37th Mid-Atlantic Protein Crystallography MeetingUniversity of Virginia
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| Thursday, June 7 | ||
| 1:00--3:30 PM | Registration, posters, exhibitors | |
| 3:45 PM | Welcome and opening remarks |
Robert Kretsinger (University of Virginia) Ariel Gomez (Vice-President for Research, University of Virginia) Keynote Speaker Introduction: Wladek Minor (University of Virginia) |
| 4:00 PM | Keynote Speaker | |
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Andrzej Joachimiak Professor, University of Chicago Director, Structural Biology Center, Argonne National Laboratory Principal Investigator, Midwest Center for Structural Genomics "Structural Genomics - Expanding Protein Fold Space and Discovering Function"
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| 5:15--8:00 PM | Reception & dinner | |
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| Friday, June 8 | ||
| Talk and poster code: T = Talk (25 minutes) E = Exhibitor Talk (15 minutes) S = Student Poster P = Poster M = Methods Talk (30 minutes) |
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| 7:30--8:30 AM | Coffee & continental breakfast, posters, exhibitors | |
| 8:00--12:00 AM | Registration | |
| Session 1 (Chair, Robert Kretsinger) | ||
| 8:30--8:55 AM | Christian Biertumpfel (NIH, NIDDK) | |
| T1. Crystal Structure of T4 Endonuclease VII Resolving a Holliday Junction | ||
| 8:55--9:20 AM | Jacek Lubkowski (NCI-Frederick) | |
| T2. Structural Basis of the CCR6-Mediated Chemotaxis of Human Beta-Defensins | ||
| 9:20--9:45 AM | Heping Zheng (University of Virginia) | |
| T3. Analysis of Metal Environments in Protein Structures | ||
| 9:45--10:10 AM | Joseph Ferrara (Rigaku Americas Corporation) | |
| T4. Phasing with In-house Softer X-ray Radiation | ||
| 10:10--10:25 AM | Ruth Crowe (QIAGEN) | |
| E1. Process Development: Scaling Up Human IL-1L | ||
| 10:25--10:40 AM | (Formulatrix) | |
| TBA | ||
| 10:40--11:10 AM | Coffee break, posters, exhibitors | |
| Session 2 (Chair, Fraydoon Rastinejad) | ||
| 11:15--11:40 AM | Kinlin Chao (UMBI, CARB) | |
| T5. Structure of Human Hyaluronidase 1: a Hyaluronan Hydrolase and Tumor Growth Regulator | ||
| 11:40--12:05 PM | Michael Murray (Wake Forest University) | |
| T6. Human Glycolate Oxidase 1: a Structural and Biochemical Examination of a Possible Target for Hyperoxaluria Treatment | ||
| 12:05--12:30 PM | Jean Jakoncic (BNL, NSLS) | |
| T7. The Structure of PhnI; a Dioxygenase from Sphingomonas CHY-1 | ||
| 12:30--12:45 PM | Joseph Ferrara (Rigaku Americas Corporation) | |
| E3. HomeLabs vs. Synchrotrons: The Facts Will Surprise You | ||
| 12:45--1:00 PM | (TTP Labtech) | |
| TBA | ||
| 1:00--2:00 PM | Lunch, posters, exhibitors | |
| Session 3 (Chair, Wladek Minor) | ||
| 2:00--2:25 PM | Eric Ortlund (UNC - Chapel Hill) | |
| T8. Functional Anatomy of Phospholipid Binding and Regulation of Phosphoinositide Homeostasis by Proteins of the Sec14-Superfamily | ||
| 2:25--2:50 PM | Chao Tu (NCI-Frederick) | |
| T9. Structural Basis for p53 Deactivation by Hotspot Mutation R282Q as Revealed by X-Ray Crystallography and Molecular Dynamics Simulations | ||
| 2:50--3:15 PM | Jamie Wallen (Wake Forest University) | |
| T10. Crystallographic and Kinetic Analyses of the Coenzyme A-Disulfide Reductase-Rhodanese Homology Domain Protein from Bacillus anthracis Indicate Novel Function | ||
| 3:15--3:40 PM | Igor Pechik (UMBI, CARB) | |
| T11. Structural Basis for the Two-Stage Mechanism of Thrombin-Induced Fibrin Assembly | ||
| 3:40--3:55 PM | (Oxford Diffraction) | |
| TBA | ||
| 3:55--4:15 PM | Business Meeting | |
| 4:15--7:00 PM | Coffee & Refreshments, posters, vendors | |
| Primary Poster Session Student Poster Competition Judging |
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| Saturday, June 9 | ||
| 7:30--8:30 AM | Coffee & continental breakfast, posters, exhibitors | |
| Methods 1 (Chair, Michael Wiener) | ||
| 8:30--9:00 AM | David Cooper (University of Virginia) | |
| M1. Crystallization by SER when Serendipity Fails | ||
| 9:00--9:30 AM | Abraham Lenhoff (University of Delaware) | |
| M2. Protein Interaction Measurements as a Guide to Crystallization | ||
| 9:30--10:00 AM | Robert Rose (North Caroline State University) | |
| M3. Small Angle Scattering as an Approach to Model a Multi-Protein Complex on the Insulin Promoter | ||
| 10:00--10:30 AM | Coffee break, posters, exhibitors | |
| Methods 2 (Chair, Zygmunt Derewenda) | ||
| 10:30--11:00 AM | Cameron Mura (University of California, San Diego) | |
| M4. A Structural Biologist's Guide to Molecular Dynamics Simulations | ||
| 11:00--11:30 AM | Scott Stagg (The Scripps Research Institute) | |
| M5. Appion: an Automated Pipeline for Single Particle Reconstructions | ||
| 11:30--12:00 PM | Wladek Minor (University of Virginia) | |
| M6. HKL3000: Towards the Future of Protein Crystallography | ||
| 12:00 PM | Closing Remarks | |
| 12:00--1:00 PM | Lunch | |
| 1:30-- PM | HKL3000 Practical Course (Jordan Hall) | |
| The HKL3000 session will be run by Wladek Minor. A key part of this Practical Course is for participants to bring/use their own "unsolved" data. Please email Wladek Minor (wladek@iwonka.med.virginia.edu) for instructions and information. | ||