20195256)
Times cited: 67
- Protein crystallization using microfluidic technologies based on valves, droplets, and SlipChip.
Li L, IsMAgilov RF
ATCG3D, Annual review of biophysics
(Details)(Pubmed ID: 20192773)
Times cited: 111
- 'Hot' MAcromolecular crystals.
Koclega KD, Chruszcz M, ZimmerMAn MD, Bujacz G, Minor W
MCSG, Crystal Growth & Design
(Details)(Pubmed ID: 20161694)
PDB ID(s): 2IH2 2IH3 2IH4
Times cited: 3
- Structures of PHR DoMAins from Mus musculus Phr1 (Mycbp2) Explain the Loss-of-Function Mutation (Gly1092 -> Glu) of the C. elegans Ortholog RPM-1
SampathkuMAr P, Ozyurt SA, Miller S, Bain KT, Rutter ME, Gheyi T, Abrams B, Wang Y, Atwell S, Luz JG, Thompson DA, WasserMAn SR, Emtage JS, Park EC, Rongo C, Jin Y, Klemke RL, Sauder JM, Burley SK
NYSGXRC, Journal of Molecular Biology
(Details)(Pubmed ID: 20156452)
PDB ID(s): 3GBW 3HWJ
Times cited: 2
- Screening the MAmMAlian extracellular proteome for regulators of embryonic huMAn stem cell pluripotency.
Gonzalez R, Jennings LL, Knuth M, Orth AP, Klock HE, Ou W, Feuerhelm J, Hull MV, KoeseMA E, Wang Y, Zhang J, Wu C, Cho CY, Su AI, Batalov S, Chen H, Johnson K, Laffitte B, Nguyen DG, Snyder EY, Schultz PG, Harris JL, Lesley SA
JCSG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 20133595)
Times cited: 55
- NMR structure determination for larger proteins using backbone-only data.
RaMAn S, Lange OF, Rossi P, Tyka M, Wang X, Aramini J, Liu G, Ramelot TA, Eletsky A, Szyperski T, Kennedy MA, Prestegard J, Montelione GT, Baker D
NESG, Science
(Details)(Pubmed ID: 20133520)
Times cited: 170
- Crystal Structure of the First Eubacterial Mre11 Nuclease Reveals Novel Features that MAy Discriminate Substrates During DNA Repair.
Das D, Moiani D, Axelrod HL, Miller MD, McMullan D, Jin KK, Abdubek P, Astakhova T, Burra P, Carlton D, Chiu HJ, Clayton T, Deller MC, Duan L, Ernst D, Feuerhelm J, Grant JC, Grzechnik A, Grzechnik SK, Han GW, Jaroszewski L, Klock HE, Knuth MW, Kozbial P, Krishna SS, KuMAr A, MArciano D, Morse AT, Nigoghossian E, Okach L, Paulsen J, Reyes R, Rife CL, Sefcovic N, Tien HJ, Trame CB, van den Bedem H, Weekes D, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Tainer JA, Wilson IA
JCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 20122942)
PDB ID(s): 2Q8U
Times cited: 25
- A fast and autoMAted solution for accurately resolving protein doMAin architectures.
Yeats C, Redfern OC, Orengo C
MCSG, Bioinformatics
(Details)(Pubmed ID: 20118117)
Times cited: 22
- Structure-Based Discovery of Novel Chemotypes for Adenosine A(2A) Receptor Antagonists.
Katritch V, Jaakola VP, Lane JR, Lin J, IjzerMAn AP, Yeager M, Kufareva I, Stevens RC, Abagyan R
ATCG3D, Journal of Medicinal Chemistry
(Details)(Pubmed ID: 20095623)
Times cited: 164
- The hunt for 8-oxoguanine deaminase.
Hall RS, Fedorov AA, MArti-Arbona R, Fedorov EV, Kolb P, Sauder JM, Burley SK, Shoichet BK, Almo SC, Raushel FM
NYSGXRC, Accounts of Chemical Research
(Details)(Pubmed ID: 20088583)
PDB ID(s): 3H4U
Times cited: 24
- Protein secondary structure appears to be robust under in silico evolution while protein disorder appears not to be.
Schaefer C, Schlessinger A, Rost B
NESG, Bioinformatics
(Details)(Pubmed ID: 20081223)
Times cited: 36
- NMR structure of F-actin-binding doMAin of Arg/Abl2 from Homo sapiens.
Liu G, Huang YJ, Xiao R, Wang D, Acton TB, Montelione GT
NESG, Proteins
(Details)(Pubmed ID: 20077570)
PDB ID(s): 2KK1
Times cited: 3
- Genomics, evolution, and crystal structure of a new family of bacterial spore kinases.
Scheeff ED, Axelrod HL, Miller MD, Chiu HJ, Deacon AM, Wilson IA, MAnning G
JCSG, Proteins
(Details)(Pubmed ID: 20077512)
PDB ID(s): 2Q83
Times cited: 8
- Rapid, robotic, sMAll-scale protein production for NMR screening and structure determination.
Jensen DR, Woytovich C, Li M, Duvnjak P, Cassidy MS, Frederick RO, BergeMAn LF, Peterson FC, VolkMAn BF
CESG, Protein Science
(Details)(Pubmed ID: 20073081)
PDB ID(s): 2KOM
Times cited: 3
- Purification of transmembrane proteins from Saccharomyces cerevisiae for X-ray crystallography.
Clark KM, Fedoriw N, Robinson K, Connelly SM, Randles J, MAlkowski MG, DeTitta GT, Dumont ME
CHTSB, Protein Expression and Purification
(Details)(Pubmed ID: 20045057)
Times cited: 24
- Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety.
Burgin AB, MAgnusson OT, Singh J, Witte P, Staker BL, Bjornsson JM, Thorsteinsdottir M, Hrafnsdottir S, Hagen T, Kiselyov AS, Stewart LJ, Gurney ME
ATCG3D, Nature Biotechnology
(Details)(Pubmed ID: 20037581)
PDB ID(s): 3G58 3G4G 3G45 3G4I 3G4K 3G4L 3IAD
Times cited: 221
- MApping of ligand-binding cavities in proteins.
Andersson CD, Chen BY, Linusson A
NESG, Proteins
(Details)(Pubmed ID: 20034113)
Times cited: 22
- Nonlinear optical iMAging of integral membrane protein crystals in lipidic mesophases.
Kissick DJ, Gualtieri EJ, Simpson GJ, Cherezov V
ATCG3D, Analytical Chemistry
(Details)(Pubmed ID: 20025250)
Times cited: 47
- Structure and mechanism of a pentameric forMAte channel.
Waight AB, Love J, Wang DN
NYCOMPS, Nature Structural & Molecular Biology
(Details)(Pubmed ID: 20010838)
PDB ID(s): 3KLY 3KLZ
Times cited: 53
- Extra-cytoplasmic PAS-like DoMAins are Common In Signal Transduction Proteins.
Chang C, Tesar C, Gu M, Babnigg G, Joachimiak A, Pokkuluri PR, SzurMAnt H, Schiffer M
MCSG, Journal of Bacteriology
(Details)(Pubmed ID: 20008068)
PDB ID(s): 3CWF
Times cited: 26
- Post-translational modification of ribosoMAl proteins: structural and functional characterization of RimO from Thermotoga MAritiMA, a radical S-adenosylmethionine methylthiotransferase.
Arragain S, Garcia-Serres R, Blondin G, Douki T, CleMAncey M, Latour JM, Forouhar F, Neely H, Montelione GT, Hunt JF, Mulliez E, Fontecave M, Atta M
NESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 20007320)
PDB ID(s): 1OCT 2FB2 1K3R 1UWV
Times cited: 44
- Multiparameter screening on SlipChip used for nanoliter protein crystallization combining free interface diffusion and microbatch methods.
Li L, Du W, IsMAgilov RF
ATCG3D, Journal of the American Chemical Society
(Details)(Pubmed ID: 20000709)
PDB ID(s): 3II9
Times cited: 61
- User-loaded SlipChip for equipment-free multiplexed nanoliter-scale experiments.
Li L, Du W, IsMAgilov R
ATCG3D, Journal of the American Chemical Society
(Details)(Pubmed ID: 20000708)
PDB ID(s): 3KJR
Times cited: 37
- Accurate autoMAted protein NMR structure determination using unassigned NOESY data.
RaMAn S, Huang YJ, MAo B, Rossi P, Aramini JM, Liu G, Montelione GT, Baker D
NESG, Journal of the American Chemical Society
(Details)(Pubmed ID: 20000319)
Times cited: 35
- Crystal structure and molecular modeling study of N-carbamoylsarcosine amidase Ta0454 from ThermoplasMA acidophilum.
Luo HB, Zheng H, ZimmerMAn MD, Chruszcz M, Skarina T, Egorova O, Savchenko A, Edwards AM, Minor W
MCSG, Journal of Structural Biology
(Details)(Pubmed ID: 19932181)
PDB ID(s): 3EEF
Times cited: 12
- On the diversity of physicochemical environments experienced by identical ligands in binding pockets of unrelated proteins.
KahraMAn A, Morris RJ, Laskowski RA, Favia AD, Thornton JM
MCSG, Proteins
(Details)(Pubmed ID: 19927322)
Times cited: 35
- Solution NMR structures of proteins VPA0419 from Vibrio parahaemolyticus and yiiS from Shigella flexneri provide structural coverage for protein doMAin family PFAM 04175.
Singarapu KK, Mills JL, Xiao R, Acton T, Punta M, Fischer M, Honig B, Rost B, Montelione GT, Szyperski T
NESG, Proteins
(Details)(Pubmed ID: 19927321)
PDB ID(s): 2K3I 2JZ5
Times cited: 0
- GeMMA: functional subfamily classification within superfamilies of predicted protein structural doMAins.
Lee DA, Rentzsch R, Orengo C
MCSG, Nucleic Acids Research
(Details)(Pubmed ID: 19923231)
Times cited: 31
- Bacterial Pleckstrin Homology DoMAins: A Prokaryotic Origin for the PH DoMAin.
Xu Q, BateMAn A, Finn RD, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Carlton D, Chen C, Chiu HJ, Chiu M, Clayton T, Das D, Deller MC, Duan L, Ellrott K, Ernst D, Farr CL, Feuerhelm J, Grant JC, Grzechnik A, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, KuMAr A, MArciano D, McMullan D, Miller MD, Morse AT, Nigoghossian E, Nopakun A, Okach L, Puckett C, Reyes R, Rife CL, Sefcovic N, Tien HJ, Trame CB, van den Bedem H, Weekes D, Wooten T, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 19913036)
PDB ID(s): 3DCX 3HSA 3B77
Times cited: 17
- Protein Structure Initiative MAterial Repository: an open shared public resource of structural genomics plasmids for the biological community.
Cormier CY, Mohr SE, Zuo D, Hu Y, Rolfs A, Kramer J, Taycher E, Kelley F, Fiacco M, Turnbull G, LaBaer J
PSIMR, Nucleic Acids Research
(Details)(Pubmed ID: 19906724)
Times cited: 31
- The E. coli single protein production system for production and structural analysis of membrane proteins.
MAo L, Vaiphei ST, ShiMAzu T, Schneider WM, Tang Y, MAni R, Roth MJ, Montelione GT, Inouye M
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 19830594)
Times cited: 8
- Structural studies on cytosolic doMAin of MAgnesium transporter MgtE from Enterococcus faecalis.
RaguMAni S, Sauder JM, Burley SK, Swaminathan S
NYSGXRC, Proteins
(Details)(Pubmed ID: 19787770)
PDB ID(s): 2OUX
Times cited: 3
- MAking, breaking and sensing of cyclic di-GMP: Structural aspects
Kim D, Hunt JF, Schirmer T
NESG, The Second Messenger Cyclic Diguanylate
(Details)
PDB ID(s): 3IGN 2RDE 2V0N 1W25
Times cited: 0
2009
- X-Ray Diffraction Experiment: The Last Experiment in the Structure Elucidation Process
Chruszcz M, Borek D, DoMAgalski M, Otwinowski Z, Minor W
CSGID+MCSG, Advances in Protein Chemistry and Structural Biology
(Details)(Pubmed ID: 20663480)
Times cited: 6
- The structure of pyogenecin immunity protein, a novel bacteriocin-like immunity protein from Streptococcus pyogenes.
Chang C, Coggill P, BateMAn A, Finn RD, Cymborowski M, Otwinowski Z, Minor W, Volkart L, Joachimiak A
MCSG, BMC Structural Biology
(Details)(Pubmed ID: 20017931)
PDB ID(s): 2FU2
Times cited: 4
- Characterization of a Bacillus subtilis transporter for petrobactin, an anthrax stealth siderophore.
Zawadzka AM, Kim Y, MAltseva N, Nichiporuk R, Fan Y, Joachimiak A, Raymond KN
MCSG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 19955416)
PDB ID(s): 3GFV
Times cited: 47
- Cell-free translation of integral membrane proteins into unilamelar liposomes.
Goren MA, Nozawa A, MAkino S, Wrobel RL, Fox BG
CESG, Methods in Enzymology
(Details)(Pubmed ID: 19892197)
Times cited: 29
- (1)H, (13)C, and (15)N NMR assignments for the Bacillus subtilis yndB START doMAin.
Mercier KA, Mueller GA, Acton TB, Xiao R, Montelione GT, Powers R
NESG, Biomolecular NMR Assignments
(Details)(Pubmed ID: 19888688)
PDB ID(s): 2KEW
Times cited: 4
- Computation-Facilitated Assignment of the Function in the Enolase Superfamily: A Regiochemically Distinct Galactarate Dehydratase from Oceanobacillus iheyensis .
Rakus JF, KalyanaraMAn C, Fedorov AA, Fedorov EV, Mills-Groninger FP, Toro R, Bonanno J, Bain K, Sauder JM, Burley SK, Almo SC, Jacobson MP, Gerlt JA
NYSGXRC, Biochemistry
(Details)(Pubmed ID: 19883118)
PDB ID(s): 2OQY
Times cited: 25
- Simultaneous prediction of protein folding and docking at high resolution.
Das R, André I, Shen Y, Wu Y, LeMAk A, Bansal S, Arrowsmith CH, Szyperski T, Baker D
NESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 19864631)
Times cited: 102
- Structural genomics target selection for the New York consortium on membrane protein structure.
Punta M, Love J, HandelMAn S, Hunt JF, Shapiro L, Hendrickson WA, Rost B
NYCOMPS, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 19859826)
Times cited: 27
- Periplasmic doMAins of Pseudomonas aeruginosa PilN and PilO form a stable heterodimeric complex.
Sampaleanu LM, Bonanno JB, Ayers M, Koo J, TamMAm S, Burley SK, Almo SC, Burrows LL, Howell PL
NYSGXRC, Journal of Molecular Biology
(Details)(Pubmed ID: 19857646)
PDB ID(s): 2RJZ
Times cited: 54
- Production of membrane proteins for NMR studies using the condensed single protein (cSPP) production system.
MAo L, Tang Y, Vaiphei ST, ShiMAzu T, Kim SG, MAni R, Fakhoury E, White E, Montelione GT, Inouye M
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 19856129)
Times cited: 19
- The MAnnitol Operon Repressor MtlR Belongs to a New Class of Transcription Regulators in Bacteria.
Tan K, Borovilos M, Zhou M, Horer S, Clancy S, Moy S, Volkart LL, Sassoon J, BauMAnn U, Joachimiak A
MCSG, Journal of Biological Chemistry
(Details)(Pubmed ID: 19840941)
PDB ID(s): 3BRJ 3C8G
Times cited: 9
- Nuclear MAgnetic resonance structure of the nucleic acid-binding doMAin of severe acute respiratory syndrome coronavirus nonstructural protein 3.
Serrano P, Johnson MA, Chatterjee A, NeuMAn BW, Joseph JS, Buchmeier MJ, Kuhn P, Wüthrich K
JCSG, Journal of Virology
(Details)(Pubmed ID: 19828617)
PDB ID(s): 2K87
Times cited: 15
- The crystal structure of the AF2331 protein from Archaeoglobus fulgidus DSM 4304 forms an unusual interdigitated dimer with a new type of alpha + beta fold.
Wang S, Kirillova O, Chruszcz M, Gront D, ZimmerMAn MD, Cymborowski MT, Shumilin IA, Skarina T, Gorodichtchenskaia E, Savchenko A, Edwards AM, Minor W
MCSG, Protein Science
(Details)(Pubmed ID: 19768810)
PDB ID(s): 2FDO
Times cited: 2
- Three-dimensional structural view of the central metabolic network of Thermotoga MAritiMA.
Zhang Y, Thiele I, Weekes D, Li Z, Jaroszewski L, Ginalski K, Deacon AM, Wooley J, Lesley SA, Wilson IA, Palsson B, OsterMAn A, Godzik A
JCMM+JCSG, Science
(Details)(Pubmed ID: 19762644)
Times cited: 110
- Correlating protein function and stability through the analysis of single amino acid substitutions.
Bromberg Y, Rost B
NESG, BMC Bioinformatics
(Details)(Pubmed ID: 19758472)
Times cited: 25
- CASD-NMR: critical assessment of autoMAted structure determination by NMR.
Rosato A, Bagaria A, Baker D, Bardiaux B, Cavalli A, Doreleijers JF, Giachetti A, Guerry P, Güntert P, HerrMAnn T, Huang YJ, Jonker HR, MAo B, MAlliavin TE, Montelione GT, Nilges M, RaMAn S, van der Schot G, Vranken WF, Vuister GW, Bonvin AM
NESG, Nature Methods
(Details)(Pubmed ID: 19718014)
Times cited: 42
- FLORA: a novel method to predict protein function from structure in diverse superfamilies.
Redfern OC, Dessailly BH, DallMAn TJ, Sillitoe I, Orengo CA
MCSG, PLoS Computational Biology
(Details)(Pubmed ID: 19714201)
Times cited: 31
- Heterologous expression of L. MAjor proteins in S. cerevisiae: a test of solubility, purity, and gene recoding.
Quartley E, Alexandrov A, Mikucki M, Buckner FS, Hol WG, DeTitta GT, Phizicky EM, Grayhack EJ
CHTSB, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 19701618)
Times cited: 32
- The CATH hierarchy revisited-structural divergence in doMAin superfamilies and the continuity of fold space.
Cuff A, Redfern OC, Greene L, Sillitoe I, Lewis T, Dibley M, Reid A, Pearl F, DallMAn T, Todd A, Garratt R, Thornton J, Orengo C
MCSG, Structure
(Details)(Pubmed ID: 19679085)
Times cited: 32
- Structure of a microsporidian methionine aminopeptidase type 2 complexed with fuMAgillin and TNP-470.
Alvarado JJ, Nemkal A, Sauder JM, Russell M, Akiyoshi DE, Shi W, Almo SC, Weiss LM
NYSGXRC, Molecular and Biochemical Parasitology
(Details)(Pubmed ID: 19660503)
PDB ID(s): 3FM3 3FMQ 3FMR
Times cited: 14
- Structure and electrostatic property of cytoplasmic doMAin of ZntB transporter.
Tan K, Sather A, Robertson JL, Moy S, Roux B, Joachimiak A
MCSG, Protein Science
(Details)(Pubmed ID: 19653298)
PDB ID(s): 3CK6
Times cited: 10
- SlipChip.
Du W, Li L, Nichols KP, IsMAgilov RF
ATCG3D, Lab on a Chip
(Details)(Pubmed ID: 19636458)
Times cited: 189
- Applications of bioinforMAtics to protein structures: how protein structure and bioinforMAtics overlap.
Han GW, Rife C, Sawaya MR
JCSG, Methods in Molecular Biology
(Details)(Pubmed ID: 19623490)
Times cited: 0
- Structural and molecular mechanism for autoprocessing of MARTX Toxin of Vibrio cholerae at multiple sites.
Prochazkova K, Shuvalova LA, Minasov G, Voburka Z, Anderson WF, Satchell KJ
CSGID, Journal of Biological Chemistry
(Details)(Pubmed ID: 19620709)
PDB ID(s): 3FZY
Times cited: 50
- Benefits of structural genomics for drug discovery research.
Grabowski M, Chruszcz M, ZimmerMAn MD, Kirillova O, Minor W
CSGID+MCSG, Infectious disorders drug targets
(Details)(Pubmed ID: 19594422)
Times cited: 23
- Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes.
Xu Q, Traag BA, Willemse J, McMullan D, Miller MD, Elsliger MA, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Carlton D, Chen C, Chiu HJ, Chruszcz M, Clayton T, Das D, Deller MC, Duan L, Ellrott K, Ernst D, Farr CL, Feuerhelm J, Grant JC, Grzechnik A, Grzechnik SK, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, KuMAr A, MArciano D, Minor W, MomMAas AM, Morse AT, Nigoghossian E, Nopakun A, Okach L, OomMAchen S, Paulsen J, Puckett C, Reyes R, Rife CL, Sefcovic N, Tien HJ, Trame CB, van den Bedem H, Wang S, Weekes D, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA, van Wezel GP
JCSG+MCSG, Journal of Biological Chemistry
(Details)(Pubmed ID: 19567872)
PDB ID(s): 3CM1
Times cited: 17
- Determination and application of empirically derived detergent phase boundaries to effectively crystallize membrane proteins.
Koszelak-Rosenblum M, Krol A, Mozumdar N, Wunsch K, Ferin A, Cook E, Veatch CK, Nagel R, Luft JR, Detitta GT, MAlkowski MG
CHTSB, Protein Science
(Details)(Pubmed ID: 19554626)
Times cited: 26
- ADP-dependent 6-Phosphofructokinase from Pyrococcus horikoshii OT3: STRUCTURE DETERMINATION AND BIOCHEMICAL CHARACTERIZATION OF PH1645.
Currie MA, Merino F, Skarina T, Wong AH, Singer A, Brown G, Savchenko A, Caniuguir A, Guixé V, Yakunin AF, Jia Z
MCSG, Journal of Biological Chemistry
(Details)(Pubmed ID: 19553681)
PDB ID(s): 3DRW
Times cited: 14
- Rastering strategy for screening and centring of microcrystal samples of huMAn membrane proteins with a sub-10 microm size X-ray synchrotron beam.
Cherezov V, Hanson MA, Griffith MT, Hilgart MC, Sanishvili R, Nagarajan V, Stepanov S, Fischetti RF, Kuhn P, Stevens RC
ATCG3D, Journal of the Royal Society, Interface / the Royal Society
(Details)(Pubmed ID: 19535414)
Times cited: 103
- PSI-2: structural genomics to cover protein doMAin family space.
Dessailly BH, Nair R, Jaroszewski L, Fajardo JE, Kouranov A, Lee D, Fiser A, Godzik A, Rost B, Orengo C
JCSG+NESG+MCSG, Structure
(Details)(Pubmed ID: 19523904)
Times cited: 89
- Spherical-harmonic decomposition for molecular recognition in electron-density MAps.
DiMAio FP, Soni AB, Phillips GN, Shavlik JW
CESG, International journal of data mining and bioinformatics
(Details)(Pubmed ID: 19517990)
Times cited: 4
- PINE-SPARKY: graphical interface for evaluating autoMAted probabilistic peak assignments in protein NMR spectroscopy.
Lee W, Westler WM, Bahrami A, Eghbalnia HR, MArkley JL
CESG, Bioinformatics
(Details)(Pubmed ID: 19497931)
Times cited: 54
- Oxidase activity of a flavin-dependent thymidylate synthase.
Wang Z, Chernyshev A, Koehn EM, MAnuel TD, Lesley SA, Kohen A
JCSG, FEBS Journal
(Details)(Pubmed ID: 19459936)
PDB ID(s): 1024 1025 1026 1027 1028 102B 1029 102A 1KQ4
Times cited: 12
- NMR structure of protein YvyC from Bacillus subtilis reveals unexpected structural similarity between two PFAM families.
Eletsky A, SukuMAran DK, Xiao R, Acton TB, Rost B, Montelione GT, Szyperski T
NESG, Proteins
(Details)(Pubmed ID: 19455708)
PDB ID(s): 2HC5
Times cited: 0
- Crystal structure of histidine phosphotransfer protein ShpA, an essential regulator of stalk biogenesis in Caulobacter crescentus.
Xu Q, Carlton D, Miller MD, Elsliger MA, Krishna SS, Abdubek P, Astakhova T, Burra P, Chiu HJ, Clayton T, Deller MC, Duan L, Elias Y, Feuerhelm J, Grant JC, Grzechnik A, Grzechnik SK, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, KuMAr A, MArciano D, McMullan D, Morse AT, Nigoghossian E, Okach L, OomMAchen S, Paulsen J, Reyes R, Rife CL, Sefcovic N, Trame C, Trout CV, van den Bedem H, Weekes D, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 19450606)
PDB ID(s): 2OOC
Times cited: 8
- Empirical correlation between protein backbone 15N and 13C secondary chemical shifts and its application to nitrogen chemical shift re-referencing.
Wang L, MArkley JL
CESG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 19436955)
Times cited: 17
- Mixing and MAtching detergents for membrane protein NMR structure determination.
Columbus L, Lipfert J, Jambunathan K, Fox DA, Sim AY, Doniach S, Lesley SA
JCSG, Journal of the American Chemical Society
(Details)(Pubmed ID: 19425578)
Times cited: 64
- Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins.
Park SY, Fung P, Nishimura N, Jensen DR, Fujii H, Zhao Y, Lumba S, Santiago J, Rodrigues A, Chow TF, Alfred SE, Bonetta D, Finkelstein R, Provart NJ, Desveaux D, Rodriguez PL, McCourt P, Zhu JK, Schroeder JI, VolkMAn BF, Cutler SR
CESG, Science
(Details)(Pubmed ID: 19407142)
Times cited: 1121
- Exploiting structural classifications for function prediction: towards a doMAin gramMAr for protein function.
Dessailly BH, Redfern OC, Cuff A, Orengo CA
MCSG, Current Opinion in Structural Biology
(Details)(Pubmed ID: 19398323)
Times cited: 24
- An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene.
Koehn EM, FleischMAnn T, Conrad JA, Palfey BA, Lesley SA, MAthews II, Kohen A
JCSG, Nature
(Details)(Pubmed ID: 19370033)
PDB ID(s): 1O24 1O25 1O26 1O27 1O28 1O2B 1029 1O2A 1KQ4
Times cited: 53
- Metal-MACiE: a database of metals involved in biological catalysis.
Andreini C, Bertini I, Cavallaro G, Holliday GL, Thornton JM
MCSG, Bioinformatics
(Details)(Pubmed ID: 19369503)
Times cited: 37
- Functional Annotation of Two New Carboxypeptidases from the Amidohydrolase Superfamily of Enzymes.
Xiang DF, Xu C, KuMAran D, Brown AC, Sauder JM, Burley SK, Swaminathan S, Raushel FM
NYSGXRC, Biochemistry
(Details)(Pubmed ID: 19358546)
PDB ID(s): 2QS8
Times cited: 9
- Analysis of the varicella-zoster virus IE62 N-terminal acidic transactivating doMAin and its interaction with the huMAn mediator complex.
YaMAmoto S, Eletsky A, Szyperski T, Hay J, Ruyechan WT
NESG, Journal of Virology
(Details)(Pubmed ID: 19357160)
Times cited: 22
- Laterally mobile, functionalized self-assembled monolayers at the fluorous-aqueous interface in a plug-based microfluidic system: characterization and testing with membrane protein crystallization.
Kreutz JE, Li L, Roach LS, HatakeyaMA T, IsMAgilov RF
ATCG3D, Journal of the American Chemical Society
(Details)(Pubmed ID: 19354215)
Times cited: 41
- Structures of two Arabidopsis thaliana MAjor latex proteins represent novel helix-grip folds
Lytle BL, Song J, de la Cruz NB, Peterson FC, Johnson KA, BingMAn CA, Phillips GN, VolkMAn BF
CESG, Proteins
(Details)(Pubmed ID: 19326460)
PDB ID(s): 1VJH 2I9Y
Times cited: 30
- Structure of Thermotoga MAritiMA TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD doMAins.
Zheng M, Cooper DR, Grossoehme NE, Yu M, Hung LW, Cieslik M, Derewenda U, Lesley SA, Wilson IA, Giedroc DP, Derewenda ZS
JCSG, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 19307717)
PDB ID(s): 3FMS
Times cited: 11
- Construct optimization for protein NMR structure analysis using amide hydrogen/deuterium exchange MAss spectrometry.
SharMA S, Zheng H, Huang YJ, Ertekin A, Hamuro Y, Rossi P, Tejero R, Acton TB, Xiao R, Jiang M, Zhao L, MA LC, Swapna GV, Aramini JM, Montelione GT
NESG, Proteins
(Details)(Pubmed ID: 19306341)
Times cited: 25
- Unique opportunities for NMR methods in structural genomics.
Montelione GT, Arrowsmith C, Girvin ME, Kennedy MA, MArkley JL, Powers R, Prestegard JH, Szyperski T
CESG+NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 19288278)
Times cited: 13
- Probabilistic interaction network of evidence algorithm and its application to complete labeling of peak lists from protein NMR spectroscopy.
Bahrami A, Assadi AH, MArkley JL, Eghbalnia HR
CESG, PLoS Computational Biology
(Details)(Pubmed ID: 19282963)
Times cited: 115
- Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin.
LeiMAn PG, Basler M, RaMAgopal UA, Bonanno JB, Sauder JM, Pukatzki S, Burley SK, Almo SC, Mekalanos JJ
NYSGXRC, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 19251641)
PDB ID(s): 2P5Z
Times cited: 309
- Crystal Structures of YkuI and Its Complex with Second Messenger Cyclic Di-GMP Suggest Catalytic Mechanism of Phosphodiester Bond Cleavage by EAL DoMAins
Minasov G, Padavattan S, Shuvalova L, Brunzelle JS, Miller DJ, Baslé A, MAssa C, Collart FR, Schirmer T, Anderson WF
MCSG, Journal of Biological Chemistry
(Details)(Pubmed ID: 19244251)
PDB ID(s): 2BAS
Times cited: 58
- The structural basis of gas-responsive transcription by the huMAn nuclear hormone receptor REV-ERBbeta.
Pardee KI, Xu X, Reinking J, Schuetz A, Dong A, Liu S, Zhang R, Tiefenbach J, Lajoie G, Plotnikov AN, Botchkarev A, Krause HM, Edwards A
MCSG, PLoS Biology
(Details)(Pubmed ID: 19243223)
Times cited: 82
- X-ray structure of Danio rerio secretagogin: A hexa-EF-hand calcium sensor.
Bitto E, BingMAn CA, Bittova L, Frederick RO, Fox BG, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 19241471)
PDB ID(s): 2BE4
Times cited: 16
- Protein function annotation by homology-based inference.
Loewenstein Y, Raimondo D, Redfern OC, Watson J, FrishMAn D, Linial M, Orengo C, Thornton J, Tramontano A
MCSG, Genome Biology
(Details)(Pubmed ID: 19226439)
Times cited: 115
- Evolution of enzyMAtic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes.
Sakai A, Fedorov AA, Fedorov EV, Schnoes AM, Glasner ME, Brown S, Rutter ME, Bain K, Chang S, Gheyi T, Sauder JM, Burley SK, Babbitt PC, Almo SC, Gerlt JA
NYSGXRC, Biochemistry
(Details)(Pubmed ID: 19220063)
PDB ID(s): 3DG3 3DG6 3DG7 3DGB 3CT2
Times cited: 29
- Structural Basis of Murein Peptide Specificity of a gamMA-D-Glutamyl-L-Diamino Acid Endopeptidase.
Xu Q, Sudek S, McMullan D, Miller MD, Geierstanger B, Jones DH, Krishna SS, Spraggon G, Bursalay B, Abdubek P, Acosta C, Ambing E, Astakhova T, Axelrod HL, Carlton D, Caruthers J, Chiu HJ, Clayton T, Deller MC, Duan L, Elias Y, Elsliger MA, Feuerhelm J, Grzechnik SK, Hale J, Won Han G, Haugen J, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, KuMAr A, MArciano D, Morse AT, Nigoghossian E, Okach L, OomMAchen S, Paulsen J, Reyes R, Rife CL, Trout CV, van den Bedem H, Weekes D, White A, Wolf G, Zubieta C, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Structure
(Details)(Pubmed ID: 19217401)
PDB ID(s): 2HBW 2FG0 2EVR
Times cited: 43
- Outcome of a workshop on applications of protein models in biomedical research.
Schwede T, Sali A, Honig B, Levitt M, BerMAn HM, Jones D, Brenner SE, Burley SK, Das R, Dokholyan NV, Dunbrack RL, Fidelis K, Fiser A, Godzik A, Huang YJ, Humblet C, Jacobson MP, Joachimiak A, Krystek SR, Kortemme T, Kryshtafovych A, Montelione GT, Moult J, Murray D, Sanchez R, Sosnick TR, Standley DM, Stouch T, Vajda S, Vasquez M, Westbrook JD, Wilson IA
JCSG+MCSG+NESG+NMHRCM+NYSGXRC, Structure
(Details)(Pubmed ID: 19217386)
Times cited: 72
- Structural genomics reveals EVE as a new ASCH/PUA-related doMAin.
Bertonati C, Punta M, Fischer M, Yachdav G, Forouhar F, Zhou W, Kuzin AP, SeetharaMAn J, Abashidze M, Ramelot TA, Kennedy MA, Cort JR, Belachew A, Hunt JF, Tong L, Montelione GT, Rost B
NESG, Proteins
(Details)(Pubmed ID: 19191354)
Times cited: 14
- Crystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 A resolution.
Das D, Kozbial P, Axelrod HL, Miller MD, McMullan D, Krishna SS, Abdubek P, Acosta C, Astakhova T, Burra P, Carlton D, Chen C, Chiu HJ, Clayton T, Deller MC, Duan L, Elias Y, Elsliger MA, Ernst D, Farr C, Feuerhelm J, Grzechnik A, Grzechnik SK, Hale J, Han GW, Jaroszewski L, Jin KK, Johnson HA, Klock HE, Knuth MW, KuMAr A, MArciano D, Morse AT, Murphy KD, Nigoghossian E, Nopakun A, Okach L, OomMAchen S, Paulsen J, Puckett C, Reyes R, Rife CL, Sefcovic N, Sudek S, Tien H, Trame C, Trout CV, van den Bedem H, Weekes D, White A, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 19173316)
PDB ID(s): 3BY7
Times cited: 10
- The Thermotoga MAritiMA Trk potassium transporter--from frameshift to function.
Johnson HA, Hampton E, Lesley SA
JCSG, Journal of Bacteriology
(Details)(Pubmed ID: 19168617)
PDB ID(s): 2G1U
Times cited: 7
- Discovery of new GPCR biology: one receptor structure at a time.
Hanson MA, Stevens RC
ATCG3D, Structure
(Details)(Pubmed ID: 19141277)
Times cited: 148
- DoMAin-based and family-specific sequence identity thresholds increase the levels of reliable protein function transfer.
Addou S, Rentzsch R, Lee D, Orengo CA
MCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 19135455)
Times cited: 39
- The center for eukaryotic structural genomics.
MArkley JL, Aceti DJ, BingMAn CA, Fox BG, Frederick RO, MAkino S, Nichols KW, Phillips GN, Primm JG, Sahu SC, Vojtik FC, VolkMAn BF, Wrobel RL, Zolnai Z
CESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 19130299)
Times cited: 14
- Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 A resolution.
Das D, Krishna SS, McMullan D, Miller MD, Xu Q, Abdubek P, Acosta C, Astakhova T, Axelrod HL, Burra P, Carlton D, Chiu HJ, Clayton T, Deller MC, Duan L, Elias Y, Elsliger MA, Ernst D, Feuerhelm J, Grzechnik A, Grzechnik SK, Hale J, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, KuMAr A, MArciano D, Morse AT, Murphy KD, Nigoghossian E, Okach L, OomMAchen S, Paulsen J, Reyes R, Rife CL, Sefcovic N, Tien H, Trame CB, Trout CV, van den Bedem H, Weekes D, White A, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 19127588)
PDB ID(s): 3EQX
Times cited: 16
- NMR and X-RAY structures of huMAn E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1) reveal structural and functional conservation in the metazoan UFM1-UBA5-UFC1 ubiquination pathway.
Liu G, Forouhar F, Eletsky A, Atreya HS, Aramini JM, Xiao R, Huang YJ, Abashidze M, SeetharaMAn J, Liu J, Rost B, Acton T, Montelione GT, Hunt JF, Szyperski T
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 19101823)
Times cited: 9
- Hard X-ray phase-contrast iMAging with the Compact Light Source based on inverse Compton X-rays.
Bech M, Bunk O, David C, Ruth R, Rifkin J, Loewen R, Feidenhans'l R, Pfeiffer F
ATCG3D, Journal of Synchrotron Radiation
(Details)(Pubmed ID: 19096173)
Times cited: 90
- Crystal structure of a novel archaeal AAA+ ATPase SSO1545 from Sulfolobus solfataricus.
Xu Q, Rife CL, Carlton D, Miller MD, Krishna SS, Elsliger MA, Abdubek P, Astakhova T, Chiu HJ, Clayton T, Duan L, Feuerhelm J, Grzechnik SK, Hale J, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, KuMAr A, McMullan D, Morse AT, Nigoghossian E, Okach L, OomMAchen S, Paulsen J, Reyes R, van den Bedem H, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 19089981)
PDB ID(s): 2FNA
Times cited: 8
- Understanding the physical properties that control protein crystallization by analysis of large-scale experimental data.
Price Ii WN, Chen Y, HandelMAn SK, Neely H, MAnor P, Karlin R, Nair R, Liu J, Baran M, Everett J, Tong SN, Forouhar F, Swaminathan SS, Acton T, Xiao R, Luft JR, Lauricella A, Detitta GT, Rost B, Montelione GT, Hunt JF
CHTSB+NESG, Nature Biotechnology
(Details)(Pubmed ID: 19079241)
Times cited: 99
- Nuclear MAgnetic resonance structure shows that the severe acute respiratory syndrome coronavirus-unique doMAin contains a MAcrodoMAin fold.
Chatterjee A, Johnson MA, Serrano P, Pedrini B, Joseph JS, NeuMAn BW, Saikatendu K, Buchmeier MJ, Kuhn P, Wüthrich K
JCSG, Journal of Virology
(Details)(Pubmed ID: 19052085)
PDB ID(s): 2RNK 2JZD 2JZF 2JZE
Times cited: 22
- The Protein Model Portal.
Arnold K, Kiefer F, Kopp J, Battey JN, Podvinec M, Westbrook JD, BerMAn HM, Bordoli L, Schwede T
PSISBKB, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 19037750)
Times cited: 92
- The protein structure initiative structural genomics knowledgebase.
BerMAn HM, Westbrook JD, Gabanyi MJ, Tao W, Shah R, Kouranov A, Schwede T, Arnold K, Kiefer F, Bordoli L, Kopp J, Podvinec M, Adams PD, Carter LG, Minor W, Nair R, La Baer J
MCSG+PSISBKB, Nucleic Acids Research
(Details)(Pubmed ID: 19010965)
Times cited: 64
- Crystal structure of huMAn retinoblastoMA binding protein 9.
Vorobiev SM, Su M, SeetharaMAn J, Huang YJ, Chen CX, MAglaqui M, Janjua H, Proudfoot M, Yakunin A, Xiao R, Acton TB, Montelione GT, Tong L
NESG, Proteins
(Details)(Pubmed ID: 19004028)
PDB ID(s): 2QS9
Times cited: 7
- A structural basis for the regulatory inactivation of DnaA.
Xu Q, McMullan D, Abdubek P, Astakhova T, Carlton D, Chen C, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Elsliger MA, Feuerhelm J, Hale J, Han GW, Jaroszewski L, Jin KK, Johnson HA, Klock HE, Knuth MW, Kozbial P, Sri Krishna S, KuMAr A, MArciano D, Miller MD, Morse AT, Nigoghossian E, Nopakun A, Okach L, OomMAchen S, Paulsen J, Puckett C, Reyes R, Rife CL, Sefcovic N, Trame C, van den Bedem H, Weekes D, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 19000695)
PDB ID(s): 3BOS
Times cited: 12
- A Family of LIC Vectors for High-Throughput Cloning and Purification of Proteins.
Eschenfeldt WH, Lucy S, Millard CS, Joachimiak A, MArk ID
MCSG, Methods in Molecular Biology
(Details)(Pubmed ID: 18988021)
Times cited: 140
- Flexi vector cloning.
Blommel PG, MArtin PA, Seder KD, Wrobel RL, Fox BG
CESG, Methods in Molecular Biology
(Details)(Pubmed ID: 18988018)
Times cited: 18
- Improved scoring function for comparative modeling using the M4T method.
Rykunov D, Steinberger E, MAdrid-Aliste CJ, Fiser A
NYSGXRC, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 18985440)
Times cited: 22
- Structural elucidation of the Cys-His-Glu-Asn proteolytic relay in the secreted CHAP doMAin enzyme from the huMAn pathogen Staphylococcus saprophyticus.
Rossi P, Aramini JM, Xiao R, Chen CX, Nwosu C, Owens LA, MAglaqui M, Nair R, Fischer M, Acton TB, Honig B, Rost B, Montelione GT
NESG, Proteins
(Details)(Pubmed ID: 18951393)
PDB ID(s): 2K3A
Times cited: 19
- MODBASE, a database of annotated comparative protein structure models and associated resources.
Pieper U, Eswar N, Webb BM, Eramian D, Kelly L, Barkan DT, Carter H, MAnkoo P, Karchin R, MArti-Renom MA, Davis FP, Sali A
NYSGXRC, Nucleic Acids Research
(Details)(Pubmed ID: 18948282)
Times cited: 123
- Improving NMR protein structure quality by Rosetta refinement: A molecular replacement study.
Ramelot TA, RaMAn S, Kuzin AP, Xiao R, MA LC, Acton TB, Hunt JF, Montelione GT, Baker D, Kennedy MA
NESG, Proteins
(Details)(Pubmed ID: 18816799)
Times cited: 42
- Discovery of sarcosine dimethylglycine methyltransferase from Galdieria sulphuraria.
McCoy JG, Bailey LJ, Ng YH, BingMAn CA, Wrobel R, Weber AP, Fox BG, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 18623062)
PDB ID(s): 2O57
Times cited: 6
- Structural characterization of CalO2: A putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway.
McCoy JG, Johnson HD, Singh S, BingMAn CA, Lei IK, Thorson JS, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 18561189)
PDB ID(s): 3BUJ
Times cited: 20
- X-ray structure of ILL2, an auxin-conjugate amidohydrolase from Arabidopsis thaliana.
Bitto E, BingMAn CA, Bittova L, Houston NL, Boston RS, Fox BG, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 18543330)
PDB ID(s): 1XMB
Times cited: 26
- High PerforMAnce Computing in the Real World
Kunken JM
ATCG3D, Windows HPC Server 2008
(Details)
Times cited: 0
2008
- High-throughput protein purification for X-ray crystallography and NMR
Kim Y, Bigelow L, Borovilos M., Dementieva I., Duggan E., Eschenfeldt W., Hatzos C., Joachimiak G., Li H., MAltseva N., Mulligan R., Quartey P., Sather A., Stols L., Volkart L., Wu R., Zhou M., and Joachimiak A
CSGID, Advances in Protein Chemistry
(Details)(Pubmed ID: 20731990)
Times cited: 22
- Function-Biased Choice of Additives for Optimization of Protein Crystallization: The Case of the Putative Thioesterase PA5185 from Pseudomonas aeruginosa PAO1
Chruszcz M, ZimmerMAn MD, Wang SR, Koclega KD, Zheng H, Evdokimova E, Kudritska M, Cymborowski M, Savchenko A, Edwards A, Minor W
MCSG, Crystal Growth & Design
(Details)(Pubmed ID: 19898606)
PDB ID(s): 2AV9 2OU5 2O6B 2O6T 2O6U
Times cited: 3
- NMR assignment of the nonstructural protein nsp3(1066-1181) from SARS-CoV.
Serrano P, Johnson MA, Chatterjee A, Pedrini B, Wüthrich K
JCSG, Biomolecular NMR Assignments
(Details)(Pubmed ID: 19636888)
PDB ID(s): 2K87
Times cited: 2
- LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization.
Cherezov V, Liu J, Griffith M, Hanson MA, Stevens RC
ATCG3D, Crystal Growth & Design
(Details)(Pubmed ID: 19234616)
Times cited: 38
- Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis.
Artz JD, Dunford JE, Arrowood MJ, Dong A, Chruszcz M, Kavanagh KL, Minor W, Russell RG, Ebetino FH, OpperMAnn U, Hui R
MCSG, Chemistry & Biology
(Details)(Pubmed ID: 19101474)
Times cited: 29
- Molecular basis of Pirh2-mediated p53 ubiquitylation.
Sheng Y, Laister RC, LeMAk A, Wu B, Tai E, Duan S, Lukin J, Sunnerhagen M, Srisailam S, Karra M, Benchimol S, Arrowsmith CH
NESG, Nature Structural & Molecular Biology
(Details)(Pubmed ID: 19043414)
Times cited: 57
- Structure of the putative 32 kDa myrosinase-binding protein from Arabidopsis (At3g16450.1) determined by SAIL-NMR.
Takeda M, Sugimori N, Torizawa T, Terauchi T, Ono AM, Yagi H, YaMAguchi Y, Kato K, Ikeya T, Jee J, Güntert P, Aceti DJ, MArkley JL, Kainosho M
CESG, FEBS Journal
(Details)(Pubmed ID: 19021763)
PDB ID(s): 2JZ4
Times cited: 21
- Establishing a training set through the visual analysis of crystallization trials. Part II: crystal examples.
Snell EH, Lauricella AM, Potter SA, Luft JR, Gulde SM, Collins RJ, Franks G, MAlkowski MG, Cumbaa C, Jurisica I, DeTitta GT
CHTSB+NESG+SGPP, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 19020351)
Times cited: 13
- Establishing a training set through the visual analysis of crystallization trials. Part I: approxiMAtely 150,000 iMAges.
Snell EH, Luft JR, Potter SA, Lauricella AM, Gulde SM, MAlkowski MG, Koszelak-Rosenblum M, Said MI, Smith JL, Veatch CK, Collins RJ, Franks G, Thayer M, Cumbaa C, Jurisica I, Detitta GT
CHTSB, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 19020350)
Times cited: 18
- The application and use of chemical space MApping to interpret crystallization screening results.
Snell EH, Nagel RM, Wojtaszcyk A, O'Neill H, Wolfley JL, Luft JR
CHTSB, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 19018100)
Times cited: 20
- New paradigm for MAcromolecular crystallography experiments at SSRL: autoMAted crystal screening and remote data collection.
Soltis SM, Cohen AE, Deacon A, Eriksson T, González A, McPhillips S, Chui H, Dunten P, Hollenbeck M, MAthews I, Miller M, Moorhead P, Phizackerley RP, Smith C, Song J, van dem Bedem H, Ellis P, Kuhn P, McPhillips T, Sauter N, Sharp K, Tsyba I, Wolf G
JCSG, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 19018097)
Times cited: 88
- IMAge-based crystal detection: a MAchine-learning approach.
Liu R, Freund Y, Spraggon G
JCSG, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 19018095)
Times cited: 18
- Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis.
Pfleger BF, Kim Y, Nusca TD, MAltseva N, Lee JY, Rath CM, Scaglione JB, Janes BK, Anderson EC, BergMAn NH, Hanna PC, Joachimiak A, SherMAn DH
MCSG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 18955706)
PDB ID(s): 3DX5
Times cited: 35
- Protein Functional Surfaces: Global Shape MAtching and Local Spatial Alignments of Ligand Binding Sites.
Binkowski TA, Joachimiak A
MCSG, BMC Structural Biology
(Details)(Pubmed ID: 18954462)
Times cited: 44
- AutoMAted identification of complementarity determining regions (CDRs) reveals peculiar characteristics of CDRs and B cell epitopes.
Ofran Y, Schlessinger A, Rost B
NESG, Journal of Immunology
(Details)(Pubmed ID: 18941213)
Times cited: 38
- Genomic-scale prioritization of drug targets: the TDR Targets database.
Agüero F, Al-Lazikani B, Aslett M, BerriMAn M, Buckner FS, Campbell RK, Carmona S, Carruthers IM, Chan AW, Chen F, Crowther GJ, Doyle MA, Hertz-Fowler C, Hopkins AL, McAllister G, Nwaka S, Overington JP, Pain A, Paolini GV, Pieper U, Ralph SA, Riechers A, Roos DS, Sali A, Shanmugam D, Suzuki T, Van Voorhis WC, Verlinde CL
NYSGXRC, Nature reviews. Drug discovery
(Details)(Pubmed ID: 18927591)
Times cited: 189
- DcpS as a therapeutic target for spinal muscular atrophy.
Singh J, Salcius M, Liu SW, Staker BL, Mishra R, Thurmond J, Michaud G, MAttoon DR, Printen J, Christensen J, Bjornsson JM, Pollok BA, Kiledjian M, Stewart L, Jarecki J, Gurney ME
ATCG3D, ACS Chemical Biology
(Details)(Pubmed ID: 18839960)
PDB ID(s): 3BL7 3BL9 3BLA
Times cited: 82
- The 2.6 angstrom crystal structure of a huMAn A2A adenosine receptor bound to an antagonist.
Jaakola VP, Griffith MT, Hanson MA, Cherezov V, Chien EY, Lane JR, IjzerMAn AP, Stevens RC
ATCG3D+GPCR, Science
(Details)(Pubmed ID: 18832607)
PDB ID(s): 3EML
Times cited: 1331
- Simple host-guest chemistry to modulate the process of concentration and crystallization of membrane proteins by detergent capture in a microfluidic device.
Li L, Nachtergaele S, Seddon AM, Tereshko V, PonoMArenko N, IsMAgilov RF
ATCG3D, Journal of the American Chemical Society
(Details)(Pubmed ID: 18831551)
PDB ID(s): 3D48
Times cited: 23
- Physical protein-protein interactions predicted from microarrays.
Soong TT, Wrzeszczynski KO, Rost B
NESG, Bioinformatics
(Details)(Pubmed ID: 18829707)
Times cited: 23
- Large-scale evaluation of protein reductive methylation for improving protein crystallization.
Kim Y, Quartey P, Li H, Volkart L, Hatzos C, Chang C, Nocek B, Cuff M, Osipiuk J, Tan K, Fan Y, Bigelow L, MAltseva N, Wu R, Borovilos M, Duggan E, Zhou M, Binkowski TA, Zhang RG, Joachimiak A
MCSG, Nature Methods
(Details)(Pubmed ID: 18825126)
Times cited: 58
- Structural basis for RNA recognition by a type II poly(A)-binding protein.
Song J, McGivern JV, Nichols KW, MArkley JL, Sheets MD
CESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 18824697)
PDB ID(s): 2JWN
Times cited: 16
- Structural and thermodynamic characterization of T4 lysozyme mutants and the contribution of internal cavities to pressure denaturation.
Ando N, Barstow B, Baase WA, Fields A, MAtthews BW, Gruner SM
CHTSB, Biochemistry
(Details)(Pubmed ID: 18816066)
Times cited: 42
- Quantum chemical 13C(alpha) chemical shift calculations for protein NMR structure determination, refinement, and validation.
Vila JA, Aramini JM, Rossi P, Kuzin A, Su M, SeetharaMAn J, Xiao R, Tong L, Montelione GT, Scheraga HA
NESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 18787110)
Times cited: 47
- Histidine 55 of tryptophan 2,3-dioxygenase is not an active site base but regulates catalysis by controlling substrate binding.
Thackray SJ, BruckMAnn C, Anderson JL, Campbell LP, Xiao R, Zhao L, Mowat CG, Forouhar F, Tong L, ChapMAn SK
NESG, Biochemistry
(Details)(Pubmed ID: 18783250)
PDB ID(s): 2BK9 3E08
Times cited: 33
- Wheat germ cell-free translation, purification, and assembly of a functional huMAn stearoyl-CoA desaturase complex.
Goren MA, Fox BG
CESG, Protein Expression and Purification
(Details)(Pubmed ID: 18765284)
Times cited: 55
- Solution Structure of a Cyanobacterial Phytochrome GAF DoMAin in the Red-Light-Absorbing Ground State.
Cornilescu G, Ulijasz AT, Cornilescu CC, MArkley JL, Vierstra RD
CESG, Journal of Molecular Biology
(Details)(Pubmed ID: 18762196)
PDB ID(s): 2K2N
Times cited: 42
- TOPS++FATCAT: fast flexible structural alignment using constraints derived from TOPS+ Strings Model.
VeeraMAlai M, Ye Y, Godzik A
JCMM, BMC Bioinformatics
(Details)(Pubmed ID: 18759993)
Times cited: 25
- Structural basis for suppression of a host antiviral response by influenza A virus.
Das K, MA LC, Xiao R, Radvansky B, Aramini J, Zhao L, MArklund J, Kuo RL, Twu KY, Arnold E, Krug RM, Montelione GT
NESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 18725644)
PDB ID(s): 2RHK
Times cited: 133
- In vivo inactivation of the mycobacterial integral membrane stearoyl coenzyme A desaturase DesA3 by a C-terminus-specific degradation process.
Chang Y, Wesenberg GE, BingMAn CA, Fox BG
CESG, Journal of Bacteriology
(Details)(Pubmed ID: 18723625)
Times cited: 6
- OptiMAl design of therMAlly stable proteins.
Bannen RM, Suresh V, Phillips GN, Wright SJ, Mitchell JC
CESG, Bioinformatics
(Details)(Pubmed ID: 18723523)
Times cited: 8
- Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis.
Zhang C, Bitto E, Goff RD, Singh S, BingMAn CA, Griffith BR, AlberMAnn C, Phillips GN, Thorson JS
CESG, Chemistry & Biology
(Details)(Pubmed ID: 18721755)
PDB ID(s): 3D0Q 3D0R
Times cited: 40
- Solution NMR structure of the NlpC/P60 doMAin of lipoprotein Spr from Escherichia coli: structural evidence for a novel cysteine peptidase catalytic triad.
Aramini JM, Rossi P, Huang YJ, Zhao L, Jiang M, MAglaqui M, Xiao R, Locke J, Nair R, Rost B, Acton TB, Inouye M, Montelione GT
NESG, Biochemistry
(Details)(Pubmed ID: 18715016)
PDB ID(s): 2K1G
Times cited: 48
- Structure of HuMAn J-type Co-chaperone HscB Reveals a Tetracysteine Metal-binding DoMAin.
Bitto E, BingMAn CA, Bittova L, Kondrashov DA, Bannen RM, Fox BG, MArkley JL, Phillips GN
CESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 18713742)
PDB ID(s): 3BVO
Times cited: 28
- The classification of protein doMAins.
MArsden RL, Orengo CA
MCSG, Methods in Molecular Biology
(Details)(Pubmed ID: 18712300)
Times cited: 0
- Structure of an acetyl-CoA binding protein from Staphylococcus aureus representing a novel subfamily of GCN5-related N-acetyltransferase-like proteins.
Cort JR, Ramelot TA, Murray D, Acton TB, MA LC, Xiao R, Montelione GT, Kennedy MA
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 18709443)
PDB ID(s): 1R57 2H5M
Times cited: 6
- AutoMAted amino acid side-chain NMR assignment of proteins using (13)C- and (15)N-resolved 3D [ (1)H, (1)H]-NOESY.
Fiorito F, HerrMAnn T, Damberger FF, Wüthrich K
JCSG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 18709333)
Times cited: 56
- Structural characterization and reversal of the natural organophosphate resistance of a D-type esterase, Saccharomyces cerevisiae S-formylglutathione hydrolase.
Legler PM, KuMAran D, Swaminathan S, Studier FW, Millard CB
NYSGXRC, Biochemistry
(Details)(Pubmed ID: 18707125)
PDB ID(s): 1PV1
Times cited: 16
- Novel genes draMAtically alter regulatory network topology in amphioxus.
Zhang Q, ZMAsek CM, Dishaw LJ, Mueller MG, Ye Y, LitMAn GW, Godzik A
JCMM, Genome Biology
(Details)(Pubmed ID: 18680598)
Times cited: 32
- Evolutionarily conserved substrate substructures for autoMAted annotation of enzyme superfamilies.
Chiang RA, Sali A, Babbitt PC
NYSGXRC, PLoS Computational Biology
(Details)(Pubmed ID: 18670595)
Times cited: 17
- AllochroMAtium vinosum DsrC: solution-state NMR structure, redox properties, and interaction with DsrEFH, a protein essential for purple sulfur bacterial sulfur oxidation.
Cort JR, Selan U, Schulte A, Grimm F, Kennedy MA, Dahl C
NESG, Journal of Molecular Biology
(Details)(Pubmed ID: 18656485)
PDB ID(s): 1YX3
Times cited: 34
- Structure and dynamics of the P7 protein from the bacteriophage phi 12.
EryilMAz E, Benach J, Su M, SeetharaMAn J, Dutta K, Wei H, Gottlieb P, Hunt JF, Ghose R
NESG, Journal of Molecular Biology
(Details)(Pubmed ID: 18647606)
PDB ID(s): 2Q82
Times cited: 15
- BioinforMAtic method for protein therMAl stabilization by structural entropy optimization.
Bae E, Bannen RM, Phillips GN
CESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 18621726)
Times cited: 28
- Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus.
He X, Zhou J, Bartlam M, Zhang R, MA J, Lou Z, Li X, Li J, Joachimiak A, Zeng Z, Ge R, Rao Z, Liu Y
MCSG, Nature
(Details)(Pubmed ID: 18615018)
Times cited: 205
- Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1.
Chrencik JE, Brooun A, Zhang H, MAthews II, Hura GL, Foster SA, Perry JJ, Streiff M, RaMAge P, Widmer H, Bokoch GM, Tainer JA, Weckbecker G, Kuhn P
ATCG3D, Journal of Molecular Biology
(Details)(Pubmed ID: 18589439)
PDB ID(s): 3BJI
Times cited: 31
- Crystal structures of the effector-binding doMAin of repressor Central glycolytic gene Regulator from Bacillus subtilis reveal ligand-induced structural changes upon binding of several glycolytic intermediates.
Rezácová P, Kozísek M, Moy SF, Sieglová I, Joachimiak A, MAchius M, Otwinowski Z
MCSG, Molecular Microbiology
(Details)(Pubmed ID: 18554327)
PDB ID(s): 2OKG
Times cited: 18
- A specific cholesterol binding site is established by the 2.8 A structure of the huMAn beta2-adrenergic receptor.
Hanson MA, Cherezov V, Griffith MT, Roth CB, Jaakola VP, Chien EY, Velasquez J, Kuhn P, Stevens RC
ATCG3D+GPCR, Structure
(Details)(Pubmed ID: 18547522)
PDB ID(s): 3D4S
Times cited: 576
- Data MAnagement in structural genomics: an overview.
Haquin S, Oeuillet E, Pajon A, Harris M, Jones AT, van Tilbeurgh H, MArkley JL, Zolnai Z, Poupon A
CESG, Methods in Molecular Biology
(Details)(Pubmed ID: 18542857)
Times cited: 15
- Target selection for structural genomics: an overview.
MArsden RL, Orengo CA
MCSG, Methods in Molecular Biology
(Details)(Pubmed ID: 18542854)
Times cited: 19
- Ins and outs of MAjor facilitator superfamily antiporters.
Law CJ, MAloney PC, Wang DN
NYCOMPS, Annual review of microbiology
(Details)(Pubmed ID: 18537473)
Times cited: 264
- AutoMAted sequence-specific protein NMR assignment using the memetic algorithm MATCH.
Volk J, HerrMAnn T, Wüthrich K
JCSG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 18512031)
Times cited: 85
- Prediction of enzyme function by combining sequence similarity and protein interactions.
Espadaler J, Eswar N, Querol E, Avilés FX, Sali A, MArti-Renom MA, Oliva B
NYSGXRC, BMC Bioinformatics
(Details)(Pubmed ID: 18505562)
Times cited: 14
- Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM.
Singh S, McCoy JG, Zhang C, BingMAn CA, Phillips GN, Thorson JS
CESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 18502766)
PDB ID(s): 3BUS
Times cited: 39
- Crystal structure of the aquaglyceroporin PfAQP from the MAlarial parasite Plasmodium falciparum.
Newby ZE, O'Connell J, Robles-Colmenares Y, Khademi S, Miercke LJ, Stroud RM
CSMP, Nature Structural & Molecular Biology
(Details)(Pubmed ID: 18500352)
Times cited: 88
- Crystal structure of a putative lysostaphin peptidase from Vibrio cholerae.
RaguMAni S, KuMAran D, Burley SK, Swaminathan S
NYSGXRC, Proteins
(Details)(Pubmed ID: 18498110)
PDB ID(s): 2GU1
Times cited: 8
- Targeting the huMAn cancer pathway protein interaction network by structural genomics.
Huang YJ, Hang D, Lu LJ, Tong L, Gerstein MB, Montelione GT
NESG, Molecular & Cellular Proteomics
(Details)(Pubmed ID: 18487680)
Times cited: 51
- A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats
Beloglazova N, Brown G, ZimmerMAn MD, Proudfoot M, MAkarova KS, Kudritska M, Kochinyan S, Wang S, Chruszcz M, Minor W, Koonin EV, Edwards AM, Savchenko A, Yakunin AF
MCSG, Journal of Biological Chemistry
(Details)(Pubmed ID: 18482976)
PDB ID(s): 2I8E
Times cited: 122
- Microscale NMR screening of new detergents for membrane protein structural biology.
Zhang Q, Horst R, Geralt M, MA X, Hong WX, Finn MG, Stevens RC, Wüthrich K
JCSG, Journal of the American Chemical Society
(Details)(Pubmed ID: 18479092)
Times cited: 35
- Sequence specific resonance assignment via Multicanonical Monte Carlo search using an ABACUS approach.
LeMAk A, Steren CA, Arrowsmith CH, Llinás M
NESG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 18458824)
Times cited: 30
- Structural and functional characterization of a novel phosphatase from the Arabidopsis thaliana gene locus At1g05000.
Aceti DJ, Bitto E, Yakunin AF, Proudfoot M, BingMAn CA, Frederick RO, Sreenath HK, Vojtik FC, Wrobel RL, Fox BG, MArkley JL, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 18433060)
PDB ID(s): 1XRI
Times cited: 8
- Solution NMR structure of the SOS response protein YnzC from Bacillus subtilis.
Aramini JM, SharMA S, Huang YJ, Swapna GV, Ho CK, Shetty K, Cunningham K, MA LC, Zhao L, Owens LA, Jiang M, Xiao R, Liu J, Baran MC, Acton TB, Rost B, Montelione GT
NESG, Proteins
(Details)(Pubmed ID: 18431750)
PDB ID(s): 2HEP 2JVD
Times cited: 12
- Bacterial addiction module toxin Doc inhibits translation elongation through its association with the 30S ribosoMAl subunit.
Liu M, Zhang Y, Inouye M, Woychik NA
NESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 18398006)
Times cited: 82
- Structure and ligand binding of the soluble doMAin of a Thermotoga MAritiMA membrane protein of unknown function TM1634.
McCleverty CJ, Columbus L, Kreusch A, Lesley SA
JCSG, Protein Science
(Details)(Pubmed ID: 18369189)
Times cited: 4
- Proteomics analysis unravels the functional repertoire of coronavirus nonstructural protein 3.
NeuMAn BW, Joseph JS, Saikatendu KS, Serrano P, Chatterjee A, Johnson MA, Liao L, Klaus JP, Yates JR, Wüthrich K, Stevens RC, Buchmeier MJ, Kuhn P
JCSG, Journal of Virology
(Details)(Pubmed ID: 18367524)
Times cited: 77
- Analysis of solvent content and oligomeric states in protein crystals: does symmetry MAtter?
Chruszcz M, Potrzebowski W, ZimmerMAn MD, Grabowski M, Zheng H, Lasota P, Minor W
MCSG, Protein Science
(Details)(Pubmed ID: 18359856)
Times cited: 28
- Structural insight into the mechanism of substrate specificity and catalytic activity of an HD-doMAin phosphohydrolase: the 5'-deoxyribonucleotidase YfbR from Escherichia coli.
ZimmerMAn MD, Proudfoot M, Yakunin A, Minor W
MCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 18353368)
PDB ID(s): 2PAQ 1WPH
Times cited: 45
- Consistent blind protein structure generation from NMR chemical shift data.
Shen Y, Lange O, Delaglio F, Rossi P, Aramini JM, Liu G, Eletsky A, Wu Y, Singarapu KK, LeMAk A, Ignatchenko A, Arrowsmith CH, Szyperski T, Montelione GT, Baker D, Bax A
NESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 18326625)
Times cited: 531
- Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold.
Kozbial P, Xu Q, Chiu HJ, McMullan D, Krishna SS, Miller MD, Abdubek P, Acosta C, Astakhova T, Axelrod HL, Carlton D, Clayton T, Deller M, Duan L, Elias Y, Elsliger MA, Feuerhelm J, Grzechnik SK, Hale J, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, KoeseMA E, KuMAr A, MArciano D, Morse AT, Murphy KD, Nigoghossian E, Okach L, OomMAchen S, Reyes R, Rife CL, Spraggon G, Trout CV, van den Bedem H, Weekes D, White A, Wolf G, Zubieta C, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 18324683)
PDB ID(s): 2ETS 2HUJ
Times cited: 3
- NMR structure of the mengovirus Leader protein zinc-finger doMAin.
Cornilescu CC, Porter FW, Zhao KQ, Palmenberg AC, MArkley JL
CESG, FEBS Letters
(Details)(Pubmed ID: 18291103)
PDB ID(s): 2BAI
Times cited: 17
- The solution structure of ZNF593 from Homo sapiens reveals a zinc finger in a predominantly unstructured protein
Hayes PL, Lytle BL, VolkMAn BF, Peterson FC
CESG, Protein Science
(Details)(Pubmed ID: 18287285)
PDB ID(s): 1ZR9
Times cited: 11
- C-ME: a 3D community-based, real-time collaboration tool for scientific research and training.
Kolatkar A, Kennedy K, Halabuk D, Kunken J, MArrinucci D, Bethel K, GuzMAn R, Huckaby T, Kuhn P
ATCG3D, PLoS ONE
(Details)(Pubmed ID: 18286178)
Times cited: 4
- Structural basis for the catalytic mechanism of MAmMAlian 25-kDa thiamine triphosphatase.
Song J, Bettendorff L, Tonelli M, MArkley JL
CESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 18276586)
PDB ID(s): 2JMU
Times cited: 16
- Crystal structure of an ADP-ribosylated protein with a cytidine deaminase-like fold, but unknown function (TM1506), from Thermotoga MAritiMA at 2.70 A resolution.
Xu Q, Kozbial P, McMullan D, Krishna SS, Brittain SM, Ficarro SB, DiDonato M, Miller MD, Abdubek P, Axelrod HL, Chiu HJ, Clayton T, Duan L, Elsliger MA, Feuerhelm J, Grzechnik SK, Hale J, Han GW, Jaroszewski L, Klock HE, Morse AT, Nigoghossian E, Paulsen J, Reyes R, Rife CL, van den Bedem H, White A, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 18275082)
PDB ID(s): 1VK9
Times cited: 5
- Crystal structure of AICAR transformylase IMP cyclohydrolase (TM1249) from Thermotoga MAritiMA at 1.88 A resolution.
Axelrod HL, McMullan D, Krishna SS, Miller MD, Elsliger MA, Abdubek P, Ambing E, Astakhova T, Carlton D, Chiu HJ, Clayton T, Duan L, Feuerhelm J, Grzechnik SK, Hale J, Han GW, Haugen J, Jaroszewski L, Jin KK, Klock HE, Knuth MW, KoeseMA E, Morse AT, Nigoghossian E, Okach L, OomMAchen S, Paulsen J, Quijano K, Reyes R, Rife CL, van den Bedem H, Weekes D, White A, Wolf G, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 18260100)
PDB ID(s): 1ZCZ
Times cited: 5
- Molecular insights into the biosynthesis of the F420 coenzyme.
Forouhar F, Abashidze M, Xu H, Grochowski LL, SeetharaMAn J, Hussain M, Kuzin A, Chen Y, Zhou W, Xiao R, Acton TB, Montelione GT, Galinier A, White RH, Tong L
NESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 18252724)
PDB ID(s): 3C3D 3C3E 3CGW
Times cited: 24
- NMR structure of the peptidyl-tRNA hydrolase doMAin from Pseudomonas syringae expands the structural coverage of the hydrolysis doMAins of class 1 peptide chain release factors.
Singarapu KK, Xiao R, Acton T, Rost B, Montelione GT, Szyperski T
NESG, Proteins
(Details)(Pubmed ID: 18247350)
PDB ID(s): 2JVA
Times cited: 7
- A novel mode of dimerization via forMAtion of a glutaMAte anhydride crosslink in a protein crystal structure.
Agarwal R, Burley SK, Swaminathan S
NYSGXRC, Proteins
(Details)(Pubmed ID: 18247349)
PDB ID(s): 1SG9
Times cited: 0
- Structure of huMAn dual specificity protein phosphatase 23, VHZ, enzyme-substrate/product complex.
Agarwal R, Burley SK, Swaminathan S
NYSGXRC, Journal of Biological Chemistry
(Details)(Pubmed ID: 18245086)
PDB ID(s): 2IMG
Times cited: 21
- Protein production and purification.
Structural Genomics Consortium; Architecture et Fonction des MAcromolécules Biologiques; Berkeley Structural Genomics Center; China Structural Genomics Consortium; Integrated Center for Structure and Function Innovation; Israel Structural Proteomics Center; Joint Center for Structural Genomics; Midwest Center for Structural Genomics; New York Structural GenomiX Research Center for Structural Genomics; Northeast Structural Genomics Consortium; Oxford Protein Production Facility; Protein Sample Production Facility, MAx Delbrück Center for Molecular Medicine; RIKEN Structural Genomics/Proteomics Initiative; SPINE2-Complexes
ISFI+JCSG+MCSG+NESG+NYSGXRC, Nature Methods
(Details)(Pubmed ID: 18235434)
Times cited: 424
- Structural genomics: from genes to structures with valuable MAterials and MAny questions in between.
Fox BG, Goulding C, MAlkowski MG, Stewart L, Deacon A
ATCG3D+CESG+CHTSB+ISFI+JCSG, Nature Methods
(Details)(Pubmed ID: 18235432)
PDB ID(s):
Times cited: 31
- Intrinsically disordered gamMA-subunit of cGMP phosphodiesterase encodes functionally relevant transient secondary and tertiary structure.
Song J, Guo LW, Muradov H, Artemyev NO, Ruoho AE, MArkley JL
CESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 18230733)
PDB ID(s): 2JU4
Times cited: 62
- A Protein Structure Initiative approach to expression, purification, and in situ delivery of huMAn cytochrome b5 to membrane vesicles.
Sobrado P, Goren MA, James D, Amundson CK, Fox BG
CESG, Protein Expression and Purification
(Details)(Pubmed ID: 18226920)
Times cited: 20
- The solution structure of ribosoMAl protein S17E from Methanobacterium thermoautotrophicum: a structural homolog of the FF doMAin.
Wu B, Yee A, Huang YJ, Ramelot TA, Cort JR, Semesi A, Jung JW, Lee W, Montelione GT, Kennedy MA, Arrowsmith CH
NESG, Protein Science
(Details)(Pubmed ID: 18218711)
PDB ID(s): 1RQ6
Times cited: 2
- Solution structure of ribosoMAl protein L40E, a unique C4 zinc finger protein encoded by archaeon Sulfolobus solfataricus.
Wu B, Lukin J, Yee A, LeMAk A, Semesi A, Ramelot TA, Kennedy MA, Arrowsmith CH
NESG, Protein Science
(Details)(Pubmed ID: 18218710)
PDB ID(s): 2AYJ
Times cited: 8
- Solution structure of At3g28950 from Arabidopsis thaliana.
de la Cruz NB, Peterson FC, VolkMAn BF
CESG, Proteins
(Details)(Pubmed ID: 18214976)
PDB ID(s): 2JQV
Times cited: 0
- AutoMAted technologies and novel techniques to accelerate protein crystallography for structural genomics.
MAnjasetty BA, Turnbull AP, Panjikar S, Büssow K, Chance MR
NYSGXRC, Proteomics
(Details)(Pubmed ID: 18210369)
Times cited: 48
- NMR structure of protein Cgl2762 from Corynebacterium glutamicum implicated in DNA transposition reveals a helix-turn-helix motif attached to a flexibly disordered leucine zipper.
Singarapu KK, Xiao R, SukuMAran DK, Acton T, Montelione GT, Szyperski T
NESG, Proteins
(Details)(Pubmed ID: 18175328)
PDB ID(s): 2JN6
Times cited: 0
- X-ray crystal structure of the B component of Hemolysin BL from Bacillus cereus.
MAdegowda M, Eswaramoorthy S, Burley SK, Swaminathan S
NYSGXRC, Proteins
(Details)(Pubmed ID: 18175317)
PDB ID(s): 2NRJ
Times cited: 30
- Protein crystallography for non-crystallographers, or how to get the best (but not more) from published MAcromolecular structures.
Wlodawer A, Minor W, Dauter Z, Jaskolski M
MCSG, FEBS Journal
(Details)(Pubmed ID: 18034855)
Times cited: 103
- Biochemical and structural characterization of a novel family of cystathionine beta-synthase doMAin proteins fused to a Zn ribbon-like doMAin
Proudfoot M, Sanders SA, Singer A, Zhang R, Brown G, Binkowski A, Xu L, Lukin JA, Murzin AG, Joachimiak A, Arrowsmith CH, Edwards AM, Savchenko AV, Yakunin AF
MCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 18021800)
PDB ID(s): 1PVM 2QH1
Times cited: 38
- Crystal structure of 2-keto-3-deoxygluconate kinase (TM0067) from Thermotoga MAritiMA at 2.05 A resolution.
MAthews II, McMullan D, Miller MD, Canaves JM, Elsliger MA, Floyd R, Grzechnik SK, Jaroszewski L, Klock HE, KoeseMA E, Kovarik JS, Kreusch A, Kuhn P, McPhillips TM, Morse AT, Quijano K, Rife CL, Schwarzenbacher R, Spraggon G, Stevens RC, van den Bedem H, Weekes D, Wolf G, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 18004772)
PDB ID(s): 2AFB
Times cited: 4
- Combining the polymerase incomplete primer extension method for cloning and mutagenesis with microscreening to accelerate structural genomics efforts.
Klock HE, KoeseMA EJ, Knuth MW, Lesley SA
JCSG, Proteins
(Details)(Pubmed ID: 18004753)
Times cited: 190
- Structural basis for catalysis by onconase.
Lee JE, Bae E, BingMAn CA, Phillips GN, Raines RT
CESG, Journal of Molecular Biology
(Details)(Pubmed ID: 18001769)
PDB ID(s): 2GMK 2I5S
Times cited: 25
- Crystal structure of Homo sapiens protein LOC79017.
Bae E, BingMAn CA, Aceti DJ, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 17932939)
PDB ID(s): 2I5T
Times cited: 0
- Crystal structure of Arabidopsis thaliana cytokinin dehydrogenase.
Bae E, BingMAn CA, Bitto E, Aceti DJ, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 17886275)
PDB ID(s): 2EXR
Times cited: 10
- Crystal structure of aminopeptidase N from huMAn pathogen Neisseria meningitidis.
Nocek B, Mulligan R, Bargassa M, Collart F, Joachimiak A
MCSG, Proteins
(Details)(Pubmed ID: 17876832)
PDB ID(s): 2GTQ
Times cited: 28
- The structure of flavin-dependent tryptophan 7-halogenase RebH.
Bitto E, Huang Y, BingMAn CA, Singh S, Thorson JS, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 17876823)
PDB ID(s): 2O9Z 2OA1
Times cited: 44
- Crystal structure and putative function of sMAll Toprim doMAin-containing protein from Bacillus stearothermophilus
Rezácová P, Borek D, Moy SF, Joachimiak A, Otwinowski Z
MCSG, Proteins
(Details)(Pubmed ID: 17705269)
PDB ID(s): 2I5R 2FCJ
Times cited: 11
- Assessing model accuracy using the homology modeling autoMAtically software.
Bhattacharya A, Wunderlich Z, Monleon D, Tejero R, Montelione GT
NESG, Proteins
(Details)(Pubmed ID: 17640066)
Times cited: 27
- Structure and dynamics of gamMA-SNAP: insight into flexibility of proteins from the SNAP family.
Bitto E, BingMAn CA, Kondrashov DA, McCoy JG, Bannen RM, Wesenberg GE, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 17634982)
PDB ID(s): 2IFU
Times cited: 7
- Progress in the development of an alternative approach to MAcromolecular crystallization
Larson SB, Day JS, Nguyen C, Cudney R, McPherson A
CHTSB, Crystal Growth & Design
(Details)
Times cited: 16
2007
- Structural Genomics at the National Synchrotron Light Source
Rajashankar KR, Chance MR, Burley SK, Jiang J, Almo SC, Bresnick A, Huang R, He G, Chen H, Sullivan M, Toomey J, Radhakannan T, Franklin W, Sali A, Pieper U, McMAhan L
NYSGXRC, 2001 National Synchrotron Light Source Activity Report, 2-28 to 2-32. [Books and Proceedings]
(Details)
Times cited: 0
- NMR assignment of the doMAin 513-651 from the SARS-CoV nonstructural protein nsp3.
Chatterjee A, Johnson MA, Serrano P, Pedrini B, Wüthrich K
JCSG, Biomolecular NMR Assignments
(Details)(Pubmed ID: 19636862)
PDB ID(s): 2RNK 2JZF
Times cited: 3
- Comparative protein structure modeling using MODELLER.
Eswar N, Webb B, MArti-Renom MA, MAdhusudhan MS, Eramian D, Shen MY, Pieper U, Sali A
NYSGXRC, Current Protocols in Protein Science
(Details)(Pubmed ID: 18429317)
Times cited: 296
- Effect of low-complexity regions on protein structure determination.
Bannen RM, BingMAn CA, Phillips GN
CESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 18302007)
Times cited: 9
- A graphical approach to tracking and reporting target status in structural genomics.
Pan X, Wesenberg GE, MArkley JL, Fox BG, Phillips GN, BingMAn CA
CESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 18236171)
Times cited: 4
- Structural genomics of protein phosphatases.
Almo SC, Bonanno JB, Sauder JM, Emtage S, Dilorenzo TP, MAlashkevich V, WasserMAn SR, Swaminathan S, Eswaramoorthy S, Agarwal R, KuMAran D, MAdegowda M, RaguMAni S, Patskovsky Y, Alvarado J, RaMAgopal UA, Faber-Barata J, Chance MR, Sali A, Fiser A, Zhang ZY, Lawrence DS, Burley SK
NYSGXRC, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 18058037)
PDB ID(s): 2FH7
Times cited: 81
- The structural basis of cyclic diguanylate signal transduction by PilZ doMAins.
Benach J, Swaminathan SS, TaMAyo R, HandelMAn SK, Folta-Stogniew E, Ramos JE, Forouhar F, Neely H, SeetharaMAn J, Camilli A, Hunt JF
NESG, EMBO Journal
(Details)(Pubmed ID: 18034161)
PDB ID(s): 1YWU 1YLN 2GJG 1W25
Times cited: 150
- Structural genomics.
Sali A, LiMA CD, Kostic M
NYSGXRC, Structure
(Details)(Pubmed ID: 17997955)
Times cited: 2
- NMR spectroscopic and analytical ultracentrifuge analysis of membrane protein detergent complexes
MAslennikov I, Johnson C, Riek R, Choe S, Kwiatkowski W
CSMP, BMC Structural Biology
(Details)(Pubmed ID: 17988403)
Times cited: 23
- SMAll-scale, semi-autoMAted purification of eukaryotic proteins for structure determination.
Frederick RO, BergeMAn L, Blommel PG, Bailey LJ, McCoy JG, Song J, Meske L, BingMAn CA, Riters M, Dillon NA, Kunert J, Yoon JW, Lim A, Cassidy M, Bunge J, Aceti DJ, Primm JG, MArkley JL, Phillips GN, Fox BG
CESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 17985212)
Times cited: 21
- In situ proteolysis for protein crystallization and structure determination.
Dong A, Xu X, Edwards AM, Chang C, Chruszcz M, Cuff M, Cymborowski M, Di Leo R, Egorova O, Evdokimova E, Filippova E, Gu J, Guthrie J, Ignatchenko A, Joachimiak A, KlosterMAnn N, Kim Y, Korniyenko Y, Minor W, Que Q, Savchenko A, Skarina T, Tan K, Yakunin A, Yee A, Yim V, Zhang R, Zheng H, Akutsu M, Arrowsmith C, Avvakumov GV, Bochkarev A, Dahlgren LG, Dhe-Paganon S, Dimov S, Dombrovski L, Finerty P, Flodin S, Flores A, Gräslund S, Hammerström M, HerMAn MD, Hong BS, Hui R, Johansson I, Liu Y, Nilsson M, Nedyalkova L, Nordlund P, NyMAn T, Min J, Ouyang H, Park HW, Qi C, Rabeh W, Shen L, Shen Y, SukuMArd D, Tempel W, Tong Y, Tresagues L, Vedadi M, Walker JR, Weigelt J, Welin M, Wu H, Xiao T
MCSG, Nature Methods
(Details)(Pubmed ID: 17982461)
Times cited: 152
- AutoMAted robotic harvesting of protein crystals-addressing a critical bottleneck or instrumentation overkill?
Rupp B
TB, European BioPharmaceutical Review
(Details)(Pubmed ID: 17965947)
Times cited: 9
- Comparison of apo- and heme-bound crystal structures of a truncated huMAn heme oxygenase-2.
Bianchetti CM, Yi L, Ragsdale SW, Phillips GN
CESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 17965015)
PDB ID(s): 2Q32
Times cited: 34
- High-resolution crystal structure of an engineered huMAn beta2-adrenergic G protein-coupled receptor.
Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Kuhn P, Weis WI, Kobilka BK, Stevens RC
ATCG3D+GPCR, Science
(Details)(Pubmed ID: 17962520)
PDB ID(s): 2RH1
Times cited: 2299
- GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function.
Rosenbaum DM, Cherezov V, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Yao XJ, Weis WI, Stevens RC, Kobilka BK
ATCG3D, Science
(Details)(Pubmed ID: 17962519)
Times cited: 985
- Surprising complexity of the ancestral apoptosis network.
ZMAsek CM, Zhang Q, Ye Y, Godzik A
JCMM, Genome Biology
(Details)(Pubmed ID: 17958905)
Times cited: 57
- High-resolution structure prediction and the crystallographic phase problem.
Qian B, RaMAn S, Das R, Bradley P, McCoy AJ, Read RJ, Baker D
NMHRCM, Nature
(Details)(Pubmed ID: 17934447)
Times cited: 213
- Creating protein models from electron-density MAps using particle-filtering methods.
DiMAio F, Kondrashov DA, Bitto E, Soni A, BingMAn CA, Phillips GN, Shavlik JW
CESG, Bioinformatics
(Details)(Pubmed ID: 17933855)
Times cited: 20
- Size and shape of detergent micelles determined by sMAll-angle X-ray scattering.
Lipfert J, Columbus L, Chu VB, Lesley SA, Doniach S
JCSG, Journal of Physical Chemistry B
(Details)(Pubmed ID: 17924686)
Times cited: 133
- XtalPred: a web server for prediction of protein crystallizability.
Slabinski L, Jaroszewski L, Rychlewski L, Wilson IA, Lesley SA, Godzik A
JCSG, Bioinformatics
(Details)(Pubmed ID: 17921170)
Times cited: 144
- Bis-methionyl coordination in the crystal structure of the heme-binding doMAin of the streptococcal cell surface protein Shp.
Aranda R, Worley CE, Liu M, Bitto E, Cates MS, Olson JS, Lei B, Phillips GN
CESG, Journal of Molecular Biology
(Details)(Pubmed ID: 17920629)
PDB ID(s): 2Q7A
Times cited: 41
- Nearest-neighbor effects on backbone alpha and beta carbon chemical shifts in proteins.
Wang L, Eghbalnia HR, MArkley JL
CESG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 17899393)
Times cited: 15
- Expression of recombinant G-protein coupled receptors for structural biology.
MAncia F, Hendrickson WA
NYCOMPS, Molecular bioSystems
(Details)(Pubmed ID: 17882334)
Times cited: 18
- Functional linkages can reveal protein complexes for structure determination.
Kim SM, Bowers PM, Pal D, Strong M, Terwilliger TC, KaufMAnn M, Eisenberg D
ISFI, Structure
(Details)(Pubmed ID: 17850747)
PDB ID(s):
Times cited: 2
- Structures of proteins of biomedical interest from the Center for Eukaryotic Structural Genomics.
Phillips GN, Fox BG, MArkley JL, VolkMAn BF, Bae E, Bitto E, BingMAn CA, Frederick RO, McCoy JG, Lytle BL, Pierce BS, Song J, Twigger SN
CESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 17786587)
Times cited: 8
- Nuclear MAgnetic resonance structure of the N-terminal doMAin of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus.
Serrano P, Johnson MA, Almeida MS, Horst R, HerrMAnn T, Joseph JS, NeuMAn BW, SubraMAnian V, Saikatendu KS, Buchmeier MJ, Stevens RC, Kuhn P, Wüthrich K
JCSG, Journal of Virology
(Details)(Pubmed ID: 17728234)
PDB ID(s): 2GRI 2IDY
Times cited: 31
- Natively unstructured regions in proteins identified from contact predictions.
Schlessinger A, Punta M, Rost B
NESG+NYCOMPS, Bioinformatics
(Details)(Pubmed ID: 17709338)
Times cited: 81
- The crystal structure of the effector-binding doMAin of the trehalose repressor TreR from Bacillus subtilis 168 reveals a unique quarternary assembly.
Rezáčová P, Krejčiříková V, Borek D, Moy SF, Joachimiak A, Otwinowski Z
MCSG, Proteins
(Details)(Pubmed ID: 17705272)
PDB ID(s): 2OGG
Times cited: 10
- Structural and functional studies of the abundant tegument protein ORF52 from murine gamMAherpesvirus 68.
Benach J, Wang L, Chen Y, Ho CK, Lee S, SeetharaMAn J, Xiao R, Acton TB, Montelione GT, Deng H, Sun R, Tong L
NESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 17699518)
PDB ID(s): 2OA5
Times cited: 18
- A steric block in translation caused by the antibiotic spectinomycin.
Borovinskaya MA, Shoji S, Holton JM, Fredrick K, Cate JH
CSMP, ACS Chemical Biology
(Details)(Pubmed ID: 17696316)
Times cited: 73
- Structure of an amide bond forming F(420):gamMA-glutamyl ligase from Archaeoglobus fulgidus -- a member of a new family of non-ribosoMAl peptide synthases
Nocek B, Evdokimova E, Proudfoot M, Kudritska M, Grochowski LL, White RH, Savchenko A, Yakunin AF, Edwards A, Joachimiak A
MCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 17669425)
PDB ID(s): 2G9I 2PHN
Times cited: 17
- Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Borovinskaya MA, Pai RD, Zhang W, Schuwirth BS, Holton JM, Hirokawa G, Kaji H, Kaji A, Cate JH
CSMP, Nature Structural & Molecular Biology
(Details)(Pubmed ID: 17660832)
Times cited: 193
- Reactivation of methionine synthase from Thermotoga MAritiMA (TM0268) requires the downstream gene product TM0269.
Huang S, RoMAnchuk G, Pattridge K, Lesley SA, Wilson IA, MAtthews RG, Ludwig M
JCSG, Protein Science
(Details)(Pubmed ID: 17656578)
Times cited: 4
- Crystal structure of MtnX phosphatase from Bacillus subtilis at 2.0 A resolution provides a structural basis for bipartite phosphomonoester hydrolysis of 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate.
Xu Q, Saikatendu KS, Krishna SS, McMullan D, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod HL, Carlton D, Chiu HJ, Clayton T, DiDonato M, Duan L, Elsliger MA, Feuerhelm J, Grzechnik SK, Hale J, Hampton E, Han GW, Haugen J, Jaroszewski L, Jin KK, Klock HE, Knuth MW, KoeseMA E, Miller MD, Morse AT, Nigoghossian E, Okach L, OomMAchen S, Paulsen J, Reyes R, Rife CL, Schwarzenbacher R, van den Bedem H, White A, Wolf G, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 17654724)
PDB ID(s): 2FEA
Times cited: 6
- Identification and structural characterization of heme binding in a novel dye-decolorizing peroxidase, TyrA.
Zubieta C, Joseph R, Krishna SS, McMullan D, Kapoor M, Axelrod HL, Miller MD, Abdubek P, Acosta C, Astakhova T, Carlton D, Chiu HJ, Clayton T, Deller MC, Duan L, Elias Y, Elsliger MA, Feuerhelm J, Grzechnik SK, Hale J, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, KuMAr A, MArciano D, Morse AT, Murphy KD, Nigoghossian E, Okach L, OomMAchen S, Reyes R, Rife CL, Schimmel P, Trout CV, van den Bedem H, Weekes D, White A, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 17654547)
PDB ID(s): 2IIZ
Times cited: 54
- Crystal structures of two novel dye-decolorizing peroxidases reveal a beta-barrel fold with a conserved heme-binding motif.
Zubieta C, Krishna SS, Kapoor M, Kozbial P, McMullan D, Axelrod HL, Miller MD, Abdubek P, Ambing E, Astakhova T, Carlton D, Chiu HJ, Clayton T, Deller MC, Duan L, Elsliger MA, Feuerhelm J, Grzechnik SK, Hale J, Hampton E, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, KuMAr A, MArciano D, Morse AT, Nigoghossian E, Okach L, OomMAchen S, Reyes R, Rife CL, Schimmel P, van den Bedem H, Weekes D, White A, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 17654545)
PDB ID(s): 2GVK 2HAG
Times cited: 55
- Single protein production (SPP) system in Escherichia coli.
Suzuki M, MAo L, Inouye M
NYCOMPS, Nature Protocols
(Details)(Pubmed ID: 17641648)
Times cited: 50
- X-ray structure of imidazolonepropionase from Agrobacterium tumefaciens at 1.87 A resolution.
Tyagi R, KuMAran D, Burley SK, Swaminathan S
NYSGXRC, Proteins
(Details)(Pubmed ID: 17640072)
PDB ID(s): 2PUZ
Times cited: 2
- Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 A resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases.
Krishna SS, Tautz L, Xu Q, McMullan D, Miller MD, Abdubek P, Ambing E, Astakhova T, Axelrod HL, Carlton D, Chiu HJ, Clayton T, DiDonato M, Duan L, Elsliger MA, Grzechnik SK, Hale J, Hampton E, Han GW, Haugen J, Jaroszewski L, Jin KK, Klock HE, Knuth MW, KoeseMA E, Morse AT, Mustelin T, Nigoghossian E, OomMAchen S, Reyes R, Rife CL, van den Bedem H, Weekes D, White A, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 17636569)
PDB ID(s): 2F46
Times cited: 6
- The multifunctional huMAn p100 protein 'hooks' methylated ligands
Shaw N, Zhao M, Cheng C, Xu H, Saarikettu J, Li Y, Da Y, Yao Z, Silvennoinen O, Yang J, Liu ZJ, Wang BC, Rao Z
SECSG, Nature Structural & Molecular Biology
(Details)(Pubmed ID: 17632523)
Times cited: 57
- The closed MTIP-myosin A-tail complex from the MAlaria parasite invasion MAchinery.
Bosch J, Turley S, Roach CM, Daly TM, BergMAn LW, Hol WG
SGPP, Journal of Molecular Biology
(Details)(Pubmed ID: 17628590)
Times cited: 38
- A combinatorial approach to studying protein complex composition by employing size-exclusion chroMAtography and proteome analysis.
Li SS, Giometti CS
MCSG, Journal of Separation Science
(Details)(Pubmed ID: 17623436)
Times cited: 4
- Computational protein function prediction: are we MAking progress?
Godzik A, Jambon M, Friedberg I
JCSG, Cellular and Molecular Life Science
(Details)(Pubmed ID: 17611711)
Times cited: 36
- HIFI-C: a robust and fast method for determining NMR couplings from adaptive 3D to 2D projections.
Cornilescu G, Bahrami A, Tonelli M, MArkley JL, Eghbalnia HR
CESG, Journal of Biomolecular NMR
(Details)(Pubmed ID: 17610130)
Times cited: 13
- The relationships between oxidase and synthase activities of flavin dependent thymidylate synthase (FDTS).
Chernyshev A, FleischMAnn T, Koehn EM, Lesley SA, Kohen A
JCSG, Chemical Communications
(Details)(Pubmed ID: 17609801)
Times cited: 11
- Structure-based activity prediction for an enzyme of unknown function.
HerMAnn JC, MArti-Arbona R, Fedorov AA, Fedorov E, Almo SC, Shoichet BK, Raushel FM
NYSGXRC, Nature
(Details)(Pubmed ID: 17603473)
PDB ID(s): 2PLM
Times cited: 183
- Crystal structure of a transcriptional regulator TM1030 from Thermotoga MAritiMA solved by an unusual MAD experiment.
Koclega KD, Chruszcz M, ZimmerMAn MD, Cymborowski M, Evdokimova E, Minor W
MCSG, Journal of Structural Biology
(Details)(Pubmed ID: 17588774)
PDB ID(s): 1Z77
Times cited: 7
- Functional insights from structural genomics.
Forouhar F, Kuzin A, SeetharaMAn J, Lee I, Zhou W, Abashidze M, Chen Y, Yong W, Janjua H, Fang Y, Wang D, Cunningham K, Xiao R, Acton TB, Pichersky E, Klessig DF, Porter CW, Montelione GT, Tong L
NESG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 17588214)
PDB ID(s): 1RTY 1SQS 1TM0 1Z6P 2HD3 2NV4 2OYS
Times cited: 23
- Crystal structures of TM0549 and NE1324--two orthologs of E. coli AHAS isozyme III sMAll regulatory subunit
Petkowski JJ, Chruszcz M, ZimmerMAn MD, Zheng H, Skarina T, Onopriyenko O, Cymborowski MT, Koclega KD, Savchenko A, Edwards A, Minor W
MCSG, Protein Science
(Details)(Pubmed ID: 17586771)
PDB ID(s): 2FGC 2PC6
Times cited: 14
- The 2.2 A resolution crystal structure of Bacillus cereus Nif3-family protein YqfO reveals a conserved dimetal-binding motif and a regulatory doMAin.
Godsey MH, Minasov G, Shuvalova L, Brunzelle JS, Vorontsov II, Collart FR, Anderson WF
MCSG, Protein Science
(Details)(Pubmed ID: 17586767)
PDB ID(s): 2GX8
Times cited: 13
- Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands.
Zhou HB, Nettles KW, Bruning JB, Kim Y, Joachimiak A, SharMA S, Carlson KE, Stossi F, Katzenellenbogen BS, Greene GL, Katzenellenbogen JA
MCSG, Chemistry & Biology
(Details)(Pubmed ID: 17584613)
Times cited: 53
- Two-color selection for amplified co-production of proteins in MAmMAlian cells.
Assur Z, Schieren I, Hendrickson WA, MAncia F
NYCOMPS, Protein Expression and Purification
(Details)(Pubmed ID: 17574435)
Times cited: 3
- The AnnoLite and AnnoLyze programs for comparative annotation of protein structures.
MArti-Renom MA, Rossi A, Al-Shahrour F, Davis FP, Pieper U, Dopazo J, Sali A
NYSGXRC, BMC Bioinformatics
(Details)(Pubmed ID: 17570147)
Times cited: 27
- The 2006 autoMAted function prediction meeting.
Rodrigues AP, Grant BJ, Godzik A, Friedberg I
JCSG, BMC Bioinformatics
(Details)(Pubmed ID: 17570143)
Times cited: 7
- Expression of 25 huMAn ABC transporters in the yeast Pichia pastoris and characterization of the purified ABCC3 ATPase activity.
Chloupková M, Pickert A, Lee JY, Souza S, Trinh YT, Connelly SM, Dumont ME, Dean M, Urbatsch IL
CHTSB, Biochemistry
(Details)(Pubmed ID: 17569508)
Times cited: 36
- Solution structure of a membrane-anchored ubiquitin-fold (MUB) protein from Homo sapiens.
de la Cruz NB, Peterson FC, Lytle BL, VolkMAn BF
CESG, Protein Science
(Details)(Pubmed ID: 17567738)
PDB ID(s): 2GOW
Times cited: 4
- Crystal structure of homoserine O-succinyltransferase from Bacillus cereus at 2.4 A resolution.
Zubieta C, Krishna SS, McMullan D, Miller MD, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod HL, Carlton D, Chiu HJ, Clayton T, Deller M, DiDonato M, Duan L, Elsliger MA, Grzechnik SK, Hale J, Hampton E, Han GW, Haugen J, Jaroszewski L, Jin KK, Klock HE, Knuth MW, KoeseMA E, KuMAr A, MArciano D, Morse AT, Nigoghossian E, OomMAchen S, Reyes R, Rife CL, van den Bedem H, Weekes D, White A, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 17546672)
PDB ID(s): 2GHR
Times cited: 8
- Activation of inhibitors by sortase triggers irreversible modification of the active site.
MAresso AW, Wu R, Kern JW, Zhang R, Janik D, Missiakas DM, Duban ME, Joachimiak A, Schneewind O
MCSG, Journal of Biological Chemistry
(Details)(Pubmed ID: 17545669)
PDB ID(s): 2OQW
Times cited: 59
- The first agMAtine/cadaverine aminopropyl transferase: biochemical and structural characterization of an enzyme involved in polyamine biosynthesis in the hyperthermophilic archaeon Pyrococcus furiosus.
Cacciapuoti G, Porcelli M, Moretti MA, Sorrentino F, Concilio L, Zappia V, Liu ZJ, Tempel W, Schubot F, Rose JP, Wang BC, Brereton PS, Jenney FE, Adams MW
SECSG, Journal of Bacteriology
(Details)(Pubmed ID: 17545282)
Times cited: 20
- Solution NMR structure of Escherichia coli ytfP expands the structural coverage of the UPF0131 protein doMAin family.
Aramini JM, Huang YJ, Swapna GV, Cort JR, Rajan PK, Xiao R, Shastry R, Acton TB, Liu J, Rost B, Kennedy MA, Montelione GT
NESG, Proteins
(Details)(Pubmed ID: 17523190)
PDB ID(s): 1XHS
Times cited: 4
- The neurobiologist's guide to structural biology: a primer on why MAcromolecular structure MAtters and how to evaluate structural data
Minor DL
CSMP, Neuron
(Details)(Pubmed ID: 17521566)
Times cited: 31
- Curved EFC/F-BAR-doMAin dimers are joined end to end into a filament for membrane invagination in endocytosis.
ShiMAda A, Niwa H, Tsujita K, Suetsugu S, Nitta K, Hanawa-Suetsugu K, Akasaka R, Nishino Y, ToyaMA M, Chen L, Liu ZJ, Wang BC, YaMAmoto M, Terada T, Miyazawa A, Tanaka A, Sugano S, Shirouzu M, NagayaMA K, Takenawa T, YokoyaMA S
SECSG, Cell
(Details)(Pubmed ID: 17512409)
Times cited: 252
- LinkHub: a SeMAntic Web system that facilitates cross-database queries and inforMAtion retrieval in proteomics.
Smith AK, Cheung KH, Yip KY, Schultz M, Gerstein MK
NESG, BMC Bioinformatics
(Details)(Pubmed ID: 17493288)
Times cited: 18
- DBAli tools: mining the protein structure space.
MArti-Renom MA, Pieper U, MAdhusudhan MS, Rossi A, Eswar N, Davis FP, Al-Shahrour F, Dopazo J, Sali A
NYSGXRC, Nucleic Acids Research
(Details)(Pubmed ID: 17478513)
Times cited: 23
- Real-time footprinting of DNA in the first kinetically significant intermediate in open complex forMAtion by Escherichia coli RNA polymerase.
Davis CA, BingMAn CA, Landick R, Record MT, Saecker RM
CESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 17470797)
Times cited: 55
- Structural plasticity in the oestrogen receptor ligand-binding doMAin.
Nettles KW, Bruning JB, Gil G, O'Neill EE, Nowak J, Guo Y, Hughs A, Kim Y, DeSombre ER, Dilis R, Hanson RN, Joachimiak A, Greene GL
MCSG, EMBO Reports
(Details)(Pubmed ID: 17468738)
Times cited: 87
- How U38, 39, and 40 of MAny tRNAs become the targets for pseudouridylation by TruA.
Hur S, Stroud RM
CSMP, Molecular Cell
(Details)(Pubmed ID: 17466622)
Times cited: 45
- Crystal structure of TM1030 from Thermotoga MAritiMA at 2.3 A resolution reveals molecular details of its transcription repressor function.
PremkuMAr L, Rife CL, Sri Krishna S, McMullan D, Miller MD, Abdubek P, Ambing E, Astakhova T, Axelrod HL, Canaves JM, Carlton D, Chiu HJ, Clayton T, DiDonato M, Duan L, Elsliger MA, Feuerhelm J, Floyd R, Grzechnik SK, Hale J, Hampton E, Han GW, Haugen J, Jaroszewski L, Jin KK, Klock HE, Knuth MW, KoeseMA E, Kovarik JS, Kreusch A, Levin I, McPhillips TM, Morse AT, Nigoghossian E, Okach L, OomMAchen S, Paulsen J, Quijano K, Reyes R, Rezezadeh F, Rodionov D, Schwarzenbacher R, Spraggon G, van den Bedem H, White A, Wolf G, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 17444523)
PDB ID(s): 1ZKG
Times cited: 5
- Crystal structure of RNase T, an exoribonuclease involved in tRNA MAturation and end turnover.
Zuo Y, Zheng H, Wang Y, Chruszcz M, Cymborowski M, Skarina T, Savchenko A, MAlhotra A, Minor W
MCSG, Structure
(Details)(Pubmed ID: 17437714)
PDB ID(s): 2F96
Times cited: 29
- Blocking S-adenosylmethionine synthesis in yeast allows selenomethionine incorporation and multiwavelength anoMAlous dispersion phasing.
MAlkowski MG, Quartley E, FriedMAn AE, Babulski J, Kon Y, Wolfley J, Said M, Luft JR, Phizicky EM, DeTitta GT, Grayhack EJ
CHTSB, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 17426150)
Times cited: 37
- Solution structure of huMAn sorting nexin 22.
Song J, Zhao KQ, NewMAn CL, Vinarov DA, MArkley JL
CESG, Protein Science
(Details)(Pubmed ID: 17400918)
PDB ID(s): 2ETT
Times cited: 10
- The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families.
Yooseph S, Sutton G, Rusch DB, Halpern AL, Williamson SJ, Remington K, Eisen JA, Heidelberg KB, MAnning G, Li W, Jaroszewski L, Cieplak P, Miller CS, Li H, MAshiyaMA ST, Joachimiak MP, van Belle C, Chandonia JM, Soergel DA, Zhai Y, Natarajan K, Lee S, Raphael BJ, Bafna V, FriedMAn R, Brenner SE, Godzik A, Eisenberg D, Dixon JE, Taylor SS, Strausberg RL, Frazier M, Venter JC
JCSG, PLoS Biology
(Details)(Pubmed ID: 17355171)
Times cited: 521
- Inhibition of huMAn pancreatic ribonuclease by the huMAn ribonuclease inhibitor protein.
Johnson RJ, McCoy JG, BingMAn CA, Phillips GN, Raines RT
CESG, Journal of Molecular Biology
(Details)(Pubmed ID: 17350650)
PDB ID(s): 1Z7X
Times cited: 80
- Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint.
MArsden RL, Lewis TA, Orengo CA
MCSG, BMC Bioinformatics
(Details)(Pubmed ID: 17349043)
Times cited: 28
- Cautionary tail: the presence of an N-terminal tag on dynein light-chain Roadblock/LC7 affects its interaction with a functional partner.
Song J, MArkley JL
CESG, Protein and Peptide Letters
(Details)(Pubmed ID: 17346231)
PDB ID(s): 1Y4O
Times cited: 13
- An extremely SAD case: structure of a putative redox-enzyme MAturation protein from Archaeoglobus fulgidus at 3.4 A resolution.
Kirillova O, Chruszcz M, Shumilin IA, Skarina T, Gorodichtchenskaia E, Cymborowski M, Savchenko A, Edwards A, Minor W
MCSG, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 17327672)
PDB ID(s): 2O9X 1ZE0
Times cited: 23
- Efficient optimization of crystallization conditions by MAnipulation of drop volume ratio and temperature.
Luft JR, Wolfley JR, Said MI, Nagel RM, Lauricella AM, Smith JL, Thayer MH, Veatch CK, Snell EH, MAlkowski MG, Detitta GT
CHTSB, Protein Science
(Details)(Pubmed ID: 17327388)
Times cited: 29
- Crystal structure of AGR_C_4470p from Agrobacterium tumefaciens.
Vorobiev SM, Neely H, SeetharaMAn J, MA LC, Xiao R, Acton TB, Montelione GT, Tong L
NESG, Protein Science
(Details)(Pubmed ID: 17322535)
PDB ID(s): 2HQV
Times cited: 1
- Structure and interactions of the first three RNA recognition motifs of splicing factor prp24.
Bae E, Reiter NJ, BingMAn CA, Kwan SS, Lee D, Phillips GN, Butcher SE, Brow DA
CESG, Journal of Molecular Biology
(Details)(Pubmed ID: 17320109)
PDB ID(s): 2GHP
Times cited: 30
- Diffraction-based autoMAted crystal centering.
Song J, MAthew D, Jacob SA, Corbett L, Moorhead P, Soltis SM
CHTSB, Journal of Synchrotron Radiation
(Details)(Pubmed ID: 17317920)
Times cited: 45
- Towards fully autoMAted structure-based function prediction in structural genomics: a case study
Watson JD, Sanderson S, Ezersky A, Savchenko A, Edwards A, Orengo C, Joachimiak A, Laskowski RA, Thornton JM
MCSG, Journal of Molecular Biology
(Details)(Pubmed ID: 17316683)
Times cited: 61
- The conserved CPH doMAins of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization doMAin of p53.
Kaustov L, Lukin J, LeMAk A, Duan S, Ho M, Doherty R, Penn LZ, Arrowsmith CH
NESG, Journal of Biological Chemistry
(Details)(Pubmed ID: 17298945)
PDB ID(s): 2JNG
Times cited: 36
- Structural rigidity of a large cavity-containing protein revealed by high-pressure crystallography.
Collins MD, Quillin ML, Hummer G, MAtthews BW, Gruner SM
CHTSB, Journal of Molecular Biology
(Details)(Pubmed ID: 17292912)
Times cited: 46
- Isotropic bicelles stabilize the functional form of a sMAll multidrug-resistance pump for NMR structural studies.
Poget SF, Cahill SM, Girvin ME
NYCOMPS, Journal of the American Chemical Society
(Details)(Pubmed ID: 17284035)
Times cited: 50
- Using three-phase flow of immiscible liquids to prevent coalescence of droplets in microfluidic channels: criteria to identify the third liquid and validation with protein crystallization.
Chen DL, Li L, Reyes S, Adamson DN, IsMAgilov RF
ATCG3D, Langmuir
(Details)(Pubmed ID: 17279722)
Times cited: 57
- Remedial strategies in structural proteomics: expression, purification, and crystallization of the Vav1/Rac1 complex.
Brooun A, Foster SA, Chrencik JE, Chien EY, Kolatkar AR, Streiff M, RaMAge P, Widmer H, Weckbecker G, Kuhn P
ATCG3D, Protein Expression and Purification
(Details)(Pubmed ID: 17275330)
Times cited: 7
- Crystal structure of a transcription regulator (TM1602) from Thermotoga MAritiMA at 2.3 A resolution.
Weekes D, Miller MD, Krishna SS, McMullan D, McPhillips TM, Acosta C, Canaves JM, Elsliger MA, Floyd R, Grzechnik SK, Jaroszewski L, Klock HE, KoeseMA E, Kovarik JS, Kreusch A, Morse AT, Quijano K, Spraggon G, van den Bedem H, Wolf G, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 17256761)
PDB ID(s): 1J5Y
Times cited: 5
- Multiple alignment of membrane proteins for measuring residual dipolar couplings using lanthanide ions bound to a sMAll metal chelator.
Kamen DE, Cahill SM, Girvin ME
NYCOMPS, Journal of the American Chemical Society
(Details)(Pubmed ID: 17253688)
Times cited: 21
- Structure of dNTP-inducible dNTP triphosphohydrolase: insight into broad specificity for dNTPs and triphosphohydrolase-type hydrolysis.
Kondo N, Nakagawa N, Ebihara A, Chen L, Liu ZJ, Wang BC, YokoyaMA S, Kuramitsu S, MAsui R
SECSG, Acta Crystallographica Section D: Biological Crystallography
(Details)(Pubmed ID: 17242516)
PDB ID(s): 2DQB
Times cited: 20
- Oocyte CD9 is enriched on the microvillar membrane and required for norMAl microvillar shape and distribution.
Runge KE, Evans JE, He ZY, Gupta S, McDonald KL, Stahlberg H, PriMAkoff P, Myles DG
CSMP, Developmental Biology
(Details)(Pubmed ID: 17239847)
Times cited: 96
- Using an alignment of fragment strings for comparing protein structures.
Friedberg I, Harder T, Kolodny R, Sitbon E, Li Z, Godzik A
JCSG, Bioinformatics
(Details)(Pubmed ID: 17237095)
Times cited: 23
- Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains.
Zhou HB, Sheng S, Compton DR, Kim Y, Joachimiak A, SharMA S, Carlson KE, Katzenellenbogen BS, Nettles KW, Greene GL, Katzenellenbogen JA
MCSG, Journal of Medicinal Chemistry
(Details)(Pubmed ID: 17228884)
Times cited: 29
- Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.
Huang DT, Hunt HW, Zhuang M, Ohi MD, Holton JM, SchulMAn BA
CSMP, Nature
(Details)(Pubmed ID: 17220875)
Times cited: 134
- XANES measurements of the rate of radiation daMAge to selenomethionine side chains.
Holton JM
CSMP, Journal of Synchrotron Radiation
(Details)(Pubmed ID: 17211072)
Times cited: 41
- Novel beta-barrel fold in the nuclear MAgnetic resonance structure of the replicase nonstructural protein 1 from the severe acute respiratory syndrome coronavirus.
Almeida MS, Johnson MA, HerrMAnn T, Geralt M, Wüthrich K
JCSG, Journal of Virology
(Details)(Pubmed ID: 17202208)
PDB ID(s): 2HSX
Times cited: 34
- Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase.
Forouhar F, Anderson JL, Mowat CG, Vorobiev SM, Hussain A, Abashidze M, BruckMAnn C, Thackray SJ, SeetharaMAn J, Tucker T, Xiao R, MA LC, Zhao L, Acton TB, Montelione GT, ChapMAn SK, Tong L
NESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 17197414)
PDB ID(s): 2NWB 2NW7 2NW8 2NW9
Times cited: 126
- Structure of aspartoacylase, the brain enzyme impaired in Canavan disease.
Bitto E, BingMAn CA, Wesenberg GE, McCoy JG, Phillips GN
CESG, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 17194761)
PDB ID(s): 2GU2 2I3C
Times cited: 47
- Crystallization and preliminary crystallographic analysis of molybdenum-cofactor biosynthesis protein C from Thermus thermophilus.
Kanaujia SP, Ranjani CV, Jeyakanthan J, Baba S, Chen L, Liu ZJ, Wang BC, Nishida M, Ebihara A, Shinkai A, Kuramitsu S, Shiro Y, Sekar K, YokoyaMA S
SECSG, Acta Crystallographica Section F: Structural Biology and Crystallization Communications
(Details)(Pubmed ID: 17183168)
Times cited: 4
- Structure and dynamics of UDP-glucose pyrophosphorylase from Arabidopsis thaliana with bound UDP-glucose and UTP.
McCoy JG, Bitto E, BingMAn CA, Wesenberg GE, Bannen RM, Kondrashov DA, Phillips GN
CESG, Journal of Molecular Biology
(Details)(Pubmed ID: 17178129)
PDB ID(s): 1Z90 2ICX 2ICY
Times cited: 31
- Three-dimensional structure determined for a subunit of huMAn tRNA splicing endonuclease (Sen15) reveals a novel dimeric fold.
Song J, MArkley JL
CESG, Journal of Molecular Biology
(Details)(Pubmed ID: 17166513)
PDB ID(s): 2GW6
Times cited: 8
- Structural analysis of the plakin doMAin of bullous pemphigoid antigen1 (BPAG1) suggests that plakins are members of the spectrin superfamily.
Jefferson JJ, Ciatto C, Shapiro L, Liem RK
NYSGXRC, Journal of Molecular Biology
(Details)(Pubmed ID: 17161423)
PDB ID(s): 2IAK
Times cited: 48
- A high-throughput approach to protein structure analysis.
MAnjasetty BA, Shi W, Zhan C, Fiser A, Chance MR
NYSGXRC, Genetic Engineering
(Details)(Pubmed ID: 17153936)
Times cited: 7
- Solution structure of a sMAll protein containing a fluorinated side chain in the core.
Cornilescu G, Hadley EB, Woll MG, MArkley JL, GellMAn SH, Cornilescu CC
CESG, Protein Science
(Details)(Pubmed ID: 17123960)
PDB ID(s): 2JM0
Times cited: 16
- NMR structure and binding studies confirm that PA4608 from Pseudomonas aeruginosa is a PilZ doMAin and a c-di-GMP binding protein.
Ramelot TA, Yee A, Cort JR, Semesi A, Arrowsmith CH, Kennedy MA
NESG, Proteins
(Details)(Pubmed ID: 17096419)
PDB ID(s): 1YWU
Times cited: 53
- Characteristics affecting expression and solubilization of yeast membrane proteins.
White MA, Clark KM, Grayhack EJ, Dumont ME
CHTSB, Journal of Molecular Biology
(Details)(Pubmed ID: 17078969)
Times cited: 34
- The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzyMAtic function.
Goulding CW, Bowers PM, Segelke B, Lekin T, Kim CY, Terwilliger TC, Eisenberg D
ISFI, Journal of Molecular Biology
(Details)(Pubmed ID: 17064730)
PDB ID(s): 1Z6K
Times cited: 24
- 2dx--user-friendly iMAge processing for 2D crystals.
Gipson B, Zeng X, Zhang ZY, Stahlberg H
CSMP, Journal of Structural Biology
(Details)(Pubmed ID: 17055742)
Times cited: 117
- Three-dimensional transmission electron microscopy of MAcromolecular Assemblies
Renault L, Stahlberg H
CSMP, Scanning
(Details)
Times cited: 0
- Comparative Protein Structure Modeling Using MODELLER
Eswar N, MArti-Renom MA
NYSGXRC, Current Protocols in BioinforMAtics, I. John Wiley & Sons, ed. [Books and Proceedings]
(Details)
Times cited: 296
- A guide to autoMAtion and data handling in protein crystallization
Rupp B
TB, Protein Crystallization Strategies for Structural Genomics, Editor: Naomi Cheyen, International University Line [Books and Proceedings]
(Details)
Times cited: 0
2006
- Structural basis of CoA recognition by the Pyrococcus single-doMAin CoA-binding proteins.
HiyaMA TB, Zhao M, Kitago Y, Yao M, Sekine S, Terada T, Kuroishi C, Liu ZJ, Rose JP, Kuramitsu S, Shirouzu M, Watanabe N, YokoyaMA S, Tanaka I, Wang BC
SECSG, Journal of Structural and Functional Genomics
(Details)(Pubmed ID: 17342453)
Times cited: 2
- Micelle-induced folding of spinach thylakoid soluble phosphoprotein of 9 kDa and its functional implications.
Song J, Lee MS, Carlberg I, Vener AV, MArkley JL
CESG, Biochemistry
(Details)(Pubmed ID: 17176085)
PDB ID(s): 2FFT
Times cited: 11
- Structural insight into the self-sacrifice mechanism of enediyne resistance.
Singh S, Hager MH, Zhang C, Griffith BR, Lee MS, Hallenga K, MArkley JL, Thorson JS
CESG, ACS Chemical Biology
(Details)(Pubmed ID: 17168523)
PDB ID(s): 1ZXF 2GKD 2L65
Times cited: 23
- Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins.
Li L, Mustafi D, Fu Q, Tereshko V, Chen DL, Tice JD, IsMAgilov RF
ATCG3D, Proceedings of the National Academy of Sciences of the United States of America
(Details)(Pubmed ID: 17159147)
PDB ID(s): 2I5N
Times cited: 169
- A homotetrameric kinesin-5, KLP61F, bundles microtubules and antagonizes Ncd in motility assays.
Tao L, Mogilner A, Civelekoglu-Scholey G, WollMAn R, Evans J, Stahlberg H, Scholey JM
CSMP, Current Biology
(Details)(Pubmed ID: 17141610)
Times cited: 87
- Structure of Arabidopsis thaliana At1g77540 protein, a miniMAl acetyltransferase from the COG2388 family.
Tyler RC, Bitto E, Berndsen CE, BingMAn CA, Singh S, Lee MS, Wesenberg GE, Denu JM, Phillips GN, MArkley JL
CESG, Biochemistry
(Details)(Pubmed ID: 17128971)
PDB ID(s): 1XMT 2EVN 2IL4
Times cited: 7
- FAST-NMR: functional annotation screening technology using NMR spectroscopy.
Mercier KA, Baran M, RaMAnathan V, Revesz P, Xiao R, Montelione GT, Powers R
NESG, Journal of the American Chemical Society
(Details)(Pubmed ID: 17117882)
Times cited: 34
- Searching for silver bullets: an alternative strategy for crystallizing MAcromolecules.
McPherson A, Cudney B
CHTSB, Journal of Structural Biology
(Details)(Pubmed ID: 17101277)
Times cited: 116
- Time-controlled microfluidic seeding in nL-volume droplets to separate nucleation and growth stages of protein crystallization.
Gerdts CJ, Tereshko V, Yadav MK, Dementieva I, Collart F, Joachimiak A, Stevens RC, Kuhn P, Kossiakoff A, IsMAgilov RF
ATCG3D+MCSG, Angewandte Chemie International Edition in English
(Details)(Pubmed ID: 17099920)
PDB ID(s): 2H1J
Times cited: 92
- Solution structure of a single-doMAin thiosulfate sulfurtransferase from Arabidopsis thaliana.
Cornilescu G, Vinarov DA, Tyler EM, MArkley JL, Cornilescu CC
CESG, Protein Science
(Details)(Pubmed ID: 17088324)
PDB ID(s): 1TQ1
Times cited: 8
- Representing and comparing protein structures as paths in three-dimensional space.
Zhi D, Krishna SS, Cao H, Pevzner P, Godzik A
JCSG, BMC Bioinformatics
(Details)(Pubmed ID: 17052359)
Times cited: 8
- Structures of huMAn insulin-degrading enzyme reveal a new substrate recognition mechanism.
Shen Y, Joachimiak A, Rosner MR, Tang WJ
MCSG, Nature
(Details)(Pubmed ID: 17051221)
Times cited: 220
- X-ray crystal structures of the conserved hypothetical proteins from Arabidopsis thaliana gene loci At5g11950 and AT2g37210.
Jeon WB, Allard ST, BingMAn CA, Bitto E, Han BW, Wesenberg GE, Phillips GN
CESG, Proteins
(Details)(Pubmed ID: 17048257)
PDB ID(s): 1YDH 2A33
Times cited: 11
- Experimental and computational assessment of conditionally essential genes in Escherichia coli.
Joyce AR, Reed JL, White A, Edwards R, OsterMAn A, Baba T, Mori H, Lesely SA, Palsson BØ, Agarwalla S
JCSG, Journal of Bacteriology
(Details)(Pubmed ID: 17012394)
Times cited: 151
- Using fragment cocktail crystallography to assist inhibitor design of TrypanosoMA brucei nucleoside 2-deoxyribosyltransferase.
Bosch J, Robien MA, Mehlin C, Boni E, Riechers A, Buckner FS, Van Voorhis WC, Myler PJ, Worthey EA, DeTitta G, Luft JR, Lauricella A, Gulde S, Anderson LA, Kalyuzhniy O, Neely HM, Ross J, Earnest TN, Soltis M, Schoenfeld L, Zucker F, Merritt EA, Fan E, Verlinde CL, Hol WG
SGPP, Journal of Medicinal Chemistry
(Details)(Pubmed ID: 17004709)
PDB ID(s): 2A0K
Times cited: 48
- Comparative structural analysis of a novel glutathioneS-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 A resolution.
Kosloff M, Han GW, Krishna SS, Schwarzenbacher R, Fasnacht M, Elsliger MA, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod HL, Canaves JM, Carlton D, Chiu HJ, Clayton T, DiDonato M, Duan L, Feuerhelm J, Grittini C, Grzechnik SK, Hale J, Hampton E, Haugen J, Jaroszewski L, Jin KK, Johnson H, Klock HE, Knuth MW, KoeseMA E, Kreusch A, Kuhn P, Levin I, McMullan D, Miller MD, Morse AT, Moy K, Nigoghossian E, Okach L, OomMAchen S, Page R, Paulsen J, Quijano K, Reyes R, Rife CL, Sims E, Spraggon G, Sridhar V, Stevens RC, van den Bedem H, Velasquez J, White A, Wolf G, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 16988933)
PDB ID(s): 2FNO
Times cited: 7
- MiniMAlist representations and the importance of nearest neighbor effects in protein folding simulations.
Colubri A, Jha AK, Shen MY, Sali A, Berry RS, Sosnick TR, Freed KF
NYSGXRC, Journal of Molecular Biology
(Details)(Pubmed ID: 16982067)
Times cited: 29
- Localization of binding sites in protein structures by optimization of a composite scoring function.
Rossi A, MArti-Renom MA, Sali A
NYSGXRC, Protein Science
(Details)(Pubmed ID: 16963645)
Times cited: 17
- Outcome of a workshop on archiving structural models of biological MAcromolecules.
BerMAn HM, Burley SK, Chiu W, Sali A, Adzhubei A, Bourne PE, Bryant SH, Dunbrack RL, Fidelis K, Frank J, Godzik A, Henrick K, Joachimiak A, HeyMAnn B, Jones D, MArkley JL, Moult J, Montelione GT, Orengo C, RossMAnn MG, Rost B, Saibil H, Schwede T, Standley DM, Westbrook JD
NESGC+NYSGXRC, Structure
(Details)(Pubmed ID: 16955948)
PDB ID(s):
Times cited: 32
- Structure of the SCAN doMAin from the tumor suppressor protein MZF1.
Peterson FC, Hayes PL, Waltner JK, Heisner AK, Jensen DR, Sander TL, VolkMAn BF
CESG, Journal of Molecular Biology
(Details)(Pubmed ID: 16950398)
PDB ID(s): 2FI2
Times cited: 16
- Crystal structure of an ORFan protein (TM1622) from Thermotoga MAritiMA at 1.75 A resolution reveals a fold similar to the Ran-binding protein Mog1p.
Xu Q, Krishna SS, McMullan D, Schwarzenbacher R, Miller MD, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod HL, Canaves JM, Carlton D, Chiu HJ, Clayton T, DiDonato M, Duan L, Elsliger MA, Feuerhelm J, Grzechnik SK, Hale J, Hampton E, Han GW, Haugen J, Jaroszewski L, Jin KK, Klock HE, Knuth MW, KoeseMA E, Kreusch A, Kuhn P, Morse AT, Nigoghossian E, Okach L, OomMAchen S, Paulsen J, Quijano K, Reyes R, Rife CL, Spraggon G, Stevens RC, van den Bedem H, White A, Wolf G, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA
JCSG, Proteins
(Details)(Pubmed ID: 16948158)
PDB ID(s): 1VR8
Times cited: 5
- Solution NMR in structural genomics.
Yee A, GutMAnas A, Arrowsmith CH
NESG, Current Opinion in Structural Biology
(Details)(Pubmed ID: 16942869)
Times cited: 34
- Wheat germ cell-free platform for eukaryotic protein production.
Vinarov DA, Loushin NewMAn CL, MArkley JL
CESG, FEBS Journal
